Dipk1a (divergent protein kinase domain 1A)

Gene: Dipk1a (divergent protein kinase domain 1A) Rattus norvegicus

Analyze

Symbol:

Dipk1a

Name:

divergent protein kinase domain 1A

RGD ID:

1308581

Description:

Predicted to be located in endoplasmic reticulum membrane. Orthologous to human DIPK1A (divergent protein kinase domain 1A); INTERACTS WITH 17beta-estradiol; 3-chloropropane-1,2-diol; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Fam69a; family with sequence similarity 69, member A; LOC360906; RGD1308581; similar to RIKEN cDNA 2900024C23

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DIPK1A (divergent protein kinase domain 1A)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Dipk1a (divergent protein kinase domain 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dipk1a (divergent protein kinase domain 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DIPK1A (divergent protein kinase domain 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DIPK1A (divergent protein kinase domain 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dipk1a (divergent protein kinase domain 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DIPK1A (divergent protein kinase domain 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DIPK1A (divergent protein kinase domain 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dipk1a (divergent protein kinase domain 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Dipk1a (divergent protein kinase domain 1A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	DIPK1A (divergent protein kinase domain 1A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C53D5.1	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	dipk1aa	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dipk1ab	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dipk1a	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	1,917,353 - 1,988,188 (+)	NCBI		GRCr8
mRatBN7.2	14	1,772,412 - 1,843,508 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	1,772,422 - 1,843,743 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	1,651,319 - 1,722,153 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	2,953,097 - 3,023,933 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	1,649,782 - 1,720,622 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	2,789,699 - 2,860,354 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	2,789,650 - 2,860,333 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	2,789,914 - 2,860,569 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	2,326,255 - 2,397,029 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	2,360,262 - 2,397,579 (+)	NCBI
Celera	14	1,847,445 - 1,863,186 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aplastic anemia (ISO)

congenital hypoplastic anemia (ISO)

Diamond-Blackfan anemia (ISO)

Diamond-Blackfan anemia 1 (ISO)

Diamond-Blackfan anemia 6 (ISO)

genetic disease (ISO)

severe congenital neutropenia 2 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3-chloropropane-1,2-diol (EXP)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

chlorpyrifos (ISO)

diuron (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

ethyl methanesulfonate (ISO)

fluoranthene (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

furan (ISO)

ketamine (EXP)

lead(0) (ISO)

methamphetamine (EXP)

methyl methanesulfonate (ISO)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

N-nitrosodiethylamine (ISO)

ochratoxin A (ISO)

paracetamol (EXP)

pentachlorophenol (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

rotenone (EXP)

SB 431542 (ISO)

sodium arsenate (ISO)

sunitinib (ISO)

tebufenpyrad (ISO)

tetrachloroethene (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (EXP)

tungsten (ISO)

valproic acid (ISO)

vincaleukoblastine (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

endoplasmic reticulum membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:12477932

Genomics

Comparative Map Data

Dipk1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	1,917,353 - 1,988,188 (+)	NCBI		GRCr8
mRatBN7.2	14	1,772,412 - 1,843,508 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	1,772,422 - 1,843,743 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	1,651,319 - 1,722,153 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	2,953,097 - 3,023,933 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	1,649,782 - 1,720,622 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	2,789,699 - 2,860,354 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	2,789,650 - 2,860,333 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	2,789,914 - 2,860,569 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	2,326,255 - 2,397,029 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	2,360,262 - 2,397,579 (+)	NCBI
Celera	14	1,847,445 - 1,863,186 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

DIPK1A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	92,832,729 - 92,961,462 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	92,832,737 - 92,961,522 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	93,298,286 - 93,427,019 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	93,071,041 - 93,199,601 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	91,561,313 - 91,696,457 (-)	NCBI		Celera
Cytogenetic Map	1	p22.1	NCBI
HuRef	1	91,419,451 - 91,464,002 (-)	NCBI		HuRef
CHM1_1	1	93,413,084 - 93,541,861 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	92,677,871 - 92,806,635 (-)	NCBI		T2T-CHM13v2.0

Dipk1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	108,055,908 - 108,134,943 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	108,055,919 - 108,134,951 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	107,908,042 - 107,987,077 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	107,908,053 - 107,987,085 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	108,337,061 - 108,416,096 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	108,148,640 - 108,227,335 (-)	NCBI		MGSCv36	mm8
Celera	5	105,020,900 - 105,105,133 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	52.23	NCBI

Dipk1a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	1,710,257 - 1,748,651 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955423	1,651,562 - 1,748,651 (+)	NCBI	ChiLan1.0	ChiLan1.0

