Rbm7 (RNA binding motif protein 7)

Gene: Rbm7 (RNA binding motif protein 7) Rattus norvegicus

Analyze

Symbol:

Rbm7

Name:

RNA binding motif protein 7

RGD ID:

1308017

Description:

Predicted to enable 14-3-3 protein binding activity; pre-mRNA intronic binding activity; and snRNA binding activity. Predicted to be involved in snRNA catabolic process. Predicted to be located in nucleoplasm. Orthologous to human RBM7 (RNA binding motif protein 7); INTERACTS WITH 2,4-dinitrotoluene; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC315634; RNA-binding protein 7

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RBM7 (RNA binding motif protein 7)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Rbm7 (RNA binding motif protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rbm7 (RNA binding motif protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RBM7 (RNA binding motif protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RBM7 (RNA binding motif protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rbm7 (RNA binding motif protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RBM7 (RNA binding motif protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RBM7 (RNA binding motif protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rbm7 (RNA binding motif protein 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RBM7 (RNA binding motif protein 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rbm7 (RNA binding motif protein 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rbm7 (RNA binding motif protein 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG11454	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Xenopus tropicalis (tropical clawed frog):	rbm7	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	57,728,413 - 57,734,833 (-)	NCBI		GRCr8
mRatBN7.2	8	48,831,894 - 48,838,399 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	48,831,894 - 48,838,411 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	54,332,523 - 54,338,945 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	52,611,355 - 52,617,777 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	50,475,624 - 50,482,046 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	52,823,094 - 52,828,134 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	52,823,096 - 52,828,134 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	51,415,945 - 51,421,517 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	51,769,353 - 51,774,447 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	51,788,710 - 51,794,301 (-)	NCBI
Celera	8	48,391,464 - 48,396,562 (-)	NCBI		Celera
Cytogenetic Map	8	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chromosome 11, Partial Trisomy 11q (ISO)

genetic disease (ISO)

intellectual disability (ISO)

lung non-small cell carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,4-dinitrotoluene (EXP)

3',5'-cyclic UMP (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP)

caffeine (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

dicrotophos (ISO)

diethylstilbestrol (ISO)

doxorubicin (ISO)

fenvalerate (EXP)

flutamide (EXP)

formaldehyde (ISO)

FR900359 (ISO)

gefitinib (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

phenobarbital (ISO)

silver atom (ISO)

silver(0) (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

thimerosal (ISO)

thioacetamide (EXP)

trichostatin A (ISO)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of alternative mRNA splicing, via spliceosome (IEA)

snRNA catabolic process (ISO)

Cellular Component

nucleolus (ISO)

nucleoplasm (IEA,ISO)

nucleus (ISO)

Molecular Function

14-3-3 protein binding (ISO)

pre-mRNA intronic binding (ISO)

protein binding (ISO)

RNA binding (ISO)

single-stranded RNA binding (IEA)

snRNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:16263084	PMID:21855801	PMID:22658674	PMID:22681889	PMID:25189701	PMID:25525152	PMID:25578728	PMID:25852104	PMID:30824372

Genomics

Comparative Map Data

Rbm7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	57,728,413 - 57,734,833 (-)	NCBI		GRCr8
mRatBN7.2	8	48,831,894 - 48,838,399 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	48,831,894 - 48,838,411 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	54,332,523 - 54,338,945 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	52,611,355 - 52,617,777 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	50,475,624 - 50,482,046 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	52,823,094 - 52,828,134 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	52,823,096 - 52,828,134 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	51,415,945 - 51,421,517 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	51,769,353 - 51,774,447 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	51,788,710 - 51,794,301 (-)	NCBI
Celera	8	48,391,464 - 48,396,562 (-)	NCBI		Celera
Cytogenetic Map	8	q23	NCBI

RBM7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	114,400,666 - 114,410,607 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	114,400,030 - 114,414,203 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	114,271,388 - 114,281,329 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	113,776,594 - 113,784,845 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	113,776,593 - 113,784,843	NCBI
Celera	11	111,424,330 - 111,432,572 (+)	NCBI		Celera
Cytogenetic Map	11	q23.2	NCBI
HuRef	11	110,199,984 - 110,208,225 (+)	NCBI		HuRef
CHM1_1	11	114,155,373 - 114,163,624 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	114,411,085 - 114,421,025 (+)	NCBI		T2T-CHM13v2.0

Rbm7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	48,399,997 - 48,406,630 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	48,400,001 - 48,406,599 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	48,488,697 - 48,495,330 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	48,488,701 - 48,495,299 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	48,296,814 - 48,303,410 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	48,240,676 - 48,247,272 (-)	NCBI		MGSCv36	mm8
Celera	9	45,785,707 - 45,792,303 (-)	NCBI		Celera
Cytogenetic Map	9	A5.3	NCBI
cM Map	9	26.43	NCBI

Rbm7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	15,996,206 - 16,006,525 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	15,996,206 - 16,004,177 (+)	NCBI	ChiLan1.0	ChiLan1.0

RBM7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	115,138,913 - 115,147,776 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	116,233,389 - 116,241,665 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	109,274,678 - 109,284,568 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	113,117,771 - 113,127,613 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	113,117,771 - 113,131,348 (+)	Ensembl	panpan1.1		panPan2

RBM7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	18,950,393 - 18,959,844 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	18,875,727 - 18,885,227 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	18,897,961 - 18,907,684 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	18,897,968 - 18,907,688 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	19,036,532 - 19,046,065 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	18,937,823 - 18,947,357 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	18,982,529 - 18,992,069 (-)	NCBI		UU_Cfam_GSD_1.0

Rbm7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	96,458,342 - 96,465,716 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936612	240,340 - 247,197 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936612	239,618 - 247,277 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RBM7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	41,947,589 - 41,956,210 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	41,947,081 - 41,955,683 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	46,923,883 - 46,932,024 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RBM7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	105,806,156 - 105,815,518 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	105,806,228 - 105,816,356 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	20,227,547 - 20,236,882 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rbm7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624784	9,878,068 - 9,884,905 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624784	9,878,068 - 9,885,874 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rbm7
25 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	241
Count of miRNA genes:	167
Interacting mature miRNAs:	192
Transcripts:	ENSRNOT00000007736
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	4705810	49705810	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	4705810	49705810	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	4705810	49705810	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	7670578	52670578	Rat
1354595	Despr4	Despair related QTL 4	2.16	0.0036	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	8	7688955	52688955	Rat
1354627	Despr14	Despair related QTL 14		0.0056	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	7688955	52688955	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	8736635	53736635	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	8736635	53736635	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	9712220	53356647	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
1558646	Swd5	Spike wave discharge measurement QTL 5	3.45	0.00036	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	8	14906751	59906751	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	16290444	61290444	Rat
631271	Lecl1	Lens clarity QTL 1		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	8	18984168	84531599	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	19331152	93965294	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	22662330	67662330	Rat
2303564	Gluco43	Glucose level QTL 43	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	26130187	71130187	Rat
2303572	Insul13	Insulin level QTL 13	2		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	8	26130187	71130187	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	27205715	54998217	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	27205715	99103503	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	27205715	99103503	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	27205715	99103503	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	28242912	53961020	Rat
1300146	Rf17	Renal function QTL 17	2.9		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	8	28242912	73242912	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	28242912	99525068	Rat
2302278	Gluco36	Glucose level QTL 36	4.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	29502665	50095447	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	29502665	70386295	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	30188867	94457446	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	58482492	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	30848154	61290444	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	30848154	61290444	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	30848154	61290444	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	30848154	82460899	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	30848154	82460899	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	30848154	82460899	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	30848154	82460899	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	30848154	101699754	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	30848154	101699754	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	30848154	101699754	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30848259	105647037	Rat
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30856404	75856404	Rat
1582222	Epfw2	Epididymal fat weight QTL 2	3.2	0.0005	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	8	31737729	76737729	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	35551938	80551938	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	35582032	80582032	Rat
1331838	Niddm61	Non-insulin dependent diabetes mellitus QTL 61	3.53	0.0004	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	36469535	99083736	Rat
737824	Hcar10	Hepatocarcinoma resistance QTL 10	2.9		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	8	40713066	82925667	Rat
1358906	Bp253	Blood pressure QTL 253	4	0.0004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	40713066	93965294	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
1331769	Rf39	Renal function QTL 39	3.871		urine output (VT:0003620)	timed urine volume (CMO:0000260)	8	41866876	75097878	Rat
1298079	Activ2	Activity QTL 2	9.5	0.000001	voluntary movement trait (VT:0003491)	rearing measurement (CMO:0001515)	8	41866876	86866876	Rat
631216	Stl9	Serum triglyceride level QTL 9	4.71	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	8	41867010	70386132	Rat
5684993	Bmd84	Bone mineral density QTL 84	4.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	8	42692684	50095447	Rat
70161	Bp62	Blood pressure QTL 62	2.9	0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	42692684	90165460	Rat
12879882	Am8	Aortic mass QTL 8		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	43296169	98968765	Rat
12879878	Bw183	Body weight QTL 183		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	43296169	98968765	Rat
12879879	Cm99	Cardiac mass QTL 99		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	43296169	98968765	Rat
12879880	Cm100	Cardiac mass QTL 100		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	43296169	98968765	Rat
12879881	Cm101	Cardiac mass QTL 101		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	8	43296169	98968765	Rat
12879883	Kidm65	Kidney mass QTL 65		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	43296169	98968765	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	46531639	119088626	Rat
1331837	Bw23	Body weight QTL 23	4.19	0.00007	body mass (VT:0001259)	body weight (CMO:0000012)	8	46531722	99083736	Rat
1582229	Stl20	Serum triglyceride level QTL 20	3.2	0.0033	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	8	48630131	49147989	Rat

Markers in Region

RH131698

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	48,839,395 - 48,839,576 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	52,830,036 - 52,830,216	NCBI	Rnor6.0
Rnor_5.0	8	51,423,419 - 51,423,599	UniSTS	Rnor5.0
RGSC_v3.4	8	51,776,349 - 51,776,529	UniSTS	RGSC3.4
Celera	8	48,398,464 - 48,398,644	UniSTS
RH 3.4 Map	8	513.6	UniSTS
Cytogenetic Map	8	q23	UniSTS

RH132945

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	48,832,641 - 48,832,822 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	52,823,340 - 52,823,520	NCBI	Rnor6.0
Rnor_5.0	8	51,416,191 - 51,416,371	UniSTS	Rnor5.0
RGSC_v3.4	8	51,769,599 - 51,769,779	UniSTS	RGSC3.4
Celera	8	48,391,710 - 48,391,890	UniSTS
RH 3.4 Map	8	514.1	UniSTS
Cytogenetic Map	8	q23	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	41	57	41	19	41	8	9	74	35	41	11	8
Low		2						2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108143	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001401005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063265439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213333	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229819	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000007736 ⟹ ENSRNOP00000007736

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	48,831,894 - 48,838,312 (-)	Ensembl
Rnor_6.0 Ensembl	8	52,823,096 - 52,828,134 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000110100 ⟹ ENSRNOP00000076794

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	48,834,026 - 48,838,344 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000111739 ⟹ ENSRNOP00000089745

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	48,831,894 - 48,838,411 (-)	Ensembl

RefSeq Acc Id:

