Enpp4 (ectonucleotide pyrophosphatase/phosphodiesterase 4) - Rat Genome Database

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Gene: Enpp4 (ectonucleotide pyrophosphatase/phosphodiesterase 4) Rattus norvegicus
Analyze
Symbol: Enpp4
Name: ectonucleotide pyrophosphatase/phosphodiesterase 4
RGD ID: 1308689
Description: Predicted to enable bis(5'-adenosyl)-triphosphatase activity. Predicted to be involved in positive regulation of blood coagulation and purine ribonucleoside catabolic process. Predicted to be located in plasma membrane. Orthologous to human ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase 4); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: bis(5'-adenosyl)-triphosphatase ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase family member 4; LOC301261
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,386,351 - 24,396,248 (+)NCBIGRCr8
mRatBN7.2916,888,923 - 16,898,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl916,887,739 - 16,898,860 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,473,036 - 25,482,764 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,547,557 - 30,557,287 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0928,836,767 - 28,846,497 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,446,807 - 19,457,946 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,448,269 - 19,457,946 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,325,162 - 18,336,443 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4912,552,834 - 12,562,511 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1912,549,935 - 12,556,776 (+)NCBI
Celera914,615,372 - 14,625,059 (+)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19056867   PMID:19946888   PMID:22995898  


Genomics

Comparative Map Data
Enpp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,386,351 - 24,396,248 (+)NCBIGRCr8
mRatBN7.2916,888,923 - 16,898,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl916,887,739 - 16,898,860 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx925,473,036 - 25,482,764 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,547,557 - 30,557,287 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0928,836,767 - 28,846,497 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,446,807 - 19,457,946 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,448,269 - 19,457,946 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,325,162 - 18,336,443 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4912,552,834 - 12,562,511 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1912,549,935 - 12,556,776 (+)NCBI
Celera914,615,372 - 14,625,059 (+)NCBICelera
Cytogenetic Map9q13NCBI
ENPP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38646,129,989 - 46,146,688 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl646,129,989 - 46,146,688 (+)EnsemblGRCh38hg38GRCh38
GRCh37646,097,726 - 46,114,425 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,205,871 - 46,222,237 (+)NCBINCBI36Build 36hg18NCBI36
Build 34646,205,870 - 46,222,237NCBI
Celera647,650,241 - 47,666,973 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef645,820,747 - 45,837,481 (+)NCBIHuRef
CHM1_1646,100,957 - 46,117,681 (+)NCBICHM1_1
T2T-CHM13v2.0645,965,077 - 45,981,776 (+)NCBIT2T-CHM13v2.0
Enpp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391744,407,198 - 44,416,725 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1744,407,199 - 44,416,700 (-)EnsemblGRCm39 Ensembl
GRCm381744,096,307 - 44,105,809 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1744,096,308 - 44,105,809 (-)EnsemblGRCm38mm10GRCm38
MGSCv371744,233,258 - 44,242,757 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361743,559,364 - 43,568,863 (-)NCBIMGSCv36mm8
Celera1747,517,799 - 47,527,273 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1720.34NCBI
Enpp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,169,778 - 11,188,156 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543711,169,778 - 11,187,544 (+)NCBIChiLan1.0ChiLan1.0
ENPP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2560,622,918 - 60,639,785 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1656,488,983 - 56,505,599 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0645,710,507 - 45,727,215 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1646,984,395 - 47,001,251 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl646,984,395 - 47,001,251 (+)Ensemblpanpan1.1panPan2
ENPP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,353,355 - 14,366,506 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,353,282 - 14,365,952 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1214,385,537 - 14,400,943 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01214,853,731 - 14,869,158 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1214,853,677 - 14,869,136 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,369,849 - 14,385,351 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01214,458,027 - 14,471,937 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01214,554,506 - 14,568,452 (+)NCBIUU_Cfam_GSD_1.0
Enpp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494649,756,158 - 49,771,879 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647614,191,479 - 14,195,618 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647614,188,328 - 14,204,063 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENPP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl740,896,470 - 40,912,426 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1740,896,392 - 40,913,609 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2747,160,730 - 47,171,612 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ENPP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11726,102,687 - 26,117,142 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1726,102,510 - 26,117,080 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604446,140,497 - 46,154,975 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Enpp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475414,305,062 - 14,312,018 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475414,302,709 - 14,316,914 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Enpp4
110 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:793
Count of miRNA genes:218
Interacting mature miRNAs:296
Transcripts:ENSRNOT00000045937, ENSRNOT00000065048
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 10 10 8 10 21 13 13 11
Low 1 43 47 31 11 31 8 11 53 22 28 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000045937   ⟹   ENSRNOP00000050116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl916,887,739 - 16,898,860 (+)Ensembl
Rnor_6.0 Ensembl919,448,269 - 19,457,946 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000065048   ⟹   ENSRNOP00000059215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl916,887,739 - 16,898,860 (+)Ensembl
Rnor_6.0 Ensembl919,451,630 - 19,454,691 (+)Ensembl
RefSeq Acc Id: NM_001106892   ⟹   NP_001100362
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,386,571 - 24,396,248 (+)NCBI
mRatBN7.2916,889,179 - 16,898,860 (+)NCBI
Rnor_6.0919,448,269 - 19,457,946 (+)NCBI
Rnor_5.0918,325,162 - 18,336,443 (+)NCBI
RGSC_v3.4912,552,834 - 12,562,511 (+)RGD
Celera914,615,372 - 14,625,059 (+)RGD
Sequence:
RefSeq Acc Id: XM_006244598   ⟹   XP_006244660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,386,364 - 24,396,162 (+)NCBI
mRatBN7.2916,888,944 - 16,898,776 (+)NCBI
Rnor_6.0919,447,972 - 19,457,862 (+)NCBI
Rnor_5.0918,325,162 - 18,336,443 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244600   ⟹   XP_006244662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,386,351 - 24,396,162 (+)NCBI
mRatBN7.2916,888,923 - 16,898,776 (+)NCBI
Rnor_6.0919,447,952 - 19,457,862 (+)NCBI
Rnor_5.0918,325,162 - 18,336,443 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244601   ⟹   XP_006244663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,386,364 - 24,396,162 (+)NCBI
mRatBN7.2916,888,944 - 16,898,776 (+)NCBI
Rnor_6.0919,446,807 - 19,457,862 (+)NCBI
Rnor_5.0918,325,162 - 18,336,443 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244602   ⟹   XP_006244664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,386,717 - 24,396,162 (+)NCBI
mRatBN7.2916,889,325 - 16,898,776 (+)NCBI
Rnor_6.0919,448,438 - 19,457,862 (+)NCBI
Rnor_5.0918,325,162 - 18,336,443 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008766852   ⟹   XP_008765074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,386,838 - 24,396,162 (+)NCBI
mRatBN7.2916,889,325 - 16,898,776 (+)NCBI
Rnor_6.0919,448,467 - 19,457,862 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017596330   ⟹   XP_017451819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,386,710 - 24,396,162 (+)NCBI
mRatBN7.2916,889,316 - 16,898,776 (+)NCBI
Rnor_6.0919,448,376 - 19,457,862 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063266861   ⟹   XP_063122931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,388,794 - 24,396,162 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001100362   ⟸   NM_001106892
- Peptide Label: precursor
- UniProtKB: A6JJ18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244663   ⟸   XM_006244601
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006244660   ⟸   XM_006244598
- Peptide Label: isoform X1
- UniProtKB: D4A2W1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244662   ⟸   XM_006244600
- Peptide Label: isoform X2
- UniProtKB: F1LTZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244664   ⟸   XM_006244602
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008765074   ⟸   XM_008766852
- Peptide Label: isoform X5
- UniProtKB: A6JJ18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451819   ⟸   XM_017596330
- Peptide Label: isoform X5
- UniProtKB: A6JJ18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000050116   ⟸   ENSRNOT00000045937
RefSeq Acc Id: ENSRNOP00000059215   ⟸   ENSRNOT00000065048
RefSeq Acc Id: XP_063122931   ⟸   XM_063266861
- Peptide Label: isoform X5
- UniProtKB: A6JJ18 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LTZ5-F1-model_v2 AlphaFold F1LTZ5 1-454 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696549
Promoter ID:EPDNEW_R7074
Type:single initiation site
Name:Enpp4_1
Description:ectonucleotide pyrophosphatase/phosphodiesterase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0919,451,608 - 19,451,668EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308689 AgrOrtholog
BioCyc Gene G2FUF-28124 BioCyc
Ensembl Genes ENSRNOG00000010174 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045937.5 UniProtKB/TrEMBL
  ENSRNOT00000065048.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1360.180 UniProtKB/TrEMBL
  3.40.720.10 UniProtKB/TrEMBL
InterPro Alkaline_phosphatase_core UniProtKB/TrEMBL
  Phosphodiest/P_Trfase UniProtKB/TrEMBL
KEGG Report rno:301261 UniProtKB/TrEMBL
NCBI Gene 301261 ENTREZGENE
PANTHER ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE UniProtKB/TrEMBL
  PTHR10151:SF79 UniProtKB/TrEMBL
Pfam Phosphodiest UniProtKB/TrEMBL
PhenoGen Enpp4 PhenoGen
RatGTEx ENSRNOG00000010174 RatGTEx
Superfamily-SCOP Alkaline_phosphatase_core UniProtKB/TrEMBL
UniProt A6JJ18 ENTREZGENE, UniProtKB/TrEMBL
  D4A2W1 ENTREZGENE, UniProtKB/TrEMBL
  F1LTZ5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Enpp4  ectonucleotide pyrophosphatase/phosphodiesterase 4   Enpp4_predicted  ectonucleotide pyrophosphatase/phosphodiesterase 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Enpp4_predicted  ectonucleotide pyrophosphatase/phosphodiesterase 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED