Tti2 (TELO2 interacting protein 2)

Gene: Tti2 (TELO2 interacting protein 2) Rattus norvegicus

Analyze

Symbol:

Tti2

Name:

TELO2 interacting protein 2

RGD ID:

1310414

Description:

Predicted to be part of TTT Hsp90 cochaperone complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 39. Orthologous to human TTI2 (TELO2 interacting protein 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; cadmium dichloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical protein LOC290811; LOC290811; RGD1310414; similar to hypothetical protein FLJ23263; Tel2 interacting protein 2; Tel2 interacting protein 2 homolog; Tel2 interacting protein 2 homolog (S. pombe); TELO2-interacting protein 2; uncharacterized protein C8orf41 homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TTI2 (TELO2 interacting protein 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Tti2 (TELO2 interacting protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tti2 (TELO2 interacting protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TTI2 (TELO2 interacting protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TTI2 (TELO2 interacting protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tti2 (TELO2 interacting protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TTI2 (TELO2 interacting protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TTI2 (TELO2 interacting protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tti2 (TELO2 interacting protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	JAKMIP1 (janus kinase and microtubule interacting protein 1)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Tti2 (TELO2 interacting protein 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TTI2 (TELO2 interacting protein 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tti2 (TELO2 interacting protein 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tti2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	67,683,721 - 67,692,881 (-)	NCBI		GRCr8
mRatBN7.2	16	60,980,665 - 60,988,587 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	60,979,039 - 60,988,569 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	66,296,140 - 66,304,013 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	69,710,646 - 69,718,519 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	64,937,114 - 64,944,940 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	64,737,342 - 64,745,207 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	64,737,340 - 64,745,207 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	64,394,792 - 64,402,657 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	64,888,131 - 64,895,996 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	64,888,205 - 64,896,071 (-)	NCBI
Celera	16	58,985,407 - 58,993,272 (-)	NCBI		Celera
Cytogenetic Map	16	q12.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive intellectual developmental disorder 39 (ISO)

genetic disease (ISO)

intellectual disability (ISO)

microcephaly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-hydroxypropanoic acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

decabromodiphenyl ether (EXP)

doxorubicin (ISO)

fenvalerate (EXP)

fulvestrant (ISO)

Methylazoxymethanol acetate (EXP)

monosodium L-glutamate (ISO)

perfluorooctane-1-sulfonic acid (ISO)

rac-lactic acid (ISO)

sodium arsenite (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytosol (IEA)

nucleus (IEA)

TTT Hsp90 cochaperone complex (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:35377872

Genomics

Comparative Map Data

Tti2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	67,683,721 - 67,692,881 (-)	NCBI		GRCr8
mRatBN7.2	16	60,980,665 - 60,988,587 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	60,979,039 - 60,988,569 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	66,296,140 - 66,304,013 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	69,710,646 - 69,718,519 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	64,937,114 - 64,944,940 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	64,737,342 - 64,745,207 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	64,737,340 - 64,745,207 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	64,394,792 - 64,402,657 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	64,888,131 - 64,895,996 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	64,888,205 - 64,896,071 (-)	NCBI
Celera	16	58,985,407 - 58,993,272 (-)	NCBI		Celera
Cytogenetic Map	16	q12.3	NCBI

TTI2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	33,498,722 - 33,513,135 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	33,473,386 - 33,513,185 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	33,356,240 - 33,370,653 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	33,475,775 - 33,490,245 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	32,305,939 - 32,320,408 (-)	NCBI		Celera
Cytogenetic Map	8	p12	NCBI
HuRef	8	31,888,081 - 31,902,749 (-)	NCBI		HuRef
CHM1_1	8	33,557,468 - 33,572,158 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	33,770,062 - 33,784,485 (-)	NCBI		T2T-CHM13v2.0

Tti2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	31,640,344 - 31,654,731 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	31,640,343 - 31,654,730 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	31,150,316 - 31,164,703 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	31,150,315 - 31,164,702 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	32,260,788 - 32,275,175 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	32,612,938 - 32,626,989 (+)	NCBI		MGSCv36	mm8
Celera	8	32,675,816 - 32,689,769 (+)	NCBI		Celera
Cytogenetic Map	8	A3	NCBI
cM Map	8	18.03	NCBI

Tti2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	9,652,321 - 9,660,739 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	9,652,226 - 9,660,712 (-)	NCBI	ChiLan1.0	ChiLan1.0

TTI2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	52,073,956 - 52,088,135 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	27,789,252 - 27,803,786 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	32,813,830 - 32,828,134 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	30,000,487 - 30,014,742 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	30,000,487 - 30,014,742 (-)	Ensembl	panpan1.1		panPan2

TTI2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	31,160,666 - 31,169,576 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	31,160,894 - 31,167,749 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	31,685,785 - 31,692,922 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	33,188,068 - 33,196,955 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	33,188,385 - 33,202,688 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	31,284,224 - 31,293,118 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	31,863,304 - 31,870,474 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	31,902,111 - 31,911,013 (+)	NCBI		UU_Cfam_GSD_1.0

Tti2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	54,156,205 - 54,165,580 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936766	415,884 - 429,928 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936766	416,372 - 425,844 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TTI2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	15	59,534,435 - 59,547,568 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TTI2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	31,584,395 - 31,598,311 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	31,575,943 - 31,598,387 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	10,454,049 - 10,471,671 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tti2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624780	10,429,942 - 10,438,635 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624780	10,429,783 - 10,441,051 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tti2
89 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	89
Count of miRNA genes:	79
Interacting mature miRNAs:	83
Transcripts:	ENSRNOT00000032467
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	19004435	75226532	Rat
2302057	Pia29	Pristane induced arthritis QTL 29	3.6	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	16	21735975	66735975	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	24325513	69325513	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	25152793	70152793	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	35288870	80288870	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	37752156	82752156	Rat
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	37752156	82752156	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	42396345	84729064	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	52726464	84729064	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	52726464	84729064	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	52726464	84729064	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	55711087	83402471	Rat

Markers in Region

RH137645

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	60,983,016 - 60,983,216 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	64,739,694 - 64,739,893	NCBI	Rnor6.0
Rnor_5.0	16	64,397,144 - 64,397,343	UniSTS	Rnor5.0
RGSC_v3.4	16	64,890,483 - 64,890,682	UniSTS	RGSC3.4
Celera	16	58,987,759 - 58,987,958	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

RH142490

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	60,980,967 - 60,981,078 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	64,737,645 - 64,737,755	NCBI	Rnor6.0
Rnor_5.0	16	64,395,095 - 64,395,205	UniSTS	Rnor5.0
RGSC_v3.4	16	64,888,434 - 64,888,544	UniSTS	RGSC3.4
Celera	16	58,985,710 - 58,985,820	UniSTS
RH 3.4 Map	16	567.01	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

AW527757

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	60,984,230 - 60,984,381 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	64,740,908 - 64,741,058	NCBI	Rnor6.0
Rnor_5.0	16	64,398,358 - 64,398,508	UniSTS	Rnor5.0
RGSC_v3.4	16	64,891,697 - 64,891,847	UniSTS	RGSC3.4
Celera	16	58,988,973 - 58,989,123	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

RH135178

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	60,980,306 - 60,980,494 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	64,736,984 - 64,737,171	NCBI	Rnor6.0
Rnor_5.0	16	64,394,434 - 64,394,621	UniSTS	Rnor5.0
RGSC_v3.4	16	64,887,773 - 64,887,960	UniSTS	RGSC3.4
Celera	16	58,985,049 - 58,985,236	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

RH137307

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	60,980,753 - 60,982,063 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	64,737,431 - 64,738,740	NCBI	Rnor6.0
Rnor_5.0	16	64,394,881 - 64,396,190	UniSTS	Rnor5.0
RGSC_v3.4	16	64,888,220 - 64,889,529	UniSTS	RGSC3.4
Celera	16	58,985,496 - 58,986,805	UniSTS
RH 3.4 Map	16	570.1	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

BE099580

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	60,988,047 - 60,988,202 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	64,744,725 - 64,744,879	NCBI	Rnor6.0
Rnor_5.0	16	64,402,175 - 64,402,329	UniSTS	Rnor5.0
RGSC_v3.4	16	64,895,514 - 64,895,668	UniSTS	RGSC3.4
Celera	16	58,992,790 - 58,992,944	UniSTS
RH 3.4 Map	16	567.01	UniSTS
Cytogenetic Map	16	q12.3	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	14	15	6	18	6			74	23	41	11
Low	1	29	42	35	1	35	8	11		12			8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094394	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC082008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000032467 ⟹ ENSRNOP00000028965

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	60,980,668 - 60,988,569 (-)	Ensembl
Rnor_6.0 Ensembl	16	64,737,340 - 64,745,207 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000092922 ⟹ ENSRNOP00000075984

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	16	64,740,855 - 64,741,762 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000101366 ⟹ ENSRNOP00000093201

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	60,983,481 - 60,988,569 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000112783 ⟹ ENSRNOP00000090765

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	60,979,039 - 60,988,569 (-)	Ensembl

RefSeq Acc Id:

NM_001013883 ⟹ NP_001013905

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	67,683,723 - 67,691,588 (-)	NCBI
mRatBN7.2	16	60,980,665 - 60,988,530 (-)	NCBI
Rnor_6.0	16	64,737,342 - 64,745,207 (-)	NCBI
Rnor_5.0	16	64,394,792 - 64,402,657 (-)	NCBI
RGSC_v3.4	16	64,888,131 - 64,895,996 (-)	RGD
Celera	16	58,985,407 - 58,993,272 (-)	RGD

Sequence:

show sequence

AAAGCTGTAGGTGTCGGGAGCCTTTTTGGTGTCACAGTTCAGTAGGTTATCTTTAAAATTAACT
TGTTTTTGAGTCTCCAGAAAGACAAATTTCGCCACATGTTAGGAGGCCCCTTCTTACACCCACT
TAACCGAGTGGATTGACACTCGATCCTTGTGTCATAACAGTAAGCCTTTTCACTGTGCATGATT
TTAGATTTGTTCGTTGGGGTACTCCCGGCCCCGAACACCTCCCCTATTTGGTCTCTGACCCCGC
GGAGAGCCCAGCCCATCGGGTGAGACTAGGAATGAAGCTTGGCAGCACCGAAGAGAAGTCGGGG
GGCGGCTGCTCCCTGCCTACAGAGGTGTCTCCCCCGGCCCTCCAACAAGCCTTTTCCAAGATTC
TGCACGGTCTCAGCCGCCAAGAGTCATCAGGACAAGGCAACGCAGGAAATGCCGCTCTAAGAGA
CCTCGGTGCTTTAATAGAAGCCACCGAATGTGACAAATTATTTGAGGGGACTGGGGGTGGTGGA
TCCCCCCGGGAGATGCCCGAGATCCTGGGACAGGTGGCGAAAGCCCTGGAGAAGTTCGCAGCAC
CCAAGGAGAAGGCAGATGGAAGCGAAGAACATCCCGAAGTGCCCGAGAAGGCAACTGAGGTTGG
GTTACTATTTCTTAAGCTGTTGGGGAAGGTTGAAACTGCTAAGAGTTCTCCCGTCTGCCCTGCA
TGGAAGACAGGCCTCCGCCACTTGTCAGGACCCACGTATATTTTTGCCATCACACACAGATTGA
AGCAGCCATGGACCAGTCCGAAATCTCAGCATGTTGCTGGTGAGGTGCTGTCTTTACTGTTTCG
TGTTACTGAGTGCAGTTCTGTGGCAGAATTCCTATGCGGAGAAAACAAAGATGATCGGGGGAGA
TTCGCTGTGGTCTTGGGGCTTCTTAAGCCCCACTTGAATAAGGAAACCTGGAAGAAGAATCCTG
CTGTCAAACATGTTTTCTCATGGACTCTCCAACAAGTCACTCAGCCCTGGCTGAGCCAGCATCT
AGAAAAGATACTTCCCCCATCTTTGCTCATCTCAGATGATTATCAGACGGACAATAAGGTCCTG
GGTGTCCAGTGCCTCCATCACATTGTGATTAATGTGCCAGCCGCTGACCTGCTGCAGTACAACA
GAGCCCAGGTCCTGTACCATGCTCTTTTCAATCACCTGTACATGCCAGAGCACCGCCTCATTCA
GGCTGTGCTCCTGTGTCTCTTAGATTTATTCCCTGTCCTAGAGAAAGCGCTGCACTGGCAGGGA
GAAGCCGCTCGAGCCTCTACACACTGTCACGAGGTGCTACAACTGGTCCTCACGCACATGGAGT
CAGAGCACCGCCTTCTCCTCCGTAGGACTTACGCCAGGAACCTGCCGGCCTTTGTGAAGAAGTT
GGGGATCCTAACCGCCCGGCACTTGAAGAGGCTGGAGCAAGTTATCCTTGGTTACCTGGAGGTT
TATGATGAACCGGAAGATGAAAGCAGGCTGAAGATACTGGAAACCCTGAAACTTGTCATGCAGT
ACACTTGGCCCAGAATTCCCTGCAGAGTTGTGGTCTTACTGAAGGCTCTCCTGAAACTGATATG
TGATATAGCCAGGGACACGATCCCCACAACTGAGGCTGCTAAGAGTGCGGTGCTCCAGGAAGCC
ACAGACTGCCTGATTCTCCTGGACCACTGTTCTCAGGGGCAGGTGAAGGGTCTTCTGGCTAACA
TCGCCCTGTCCTGTGACGACAGCACAGTGGTGAGCTGCATCAGGAAGGTGCAGGGCTCTGCAGA
GGCTCCCGGCGAGGACCCTGGAGATGACTAACCAGCAGGAAAGACTGCTCTTCTTACCCCGTTC
ATATGGACGGACTCATGGGCATTTAAAAAAAATCTATTTTTGTATTAAAATATAAGTTGAAATT
TAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039094394 ⟹ XP_038950322

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	67,683,721 - 67,692,881 (-)	NCBI
mRatBN7.2	16	60,980,665 - 60,988,587 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013905	(Get FASTA)	NCBI Sequence Viewer
	XP_038950322	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH82008	(Get FASTA)	NCBI Sequence Viewer
	EDM09112	(Get FASTA)	NCBI Sequence Viewer
	EDM09113	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000028965
	ENSRNOP00000028965.3
	ENSRNOP00000090765.1
	ENSRNOP00000093201.1
GenBank Protein	Q66H56	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013905 ⟸ NM_001013883

- UniProtKB:

Q66H56 (UniProtKB/Swiss-Prot), A6IVV9 (UniProtKB/TrEMBL), A0A8I6GII0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKLGSTEEKSGGGCSLPTEVSPPALQQAFSKILHGLSRQESSGQGNAGNAALRDLGALIEATEC
DKLFEGTGGGGSPREMPEILGQVAKALEKFAAPKEKADGSEEHPEVPEKATEVGLLFLKLLGKV
ETAKSSPVCPAWKTGLRHLSGPTYIFAITHRLKQPWTSPKSQHVAGEVLSLLFRVTECSSVAEF
LCGENKDDRGRFAVVLGLLKPHLNKETWKKNPAVKHVFSWTLQQVTQPWLSQHLEKILPPSLLI
SDDYQTDNKVLGVQCLHHIVINVPAADLLQYNRAQVLYHALFNHLYMPEHRLIQAVLLCLLDLF
PVLEKALHWQGEAARASTHCHEVLQLVLTHMESEHRLLLRRTYARNLPAFVKKLGILTARHLKR
LEQVILGYLEVYDEPEDESRLKILETLKLVMQYTWPRIPCRVVVLLKALLKLICDIARDTIPTT
EAAKSAVLQEATDCLILLDHCSQGQVKGLLANIALSCDDSTVVSCIRKVQGSAEAPGEDPGDD

hide sequence

RefSeq Acc Id:

ENSRNOP00000075984 ⟸ ENSRNOT00000092922

RefSeq Acc Id:

ENSRNOP00000028965 ⟸ ENSRNOT00000032467

RefSeq Acc Id:	XP_038950322 ⟸ XM_039094394
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000093201 ⟸ ENSRNOT00000101366

RefSeq Acc Id:

ENSRNOP00000090765 ⟸ ENSRNOT00000112783

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q66H56-F1-model_v2	AlphaFold	Q66H56	1-511	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700148

Promoter ID:

EPDNEW_R10671

Type:

multiple initiation site

Name:

Tti2_1

Description:

TELO2 interacting protein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	64,745,248 - 64,745,308	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310414	AgrOrtholog
BioCyc Gene	G2FUF-11088	BioCyc
Ensembl Genes	ENSRNOG00000023494	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000032467	ENTREZGENE
	ENSRNOT00000032467.5	UniProtKB/Swiss-Prot
	ENSRNOT00000101366.1	UniProtKB/TrEMBL
	ENSRNOT00000112783.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7131694	IMAGE-MGC_LOAD
InterPro	ARM-type_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tti2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:290811	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:94257	IMAGE-MGC_LOAD
NCBI Gene	290811	ENTREZGENE
PANTHER	PTHR32226	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TELO2-INTERACTING PROTEIN 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Tti2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Tti2	PhenoGen
RatGTEx	ENSRNOG00000023494	RatGTEx
Superfamily-SCOP	SSF48371	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6GII0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GKJ9_RAT	UniProtKB/TrEMBL
	A6IVV9	ENTREZGENE, UniProtKB/TrEMBL
	Q66H56	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-12-06	Tti2	TELO2 interacting protein 2	Tti2	Tel2 interacting protein 2 homolog (S. pombe)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-09-29	Tti2	Tel2 interacting protein 2 homolog (S. pombe)	RGD1310414	similar to hypothetical protein FLJ23263	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1310414	similar to hypothetical protein FLJ23263	RGD1310414_predicted	similar to hypothetical protein FLJ23263 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1310414_predicted	similar to hypothetical protein FLJ23263 (predicted)	LOC290811_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC290811_predicted	similar to hypothetical protein FLJ23263 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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