Atg16l1 (autophagy related 16-like 1) - Rat Genome Database

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Pathways
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Gene: Atg16l1 (autophagy related 16-like 1) Rattus norvegicus
Analyze
Symbol: Atg16l1
Name: autophagy related 16-like 1
RGD ID: 1310631
Description: Predicted to enable GTPase binding activity; identical protein binding activity; and protein-membrane adaptor activity. Predicted to be involved in several processes, including autophagosome assembly; defense response to virus; and negative stranded viral RNA replication. Predicted to act upstream of or within macroautophagy and telencephalon development. Predicted to be located in several cellular components, including autophagosome; sperm midpiece; and vacuole-isolation membrane contact site. Predicted to be part of Atg12-Atg5-Atg16 complex. Predicted to be active in autophagosome membrane; endolysosome membrane; and phagophore assembly site membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Orthologous to human ATG16L1 (autophagy related 16 like 1); PARTICIPATES IN autophagy pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: APG16 autophagy 16-like; APG16 autophagy 16-like (S. cerevisiae); Apg16l; ATG16 autophagy related 16-like 1; ATG16 autophagy related 16-like 1 (S. cerevisiae); autophagy related 16-like 1 (S. cerevisiae); autophagy-related 16-like 1; autophagy-related 16-like 1 (yeast); autophagy-related protein 16-1; LOC363278; WD repeat domain 30; Wdr30
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,869,839 - 95,905,354 (+)NCBIGRCr8
mRatBN7.2988,420,737 - 88,457,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx996,846,724 - 96,882,032 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,982,902 - 102,018,214 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,350,405 - 100,385,741 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,879,876 - 94,915,231 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,879,745 - 94,915,228 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,599,174 - 94,634,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,712,122 - 86,747,370 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1986,895,541 - 86,929,665 (+)NCBI
Celera985,830,765 - 85,865,957 (+)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Bassoon Controls Presynaptic Autophagy through Atg5. Okerlund ND, etal., Neuron. 2017 Feb 22;93(4):897-913.e7. doi: 10.1016/j.neuron.2017.01.026.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Hepatic interferon regulatory factor 8 expression mediates liver ischemia/reperfusion injury in mice. Shi G, etal., Biochem Pharmacol. 2021 Oct;192:114728. doi: 10.1016/j.bcp.2021.114728. Epub 2021 Aug 13.
9. LC3 conjugation system in mammalian autophagy. Tanida I, etal., Int J Biochem Cell Biol. 2004 Dec;36(12):2503-18.
10. Aliskiren ameliorates pressure overload-induced heart hypertrophy and fibrosis in mice. Weng LQ, etal., Acta Pharmacol Sin. 2014 Aug;35(8):1005-14. doi: 10.1038/aps.2014.45. Epub 2014 Jul 7.
11. Mammalian autophagy: core molecular machinery and signaling regulation. Yang Z and Klionsky DJ, Curr Opin Cell Biol. 2010 Apr;22(2):124-31. Epub 2009 Dec 23.
Additional References at PubMed
PMID:8889548   PMID:12665549   PMID:20562859   PMID:21220506   PMID:22740627   PMID:23392225   PMID:24089209   PMID:24550300   PMID:24954904   PMID:25891078   PMID:26845845   PMID:28860495  
PMID:29634390   PMID:30208760   PMID:33818130   PMID:33843019   PMID:35503135  


Genomics

Comparative Map Data
Atg16l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,869,839 - 95,905,354 (+)NCBIGRCr8
mRatBN7.2988,420,737 - 88,457,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx996,846,724 - 96,882,032 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09101,982,902 - 102,018,214 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09100,350,405 - 100,385,741 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0994,879,876 - 94,915,231 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,879,745 - 94,915,228 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,599,174 - 94,634,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,712,122 - 86,747,370 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1986,895,541 - 86,929,665 (+)NCBI
Celera985,830,765 - 85,865,957 (+)NCBICelera
Cytogenetic Map9q35NCBI
ATG16L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382233,251,673 - 233,295,669 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2233,210,051 - 233,295,674 (+)EnsemblGRCh38hg38GRCh38
GRCh372234,160,319 - 234,204,315 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,824,956 - 233,869,059 (+)NCBINCBI36Build 36hg18NCBI36
Celera2227,881,745 - 227,925,836 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2225,960,992 - 226,005,094 (+)NCBIHuRef
CHM1_12234,166,299 - 234,210,402 (+)NCBICHM1_1
T2T-CHM13v2.02233,739,756 - 233,783,753 (+)NCBIT2T-CHM13v2.0
Atg16l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,683,730 - 87,720,150 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,683,592 - 87,720,150 (+)EnsemblGRCm39 Ensembl
GRCm38187,756,007 - 87,792,428 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,755,870 - 87,792,428 (+)EnsemblGRCm38mm10GRCm38
MGSCv37189,652,646 - 89,688,997 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36189,587,242 - 89,623,593 (+)NCBIMGSCv36mm8
Celera190,714,013 - 90,750,352 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.44NCBI
Atg16l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554532,880,928 - 2,917,581 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554532,884,497 - 2,917,581 (-)NCBIChiLan1.0ChiLan1.0
ATG16L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,853,482 - 135,897,461 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,868,447 - 135,912,425 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B120,479,534 - 120,523,563 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B239,392,990 - 239,436,766 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B239,392,990 - 239,436,766 (+)Ensemblpanpan1.1panPan2
ATG16L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,761,034 - 44,800,033 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,761,185 - 44,798,672 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2545,256,465 - 45,295,672 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02545,020,993 - 45,060,197 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2545,020,983 - 45,060,197 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12544,945,410 - 44,984,592 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,791,409 - 44,830,551 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02544,946,602 - 44,985,778 (+)NCBIUU_Cfam_GSD_1.0
Atg16l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303186,929,271 - 186,966,233 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365253,972,558 - 4,010,514 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365253,973,574 - 4,010,442 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATG16L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,651,298 - 133,693,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115133,651,294 - 133,693,472 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215147,677,835 - 147,718,756 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATG16L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110119,286,609 - 119,331,226 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10119,286,751 - 119,333,267 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604080,173,329 - 80,218,029 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atg16l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248435,805,069 - 5,838,741 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248435,797,725 - 5,838,768 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atg16l1
165 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:464
Count of miRNA genes:239
Interacting mature miRNAs:299
Transcripts:ENSRNOT00000024445
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)98636963192058970Rat

Markers in Region
BE120484  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2988,450,809 - 88,450,973 (+)MAPPERmRatBN7.2
Rnor_6.0994,908,513 - 94,908,676NCBIRnor6.0
Rnor_5.0994,627,833 - 94,627,996UniSTSRnor5.0
RGSC_v3.4986,740,651 - 86,740,814UniSTSRGSC3.4
Celera985,859,238 - 85,859,401UniSTS
Cytogenetic Map9q35UniSTS
RH137932  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2988,449,736 - 88,449,911 (+)MAPPERmRatBN7.2
Rnor_6.0994,907,440 - 94,907,614NCBIRnor6.0
Rnor_5.0994,626,760 - 94,626,934UniSTSRnor5.0
RGSC_v3.4986,739,578 - 86,739,752UniSTSRGSC3.4
Celera985,858,165 - 85,858,339UniSTS
Cytogenetic Map9q35UniSTS
RH139068  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2988,453,825 - 88,453,993 (+)MAPPERmRatBN7.2
Rnor_6.0994,911,525 - 94,911,692NCBIRnor6.0
Rnor_5.0994,630,845 - 94,631,012UniSTSRnor5.0
RGSC_v3.4986,743,667 - 86,743,834UniSTSRGSC3.4
Celera985,862,254 - 85,862,421UniSTS
Cytogenetic Map9q35UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 51 35 19 35 8 11 74 34 34 11 8
Low 1 6 6 6 1 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA925215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB605957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB782885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK473997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK481169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO393878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EV774911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000024445   ⟹   ENSRNOP00000024445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)Ensembl
Rnor_6.0 Ensembl994,880,053 - 94,915,228 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080482   ⟹   ENSRNOP00000075135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)Ensembl
Rnor_6.0 Ensembl994,879,745 - 94,915,204 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114063   ⟹   ENSRNOP00000097226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl988,422,038 - 88,457,529 (+)Ensembl
RefSeq Acc Id: NM_001108809   ⟹   NP_001102279
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,870,013 - 95,905,354 (+)NCBI
mRatBN7.2988,422,181 - 88,457,529 (+)NCBI
Rnor_6.0994,880,053 - 94,915,228 (+)NCBI
Rnor_5.0994,599,174 - 94,634,551 (+)NCBI
RGSC_v3.4986,712,122 - 86,747,370 (+)RGD
Celera985,830,765 - 85,865,957 (+)RGD
Sequence:
RefSeq Acc Id: XM_006245419   ⟹   XP_006245481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,869,839 - 95,905,354 (+)NCBI
mRatBN7.2988,421,916 - 88,457,530 (+)NCBI
Rnor_6.0994,879,876 - 94,915,231 (+)NCBI
Rnor_5.0994,599,174 - 94,634,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006245420   ⟹   XP_006245482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,869,840 - 95,905,354 (+)NCBI
mRatBN7.2988,421,942 - 88,457,530 (+)NCBI
Rnor_6.0994,879,876 - 94,915,231 (+)NCBI
Rnor_5.0994,599,174 - 94,634,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039083917   ⟹   XP_038939845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,869,839 - 95,905,354 (+)NCBI
mRatBN7.2988,420,737 - 88,457,530 (+)NCBI
RefSeq Acc Id: XM_063267450   ⟹   XP_063123520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,869,839 - 95,905,354 (+)NCBI
RefSeq Acc Id: XM_063267451   ⟹   XP_063123521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,884,824 - 95,905,354 (+)NCBI
RefSeq Acc Id: XM_063267452   ⟹   XP_063123522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8995,884,824 - 95,905,354 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001102279   ⟸   NM_001108809
- UniProtKB: D3ZFK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245481   ⟸   XM_006245419
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K9U6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245482   ⟸   XM_006245420
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GLZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075135   ⟸   ENSRNOT00000080482
RefSeq Acc Id: ENSRNOP00000024445   ⟸   ENSRNOT00000024445
RefSeq Acc Id: XP_038939845   ⟸   XM_039083917
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000097226   ⟸   ENSRNOT00000114063
RefSeq Acc Id: XP_063123520   ⟸   XM_063267450
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063123521   ⟸   XM_063267451
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063123522   ⟸   XM_063267452
- Peptide Label: isoform X6
Protein Domains
Autophagy-related protein

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K9U6-F1-model_v2 AlphaFold A0A0G2K9U6 1-623 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696840
Promoter ID:EPDNEW_R7364
Type:multiple initiation site
Name:Atg16l1_1
Description:autophagy related 16-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0994,879,907 - 94,879,967EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310631 AgrOrtholog
BioCyc Gene G2FUF-26835 BioCyc
Ensembl Genes ENSRNOG00000017913 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024445 ENTREZGENE
  ENSRNOT00000024445.4 UniProtKB/TrEMBL
  ENSRNOT00000080482.2 UniProtKB/TrEMBL
  ENSRNOT00000114063.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro ATG16 UniProtKB/TrEMBL
  Autophagy-rel_prot_16 UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep_reg UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:363278 UniProtKB/TrEMBL
NCBI Gene 363278 ENTREZGENE
PANTHER AUTOPHAGY-RELATED PROTEIN 16-1 UniProtKB/TrEMBL
  PTHR19878 UniProtKB/TrEMBL
Pfam ATG16 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Atg16l1 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017913 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A0G2K9U6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLZ1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZFK6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-24 Atg16l1  autophagy related 16-like 1  Atg16l1  autophagy related 16-like 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-06-07 Atg16l1  autophagy related 16-like 1 (S. cerevisiae)  Atg16l1  ATG16 autophagy related 16-like 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Atg16l1  ATG16 autophagy related 16-like 1 (S. cerevisiae)  Atg16l1  autophagy-related 16-like 1 (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Atg16l1  autophagy-related 16-like 1 (yeast)  Atg16l1_predicted  ATG16 autophagy related 16-like 1 (S. cerevisiae) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Atg16l1_predicted  ATG16 autophagy related 16-like 1 (S. cerevisiae) (predicted)  Apg16l_predicted  APG16 autophagy 16-like (S. cerevisiae) (predicted)  Symbol and Name updated 1299863 APPROVED