Gene: Mmel1 (membrane metallo-endopeptidase-like 1) Rattus norvegicus
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Symbol: Mmel1
Name: membrane metallo-endopeptidase-like 1
Description: ENCODES a protein that exhibits metalloendopeptidase activity; zinc ion binding; INVOLVED IN proteolysis (inferred); ASSOCIATED WITH Arthritis, Rheumatoid (ortholog); Liver Cirrhosis, Biliary (ortholog); primary biliary cirrhosis (ortholog); FOUND IN extracellular space; membrane; endoplasmic reticulum (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; furan
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC313755; mel transforming oncogene-like 1; Mell1; NEP2; NEP2(m); NEPII; neprilysin 2; neprilysin II; neprilysin-2; NL2
Orthologs:
Homo sapiens (human) : MMEL1 (membrane metalloendopeptidase like 1)  HGNC  AGR
Mus musculus (house mouse) : Mmel1 (membrane metallo-endopeptidase-like 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Mmel1 (membrane metalloendopeptidase like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MMEL1 (membrane metalloendopeptidase like 1)
Canis lupus familiaris (dog) : MMEL1 (membrane metalloendopeptidase like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmel1 (membrane metalloendopeptidase like 1)
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Allele / Splice: Mmel1Tn(sb-T2/Bart3)2.255Mcwi  
Genetic Models: F344-Mmel1Tn(sb-T2/Bart3)2.255Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05172,273,450 - 172,303,905 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05175,729,143 - 175,759,868 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45171,675,007 - 171,703,353 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15171,683,479 - 171,713,539 (+)NCBI
Celera5163,639,889 - 163,668,234 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mmel1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309299
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE