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Gene Ontology Annotations
Gene Ontology AnnotationsBiological Process Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | gene silencing | | ISO | RGD:1623920 | 1624291 | MGI:MGI:3623309|MGI:MGI:3056522 | RGD | MGI:MGI:4849597 PMID:20808952 | histone H3-K4 methylation | | ISO | RGD:1605411 | 1624291 | PMID:17166833 | RGD | PMID:17166833 | histone H3-K4 trimethylation | | ISO | RGD:1623920 | 1624291 | MGI:MGI:3623309|MGI:MGI:2176052 | RGD | MGI:MGI:4849597 PMID:20808952 | histone lysine methylation | | ISO | RGD:1623920 | 1624291 | MGI:MGI:3623309|MGI:MGI:3056522 | RGD | MGI:MGI:4849597 PMID:20808952 | oocyte differentiation | | ISO | RGD:1623920 | 1624291 | MGI:MGI:3623309|MGI:MGI:2176052 | RGD | MGI:MGI:4849597 PMID:20808952 | ovarian follicle development | | ISO | RGD:1623920 | 1624291 | MGI:MGI:3623309|MGI:MGI:2176052 | RGD | MGI:MGI:4849597 PMID:20808952 | ovulation | | ISO | RGD:1623920 | 1624291 | MGI:MGI:3623309|MGI:MGI:3056522 | RGD | MGI:MGI:4849597 PMID:20808952 | regulation of histone H3-K4 methylation | | ISO | RGD:1623920 | 1624291 | MGI:MGI:3623309|MGI:MGI:2176052 | RGD | MGI:MGI:4849597 PMID:20808952 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Lysine degradation |
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
References - curated| 1. |
Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology |
| 2. |
RGD automated data pipeline |
| 3. |
RGD automated import pipeline for gene-chemical interactions |
RGD Disease Portals| Mll4 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Mll4 (Rattus norvegicus) |
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| MLL4 (Homo sapiens) |
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| Wbp7 (Mus musculus) |
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Position Markers| MARC_2763-2764:991933378:3 |
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| ksks195 |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | XM_002728730 | (Get FASTA) | Search GEO for Microarray Profiles |
| XM_341829 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | XM_002728730 | ||||||||||
| RefSeq Status: | |||||||||||
| Type: | CODING | ||||||||||
| Protein Acc Id: | XP_002728776 | ||||||||||
| Position: |
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| RefSeq Acc Id: | XM_341829 | ||||||||||
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| Type: | CODING | ||||||||||
| Protein Acc Id: | XP_341830 | ||||||||||
| Peptide Label: | isoform 2 | ||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | XP_002728776 | (Get FASTA) |
| XP_341830 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000020961 | UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000041928 | UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000046359 | UniProtKB/TrEMBL |
| Entrez Gene | 361543 | ENTREZGENE |
| Gene3D-CATH | Znf_RING/FYVE/PHD | UniProtKB/TrEMBL |
| HomoloGene Group ID | 22838 | ENTREZGENE |
| InterPro | AT_hook_DNA-bd_motif | UniProtKB/TrEMBL |
| FYrich_C | UniProtKB/TrEMBL | |
| FYrich_N | UniProtKB/TrEMBL | |
| Histone-lysine_MeTfrase | UniProtKB/TrEMBL | |
| Post-SET_dom | UniProtKB/TrEMBL | |
| SET_dom | UniProtKB/TrEMBL | |
| Znf_CXXC | UniProtKB/TrEMBL | |
| Znf_FYVE_PHD | UniProtKB/TrEMBL | |
| Znf_PHD | UniProtKB/TrEMBL | |
| Znf_PHD-finger | UniProtKB/TrEMBL | |
| Znf_RING/FYVE/PHD | UniProtKB/TrEMBL | |
| IPI | IPI00958760 | UniProtKB/TrEMBL |
| PANTHER | PTHR22884:SF10 | UniProtKB/TrEMBL |
| Pfam | FYRC | UniProtKB/TrEMBL |
| FYRN | UniProtKB/TrEMBL | |
| PHD | UniProtKB/TrEMBL | |
| SET | UniProtKB/TrEMBL | |
| zf-CXXC | UniProtKB/TrEMBL | |
| PROSITE | FYRC | UniProtKB/TrEMBL |
| FYRN | UniProtKB/TrEMBL | |
| POST_SET | UniProtKB/TrEMBL | |
| SET | UniProtKB/TrEMBL | |
| ZF_CXXC | UniProtKB/TrEMBL | |
| ZF_PHD_2 | UniProtKB/TrEMBL | |
| SMART | AT_hook | UniProtKB/TrEMBL |
| FYRC | UniProtKB/TrEMBL | |
| FYRN | UniProtKB/TrEMBL | |
| PHD | UniProtKB/TrEMBL | |
| PostSET | UniProtKB/TrEMBL | |
| SET | UniProtKB/TrEMBL | |
| Superfamily-SCOP | FYVE_PHD_ZnF | UniProtKB/TrEMBL |
| UniProt | D3ZKG0_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2008-10-23 | Mll4 | myeloid/lymphoid or mixed-lineage leukemia 4 | Wbp7 | WW domain binding protein 7 | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2008-02-26 | Wbp7 | WW domain binding protein 7 | RGD1308331_predicted | similar to Trithorax homolog 2 (Mixed lineage leukemia gene homolog 2 protein) (predicted) | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2005-01-20 | RGD1308331_predicted | similar to Trithorax homolog 2 (Mixed lineage leukemia gene homolog 2 protein) (predicted) | LOC361543_predicted | Symbol and Name status set to approved | 12407 | APPROVED | |
| 2005-01-12 | LOC361543_predicted | similar to Trithorax homolog 2 (Mixed lineage leukemia gene homolog 2 protein) (predicted) | Symbol and Name status set to provisional | 1724 | PROVISIONAL |
| More on Mll4 | |
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Entrez Gene |
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Ensembl Gene |
![]() | Genome Browser |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 1308331 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




