Misp3 (MISP family member 3) - Rat Genome Database

Name: Misp3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Misp3 (MISP family member 3) Rattus norvegicus

Analyze

Symbol:

Misp3

Name:

MISP family member 3

RGD ID:

1310262

Description:

Orthologous to human MISP3 (MISP family member 3); INTERACTS WITH 6-propyl-2-thiouracil; 7,12-dimethyltetraphene; benzo[a]pyrene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical LOC304650; hypothetical protein LOC304650; LOC304650; RGD1310262; uncharacterized protein LOC304650; uncharacterized protein MISP3

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MISP3 (MISP family member 3)	HGNC	EggNOG, Ensembl, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Misp3 (MISP family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Misp3 (MISP family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MISP3 (MISP family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MISP3 (MISP family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MISP3 (MISP family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MISP3 (MISP family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Misp3 (MISP family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Misp3 (MISP family member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MISP3 (MISP family member 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-207j7.2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	si:ch211-262i1.3	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	misp3	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	41,043,408 - 41,046,761 (+)	NCBI		GRCr8
mRatBN7.2	19	24,139,998 - 24,142,006 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	24,140,033 - 24,142,631 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	30,961,157 - 30,963,118 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	31,615,563 - 31,617,524 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	33,838,285 - 33,840,246 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	25,132,089 - 25,135,041 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	25,132,094 - 25,134,055 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	36,108,972 - 36,112,288 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	25,826,018 - 25,827,979 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	25,830,531 - 25,832,602 (+)	NCBI
Celera	19	23,687,736 - 23,689,697 (+)	NCBI		Celera
Cytogenetic Map	19	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

6-propyl-2-thiouracil (EXP,ISO)

7,12-dimethyltetraphene (EXP)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP)

chlorpyrifos (ISO)

cisplatin (ISO)

diiodine (ISO)

indole-3-methanol (EXP)

leflunomide (ISO)

mono(2-ethylhexyl) phthalate (ISO)

paraquat (EXP)

trichloroethene (EXP)

triptonide (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Misp3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	41,043,408 - 41,046,761 (+)	NCBI		GRCr8
mRatBN7.2	19	24,139,998 - 24,142,006 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	24,140,033 - 24,142,631 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	30,961,157 - 30,963,118 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	31,615,563 - 31,617,524 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	33,838,285 - 33,840,246 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	25,132,089 - 25,135,041 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	25,132,094 - 25,134,055 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	36,108,972 - 36,112,288 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	25,826,018 - 25,827,979 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	25,830,531 - 25,832,602 (+)	NCBI
Celera	19	23,687,736 - 23,689,697 (+)	NCBI		Celera
Cytogenetic Map	19	q11	NCBI

MISP3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	14,072,786 - 14,075,062 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	14,072,536 - 14,075,062 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	14,183,598 - 14,185,874 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	14,044,348 - 14,046,875 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	14,077,623 - 14,079,676 (+)	NCBI		Celera
Cytogenetic Map	19	p13.12	NCBI
HuRef	19	13,755,479 - 13,757,532 (+)	NCBI		HuRef
CHM1_1	19	14,184,392 - 14,186,445 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	14,199,078 - 14,201,354 (+)	NCBI		T2T-CHM13v2.0

Misp3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	84,736,857 - 84,738,349 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	84,736,851 - 84,738,800 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	84,010,228 - 84,011,720 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	84,010,222 - 84,012,171 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	86,534,127 - 86,536,055 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	86,900,333 - 86,902,261 (-)	NCBI		MGSCv36	mm8
Celera	8	88,303,363 - 88,305,291 (-)	NCBI		Celera
Cytogenetic Map	8	C2	NCBI
cM Map	8	40.24	NCBI

Misp3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955415	32,777,456 - 32,780,734 (+)	NCBI	ChiLan1.0	ChiLan1.0

MISP3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	19,004,760 - 19,007,213 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	18,007,119 - 18,008,888 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	13,638,125 - 13,640,403 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	14,364,583 - 14,367,440 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

MISP3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ROS_Cfam_1.0	20	48,957,022 - 48,960,645 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	48,957,367 - 48,958,818 (-)	Ensembl		ROS_Cfam_1.0 Ensembl

MISP3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	65,107,408 - 65,110,222 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	65,107,742 - 65,110,085 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	65,381,889 - 65,384,215 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MISP3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	12,714,003 - 12,717,317 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666074	6,931,305 - 6,933,636 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Misp3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624901	1,304,720 - 1,307,606 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624901	1,304,754 - 1,306,999 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Misp3
3 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	50
Count of miRNA genes:	45
Interacting mature miRNAs:	49
Transcripts:	ENSRNOT00000007519
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411590	Foco7	Food consumption QTL 7	6.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	19	1	24688055	Rat
10054132	Srcrt9	Stress Responsive Cort QTL 9	2.87	0.0017	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	1	27355345	Rat
631678	Cm9	Cardiac mass QTL 9	4.27	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	19	1	28982497	Rat
631681	Cm12	Cardiac mass QTL 12	3.33	0.00053	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	19	1	28982497	Rat
1549847	Bss8	Bone structure and strength QTL 8	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	19	1	31963836	Rat
9590298	Uminl5	Urine mineral level QTL 5	3.59	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	19	1	36824771	Rat
8552935	Pigfal10	Plasma insulin-like growth factor 1 level QTL 10	5.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	19	1	36824771	Rat
9590250	Scort11	Serum corticosterone level QTL 11	23.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	1	36824771	Rat
9590090	Insglur8	Insulin/glucose ratio QTL 8	10.81	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	19	1	36824771	Rat
9589102	Slep13	Serum leptin concentration QTL 13	4.63	0.001	blood leptin amount (VT:0005667)	plasma leptin level (CMO:0000781)	19	569374	45569374	Rat
8694186	Bw152	Body weight QTL 152	3.34	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	569374	45569374	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2187927	46708701	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2187927	56457239	Rat
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	2316121	47316121	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	3204777	48204777	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	4096155	55283277	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	7457249	42983518	Rat
724565	Tcas5	Tongue tumor susceptibility QTL 5	10.04		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	19	9977753	39654489	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10827970	43544039	Rat
61407	Scl12	Serum cholesterol level QTL 12		0.001	blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	19	13926401	30303727	Rat
1558656	Prcs1	Prostate cancer susceptibility QTL 1	5		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	19	15114598	34521833	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	15455860	57337602	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	15605023	46559041	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	15630201	57337602	Rat
2298478	Eau8	Experimental allergic uveoretinitis QTL 8		0.0163	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	19	17154433	57337602	Rat
61350	Bp32	Blood pressure QTL 32		0.012	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	19	20483575	57337602	Rat

Markers in Region

RH131676

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	24,141,727 - 24,141,910 (-)	MAPPER	mRatBN7.2
Rnor_6.0	19	25,132,178 - 25,132,360	NCBI	Rnor6.0
Rnor_5.0	19	36,109,056 - 36,109,238	UniSTS	Rnor5.0
RGSC_v3.4	19	25,827,713 - 25,827,895	UniSTS	RGSC3.4
Celera	19	23,689,431 - 23,689,613	UniSTS
Cytogenetic Map	19	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium										11	7	10
Low	3	14					5	7	27	20	22	1	5
Below cutoff		25	16	8	18	8	3	4	25	4	10		3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000007519 ⟹ ENSRNOP00000007519

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	24,140,033 - 24,141,994 (+)	Ensembl
Rnor_6.0 Ensembl	19	25,132,094 - 25,134,055 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094433 ⟹ ENSRNOP00000081833

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	24,140,069 - 24,142,631 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000112316 ⟹ ENSRNOP00000091192

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	24,140,061 - 24,142,008 (+)	Ensembl

RefSeq Acc Id:

NM_001107161 ⟹ NP_001100631

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	41,044,795 - 41,046,756 (+)	NCBI
mRatBN7.2	19	24,140,033 - 24,141,994 (+)	NCBI
Rnor_6.0	19	25,132,094 - 25,134,055 (-)	NCBI
Rnor_5.0	19	36,108,972 - 36,112,288 (-)	NCBI
RGSC_v3.4	19	25,826,018 - 25,827,979 (+)	RGD
Celera	19	23,687,736 - 23,689,697 (+)	RGD

Sequence:

show sequence

GGGTCAAAGAAGAGTGCTGGCGACGCCTTAGAACCTCGGGCGGCGGCTGCAACCACAGTTGTGC
CCCTGCGTCGGCTCAGAGGCCTCCAGGTGTGTTTTCCACCGAGGCCCGTGGCATCCAAACCAGC
GCCTGCGGAACTGCTGATGGAGACGCCCATCCAGCGCGAAATCCGCCGTAGCTGCGAGCGCGAG
GAGAGCCTGCGCCGGAGCCGCGGTCTGAGTCCGGGTCGCGCGGGAGAGGAACTCATCGAGTTGC
GGGTGCGGCCGGTGCTCAGCCGGCCAGGTTCCGGTATCCCGCTGCCGCGCGCCCTGGAGCGCGC
TCGGGCGGGCGCGAAGATGCAACGGGACATCGAACGCGAGGCTCACAGGCAGGCGGCGCTGGCG
AGCCCCGCGGTTCCGGAGCCCAGCGCCCGGCCGCGGCCGCAGCCGCTGGATGAACTCAAGCGCT
TCTTTGAGGCTGCGGCAGAGGACGGAGCGAGCTTGCAGCGGCAGCCGGAGGCCGGAGGCCGGTT
GCACCCCGCCCTTCAGGACGGCTGTCCGGTACTGGGGCAGTTGCCGCCGCTCGTTGCTCCGTCA
CTGCTAGAGCAGGAGGTGCTCCGGGTGCGTGAGCGCGAGCGGGAGCTGCAGCTGCAGCGGCGCA
GCATCTACGGGGCAGCCGAGGACCGGGAGCCAGCGCCGAGCCTCACCCAGAGCAGGGGAGATGG
AAAGTTGGCGGTGACCTGGCCCCCGCGGAGACAGGCCTCAGAGAACGGCCTGGAGAAGGAGCGC
AGACCCTGAGGTCTGTGAAGGTTGGGGCCTGCGGCCAGAAGTAACATGCCCTTTGGAGAACCAG
GGTAGGGTTATCCTCCAGATCAGCAGAAGGCCTAGAGAGGGAAGGCCCAGCTTTCTTTAATGGA
AACTTGAAATTCAGCCCATCCCTGATACTGACTATGGAATTAACCACCTCTCTCCATAAAAGTG
TTTAGTCTTCCCTGGAAAATAGACCACCGCCCGCAAAACCTGAGTGAAACATACAATAAAGTTC
TCCTCCCTTTTC

hide sequence

RefSeq Acc Id:

XM_006255249 ⟹ XP_006255311

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	41,043,408 - 41,046,761 (+)	NCBI
mRatBN7.2	19	24,140,024 - 24,142,006 (+)	NCBI
Rnor_6.0	19	25,132,089 - 25,135,027 (-)	NCBI
Rnor_5.0	19	36,108,972 - 36,112,288 (-)	NCBI

Sequence:

show sequence

ACCCTTATTCCTCTTTCCATTTTCTTTAGGTAATTGTCTTTCTCCCAGGTTACTATAGAATGAC
ACGGGGTGGGCCGGTTTTTGTGAAAGTTGTCTTCCACAAGGGGCAGTGGAAAAAGTTTCTGCCC
TCACTCTGAACCCTTGACCCTATCCTGGAAGACAACGGAGCAGCAAAGGTCGCTACTGCCTCCC
GCGAACCCCGTATCTCTTCTGCCCCAGCCTGGGCCTCCTAAGCAACCTGGCCCAAGCTGACCGT
CTTCCGTCCGCAATTGCTCATCTAGGGCCCGGAAGTCTTGTAGTGCCTGGGCTCTCAACCCTCG
CTCATTCTAGCTGGACACTTGGCTGCCAACGCCTTGTGGGCTTTTTTGGAAGGTGGTGGTGCTG
GGGGAGCTGCTCCAGGGCTTTGAGCGGCAGCAGTGGGGCTGCAAACCCAGGCAGAGCTAAGCAA
CCCAGAGCAGCAGGAGCAGGCATTGGGGTGCCCCCGGGTGCCCCCACGGGCTGAACCCGAGCTG
TGCTGCAGCAGCGATTTGTGTGCAGAGAAGACCGGGAGACCACAGGGGGGGTAAGGGGGGCCAT
GTCGCTGGCCGCGGGCTGGCACCTGCTGAGCTAGACTAGTGAGGTCAGCGAAAGACGACCGGGG
AAACACTCTGTAAGGAGGCCATGGACAGCGATCAGCACGGCGCTCCACTAGAGGTCAGATCTCC
AGAAAGTGATAAAAAAACGAGACCCCAAAAATGCCAGCGTGGTACCAGAGGGAAAGGGCGACAC
ATACCCCCTTGGGTAGAGTTCAGGGAAGCCCTTTCTGAAGAAAACGTCCCTTCAGTCAACCCGT
GGGTTCAGGTGGCGGGAATCCGGCGTCCAGCCTAGGCGCCCTGGCCATAGGGCGGGTCCAGGGC
CACTGGAATCCAGCTGGCAGGTGCCGGGGGCGGTGCCCAGTCCTGCCCCCAGGGGACCTTCCTG
GAGGCCAGAGGCGGGTCAAAGAAGAGTGCTGGCGACGCCTTAGAACCTCGGGCGGCGGCTGCAA
CCACAGGTACGGCGCAGGGCATTGTGTCCTACCTATCTGGGCATCTTAATCCGGCTCTGAGAAC
TGAAATTGTCAAAGTGCGCCTAACTCCGAACATCCATGCCCCCGGGTGTCCGAGAGCGGAGTCC
TGGGATCGCCTGAAACTTAAAGCTACGTGTTCCGGGAGCCGCAGAGCCAGGGCACCGAGGGCTG
CAGGGGGAGGTAGTGAGGTCCTGAAAACCTCTGGAGAGGAGGACTTGGAGACCCCGGGGCCATA
GCCAGGTCCCGCAAGTGCCAGTGGAGCAGGTGACTGAGCGCCCGGGCGGTCCGCGTCTGGGTCG
CCTGGCACTTGGATAACGGAGGTACTGGGACAGTTGTGCCCCTGCGTCGGCTCAGAGGCCTCCA
GGTGTGTTTTCCACCGAGGCCCGTGGCATCCAAACCAGCGCCTGCGGAACTGCTGATGGAGACG
CCCATCCAGCGCGAAATCCGCCGTAGCTGCGAGCGCGAGGAGAGCCTGCGCCGGAGCCGCGGTC
TGAGTCCGGGTCGCGCGGGAGAGGAACTCATCGAGTTGCGGGTGCGGCCGGTGCTCAGCCGGCC
AGGTTCCGGTATCCCGCTGCCGCGCGCCCTGGAGCGCGCTCGGGCGGGCGCGAAGATGCAACGG
GACATCGAACGCGAGGCTCACAGGCAGGCGGCGCTGGCGAGCCCCGCGGTTCCGGAGCCCAGCG
CCCGGCCGCGGCCGCAGCCGCTGGATGAACTCAAGCGCTTCTTTGAGGCTGCGGCAGAGGACGG
AGCGAGCTTGCAGCGGCAGCCGGAGGCCGGAGGCCGGTTGCACCCCGCCCTTCAGGACGGCTGT
CCGGTACTGGGGCAGTTGCCGCCGCTCGTTGCTCCGTCACTGCTAGAGCAGGAGGTGCTCCGGG
TGCGTGAGCGCGAGCGGGAGCTGCAGCTGCAGCGGCGCAGCATCTACGGGGCAGCCGAGGACCG
GGAGCCAGCGCCGAGCCTCACCCAGAGCAGGGGAGATGGAAAGTTGGCGGTGACCTGGCCCCCG
CGGAGACAGGCCTCAGAGAACGGCCTGGAGAAGGAGCGCAGACCCTGAGGTCTGTGAAGGTTGG
GGCCTGCGGCCAGAAGTAACATGCCCTTTGGAGAACCAGGGTAGGGTTATCCTCCAGATCAGCA
GAAGGCCTAGAGAGGGAAGGCCCAGCTTTCTTTAATGGAAACTTGAAATTCAGCCCATCCCTGA
TACTGACTATGGAATTAACCACCTCTCTCCATAAAAGTGTTTAGTCTTCCCTGGAAAATAGACC
ACCGCCCGCAAAACCTGAGTGAAACATACAATAAAGTTCTCCTCCCTTTTCCTGGG

hide sequence

RefSeq Acc Id:

XM_017601253 ⟹ XP_017456742

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	41,043,408 - 41,046,556 (+)	NCBI
mRatBN7.2	19	24,139,998 - 24,142,006 (+)	NCBI
Rnor_6.0	19	25,132,089 - 25,135,041 (-)	NCBI

Sequence:

show sequence

AGGCTTGTGCCTCCACCCTTATTCCTCTTTCCATTTTCTTTAGGTAATTGTCTTTCTCCCAGGT
TACTATAGAATGACACGGGGTGGGCCGGTTTTTGTGAAAGTTGTCTTCCACAAGGGGCAGTGGA
AAAAGTTTCTGCCCTCACTCTGAACCCTTGACCCTATCCTGGAAGACAACGGAGCAGCAAAGGT
CGCTACTGCCTCCCGCGAACCCCGTATCTCTTCTGCCCCAGCCTGGGCCTCCTAAGCAACCTGG
CCCAAGCTGACCGTCTTCCGTCCGCAATTGCTCATCTAGGGCCCGGAAGTCTTGTAGTGCCTGG
GCTCTCAACCCTCGCTCATTCTAGCTGGACACTTGGCTGCCAACGCCTTGTGGGCTTTTTTGGA
AGGTGGTGGTGCTGGGGGAGCTGCTCCAGGGCTTTGAGCGGCAGCAGTGGGGCTGCAAACCCAG
GCAGAGCTAAGCAACCCAGAGCAGCAGGAGCAGGCATTGGGGTGCCCCCGGGTGCCCCCACGGG
CTGAACCCGAGCTGTGCTGCAGCAGCGATTTGTGTGCAGAGAAGACCGGGAGACCACAGGGGGG
GTAAGGGGGGCCATGTCGCTGGCCGCGGGCTGGCACCTGCTGAGCTAGACTAGTGAGGTCAGCG
AAAGACGACCGGGGAAACACTCTGTAAGGAGGCCATGGACAGCGATCAGCACGGCGCTCCACTA
GAGGTCAGATCTCCAGAAAGTGATAAAAAAACGAGACCCCAAAAATGCCAGCGTGGTACCAGAG
GGAAAGGGCGACACATACCCCCTTGGGTAGAGTTCAGGGAAGCCCTTTCTGAAGAAAACGTCCC
TTCAGTCAACCCGTGGGTTCAGGTGGCGGGAATCCGGCGTCCAGCCTAGGCGCCCTGGCCATAG
GGCGGGTCCAGGGCCACTGGAATCCAGCTGGCAGGTGCCGGGGGCGGTGCCCAGTCCTGCCCCC
AGGGGACCTTCCTGGAGGCCAGAGGCGGGTCAAAGAAGAGTGCTGGCGACGCCTTAGAACCTCG
GGCGGCGGCTGCAACCACAGGTACGGCGCAGGGCATTGTGTCCTACCTATCTGGGCATCTTAAT
CCGGCTCTGAGAACTGAAATTGTCAAAGTGCGCCTAACTCCGAACATCCATGCCCCCGGGTGTC
CGAGAGCGGAGTCCTGGGATCGCCTGAAACTTAAAGCTACGTGTTCCGGGAGCCGCAGAGCCAG
GGCACCGAGGGCTGCAGGGGGAGGTAGTGAGGTCCTGAAAACCTCTGGAGAGGAGGACTTGGAG
ACCCCGGGGCCATAGCCAGGTCCCGCAAGTGCCAGTGGAGCAGGTGACTGAGCGCCCGGGCGGT
CCGCGTCTGGGTCGCCTGGCACTTGGATAACGGAGGTACTGGGACAGTTGTGCCCCTGCGTCGG
CTCAGAGGCCTCCAGGTGTGTTTTCCACCGAGGCCCGTGGCATCCAAACCAGCGCCTGCGGAAC
TGCTGATGGAGACGCCCATCCAGCGCGAAATCCGCCGTAGCTGCGAGCGCGAGGAGAGCCTGCG
CCGGAGCCGCGGTCTGAGTCCGGGTCGCGCGGGAGAGGAACTCATCGAGTTGCGGGTGCGGCCG
GTGCTCAGCCGGCCAGGTTCCGGTATCCCGCTGCCGCGCGCCCTGGAGCGCGCTCGGGCGGGCG
CGAAGATGCAACGGGACATCGAACGCGAGGCTCACAGGCAGGCGGCGCTGGCGAGCCCCGCGGT
TCCGGAGCCCAGCGCCCGGCCGCGGCCGCAGCCGCTGGATGAACTCAAGCGCTTCTTTGAGGCT
GCGGCAGAGGACGGAGCGAGCTTGCAGCGGCAGCCGGAGGCCGGAGGCCGGTTGCACCCCGCCC
TTCAGGACGGCTGTCCGGTACTGGGGCAGTTGCCGCCGCTCGTTGCTCCGTCACTGCTAGAGCA
GGAGGTGCTCCGGGTGCGTGAGCGCGAGCGGGAGCTGCAGCTGCAGCGGCGCAGCATCTACGGG
GCAGCCGAGGACCGGGAGCCAGCGCCGAGCCTCACCCGATCCCCAGATCTATCCGACCTGTCTT
GGAGTCTTGGCGTCTTGCGTTCTCCGAGAGCAGGGGAGATGGAAAGTTGGCGGTGACCTGGCCC
CCGCGGAGACAGGCCTCAGAGAACGGCCTGGAGAAGGAGCGCAGACCCTGAGGTCTGTGAAGGT
TGGGGCCTGCGGCCAGAAGTAACATGCCCTTTGGAGAACCAGGGTAGGGTTATCCTCCAGATCA
GCAGAAGGCCTAGAGAGGGAAGGCCCAGCTTTCTTTAATGGAAACTTGAAATTCAGCCCATCCC
TGATACTGACTATGGAATTAACCACCTCTCTCCATAAAAGTGTTTAGTCTTCCCTGGAAAATAG
ACCACCGCCCGCAAAACCTGAGTGAAACATACAATAAAGTTCTCCTCCCTTTTCCTGGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100631	(Get FASTA)	NCBI Sequence Viewer
	XP_006255311	(Get FASTA)	NCBI Sequence Viewer
	XP_017456742	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL92245	(Get FASTA)	NCBI Sequence Viewer
	EDL92246	(Get FASTA)	NCBI Sequence Viewer
	EDL92247	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007519
	ENSRNOP00000007519.5
	ENSRNOP00000081833.1
	ENSRNOP00000091192
	ENSRNOP00000091192.1

RefSeq Acc Id:

NP_001100631 ⟸ NM_001107161

- UniProtKB:

D4A1K4 (UniProtKB/TrEMBL), A6IYB7 (UniProtKB/TrEMBL), A0A8I5ZT17 (UniProtKB/TrEMBL)

- Sequence:

show sequence

METPIQREIRRSCEREESLRRSRGLSPGRAGEELIELRVRPVLSRPGSGIPLPRALERARAGAK
MQRDIEREAHRQAALASPAVPEPSARPRPQPLDELKRFFEAAAEDGASLQRQPEAGGRLHPALQ
DGCPVLGQLPPLVAPSLLEQEVLRVRERERELQLQRRSIYGAAEDREPAPSLTQSRGDGKLAVT
WPPRRQASENGLEKERRP

hide sequence

RefSeq Acc Id:	XP_006255311 ⟸ XM_006255249
- Peptide Label:	isoform X1
- UniProtKB:	D4A1K4 (UniProtKB/TrEMBL), A6IYB7 (UniProtKB/TrEMBL), A0A8I5ZT17 (UniProtKB/TrEMBL)
- Sequence:	show sequence METPIQREIRRSCEREESLRRSRGLSPGRAGEELIELRVRPVLSRPGSGIPLPRALERARAGAK MQRDIEREAHRQAALASPAVPEPSARPRPQPLDELKRFFEAAAEDGASLQRQPEAGGRLHPALQ DGCPVLGQLPPLVAPSLLEQEVLRVRERERELQLQRRSIYGAAEDREPAPSLTQSRGDGKLAVT WPPRRQASENGLEKERRP hide sequence

RefSeq Acc Id:	XP_017456742 ⟸ XM_017601253
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AD95 (UniProtKB/TrEMBL), A6IYB8 (UniProtKB/TrEMBL), A0A8I5ZT17 (UniProtKB/TrEMBL)
- Sequence:	show sequence METPIQREIRRSCEREESLRRSRGLSPGRAGEELIELRVRPVLSRPGSGIPLPRALERARAGAK MQRDIEREAHRQAALASPAVPEPSARPRPQPLDELKRFFEAAAEDGASLQRQPEAGGRLHPALQ DGCPVLGQLPPLVAPSLLEQEVLRVRERERELQLQRRSIYGAAEDREPAPSLTRSPDLSDLSWS LGVLRSPRAGEMESWR hide sequence

RefSeq Acc Id:

ENSRNOP00000007519 ⟸ ENSRNOT00000007519

RefSeq Acc Id:

ENSRNOP00000091192 ⟸ ENSRNOT00000112316

RefSeq Acc Id:

ENSRNOP00000081833 ⟸ ENSRNOT00000094433

Protein Domains

A-kinase anchor protein 2 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A1K4-F1-model_v2	AlphaFold	D4A1K4	1-210	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310262	AgrOrtholog
BioCyc Gene	G2FUF-6048	BioCyc
Ensembl Genes	ENSRNOG00000005619	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000007519	ENTREZGENE
	ENSRNOT00000007519.6	UniProtKB/TrEMBL
	ENSRNOT00000094433.1	UniProtKB/TrEMBL
	ENSRNOT00000112316.1	UniProtKB/TrEMBL
InterPro	AKAP2_C	UniProtKB/TrEMBL
	MISP/MISP3	UniProtKB/TrEMBL
KEGG Report	rno:304650	UniProtKB/TrEMBL
NCBI Gene	304650	ENTREZGENE
PANTHER	MISP FAMILY MEMBER 3	UniProtKB/TrEMBL
	PTHR18839	UniProtKB/TrEMBL
Pfam	AKAP2_C	UniProtKB/TrEMBL
PhenoGen	Misp3	PhenoGen
RatGTEx	ENSRNOG00000005619	RatGTEx
UniProt	A0A8I5ZT17	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AD95	ENTREZGENE, UniProtKB/TrEMBL
	A6IYB7	ENTREZGENE, UniProtKB/TrEMBL
	A6IYB8	ENTREZGENE, UniProtKB/TrEMBL
	D4A1K4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-21	Misp3	MISP family member 3	RGD1310262	hypothetical LOC304650	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1310262	hypothetical LOC304650	RGD1310262_predicted	hypothetical LOC304650 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1310262_predicted	hypothetical LOC304650 (predicted)	LOC304650_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC304650_predicted	hypothetical LOC304650 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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