Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of ARFGEF3 mRNA | CTD | PMID:24763279 | 1,1-dichloroethene | decreases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of ARFGEF3 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | decreases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ARFGEF3 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of ARFGEF3 mRNA | CTD | PMID:29097150 | 17beta-estradiol | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of ARFGEF3 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARFGEF3 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARFGEF3 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARFGEF3 mRNA | CTD | PMID:19465110 | 2-palmitoylglycerol | increases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of ARFGEF3 mRNA | CTD | PMID:37199045 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | ARFGEF3 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of ARFGEF3 gene | CTD | PMID:31601247 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ARFGEF3 mRNA | CTD | PMID:24780913 | acrylamide | affects expression | EXP | | 6480464 | Acrylamide affects the expression of ARFGEF3 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ARFGEF3 intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ARFGEF3 mRNA | CTD | PMID:21934132 | aristolochic acid A | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ARFGEF3 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ARFGEF3 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ARFGEF3 gene | CTD | PMID:25304211 | benzo[a]pyrene | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ARFGEF3 mRNA | CTD | PMID:21632981 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ARFGEF3 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | increases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of ARFGEF3 mRNA | CTD | PMID:35598803 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ARFGEF3 mRNA | CTD | PMID:29097150 | caffeine | affects phosphorylation | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of ARFGEF3 protein | CTD | PMID:35688186 | calcitriol | increases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of ARFGEF3 mRNA | CTD | PMID:26485663 | carbon nanotube | increases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cefaloridine | decreases expression | EXP | | 6480464 | Cephaloridine results in decreased expression of ARFGEF3 mRNA | CTD | PMID:18500788 | chlorpyrifos | decreases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of ARFGEF3 mRNA | CTD | PMID:37019170 | cisplatin | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ARFGEF3 mRNA | CTD | PMID:27392435 | coumestrol | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | coumestrol | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of ARFGEF3 mRNA | CTD | PMID:19167446 | cyclosporin A | increases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ARFGEF3 mRNA | CTD | PMID:20106945 more ... | dorsomorphin | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of ARFGEF3 mRNA | CTD | PMID:29391264 | Enterolactone | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ARFGEF3 mRNA | CTD | PMID:19167446 | folic acid | decreases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of ARFGEF3 mRNA | CTD | PMID:25629700 | genistein | decreases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | Genistein results in decreased expression of ARFGEF3 mRNA | CTD | PMID:32186404 | mercury dichloride | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of ARFGEF3 mRNA | CTD | PMID:27188386 | nickel atom | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Nickel results in decreased expression of ARFGEF3 mRNA | CTD | PMID:24768652 and PMID:25583101 | panobinostat | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of ARFGEF3 mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARFGEF3 mRNA | CTD | PMID:27188386 | phenylmercury acetate | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of ARFGEF3 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARFGEF3 mRNA | CTD | PMID:27188386 | poly(I:C) | multiple interactions | EXP | | 6480464 | [Poly I-C co-treated with HU 211] results in decreased expression of ARFGEF3 mRNA | CTD | PMID:26923065 | potassium chromate | increases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of ARFGEF3 mRNA | CTD | PMID:22714537 | potassium dichromate | increases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of ARFGEF3 mRNA | CTD | PMID:23608068 | quercetin | increases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Quercetin results in increased expression of ARFGEF3 mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in decreased expression of ARFGEF3 mRNA | CTD | PMID:19167446 | SB 431542 | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of ARFGEF3 mRNA | CTD | PMID:25895662 | sotorasib | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ARFGEF3 mRNA | CTD | PMID:36139627 | succimer | multiple interactions | ISO | Arfgef3 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ARFGEF3 mRNA | CTD | PMID:21641980 | sulforaphane | decreases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | sulforaphane results in decreased expression of ARFGEF3 mRNA | CTD | PMID:30529165 | sunitinib | increases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of ARFGEF3 mRNA | CTD | PMID:31533062 | testosterone | decreases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | Testosterone deficiency results in decreased expression of ARFGEF3 mRNA | CTD | PMID:33848595 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of ARFGEF3 mRNA | CTD | PMID:30723492 and PMID:31150632 | thimerosal | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of ARFGEF3 mRNA | CTD | PMID:27188386 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ARFGEF3 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | Arfgef3 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ARFGEF3 mRNA | CTD | PMID:23557971 | trametinib | multiple interactions | ISO | ARFGEF3 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ARFGEF3 mRNA | CTD | PMID:36139627 | trichostatin A | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ARFGEF3 mRNA | CTD | PMID:24935251 | valproic acid | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ARFGEF3 mRNA | CTD | PMID:24935251 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of ARFGEF3 mRNA | CTD | PMID:29427782 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of ARFGEF3 mRNA | CTD | PMID:29427782 | valproic acid | increases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ARFGEF3 mRNA | CTD | PMID:28001369 | vorinostat | decreases expression | ISO | ARFGEF3 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of ARFGEF3 mRNA | CTD | PMID:27188386 | |