Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of PLAAT1 mRNA | CTD | PMID:26496021 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PLAAT1 mRNA | CTD | PMID:32109520 | 2-hydroxypropanoic acid | decreases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PLAAT1 mRNA | CTD | PMID:30851411 | 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | EXP | | 6480464 | [3 more ... | CTD | PMID:30744511 | 3,4,5,3',4',5'-Hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [3 more ... | CTD | PMID:30744511 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of HRASLS mRNA and Propylthiouracil results in decreased expression of PLAAT1 mRNA | CTD | PMID:24780913 more ... | acetohydrazide | decreases expression | ISO | Plaat1 (Mus musculus) | 6480464 | acetylhydrazine results in decreased expression of PLAAT1 mRNA | CTD | PMID:15282401 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of PLAAT1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of PLAAT1 mRNA | CTD | PMID:25378103 | all-trans-retinoic acid | increases expression | ISO | Plaat1 (Mus musculus) | 6480464 | Tretinoin results in increased expression of HRASLS mRNA | CTD | PMID:36189433 | all-trans-retinoic acid | multiple interactions | ISO | Plaat1 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HRASLS mRNA | CTD | PMID:36189433 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of HRASLS mRNA | CTD | PMID:30047161 | benzo[a]pyrene | decreases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PLAAT1 mRNA | CTD | PMID:20106945 | benzo[a]pyrene | affects methylation | ISO | PLAAT1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of HRASLS 5' UTR and Benzo(a)pyrene affects the methylation of HRASLS promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of PLAAT1 mRNA and [bisphenol A co-treated with Testosterone] results in increased expression of PLAAT1 mRNA | CTD | PMID:26496021 | bisphenol A | increases methylation | ISO | PLAAT1 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of PLAAT1 gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PLAAT1 mRNA | CTD | PMID:25181051 | butanal | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of PLAAT1 mRNA | CTD | PMID:26079696 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of PLAAT1 mRNA | CTD | PMID:26577399 | cyclosporin A | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PLAAT1 mRNA | CTD | PMID:20106945 | decabromodiphenyl ether | affects expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | decabromobiphenyl ether affects the expression of PLAAT1 mRNA | CTD | PMID:24834073 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of PLAAT1 mRNA | CTD | PMID:25152437 | dorsomorphin | multiple interactions | ISO | PLAAT1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of PLAAT1 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PLAAT1 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | entinostat results in increased expression of PLAAT1 mRNA | CTD | PMID:27188386 | ethanol | increases expression | ISO | Plaat1 (Mus musculus) | 6480464 | Ethanol results in increased expression of PLAAT1 mRNA | CTD | PMID:30319688 | ethanol | affects splicing | ISO | Plaat1 (Mus musculus) | 6480464 | Ethanol affects the splicing of PLAAT1 mRNA | CTD | PMID:30319688 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of PLAAT1 mRNA | CTD | PMID:25539665 | genistein | decreases expression | ISO | Plaat1 (Mus musculus) | 6480464 | Genistein results in decreased expression of HRASLS mRNA | CTD | PMID:32186404 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of HRASLS mRNA | CTD | PMID:30047161 | methylmercury chloride | decreases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of PLAAT1 mRNA | CTD | PMID:28001369 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Plaat1 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HRASLS mRNA | CTD | PMID:36189433 | N-methyl-4-phenylpyridinium | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of PLAAT1 mRNA | CTD | PMID:24810058 | paracetamol | affects expression | ISO | Plaat1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PLAAT1 mRNA | CTD | PMID:17562736 | pentanal | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | pentanal results in increased expression of PLAAT1 mRNA | CTD | PMID:26079696 | phenylephrine | increases expression | EXP | | 6480464 | Phenylephrine results in increased expression of PLAAT1 mRNA | CTD | PMID:18158353 | pioglitazone | multiple interactions | ISO | Plaat1 (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PLAAT1 mRNA | CTD | PMID:27935865 | propanal | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of PLAAT1 mRNA | CTD | PMID:26079696 | rac-lactic acid | decreases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of PLAAT1 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | PLAAT1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of PLAAT1 mRNA | CTD | PMID:23806026 | sodium arsenite | decreases expression | ISO | Plaat1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of PLAAT1 mRNA | CTD | PMID:37682722 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of HRASLS mRNA | CTD | PMID:30047161 | temozolomide | decreases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of PLAAT1 mRNA | CTD | PMID:31758290 | testosterone | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of PLAAT1 mRNA | CTD | PMID:26496021 | thimerosal | decreases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of PLAAT1 mRNA | CTD | PMID:27188386 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of PLAAT1 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | Plaat1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PLAAT1 mRNA | CTD | PMID:23557971 | triadimefon | decreases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | triadimefon results in decreased expression of HRASLS mRNA | CTD | PMID:26705709 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of HRASLS mRNA | CTD | PMID:33387578 | trichostatin A | multiple interactions | ISO | PLAAT1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLAAT1 mRNA | CTD | PMID:27188386 | trichostatin A | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PLAAT1 mRNA | CTD | PMID:24935251 more ... | triclosan | decreases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of PLAAT1 mRNA | CTD | PMID:30510588 | valproic acid | affects expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PLAAT1 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | PLAAT1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLAAT1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PLAAT1 mRNA | CTD | PMID:23179753 more ... | vorinostat | increases expression | ISO | PLAAT1 (Homo sapiens) | 6480464 | Vorinostat results in increased expression of PLAAT1 mRNA | CTD | PMID:26272509 and PMID:27188386 | vorinostat | multiple interactions | ISO | PLAAT1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLAAT1 mRNA | CTD | PMID:27188386 | |