Chial1 (chitinase acidic-like 1) - Rat Genome Database

Name: Chial1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Chial1 (chitinase acidic-like 1) Rattus norvegicus

Analyze

No known orthologs.

Symbol:

Chial1 (Ensembl: RGD1309110)

Name:

chitinase acidic-like 1 (Ensembl:similar to Hypothetical protein MGC58999)

RGD ID:

1309110

Description:

Predicted to enable chitin binding activity and chitinase activity. Predicted to be involved in chitin catabolic process. Predicted to be located in membrane. Predicted to be active in extracellular region. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CHIA (chitinase acidic); INTERACTS WITH titanium dioxide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Acidic mammalian chitinase-like; Chil8; hypothetical protein LOC295352; LOC295352; RGD1309110; similar to Hypothetical protein MGC58999; uncharacterized protein LOC295352

RGD Orthologs

Alliance Genes

More Info

homologs ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Other homologs ²				less info ...
Homo sapiens (human):	CHIA (chitinase acidic)	HGNC	Ensembl, Panther
Homo sapiens (human):	KCNN1 (potassium calcium-activated channel subfamily N member 1)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Chil6 (chitinase-like 6)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CHIA (chitinase acidic)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	CTS2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cht-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	Cht8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Cht11	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Cht12	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Cht5	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	chia	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	196,546,153 - 196,567,652 (-)	NCBI		GRCr8
mRatBN7.2	2	193,858,038 - 193,879,133 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	193,857,344 - 193,879,309 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	201,451,182 - 201,469,489 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	199,357,336 - 199,375,641 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	194,174,299 - 194,192,605 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	208,982,251 - 209,004,270 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	208,983,520 - 209,001,895 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	228,392,388 - 228,413,693 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	201,645,472 - 201,663,684 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	201,607,163 - 201,628,152 (-)	NCBI
Celera	2	186,544,177 - 186,562,482 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

titanium dioxide (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate metabolic process (IEA)

chitin catabolic process (IBA)

Cellular Component

extracellular region (IBA)

membrane (IEA)

Molecular Function

chitin binding (IBA)

chitinase activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:23558346

Genomics

Variants

Variants in Chial1
140 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	67
Count of miRNA genes:	64
Interacting mature miRNAs:	65
Transcripts:	ENSRNOT00000055960
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	168594495	213594495	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
1298083	Bp158	Blood pressure QTL 158	2.62		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189020722	215287351	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	193452645	245889826	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	184114274	202447032	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	184165752	229165752	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	182171407	227171407	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	182171407	227171407	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	182171407	227171407	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150341684	202446871	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	160564068	205564068	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	162765032	207765032	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	182171407	227171407	Rat
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	161699179	222436696	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168358098	223265385	Rat
1331745	Bp203	Blood pressure QTL 203	4.377		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	189599258	218414891	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	157142209	202446871	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	150540301	202447032	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	185876309	219753474	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	185876309	219753474	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	189599258	226936289	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	221167075	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
1598838	Bp290	Blood pressure QTL 290	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166539266	211539266	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189599258	234599258	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	179946951	224946951	Rat
2293084	Iddm26	Insulin dependent diabetes mellitus QTL 26	2.9		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	174930955	213594495	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
61458	Bp10	Blood pressure QTL 10	3.42		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189020722	215287351	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	43154682	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150540301	202447032	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	179335906	224335906	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	157142078	211086598	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	190613715	226808892	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	189599258	234599258	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	endocrine system	hemolymphoid system	integumental system	musculoskeletal system	reproductive system	respiratory system	appendage
High
Medium
Low		2	10
Below cutoff	2	6	9	1	1	1	2	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001134512	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233113	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281655	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000055960 ⟹ ENSRNOP00000052813

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	193,858,441 - 193,879,309 (-)	Ensembl
Rnor_6.0 Ensembl	2	208,983,520 - 209,001,895 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104578 ⟹ ENSRNOP00000081885

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	193,857,831 - 193,879,296 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000108135 ⟹ ENSRNOP00000092706

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	193,857,344 - 193,879,309 (-)	Ensembl

RefSeq Acc Id:

NM_001134512 ⟹ NP_001127984

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,547,422 - 196,565,738 (-)	NCBI
mRatBN7.2	2	193,859,100 - 193,877,419 (-)	NCBI
Rnor_6.0	2	208,983,520 - 209,001,895 (-)	NCBI
Rnor_5.0	2	228,392,388 - 228,413,693 (-)	NCBI
RGSC_v3.4	2	201,645,472 - 201,663,684 (-)	RGD
Celera	2	186,544,177 - 186,562,482 (-)	RGD

Sequence:

show sequence

ATGTATGTTCTGTTTCCAGGACTCAACCTCCTACTGAATGTTCAACTTGACTCTGCCTACCAGC
TGATGTGTTACTTCAACAACTGGCCTCAGTATCAGCCAGATGTGAGAGGTATGAAGCTTGATGA
CATTGACCCTTGCCTCTGTACTCACCTAATCTATTCTTTTGCTGGGATTTGGGAAAACAACAAC
ACCATGACCAAAAGGAAAGATTTGGATGACTACAAAGAATTTAATGATTTAAAAAAGAGAAACA
ACAAGCTGAAAACACTCCTGTCTATTGGTTGCTGGAACTTTGAAGCTGGTCTTTTTATCACCAT
GGTGTCAACTCCTGAGAGCCGCCACACTTTCATTACTTCAGTTAGAAAATTCCTGCGAAAGTAT
GGATTTGATGGACTTAACTTAGCTTGGCAGTACCCTGGCTGTTATGGAAGCCCTCCTAAGGACA
AACATCTCTTTACTATCCTAACACAGGAAATACGTAAAGCTTTTGAAAAGGAGGTGAGCAAGAA
CAAAAAGTCCAGGCTGATAATCACTGCTGCACTTGCCGGTGTCATCTCCCCAATCCAATTTGGC
TATCATGTTCCCCAACTGTCACAGTCTTTGGATTACATTCAAGTCATGACCTATGACCTCCATG
GATCTTGGGATGGTTACACTGGAGAAAACAGTCCTCTCTATAAATCTCCAGCTGAAACTGGAGT
CAAGGCCTTTTACAACATAAAATATACAATGCACAACTGGAAGAACAAAGGGGTATCACCTGAG
AAGCTCATTGTTGGCTTTCCAGCATATGGACACACTTTCATTCTGAGTGACTCCACTAAAACAG
AAATTGGTGCCCCTAGCAATCGTGGTGGCCATCCAGGACCCTACACAAAGAAAACTGGATTCTG
GGCCTATTATGAGATTTGTGCATTCCTGAAAAATGGAGCCATTCAGGTCTGGAATGCTGCTCAG
CAGGTGCCCTATGCCTTCCATGGCAATGAGTGGGTTGGCTATGACAATGTCAAGAGCTTTCACA
TCAAGGCTCAGTGGCTTAAGAACAACAACTTTGGAGGTGCCATGATTTGGGCCATTGGTATGGA
TGACTATACTGGTTCTTTCTGTGATCAGGGCCCATTTCCCCTGACCTCCACCTTGAAGAACGCC
CTCAAAGTGCACAGTGCAAGTAAGTGACAGGAA

hide sequence

RefSeq Acc Id:

XM_006233113 ⟹ XP_006233175

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,546,153 - 196,567,652 (-)	NCBI
mRatBN7.2	2	193,858,038 - 193,879,133 (-)	NCBI
Rnor_6.0	2	208,982,251 - 209,004,270 (-)	NCBI
Rnor_5.0	2	228,392,388 - 228,413,693 (-)	NCBI

Sequence:

show sequence

CTTGGTTTATTCACAAACTTATCCCTATATAGGCTTAAGCACACTCATTATTCTAAGGACTCCT
TAGTGTGGTGAACTTCTCTCATCGTCAAATTTATATATCAAAGTGCCAGTAAGTATCTCAATTT
GACATAACACATCACAGTGTGAATTCATCTCTGCAACCCTTGGCCCTCTGTAACTAACATTCTT
TGAAACCCTAAATACCCCATACCCCACATCTTGGCCATTTCATATAACAAATGTGAATAGAATG
TTAAGGAAGTAGTCCATGAGTAGATAGAAGGAATGATTTAGGCATTGACCATATAAATAGCATG
TGAATAATTCCAAGAACAAACAAGATTCAAACAGAGCTAATAATTTTCAAAGGCTTTTGTTGTT
TACTTGCCAATAGAAACTTGCTTTGATGCCAGGTATGGAAATTCTGTGAAATAAAAACCTGATT
GCCTTATCTCAACAGATTTTTCAGCCTCAACATGTAGGGAAAGGGGTATTAAGGAAGTGAGTAC
TTTGTGTAACTGTGGACTTCACCTCCTGCTAGGATGGATAGCATTAAAAGCAGAGTCTGTAATA
GAGAGATGCTGATTTACAAATCAACCATACATACATTGTAGTAAGCAATTCTTTTTGAAAACTC
TTGTGATTATTAGGGACAGAAATGTTATATAAAACCAGTGAAGACCCTGCTGGATCAGTACTGA
GGGCATTCATATCCAAGCTTGTTTTCATCATGGGACTCAACCTCCTACTGAATGTTCAACTTGA
CTCTGCCTACCAGCTGATGTGTTACTTCAACAACTGGCCTCAGTATCAGCCAGATGTGAGAGGT
ATGAAGCTTGATGACATTGACCCTTGCCTCTGTACTCACCTAATCTATTCTTTTGCTGGGATTT
GGGAAAACAACAACACCATGACCAAAAGGAAAGATTTGGATGACTACAAAGAATTTAATGATTT
AAAAAAGAGAAACAACAAGCTGAAAACACTCCTGTCTATTGGTTGCTGGAACTTTGAAGCTGGT
CTTTTTATCACCATGGTGTCAACTCCTGAGAGCCGCCACACTTTCATTACTTCAGTTAGAAAAT
TCCTGCGAAAGTATGGATTTGATGGACTTAACTTAGCTTGGCAGTACCCTGGCTGTTATGGAAG
CCCTCCTAAGGACAAACATCTCTTTACTATCCTAACACAGGAAATACGTAAAGCTTTTGAAAAG
GAGGTGAGCAAGAACAAAAAGTCCAGGCTGATAATCACTGCTGCACTTGCCGGTGTCATCTCCC
CAATCCAATTTGGCTATCATGTTCCCCAACTGTCACAGTCTTTGGATTACATTCAAGTCATGAC
CTATGACCTCCATGGATCTTGGGATGGTTACACTGGAGAAAACAGTCCTCTCTATAAATCTCCA
GCTGAAACTGGAGTCAAGGCCTTTTACAACATAAAATATACAATGCACAACTGGAAGAACAAAG
GGGTATCACCTGAGAAGCTCATTGTTGGCTTTCCAGCATATGGACACACTTTCATTCTGAGTGA
CTCCACTAAAACAGAAATTGGTGCCCCTAGCAATCGTGGTGGCCATCCAGGACCCTACACAAAG
AAAACTGGATTCTGGGCCTATTATGAGATTTGTGCATTCCTGAAAAATGGAGCCATTCAGGTCT
GGAATGCTGCTCAGCAGGTGCCCTATGCCTTCCATGGCAATGAGTGGGTTGGCTATGACAATGT
CAAGAGCTTTCACATCAAGGCTCAGTGGCTTAAGAACAACAACTTTGGAGGTGCCATGATTTGG
GCCATTGGTATGGATGACTATACTGGTTCTTTCTGTGATCAGGGCCCATTTCCCCTGACCTCCA
CCTTGAAGAACGCCCTCAAAGTGCACAGTGCAAGTTGCAAAGTAACTGCTCTTTCAGCCAATGT
GACTGGTAGCAGGGACAGTAACTTTGGAGCATTGGAGCCTCTATTTCAACTCAGTAGCAAATAA
CACAAGCAGCATCTGGCACCGCCTGAATGGAATCACATTCTAGAACTTCCAGGCAGAATCTGCC
TTCAAGAGCAGCAAACATTGTTGGGCTAGACATAGACACTATCTGATACCTTTCTCCAGGAACT
CTGCATACTGTCTCTTGCCTCTTTCTAGGACCATATCACTTCTACCTAGTACACTAAATTAAAA
TAAGCAGTTAGTTCA

hide sequence

RefSeq Acc Id:

XM_063281655 ⟹ XP_063137725

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,546,153 - 196,567,590 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001127984	(Get FASTA)	NCBI Sequence Viewer
	XP_006233175	(Get FASTA)	NCBI Sequence Viewer
	XP_063137725	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL81837	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000052813.4
	ENSRNOP00000081885.1
	ENSRNOP00000092706
	ENSRNOP00000092706.1

RefSeq Acc Id:	NP_001127984 ⟸ NM_001134512
- Peptide Label:	precursor
- UniProtKB:	D4A2D4 (UniProtKB/TrEMBL), A6HUQ1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYVLFPGLNLLLNVQLDSAYQLMCYFNNWPQYQPDVRGMKLDDIDPCLCTHLIYSFAGIWENNN TMTKRKDLDDYKEFNDLKKRNNKLKTLLSIGCWNFEAGLFITMVSTPESRHTFITSVRKFLRKY GFDGLNLAWQYPGCYGSPPKDKHLFTILTQEIRKAFEKEVSKNKKSRLIITAALAGVISPIQFG YHVPQLSQSLDYIQVMTYDLHGSWDGYTGENSPLYKSPAETGVKAFYNIKYTMHNWKNKGVSPE KLIVGFPAYGHTFILSDSTKTEIGAPSNRGGHPGPYTKKTGFWAYYEICAFLKNGAIQVWNAAQ QVPYAFHGNEWVGYDNVKSFHIKAQWLKNNNFGGAMIWAIGMDDYTGSFCDQGPFPLTSTLKNA LKVHSASK hide sequence

RefSeq Acc Id:	XP_006233175 ⟸ XM_006233113
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GKA9 (UniProtKB/TrEMBL), A0A8I5ZT06 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLYKTSEDPAGSVLRAFISKLVFIMGLNLLLNVQLDSAYQLMCYFNNWPQYQPDVRGMKLDDID PCLCTHLIYSFAGIWENNNTMTKRKDLDDYKEFNDLKKRNNKLKTLLSIGCWNFEAGLFITMVS TPESRHTFITSVRKFLRKYGFDGLNLAWQYPGCYGSPPKDKHLFTILTQEIRKAFEKEVSKNKK SRLIITAALAGVISPIQFGYHVPQLSQSLDYIQVMTYDLHGSWDGYTGENSPLYKSPAETGVKA FYNIKYTMHNWKNKGVSPEKLIVGFPAYGHTFILSDSTKTEIGAPSNRGGHPGPYTKKTGFWAY YEICAFLKNGAIQVWNAAQQVPYAFHGNEWVGYDNVKSFHIKAQWLKNNNFGGAMIWAIGMDDY TGSFCDQGPFPLTSTLKNALKVHSASCKVTALSANVTGSRDSNFGALEPLFQLSSK hide sequence

RefSeq Acc Id:

ENSRNOP00000052813 ⟸ ENSRNOT00000055960

RefSeq Acc Id:

ENSRNOP00000092706 ⟸ ENSRNOT00000108135

RefSeq Acc Id:

ENSRNOP00000081885 ⟸ ENSRNOT00000104578

RefSeq Acc Id:	XP_063137725 ⟸ XM_063281655
- Peptide Label:	isoform X2

Protein Domains

GH18

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A2D4-F1-model_v2	AlphaFold	D4A2D4	1-392	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309110	AgrOrtholog
BioCyc Gene	G2FUF-51709	BioCyc
Ensembl Genes	ENSRNOG00000017574	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000055960.4	UniProtKB/TrEMBL
	ENSRNOT00000104578.1	UniProtKB/TrEMBL
	ENSRNOT00000108135.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.50.10	UniProtKB/TrEMBL
	Glycosidases	UniProtKB/TrEMBL
InterPro	Chitinase_II	UniProtKB/TrEMBL
	Chitinase_insertion	UniProtKB/TrEMBL
	Glyco_hydro18cat	UniProtKB/TrEMBL
	Glyco_hydro_catalytic_core	UniProtKB/TrEMBL
KEGG Report	rno:295352	UniProtKB/TrEMBL
NCBI Gene	295352	ENTREZGENE
PANTHER	CHITINASE	UniProtKB/TrEMBL
	CHITINASE-LIKE 6	UniProtKB/TrEMBL
Pfam	Glyco_hydro_18	UniProtKB/TrEMBL
PhenoGen	Chial1	PhenoGen
PROSITE	GH18_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017574	RatGTEx
SMART	Glyco_18	UniProtKB/TrEMBL
Superfamily-SCOP	Glyco_hydro_cat	UniProtKB/TrEMBL
	SSF54556	UniProtKB/TrEMBL
UniProt	A0A8I5ZT06	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GKA9	ENTREZGENE, UniProtKB/TrEMBL
	A6HUQ1	ENTREZGENE, UniProtKB/TrEMBL
	D4A2D4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-09-19	Chial1	chitinase acidic-like 1	RGD1309110	similar to Hypothetical protein MGC58999	Symbol and Name Changed	1299863	APPROVED
2008-04-30	RGD1309110	similar to Hypothetical protein MGC58999	RGD1309110_predicted	similar to Hypothetical protein MGC58999 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1309110_predicted	similar to Hypothetical protein MGC58999 (predicted)	LOC295352_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC295352_predicted	similar to Hypothetical protein MGC58999 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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