NM_001108143 ⟹ NP_001101613

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	57,728,915 - 57,734,013 (-)	NCBI
mRatBN7.2	8	48,832,396 - 48,837,494 (-)	NCBI
Rnor_6.0	8	52,823,094 - 52,828,134 (-)	NCBI
Rnor_5.0	8	51,415,945 - 51,421,517 (-)	NCBI
RGSC_v3.4	8	51,769,353 - 51,774,447 (-)	RGD
Celera	8	48,391,464 - 48,396,562 (-)	RGD

Sequence:

show sequence

TCTCGATATCAAGTCGGAACTAGAATAATTTACTAAAAGGGAAGTAAGTAGATGTCCAGCCCTT
GTCGGGACATTTTATTTTTGATGAGGTGTTGATTATATACCTTTTGTTTACAACTTGTGTTCTC
TTCTTTATAGTATTTGAGACAGAGAGACAGTCTCTATAGCCTTGGTAGCCCTGGGACTCCGAGG
CTGACTTTGAGCTGGTCCTCCTGCCTGCATCCCTTGACATCTGACAATACAGGCTGGGCCAGTA
ATAAAGGTGAAAATCCCAAAAGATAAAGATGGCAAACTGAAGCAGTTTGCATTTGTGAATTTCA
AACACGAAGTGTCTGTTCCCTACGCCATGAATCTTCTCAATGGAATCAAACTTTTCGGGAGGCC
TATCAAAATTCAGTTTAGATCAGGAAGTAGTCACCTCTCTCAGGACGCCAGTACGTCATATCCC
CAGCACCATATGGGAAACTTAAGCCCTACGTCCACATCTCCTAACAGCTATGAAAGGACGGTGG
GTAACGTGACTCCGCCAGCACAGATGGTCCAGAGGTCCTTTTCAACTCCAGAAGATTATCAGCG
GCAAGCAGTGATGAACAGTGTTTTCAGACAGATGTCATATGTTGGGAAATTTGGTTCTCCACAT
GCAGATCAGTTGGGATTTTCACCGTCAGTTCAACCACATGGTCACACCTTTAACCAGTCTTCCA
GCTCCCAGTGGCGCCAAGATGCGGTGTCATCACAGCGTAAAAGACAGAATTCTCACCCCTACCT
AGCAGATAGACACTATAGCCGTGAGCAGCGCTACTCTGATCATGGGTCTGATTATCATTACAGA
GGAGGCCGAGAGGATTTCTACTATGACGACAGGAATCATGATGGCTGGAGCCATGATTATGATA
ACAGAAGGGACAGTAGTAGAGGTGGAAAGTGGCCCTCATCCCGACACTAACAAGCATTCCAAGG
ACATTGTTTACAGGGCCATTTTCGGTCCTTTTAACTAAGTTGTTGCAGAAATATTTCTAAAAAC
TGTACAGAGTAATCCCACAATTTTCCACCTGTCTTTGAAAAAAATGTTTTTAAACCTAGTAACA
GTTCATAGAGAACTGAGAACCGTGGCTCCTCGTGTGCTGCTTTAATCACCTGACCTCAGGGTTC
TGATGAGGAAGGTTTATACAAAAGAGTGAGCACCATTCTGGTCATTTCAGACAGTCTGGGAAAG
ATGAGTATGTAGATGGGTTGTATTATAAAGCAAATATTTTACTTATGTCACCTTTTGTGTTGCA
AGAAATATCTTGGTAATGAATCAACTTGGTGTATATAATAGGAAACATCTAAGTTGGTAGTCTG
AAATGGCTGTCTGCATTTTGTTAATAAATGAGAAAATGGAAAAAAAAAAAAAAAAAAAAAAAAA
AAA

hide sequence

RefSeq Acc Id:

NM_001401005 ⟹ NP_001387934

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	57,728,413 - 57,734,833 (-)	NCBI
mRatBN7.2	8	48,831,894 - 48,838,314 (-)	NCBI

RefSeq Acc Id:

XM_039081442 ⟹ XP_038937370

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	57,729,607 - 57,734,813 (-)	NCBI
mRatBN7.2	8	48,833,088 - 48,838,399 (-)	NCBI

RefSeq Acc Id:

XM_063265439 ⟹ XP_063121509

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	57,733,558 - 57,734,769 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101613	(Get FASTA)	NCBI Sequence Viewer
	NP_001387934	(Get FASTA)	NCBI Sequence Viewer
	XP_038937370	(Get FASTA)	NCBI Sequence Viewer
	XP_063121509	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66987	(Get FASTA)	NCBI Sequence Viewer
	EDL95423	(Get FASTA)	NCBI Sequence Viewer
	EDL95424	(Get FASTA)	NCBI Sequence Viewer
	EDL95425	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007736.7
	ENSRNOP00000076794.1
	ENSRNOP00000089745.1

RefSeq Acc Id:	NP_001101613 ⟸ NM_001108143
- Peptide Label:	isoform 2
- UniProtKB:	B2RZ14 (UniProtKB/TrEMBL), F1M8F0 (UniProtKB/TrEMBL), A6J4A1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNLLNGIKLFGRPIKIQFRSGSSHLSQDASTSYPQHHMGNLSPTSTSPNSYERTVGNVTPPAQM VQRSFSTPEDYQRQAVMNSVFRQMSYVGKFGSPHADQLGFSPSVQPHGHTFNQSSSSQWRQDAV SSQRKRQNSHPYLADRHYSREQRYSDHGSDYHYRGGREDFYYDDRNHDGWSHDYDNRRDSSRGG KWPSSRH hide sequence

RefSeq Acc Id:

ENSRNOP00000007736 ⟸ ENSRNOT00000007736

RefSeq Acc Id:	XP_038937370 ⟸ XM_039081442
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5XVE7 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000076794 ⟸ ENSRNOT00000110100

RefSeq Acc Id:

ENSRNOP00000089745 ⟸ ENSRNOT00000111739

RefSeq Acc Id:	NP_001387934 ⟸ NM_001401005
- Peptide Label:	isoform 1

RefSeq Acc Id:	XP_063121509 ⟸ XM_063265439
- Peptide Label:	isoform X1

Protein Domains

RRM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M8F0-F1-model_v2	AlphaFold	F1M8F0	1-198	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308017	AgrOrtholog
BioCyc Gene	G2FUF-30602	BioCyc
Ensembl Genes	ENSRNOG00000005710	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000007736.8	UniProtKB/TrEMBL
	ENSRNOT00000110100.1	UniProtKB/TrEMBL
	ENSRNOT00000111739.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7442233	IMAGE-MGC_LOAD
InterPro	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RBM7_RRM	UniProtKB/TrEMBL
	RRM_dom	UniProtKB/TrEMBL
KEGG Report	rno:315634	UniProtKB/TrEMBL
MGC_CLONE	MGC:189117	IMAGE-MGC_LOAD
NCBI Gene	315634	ENTREZGENE
PANTHER	RNA BINDING MOTIF RBM PROTEIN -RELATED	UniProtKB/TrEMBL
	RNA-BINDING PROTEIN 7	UniProtKB/TrEMBL
Pfam	RRM_1	UniProtKB/TrEMBL
PhenoGen	Rbm7	PhenoGen
PROSITE	RRM	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000005710	RatGTEx
SMART	RRM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/TrEMBL
UniProt	A0A8I5XVE7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ACC7_RAT	UniProtKB/TrEMBL
	A6J4A0_RAT	UniProtKB/TrEMBL
	A6J4A1	ENTREZGENE, UniProtKB/TrEMBL
	B2RZ14	ENTREZGENE, UniProtKB/TrEMBL
	F1M8F0	ENTREZGENE
UniProt Secondary	F1M8F0	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Rbm7	RNA binding motif protein 7	Rbm7_predicted	RNA binding motif protein 7 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Rbm7_predicted	RNA binding motif protein 7 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD