Gene: Crb1 (crumbs 1, cell polarity complex component) Rattus norvegicus
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Symbol: Crb1
Name: crumbs 1, cell polarity complex component
Description: ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN eye photoreceptor cell development (ortholog); membrane organization (ortholog); plasma membrane organization (ortholog); ASSOCIATED WITH abnormal Muller cell morphology; abnormal retinal pigmentation; disorganized retinal outer nuclear layer; ASSOCIATED WITH Idiopathic Juxtafoveal Retinal Telangiectasia; cone-rod dystrophy (ortholog); cone-rod dystrophy (ortholog); FOUND IN microvillus; photoreceptor inner segment; cell-cell adherens junction (ortholog); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); all-trans-retinoic acid (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: crumbs family member 1, photoreceptor morphogenesis associated; crumbs homolog 1; crumbs homolog 1 (Drosophila); LOC304825
Orthologs:
Homo sapiens (human) : CRB1 (crumbs 1, cell polarity complex component)  HGNC  AGR
Mus musculus (house mouse) : Crb1 (crumbs family member 1, photoreceptor morphogenesis associated)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Crb1 (crumbs 1, cell polarity complex component)
Pan paniscus (bonobo/pygmy chimpanzee) : CRB1 (crumbs 1, cell polarity complex component)
Canis lupus familiaris (dog) : CRB1 (crumbs 1, cell polarity complex component)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crb1 (crumbs 1, cell polarity complex component)
more info ...
Allele / Splice: Crb1m1  
Genetic Models: BN-Crb1m1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01356,270,519 - 56,462,893 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01361,292,273 - 61,369,526 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01361,413,282 - 61,480,872 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41352,558,317 - 52,725,099 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11352,572,656 - 52,715,591 (-)NCBI
Celera1351,073,846 - 51,253,703 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Crb1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309947
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-11-28
Status: ACTIVE