Fktn (fukutin) - Rat Genome Database

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Gene: Fktn (fukutin) Rattus norvegicus
Analyze
Symbol: Fktn
Name: fukutin
RGD ID: 1310087
Description: Predicted to enable phosphotransferase activity, for other substituted phosphate groups. Predicted to be involved in negative regulation of JNK cascade; negative regulation of cell population proliferation; and protein O-linked mannosylation. Predicted to act upstream of or within basement membrane organization; brain development; and skeletal muscle fiber differentiation. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy (multiple) and muscular dystrophy (multiple). Orthologous to human FKTN (fukutin); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fcmd; Fukuyama type congenital muscular dystrophy (fukutin); Fukuyama type congenital muscular dystrophy homolog; Fukuyama type congenital muscular dystrophy homolog (human); LOC362520; ribitol-5-phosphate transferase FKTN
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8573,134,746 - 73,191,772 (+)NCBIGRCr8
mRatBN7.2568,339,803 - 68,396,412 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl568,340,028 - 68,396,409 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx570,227,762 - 70,281,805 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0572,044,733 - 72,098,826 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0572,016,575 - 72,070,620 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0570,522,001 - 70,578,270 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl570,528,688 - 70,578,273 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0574,697,518 - 74,754,106 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4571,155,051 - 71,208,525 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1571,168,040 - 71,211,945 (+)NCBI
Celera567,234,078 - 67,287,987 (+)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Founder Fukutin mutation causes Walker-Warburg syndrome in four Ashkenazi Jewish families. Chang W, etal., Prenat Diagn. 2009 Jun;29(6):560-9. doi: 10.1002/pd.2238.
2. Development of rabbit monoclonal antibodies for detection of alpha-dystroglycan in normal and dystrophic tissue. Fortunato MJ, etal., PLoS One. 2014 May 13;9(5):e97567. doi: 10.1371/journal.pone.0097567. eCollection 2014.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Fukutin gene mutations in steroid-responsive limb girdle muscular dystrophy. Godfrey C, etal., Ann Neurol. 2006 Nov;60(5):603-10.
6. Selective deficiency of alpha-dystroglycan in Fukuyama-type congenital muscular dystrophy. Hayashi YK, etal., Neurology. 2001 Jul 10;57(1):115-21.
7. An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy. Kobayashi K, etal., Nature. 1998 Jul 23;394(6691):388-92.
8. Novel mutations and genotype-phenotype relationships in 107 families with Fukuyama-type congenital muscular dystrophy (FCMD). Kondo-Iida E, etal., Hum Mol Genet. 1999 Nov;8(12):2303-9.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Fukutin gene mutations cause dilated cardiomyopathy with minimal muscle weakness. Murakami T, etal., Ann Neurol. 2006 Nov;60(5):597-602.
11. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
12. Further evidence of Fukutin mutations as a cause of childhood onset limb-girdle muscular dystrophy without mental retardation. Puckett RL, etal., Neuromuscul Disord. 2009 May;19(5):352-6. doi: 10.1016/j.nmd.2009.03.001. Epub 2009 Apr 1.
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Fukutin protein is expressed in neurons of the normal developing human brain but is reduced in Fukuyama-type congenital muscular dystrophy brain. Saito Y, etal., Ann Neurol. 2000 Jun;47(6):756-64.
17. Four Caucasian patients with mutations in the fukutin gene and variable clinical phenotype. Vuillaumier-Barrot S, etal., Neuromuscul Disord. 2009 Mar;19(3):182-8. doi: 10.1016/j.nmd.2008.12.005.
18. Fukutin mutations in non-Japanese patients with congenital muscular dystrophy: less severe mutations predominate in patients with a non-Walker-Warburg phenotype. Yis U, etal., Neuromuscul Disord. 2011 Jan;21(1):20-30. doi: 10.1016/j.nmd.2010.08.007. Epub 2010 Oct 18.
Additional References at PubMed
PMID:12471058   PMID:15213246   PMID:17034757   PMID:18808525   PMID:25279699  


Genomics

Comparative Map Data
Fktn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8573,134,746 - 73,191,772 (+)NCBIGRCr8
mRatBN7.2568,339,803 - 68,396,412 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl568,340,028 - 68,396,409 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx570,227,762 - 70,281,805 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0572,044,733 - 72,098,826 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0572,016,575 - 72,070,620 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0570,522,001 - 70,578,270 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl570,528,688 - 70,578,273 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0574,697,518 - 74,754,106 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4571,155,051 - 71,208,525 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1571,168,040 - 71,211,945 (+)NCBI
Celera567,234,078 - 67,287,987 (+)NCBICelera
Cytogenetic Map5q24NCBI
FKTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389105,558,130 - 105,641,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9105,558,122 - 105,653,820 (+)EnsemblGRCh38hg38GRCh38
GRCh379108,320,411 - 108,403,399 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369107,360,232 - 107,443,220 (+)NCBINCBI36Build 36hg18NCBI36
Build 349105,399,978 - 105,482,953NCBI
Celera978,825,571 - 78,908,566 (+)NCBICelera
Cytogenetic Map9q31.2NCBI
HuRef977,921,830 - 78,004,880 (+)NCBIHuRef
CHM1_19108,467,406 - 108,550,392 (+)NCBICHM1_1
T2T-CHM13v2.09117,732,799 - 117,815,798 (+)NCBIT2T-CHM13v2.0
Fktn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39453,713,745 - 53,765,785 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl453,713,998 - 53,777,890 (+)EnsemblGRCm39 Ensembl
GRCm38453,714,107 - 53,765,785 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl453,713,998 - 53,777,890 (+)EnsemblGRCm38mm10GRCm38
MGSCv37453,727,054 - 53,776,143 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36453,735,282 - 53,784,371 (+)NCBIMGSCv36mm8
Celera453,671,147 - 53,720,238 (+)NCBICelera
Cytogenetic Map4B2NCBI
cM Map428.74NCBI
Fktn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541920,933,662 - 20,994,793 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541920,933,662 - 20,994,793 (-)NCBIChiLan1.0ChiLan1.0
FKTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21133,736,875 - 33,835,805 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1933,739,744 - 33,839,021 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0976,723,071 - 76,821,611 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19104,849,447 - 104,926,414 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9104,849,496 - 104,925,422 (+)Ensemblpanpan1.1panPan2
FKTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11161,394,002 - 61,462,056 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1161,405,034 - 61,461,396 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1159,854,900 - 59,922,736 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01162,541,606 - 62,598,262 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1162,530,493 - 62,597,602 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11161,048,756 - 61,131,662 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01161,079,051 - 61,135,687 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01161,760,632 - 61,835,969 (+)NCBIUU_Cfam_GSD_1.0
Fktn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947176,585,787 - 176,685,702 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365596,581,622 - 6,581,948 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049365596,619,531 - 6,670,727 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365596,612,318 - 6,680,690 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FKTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11246,852,387 - 246,916,650 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21276,542,569 - 276,576,326 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FKTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11233,872,165 - 33,964,105 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1233,900,362 - 33,953,377 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660358,677,300 - 8,770,035 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fktn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247585,792,514 - 5,877,709 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247585,750,804 - 5,877,797 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fktn
215 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:176
Count of miRNA genes:119
Interacting mature miRNAs:152
Transcripts:ENSRNOT00000036799
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1598814Mcs13Mammary carcinoma susceptibility QTL 130.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)56319089069927503Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat

Markers in Region
RH135333  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2568,339,107 - 68,339,304 (+)MAPPERmRatBN7.2
Rnor_6.0570,521,306 - 70,521,502NCBIRnor6.0
Rnor_5.0574,697,162 - 74,697,358UniSTSRnor5.0
RGSC_v3.4571,154,357 - 71,154,553UniSTSRGSC3.4
Celera567,233,384 - 67,233,580UniSTS
RH 3.4 Map5466.8UniSTS
Cytogenetic Map5q24UniSTS
RH140020  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2568,393,312 - 68,393,493 (+)MAPPERmRatBN7.2
Rnor_6.0570,575,169 - 70,575,349NCBIRnor6.0
Rnor_5.0574,751,005 - 74,751,185UniSTSRnor5.0
RGSC_v3.4571,208,015 - 71,208,195UniSTSRGSC3.4
Celera567,287,477 - 67,287,657UniSTS
RH 3.4 Map5467.4UniSTS
Cytogenetic Map5q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 30 26 17 6 17 5 6 74 35 37 11 5
Low 13 31 24 13 24 3 5 4 3
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005504478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC118841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000036799   ⟹   ENSRNOP00000032995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl568,340,028 - 68,396,409 (+)Ensembl
Rnor_6.0 Ensembl570,528,688 - 70,578,273 (+)Ensembl
RefSeq Acc Id: NM_001108667   ⟹   NP_001102137
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,162 - 73,189,181 (+)NCBI
mRatBN7.2568,339,803 - 68,393,823 (+)NCBI
Rnor_6.0570,522,001 - 70,575,679 (+)NCBI
Rnor_5.0574,697,518 - 74,754,106 (+)NCBI
RGSC_v3.4571,155,051 - 71,208,525 (+)RGD
Celera567,234,078 - 67,287,987 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238166   ⟹   XP_006238228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
mRatBN7.2568,339,899 - 68,396,412 (+)NCBI
Rnor_6.0570,522,177 - 70,578,270 (+)NCBI
Rnor_5.0574,697,518 - 74,754,106 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238169   ⟹   XP_006238231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,371 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,396,412 (+)NCBI
Rnor_6.0570,522,239 - 70,578,270 (+)NCBI
Rnor_5.0574,697,518 - 74,754,106 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763712   ⟹   XP_008761934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,366 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,396,412 (+)NCBI
Rnor_6.0570,522,239 - 70,578,270 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039110244   ⟹   XP_038966172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,386 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,396,412 (+)NCBI
RefSeq Acc Id: XM_039110247   ⟹   XP_038966175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,373 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,392,141 (+)NCBI
RefSeq Acc Id: XM_039110248   ⟹   XP_038966176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,365 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,392,110 (+)NCBI
RefSeq Acc Id: XM_039110249   ⟹   XP_038966177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,373 - 73,191,772 (+)NCBI
mRatBN7.2568,340,041 - 68,392,141 (+)NCBI
RefSeq Acc Id: XM_063287921   ⟹   XP_063143991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287923   ⟹   XP_063143993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,400 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287924   ⟹   XP_063143994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,140,508 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287925   ⟹   XP_063143995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287926   ⟹   XP_063143996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287927   ⟹   XP_063143997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287928   ⟹   XP_063143998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,382 - 73,191,772 (+)NCBI
RefSeq Acc Id: XM_063287929   ⟹   XP_063143999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,134,746 - 73,191,772 (+)NCBI
RefSeq Acc Id: XR_005504477
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,400 - 73,169,531 (+)NCBI
mRatBN7.2568,340,041 - 68,374,268 (+)NCBI
RefSeq Acc Id: XR_005504478
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8573,135,400 - 73,187,420 (+)NCBI
mRatBN7.2568,340,041 - 68,392,056 (+)NCBI
RefSeq Acc Id: NP_001102137   ⟸   NM_001108667
- UniProtKB: D3ZI33 (UniProtKB/TrEMBL),   A6KDP7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238228   ⟸   XM_006238166
- Peptide Label: isoform X1
- UniProtKB: D3ZI33 (UniProtKB/TrEMBL),   A6KDP7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238231   ⟸   XM_006238169
- Peptide Label: isoform X1
- UniProtKB: D3ZI33 (UniProtKB/TrEMBL),   A6KDP7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761934   ⟸   XM_008763712
- Peptide Label: isoform X1
- UniProtKB: D3ZI33 (UniProtKB/TrEMBL),   A6KDP7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000032995   ⟸   ENSRNOT00000036799
RefSeq Acc Id: XP_038966172   ⟸   XM_039110244
- Peptide Label: isoform X1
- UniProtKB: D3ZI33 (UniProtKB/TrEMBL),   A6KDP7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966175   ⟸   XM_039110247
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038966177   ⟸   XM_039110249
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038966176   ⟸   XM_039110248
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063143995   ⟸   XM_063287925
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063143991   ⟸   XM_063287921
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063143996   ⟸   XM_063287926
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063143997   ⟸   XM_063287927
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063143999   ⟸   XM_063287929
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063143998   ⟸   XM_063287928
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063143993   ⟸   XM_063287923
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063143994   ⟸   XM_063287924
- Peptide Label: isoform X1
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZI33-F1-model_v2 AlphaFold D3ZI33 1-461 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310087 AgrOrtholog
BioCyc Gene G2FUF-41265 BioCyc
Ensembl Genes ENSRNOG00000028129 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036799.6 UniProtKB/TrEMBL
InterPro FKTN_N UniProtKB/TrEMBL
  Fukutin-related UniProtKB/TrEMBL
  LicD UniProtKB/TrEMBL
KEGG Report rno:362520 UniProtKB/TrEMBL
NCBI Gene 362520 ENTREZGENE
PANTHER FUKUTIN UniProtKB/TrEMBL
  Fukutin-related UniProtKB/TrEMBL
Pfam FKTN_N UniProtKB/TrEMBL
  LicD UniProtKB/TrEMBL
PhenoGen Fktn PhenoGen
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028129 RatGTEx
UniProt A6KDP7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZI33 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-25 Fktn  fukutin  Fcmd_predicted  Fukuyama type congenital muscular dystrophy homolog (human) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Fcmd_predicted  Fukuyama type congenital muscular dystrophy homolog (human) (predicted)    Fukuyama type congenital muscular dystrophy (fukutin) (predicted)  Name updated 1299863 APPROVED
2005-01-12 Fcmd_predicted  Fukuyama type congenital muscular dystrophy (fukutin) (predicted)      Symbol and Name status set to approved 70820 APPROVED