Phf13 (PHD finger protein 13) - Rat Genome Database

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Gene: Phf13 (PHD finger protein 13) Rattus norvegicus
Analyze
Symbol: Phf13
Name: PHD finger protein 13
RGD ID: 1308145
Description: Predicted to enable chromatin binding activity; chromatin-protein adaptor activity; and methylated histone binding activity. Predicted to be involved in mitotic chromosome condensation and regulation of DNA repair. Predicted to be active in nucleus. Orthologous to human PHF13 (PHD finger protein 13); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC313742
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85167,777,303 - 167,784,077 (-)NCBIGRCr8
mRatBN7.25162,494,574 - 162,501,350 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,494,573 - 162,501,350 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5165,197,659 - 165,204,444 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,018,507 - 167,025,304 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05166,980,706 - 166,987,503 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,161,412 - 169,167,831 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,161,412 - 169,167,831 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05172,719,997 - 172,726,441 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,215,834 - 169,222,883 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15169,226,020 - 169,234,653 (-)NCBI
Celera5160,727,367 - 160,734,068 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19638409  


Genomics

Comparative Map Data
Phf13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85167,777,303 - 167,784,077 (-)NCBIGRCr8
mRatBN7.25162,494,574 - 162,501,350 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,494,573 - 162,501,350 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5165,197,659 - 165,204,444 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,018,507 - 167,025,304 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05166,980,706 - 166,987,503 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,161,412 - 169,167,831 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,161,412 - 169,167,831 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05172,719,997 - 172,726,441 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,215,834 - 169,222,883 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15169,226,020 - 169,234,653 (-)NCBI
Celera5160,727,367 - 160,734,068 (-)NCBICelera
Cytogenetic Map5q36NCBI
PHF13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816,613,731 - 6,624,030 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16,613,731 - 6,624,030 (+)EnsemblGRCh38hg38GRCh38
GRCh3716,673,791 - 6,684,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,596,332 - 6,606,643 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416,608,010 - 6,618,322NCBI
Celera15,787,615 - 5,797,954 (+)NCBICelera
Cytogenetic Map1p36.31NCBI
HuRef15,821,676 - 5,831,583 (+)NCBIHuRef
CHM1_116,662,474 - 6,672,816 (+)NCBICHM1_1
T2T-CHM13v2.016,139,395 - 6,149,694 (+)NCBIT2T-CHM13v2.0
Phf13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394152,074,088 - 152,080,636 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4152,074,090 - 152,080,715 (-)EnsemblGRCm39 Ensembl
GRCm384151,989,631 - 151,996,179 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4151,989,633 - 151,996,258 (-)EnsemblGRCm38mm10GRCm38
MGSCv374151,363,740 - 151,370,288 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364150,833,433 - 150,836,362 (-)NCBIMGSCv36mm8
Celera4154,274,605 - 154,281,210 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map482.81NCBI
Phf13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554866,017,748 - 6,025,614 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554866,018,614 - 6,025,473 (-)NCBIChiLan1.0ChiLan1.0
PHF13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,601,412 - 221,613,628 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,243,605 - 220,254,236 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v015,377,740 - 5,388,024 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.116,631,620 - 6,639,972 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16,631,621 - 6,639,972 (+)Ensemblpanpan1.1panPan2
PHF13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1560,434,218 - 60,441,930 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl560,433,328 - 60,439,672 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha560,443,828 - 60,451,377 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0560,650,231 - 60,657,779 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1560,649,517 - 60,657,077 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0560,515,731 - 60,523,286 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0560,918,173 - 60,925,716 (+)NCBIUU_Cfam_GSD_1.0
Phf13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505830,881,413 - 30,886,984 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366231,366,401 - 1,372,222 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366231,364,422 - 1,372,226 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHF13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl667,445,978 - 67,454,189 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1667,445,960 - 67,452,144 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2662,388,142 - 62,394,203 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHF13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120125,122,118 - 125,133,013 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20125,121,886 - 125,132,966 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605429,165,887 - 29,177,029 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phf13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248184,913,287 - 4,921,118 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248184,913,209 - 4,921,093 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Phf13
17 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:833
Count of miRNA genes:324
Interacting mature miRNAs:423
Transcripts:ENSRNOT00000012407
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

Markers in Region
RH143852  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25162,501,020 - 162,501,241 (+)MAPPERmRatBN7.2
Rnor_6.05169,167,502 - 169,167,722NCBIRnor6.0
Rnor_5.05172,726,112 - 172,726,332UniSTSRnor5.0
RGSC_v3.45169,222,554 - 169,222,774UniSTSRGSC3.4
Celera5160,733,739 - 160,733,959UniSTS
RH 3.4 Map51143.3UniSTS
Cytogenetic Map5q36UniSTS
UniSTS:496742  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25162,496,500 - 162,496,595 (+)MAPPERmRatBN7.2
Rnor_6.05169,163,339 - 169,163,433NCBIRnor6.0
Rnor_5.05172,721,924 - 172,722,018UniSTSRnor5.0
RGSC_v3.45169,217,761 - 169,217,855UniSTSRGSC3.4
Celera5160,729,294 - 160,729,388UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 20 6 6 6 56 20 38 1
Low 3 23 51 35 19 35 8 11 18 15 3 10 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000012407   ⟹   ENSRNOP00000012407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5162,494,574 - 162,501,350 (-)Ensembl
Rnor_6.0 Ensembl5169,161,412 - 169,167,831 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118274   ⟹   ENSRNOP00000079267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5162,494,573 - 162,500,165 (-)Ensembl
RefSeq Acc Id: NM_001107995   ⟹   NP_001101465
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85167,777,303 - 167,784,077 (-)NCBI
mRatBN7.25162,494,574 - 162,501,350 (-)NCBI
Rnor_6.05169,161,412 - 169,167,831 (-)NCBI
Rnor_5.05172,719,997 - 172,726,441 (-)NCBI
RGSC_v3.45169,215,834 - 169,222,883 (-)RGD
Celera5160,727,367 - 160,734,068 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001101465 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL81210 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012407
  ENSRNOP00000012407.4
  ENSRNOP00000079267.1
RefSeq Acc Id: NP_001101465   ⟸   NM_001107995
- UniProtKB: D3ZG56 (UniProtKB/TrEMBL),   A6IUF9 (UniProtKB/TrEMBL),   A0A8I5ZN36 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012407   ⟸   ENSRNOT00000012407
RefSeq Acc Id: ENSRNOP00000079267   ⟸   ENSRNOT00000118274
Protein Domains
Zinc finger PHD-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZG56-F1-model_v2 AlphaFold D3ZG56 1-296 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694294
Promoter ID:EPDNEW_R4817
Type:multiple initiation site
Name:Phf13_1
Description:PHD finger protein 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05169,167,847 - 169,167,907EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308145 AgrOrtholog
BioCyc Gene G2FUF-39030 BioCyc
Ensembl Genes ENSRNOG00000009046 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012407 ENTREZGENE
  ENSRNOT00000012407.6 UniProtKB/TrEMBL
  ENSRNOT00000118274.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro PHD_PHF13 UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:313742 UniProtKB/TrEMBL
NCBI Gene 313742 ENTREZGENE
PANTHER PHD FINGER PROTEIN 13 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam PHD_5 UniProtKB/TrEMBL
PhenoGen Phf13 PhenoGen
RatGTEx ENSRNOG00000009046 RatGTEx
SMART PHD UniProtKB/TrEMBL
Superfamily-SCOP FYVE_PHD_ZnF UniProtKB/TrEMBL
UniProt A0A8I5ZN36 ENTREZGENE, UniProtKB/TrEMBL
  A6IUF9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZG56 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Phf13  PHD finger protein 13   Phf13_predicted  PHD finger protein 13 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Phf13_predicted  PHD finger protein 13 (predicted)      Symbol and Name status set to approved 70820 APPROVED