Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of TMEM177 mRNA | CTD | PMID:23649840 | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | TMEM177 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TMEM177 mRNA | CTD | PMID:22079256 | 1,2-dichloroethane | decreases expression | ISO | Tmem177 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TMEM177 mRNA | CTD | PMID:28960355 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tmem177 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM177 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TMEM177 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM177 mRNA | CTD | PMID:32277265 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Tmem177 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of TMEM177 mRNA | CTD | PMID:28973697 | acrylamide | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of TMEM177 mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | ISO | TMEM177 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TMEM177 intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of TMEM177 mRNA | CTD | PMID:33167477 | antirheumatic drug | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TMEM177 mRNA | CTD | PMID:24449571 | arsenous acid | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of TMEM177 mRNA | CTD | PMID:24356939 | benzo[a]pyrene | increases methylation | ISO | TMEM177 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TMEM177 promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TMEM177 mRNA | CTD | PMID:34947998 | carbon nanotube | decreases expression | ISO | Tmem177 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of TMEM177 mRNA | CTD | PMID:25554681 | chlorpyrifos | increases expression | ISO | Tmem177 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TMEM177 mRNA | CTD | PMID:37019170 | chromium(6+) | affects expression | ISO | TMEM177 (Homo sapiens) | 6480464 | chromium hexavalent ion affects the expression of TMEM177 mRNA | CTD | PMID:30690063 | cobalt dichloride | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of TMEM177 mRNA | CTD | PMID:19376846 | copper atom | multiple interactions | ISO | TMEM177 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TMEM177 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | TMEM177 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TMEM177 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of TMEM177 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TMEM177 mRNA | CTD | PMID:20106945 more ... | diarsenic trioxide | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of TMEM177 mRNA | CTD | PMID:24356939 | ethyl methanesulfonate | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of TMEM177 mRNA | CTD | PMID:23649840 | formaldehyde | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of TMEM177 mRNA | CTD | PMID:20655997 and PMID:23649840 | gamma-hexachlorocyclohexane | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Hexachlorocyclohexane results in decreased expression of TMEM177 mRNA | CTD | PMID:24356939 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of TMEM177 mRNA | CTD | PMID:33387578 | menadione | affects expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of TMEM177 mRNA | CTD | PMID:20044591 | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of TMEM177 mRNA | CTD | PMID:19564919 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of TMEM177 gene | CTD | PMID:35440735 | methyl methanesulfonate | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of TMEM177 mRNA | CTD | PMID:23649840 | ochratoxin A | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | ochratoxin A metabolite results in decreased expression of TMEM177 mRNA and ochratoxin A results in decreased expression of TMEM177 mRNA | CTD | PMID:24356939 | paracetamol | affects expression | ISO | Tmem177 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TMEM177 mRNA | CTD | PMID:17562736 | paracetamol | affects response to substance | ISO | TMEM177 (Homo sapiens) | 6480464 | TMEM177 gene polymorphism affects the susceptibility to Acetaminophen | CTD | PMID:26104854 | perfluorooctanoic acid | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of TMEM177 mRNA | CTD | PMID:36326898 | pioglitazone | multiple interactions | ISO | TMEM177 (Homo sapiens) | 6480464 | [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of TMEM177 mRNA | CTD | PMID:20847119 | potassium chloride | multiple interactions | ISO | TMEM177 (Homo sapiens) | 6480464 | [Dronabinol results in decreased susceptibility to Potassium Chloride] which results in decreased expression of TMEM177 mRNA | CTD | PMID:29691375 | potassium chromate | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of TMEM177 mRNA | CTD | PMID:22079256 | potassium chromate | increases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of TMEM177 mRNA | CTD | PMID:22714537 | potassium chromate | multiple interactions | ISO | TMEM177 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TMEM177 mRNA | CTD | PMID:22079256 | silver atom | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Silver results in decreased expression of TMEM177 mRNA | CTD | PMID:26014281 | silver(0) | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Silver results in decreased expression of TMEM177 mRNA | CTD | PMID:26014281 | sodium dodecyl sulfate | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in decreased expression of TMEM177 mRNA | CTD | PMID:31734321 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of TMEM177 mRNA | CTD | PMID:19281266 | temozolomide | increases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of TMEM177 mRNA | CTD | PMID:31758290 | tert-butyl hydroperoxide | multiple interactions | ISO | TMEM177 (Homo sapiens) | 6480464 | [pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of TMEM177 mRNA more ... | CTD | PMID:20847119 | tert-butyl hydroperoxide | increases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of TMEM177 mRNA | CTD | PMID:15336504 | tert-butyl hydroperoxide | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of TMEM177 mRNA | CTD | PMID:20847119 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TMEM177 mRNA | CTD | PMID:34492290 | troglitazone | multiple interactions | ISO | TMEM177 (Homo sapiens) | 6480464 | [troglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of TMEM177 mRNA and troglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of TMEM177 mRNA] | CTD | PMID:20847119 | tunicamycin | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of TMEM177 mRNA | CTD | PMID:22378314 | urethane | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Urethane results in decreased expression of TMEM177 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TMEM177 mRNA | CTD | PMID:28001369 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of TMEM177 mRNA | CTD | PMID:23034163 | vincristine | decreases expression | ISO | TMEM177 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of TMEM177 mRNA | CTD | PMID:23649840 | |