DIPK1A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	134,054,716 - 134,178,770 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	133,209,618 - 133,334,845 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	95,507,241 - 95,631,286 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	94,241,754 - 94,275,864 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	94,232,632 - 94,275,864 (-)	Ensembl	panpan1.1		panPan2

DIPK1A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	56,134,770 - 56,206,943 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	56,174,719 - 56,205,741 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	58,791,822 - 58,904,822 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	56,466,920 - 56,582,920 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	56,466,920 - 56,585,480 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	56,146,580 - 56,262,555 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	56,124,677 - 56,240,613 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	56,584,362 - 56,700,598 (+)	NCBI		UU_Cfam_GSD_1.0

Dipk1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	102,606,191 - 102,713,196 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936537	6,234,814 - 6,341,777 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936537	6,234,773 - 6,341,782 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DIPK1A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	124,229,560 - 124,359,195 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	124,229,414 - 124,359,339 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	135,970,865 - 135,982,289 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DIPK1A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	40,298,048 - 40,416,324 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	40,298,090 - 40,415,123 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	77,600,048 - 77,723,124 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dipk1a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624742	4,863,045 - 4,972,977 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Dipk1a
239 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	91
Count of miRNA genes:	82
Interacting mature miRNAs:	87
Transcripts:	ENSRNOT00000030479
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300159	Bmd61	Bone mineral density QTL 61	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
2300183	Bmd60	Bone mineral density QTL 60	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
619619	Rf4	Renal disease susceptibility QTL 4	4.1	0.002	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	14	1	32754612	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41131407	Rat
71115	Niddm15	Non-insulin dependent diabetes mellitus QTL 15	4.8		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1217606	11030812	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1217606	16960180	Rat

Markers in Region

D14Rat2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	1,796,308 - 1,796,464 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	2,813,534 - 2,813,689	NCBI	Rnor6.0
Rnor_5.0	14	2,813,749 - 2,813,904	UniSTS	Rnor5.0
RGSC_v3.4	14	2,350,092 - 2,350,247	UniSTS	RGSC3.4
RGSC_v3.4	14	2,350,091 - 2,350,247	RGD	RGSC3.4
RGSC_v3.1	14	2,350,092 - 2,350,247	RGD
Celera	14	1,817,169 - 1,817,324	UniSTS
RH 3.4 Map	14	33.9	RGD
RH 3.4 Map	14	33.9	UniSTS
RH 2.0 Map	14	42.5	RGD
SHRSP x BN Map	14	0.0	RGD
FHH x ACI Map	14	0.0	RGD
Cytogenetic Map	14	p22	UniSTS

D14Uwm16

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	1,837,103 - 1,837,330 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	2,854,211 - 2,854,437	NCBI	Rnor6.0
Rnor_5.0	14	2,854,426 - 2,854,652	UniSTS	Rnor5.0
RGSC_v3.4	14	2,390,886 - 2,391,112	UniSTS	RGSC3.4
Cytogenetic Map	14	p22	UniSTS

BE120083

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	1,842,584 - 1,842,772 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	2,859,692 - 2,859,879	NCBI	Rnor6.0
Rnor_5.0	14	2,859,907 - 2,860,094	UniSTS	Rnor5.0
RGSC_v3.4	14	2,396,367 - 2,396,554	UniSTS	RGSC3.4
Celera	14	1,862,524 - 1,862,711	UniSTS
RH 3.4 Map	14	33.9	UniSTS
Cytogenetic Map	14	p22	UniSTS

RH139679

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	1,842,822 - 1,843,019 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	2,859,930 - 2,860,126	NCBI	Rnor6.0
Rnor_5.0	14	2,860,145 - 2,860,341	UniSTS	Rnor5.0
RGSC_v3.4	14	2,396,605 - 2,396,801	UniSTS	RGSC3.4
Celera	14	1,862,762 - 1,862,958	UniSTS
RH 3.4 Map	14	33.8	UniSTS
Cytogenetic Map	14	p22	UniSTS

AI235218

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	1,843,499 - 1,843,726 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	2,860,607 - 2,860,833	NCBI	Rnor6.0
Rnor_5.0	14	2,860,822 - 2,861,048	UniSTS	Rnor5.0
RGSC_v3.4	14	2,397,282 - 2,397,508	UniSTS	RGSC3.4
Celera	14	1,863,439 - 1,863,665	UniSTS
Cytogenetic Map	14	p22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2		35	27	19	27	8	11	72	21	29	11	8
Low	1	43	22	14		14			2	14	11
Below cutoff											1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001170456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AI706300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211286	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000030479 ⟹ ENSRNOP00000031951

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	1,772,422 - 1,843,660 (+)	Ensembl
Rnor_6.0 Ensembl	14	2,789,650 - 2,860,333 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000112934 ⟹ ENSRNOP00000083362

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	1,826,233 - 1,843,743 (+)	Ensembl

RefSeq Acc Id:

NM_001170456 ⟹ NP_001163927

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,917,353 - 1,988,182 (+)	NCBI
mRatBN7.2	14	1,772,412 - 1,843,247 (+)	NCBI
Rnor_6.0	14	2,789,699 - 2,860,354 (+)	NCBI
Rnor_5.0	14	2,789,914 - 2,860,569 (+)	NCBI
RGSC_v3.4	14	2,326,255 - 2,397,029 (+)	RGD
Celera	14	1,847,445 - 1,863,186 (+)	RGD

Sequence:

show sequence

CGGCCGCGCTCGGGTCCGCCTCCGACTGCGGCGCGGCGGGGCGATGTGAGTGCCATGGCGAGGA
GTGTCTGCGCGGGGGCCTGGCTGAGGAAACCCCATTACCTCCAGGCTCGCCTGTCCTACATGCG
GGTGAAGTACCTTTTCTTCTCCTGGCTGGTGGTTTTTGTTGGAAGCTGGATCCTATATGTGCAG
TATTCAACCTATACAGAGCTCTGCAGAGGGAAGGACTGTAAGAAAATCATATGTGACAAATACA
AGACCGGAGTTATTGATGGGCCTGCATGCAACAGCCTCTGTGTCACAGAAACACTGTACTTTGG
AAAATGTCTGTCCACCAAGCCCAACAACCAGATGTACTTAGGCGTCTGGGACAACCTGCCAGGT
GTCGTGAAGTGTCAAATGGAGCAAGCTCCCCATCTTGACTTTGGAACTGACCTGGAGCCAAGAA
AGGAAATCGTGCTATTTGATAAACCAACCAGGGGAACTACTGTACAGAAATTCAAAGAAATGGT
GTACAGTCTCTTCAAGGCAAAATTAGGTGACCAAGGAAACCTCTCTGAGTTGGTTAACCTCATC
CTGACAGTGGCTGATGGAGACAGAGATGGCCAGGTGTCCCTAGGAGAAGCCAAGTCAGCATGGG
CACTTCTCCAGTTGAATGAGTTTCTCTTGATGGTAATACTTCAAGATAAAGAACATACCCCCAA
ACTAATGGGATTCTGTGGTGATCTCTATGTGATGGAAAGTGTTGAATATACCTCTCTGTATGGA
ATAAGTCTTCCATGGGTTATGGAACTTTTTATCCCATCTGGGTTCAGAAGGAGCATGGATCAGT
TGTTCACACCATCATGGCCCAGAAAAGCCAAGATAGCCATAGGACTTCTAGAATTTGTAGAGGA
TGTTTTCCATGGCCCTTATGGAAACTTTCTCATGTGTGACACCAGTGCCAAAAACCTAGGATAT
AATGAGAAATATGACTTGAAAATGGTGGACATGAGGAAAATTGTGCCAGAGACAAACCTAAAGG
AACTCATCAAGGACCGCCACTGTGAGTCTGACCTGGACTGCGTCTACGGTACAGACTGCAGAAC
TAGCTGTGACCTGAGTACAATGAAGTGTACTTCAGAAGTAATACAACCGAACTTGGCAAAAGCT
TGTCAGTTACTCAAAGACTACCTACTGCATGGTGCTCCAGGCGAAATCCGGGAAGAACTAGAAA
AGCAGCTTTATTCTTGTATTGCTCTCAAGATCACAGCAAATCAAATGGAAATGGAACACTCTTT
GATACTAAATAACCTGAAGACATTATTGTGGAAGAAAATTTCCTACACAAATGACTCCTAGTAA
AATTTGGACTATTACCACTATTGAGAATCTACTTATGTTTGAGCATTTAAAAGAATGGCTTCTG
TCCCCTGGGCCTATGGAGTCGTTTTAAATGCATGTTATGACAGTGATGGCAGGTATAGAGCCAA
GAGATGTCCAAAACTCATTCCTGCCTTTTTACAAGTTCATAAGTATATTCACTGTTAACTATTT
TGACTTTAAAAAAATTAATGCTGTGAAAAGCCTCATTGCATACAGTGAGTGGTCTGTAGGTGTT
AGCCAATCCCATTGCATAGTGAGTGTTCTGTAGGTTGTCAACCTATCTATCCCATTGCTGGACA
TTGTTTGCACTGAAGCTGCTGTCTAAACAAAGACATTCATACATGGACTTACTAATGTTTTAGC
ATGGTAAAAGTTTGCACAGTAACACAAAGAATGCTACACAGGTAAACTCAAAGGACTCGTTTAT
TAAAGCTCAGTTAATATAGCATGGTTTACTGTATACTTACACATTTTACCTTCAGATGGCTCCA
CTGCTGAATGGCTTTTTAGCTTCAAGCATATATTCTACATGCAGTTACCACTGCAACTGAAATT
CATTATCCTGAAGCTCTGATAGTGTCAACAAGTGATGTACATTATCTTAGGCTGGGGATGTAGA
CCAGCAGTCAACTGTTTACCTGACACTGTAAGGCAGAGGCTACAGATGCAGACTGCCTCAGCTG
AGACAGACCAAGGAAGACTGGAATAAATCAGCAAGAGTTCTTGCTCCTTGTGGTTGAAGGGCTA
TTTCTTAAGAGGCATAAATATATCACCTAGTACTTTTTCCCACATGAACCTGATAGGCAAGGTT
TAATATTTGACCCTTTCAAGTTATTTTCTTATGTACATTCGGGTCTGGCATGTACAATAAAGAT
GAAACAAAACAAAAAACAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039092152 ⟹ XP_038948080

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	1,982,425 - 1,988,188 (+)	NCBI
mRatBN7.2	14	1,827,470 - 1,843,508 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001163927	(Get FASTA)	NCBI Sequence Viewer
	XP_038948080	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66752	(Get FASTA)	NCBI Sequence Viewer
	EDL83993	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000031951
	ENSRNOP00000031951.6
	ENSRNOP00000083362.1

RefSeq Acc Id:

NP_001163927 ⟸ NM_001170456

- UniProtKB:

B2RYE8 (UniProtKB/TrEMBL), F1LML6 (UniProtKB/TrEMBL), A0A8I5ZWT8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MARSVCAGAWLRKPHYLQARLSYMRVKYLFFSWLVVFVGSWILYVQYSTYTELCRGKDCKKIIC
DKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGVWDNLPGVVKCQMEQAPHLDFGTDL
EPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDRDGQVSLGEAK
SAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVMELFIPSGFRRS
MDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNEKYDLKMVDMRKIVPET
NLKELIKDRHCESDLDCVYGTDCRTSCDLSTMKCTSEVIQPNLAKACQLLKDYLLHGAPGEIRE
ELEKQLYSCIALKITANQMEMEHSLILNNLKTLLWKKISYTNDS

hide sequence

RefSeq Acc Id:

ENSRNOP00000031951 ⟸ ENSRNOT00000030479

RefSeq Acc Id:	XP_038948080 ⟸ XM_039092152
- Peptide Label:	isoform X1
- UniProtKB:	A6KPH2 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000083362 ⟸ ENSRNOT00000112934

Protein Domains

FAM69 N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LML6-F1-model_v2	AlphaFold	F1LML6	1-428	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308581	AgrOrtholog
BioCyc Gene	G2FUF-16639	BioCyc
Ensembl Genes	ENSRNOG00000023533	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000030479	ENTREZGENE
	ENSRNOT00000030479.7	UniProtKB/TrEMBL
	ENSRNOT00000112934.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5621368	IMAGE-MGC_LOAD
InterPro	FAM69_N	UniProtKB/TrEMBL
	Uncharacterised_FAM69_C	UniProtKB/TrEMBL
KEGG Report	rno:360906	UniProtKB/TrEMBL
MGC_CLONE	MGC:188491	IMAGE-MGC_LOAD
NCBI Gene	360906	ENTREZGENE
PANTHER	DIVERGENT PROTEIN KINASE DOMAIN 1A	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	PIP49_C	UniProtKB/TrEMBL
	PIP49_N	UniProtKB/TrEMBL
PhenoGen	Dipk1a	PhenoGen
RatGTEx	ENSRNOG00000023533	RatGTEx
SMART	PIP49_N	UniProtKB/TrEMBL
UniProt	A0A8I5ZWT8	ENTREZGENE, UniProtKB/TrEMBL
	A6KPH2	ENTREZGENE, UniProtKB/TrEMBL
	B2RYE8	ENTREZGENE, UniProtKB/TrEMBL
	F1LML6	ENTREZGENE
UniProt Secondary	F1LML6	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-10-08	Dipk1a	divergent protein kinase domain 1A	Fam69a	family with sequence similarity 69, member A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Fam69a	family with sequence similarity 69, member A	RGD1308581_predicted	similar to RIKEN cDNA 2900024C23 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1308581_predicted	similar to RIKEN cDNA 2900024C23 (predicted)	LOC360906_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC360906_predicted	similar to RIKEN cDNA 2900024C23 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar