Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of UNC5D mRNA] | CTD | PMID:31150632 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of UNC5D mRNA | CTD | PMID:29097150 | 17beta-estradiol | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of UNC5D mRNA | CTD | PMID:30165855 | 4,4'-sulfonyldiphenol | increases methylation | ISO | UNC5D (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of UNC5D gene | CTD | PMID:31601247 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of UNC5D mRNA | CTD | PMID:25825206 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of UNC5D mRNA | CTD | PMID:31881176 | acrolein | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of UNC5D mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of UNC5D mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases methylation | ISO | UNC5D (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of UNC5D gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of UNC5D mRNA | CTD | PMID:23724009 | allethrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of UNC5D protein | CTD | PMID:34896426 | alpha-pinene | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of UNC5D mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of UNC5D mRNA | CTD | PMID:32699268 | arsenite(3-) | increases expression | ISO | Unc5d (Mus musculus) | 6480464 | arsenite results in increased expression of UNC5D mRNA | CTD | PMID:33053406 | arsenous acid | decreases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of UNC5D mRNA | CTD | PMID:26705709 | benzo[a]pyrene | increases methylation | ISO | UNC5D (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of UNC5D 3' UTR and Benzo(a)pyrene results in increased methylation of UNC5D promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of UNC5D mRNA | CTD | PMID:31163220 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with tributyltin] results in decreased expression of UNC5D mRNA | CTD | PMID:31129395 | bisphenol A | increases expression | ISO | Unc5d (Mus musculus) | 6480464 | bisphenol A results in increased expression of UNC5D mRNA | CTD | PMID:35598803 | bisphenol A | decreases expression | ISO | Unc5d (Mus musculus) | 6480464 | bisphenol A results in decreased expression of UNC5D mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of UNC5D mRNA | CTD | PMID:30816183 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of UNC5D mRNA | CTD | PMID:19167457 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of UNC5D promoter | CTD | PMID:22457795 | chlordecone | increases expression | ISO | Unc5d (Mus musculus) | 6480464 | Chlordecone results in increased expression of UNC5D mRNA | CTD | PMID:33711761 | cyhalothrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of UNC5D protein | CTD | PMID:34896426 | cypermethrin | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of UNC5D protein | CTD | PMID:34896426 | diarsenic trioxide | decreases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of UNC5D mRNA | CTD | PMID:26705709 | dorsomorphin | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of UNC5D mRNA | CTD | PMID:29803840 | fenvalerate | multiple interactions | EXP | | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of UNC5D protein | CTD | PMID:34896426 | lipopolysaccharide | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | maneb | multiple interactions | ISO | Unc5d (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in increased expression of UNC5D mRNA | CTD | PMID:36117858 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of UNC5D gene | CTD | PMID:35440735 | methylmercury chloride | decreases expression | ISO | UNC5D (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of UNC5D mRNA | CTD | PMID:28001369 | N-methyl-4-phenylpyridinium | decreases expression | ISO | UNC5D (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of UNC5D mRNA | CTD | PMID:24810058 | ozone | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of UNC5D mRNA more ... | CTD | PMID:32699268 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of UNC5D mRNA | CTD | PMID:35737395 | ozone | multiple interactions | ISO | Unc5d (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of UNC5D mRNA | CTD | PMID:34911549 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of UNC5D mRNA | CTD | PMID:32680482 | paraquat | multiple interactions | ISO | Unc5d (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in increased expression of UNC5D mRNA | CTD | PMID:36117858 | propanal | increases expression | ISO | UNC5D (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of UNC5D mRNA | CTD | PMID:26079696 | pyrethrins | decreases expression | EXP | | 6480464 | Pyrethrins results in decreased expression of UNC5D protein | CTD | PMID:34896426 | resveratrol | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of UNC5D mRNA | CTD | PMID:23557933 | S-(1,2-dichlorovinyl)-L-cysteine | increases expression | ISO | UNC5D (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in increased expression of UNC5D mRNA | CTD | PMID:35811015 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of UNC5D mRNA | CTD | PMID:25895662 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of UNC5D mRNA | CTD | PMID:35314868 | sodium arsenite | decreases expression | ISO | Unc5d (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of UNC5D mRNA | CTD | PMID:36209798 | sunitinib | increases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Sunitinib results in increased expression of UNC5D mRNA | CTD | PMID:31533062 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of UNC5D mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of UNC5D mRNA | CTD | PMID:31150632 | tributylstannane | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with tributyltin] results in decreased expression of UNC5D mRNA | CTD | PMID:31129395 | trichostatin A | decreases expression | ISO | UNC5D (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of UNC5D mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UNC5D mRNA | CTD | PMID:27188386 | triclosan | increases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Triclosan results in increased expression of UNC5D mRNA | CTD | PMID:30510588 | valproic acid | increases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of UNC5D mRNA | CTD | PMID:23179753 and PMID:25192806 | valproic acid | decreases expression | ISO | Unc5d (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of UNC5D mRNA | CTD | PMID:24896083 | valproic acid | decreases expression | ISO | UNC5D (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of UNC5D mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | UNC5D (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of UNC5D mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of UNC5D mRNA | CTD | PMID:29427782 | |