Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | endometriosis | | ISO | MED16 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:22138541 | |
|
Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | endometriosis | | ISO | MED16 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:22138541 | |
|
|
|
|
|
|
|
|
|
|
# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
3. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
4. | The Mediator complex and transcription regulation. | Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3. |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
6. | Comprehensive gene review and curation | RGD comprehensive gene curation |
PMID:10198638 | PMID:11867769 | PMID:12093747 | PMID:12218053 | PMID:15340084 | PMID:19946888 | PMID:20508642 |
Med16 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MED16 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Med16 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Med16 (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MED16 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MED16 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Med16 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MED16 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
MED16 (Chlorocebus sabaeus - green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Med16 (Heterocephalus glaber - naked mole-rat) |
|
.
Variants in Med16
27 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH128461 |
|
||||||||||||||||||||||||||||||||||||||||
BE118278 |
|
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 35 | 25 | 25 | 3 | 25 | 3 | 66 | 27 | 36 | 3 | ||
Low | 8 | 32 | 16 | 16 | 16 | 8 | 8 | 8 | 8 | 5 | 8 | 8 | |
Below cutoff |
RefSeq Acc Id: | ENSRNOT00000015257 ⟹ ENSRNOP00000015257 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000080089 ⟹ ENSRNOP00000072279 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000093264 ⟹ ENSRNOP00000076087 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000093524 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000093620 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | NM_001106768 ⟹ NP_001100238 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
|
||||||||||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_006240861 ⟹ XP_006240923 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_006240862 ⟹ XP_006240924 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_006240864 ⟹ XP_006240926 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_006240865 ⟹ XP_006240927 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_006240866 ⟹ XP_006240928 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_039078637 ⟹ XP_038934565 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_039078640 ⟹ XP_038934568 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_039078641 ⟹ XP_038934569 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | XM_063263164 ⟹ XP_063119234 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063263165 ⟹ XP_063119235 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063263166 ⟹ XP_063119236 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063263167 ⟹ XP_063119237 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063263168 ⟹ XP_063119238 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | XM_063263169 ⟹ XP_063119239 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | NP_001100238 ⟸ NM_001106768 |
- UniProtKB: | A6K8V2 (UniProtKB/TrEMBL), D3ZHA9 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006240923 ⟸ XM_006240861 |
- Peptide Label: | isoform X3 |
- UniProtKB: | D3ZHA9 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006240924 ⟸ XM_006240862 |
- Peptide Label: | isoform X4 |
- UniProtKB: | D3ZHA9 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006240926 ⟸ XM_006240864 |
- Peptide Label: | isoform X6 |
- UniProtKB: | D3ZHA9 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006240927 ⟸ XM_006240865 |
- Peptide Label: | isoform X7 |
- UniProtKB: | A0A0G2K2K5 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006240928 ⟸ XM_006240866 |
- Peptide Label: | isoform X7 |
- UniProtKB: | A0A0G2K2K5 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000072279 ⟸ ENSRNOT00000080089 |
RefSeq Acc Id: | ENSRNOP00000076087 ⟸ ENSRNOT00000093264 |
RefSeq Acc Id: | ENSRNOP00000015257 ⟸ ENSRNOT00000015257 |
RefSeq Acc Id: | XP_038934569 ⟸ XM_039078641 |
- Peptide Label: | isoform X11 |
RefSeq Acc Id: | XP_038934565 ⟸ XM_039078637 |
- Peptide Label: | isoform X2 |
- UniProtKB: | D3ZHA9 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038934568 ⟸ XM_039078640 |
- Peptide Label: | isoform X10 |
RefSeq Acc Id: | XP_063119235 ⟸ XM_063263165 |
- Peptide Label: | isoform X5 |
RefSeq Acc Id: | XP_063119237 ⟸ XM_063263167 |
- Peptide Label: | isoform X8 |
RefSeq Acc Id: | XP_063119238 ⟸ XM_063263168 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063119236 ⟸ XM_063263166 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_063119234 ⟸ XM_063263164 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063119239 ⟸ XM_063263169 |
- Peptide Label: | isoform X9 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-D3ZHA9-F1-model_v2 | AlphaFold | D3ZHA9 | 1-829 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13695042 | ||||||||
Promoter ID: | EPDNEW_R5566 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Med16_1 | ||||||||
Description: | mediator complex subunit 16 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R5567 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
|
RGD ID: | 13695050 | ||||||||
Promoter ID: | EPDNEW_R5567 | ||||||||
Type: | single initiation site | ||||||||
Name: | Med16_2 | ||||||||
Description: | mediator complex subunit 16 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R5566 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
|
Database | Acc Id | Source(s) |
AGR Gene | RGD:1308001 | AgrOrtholog |
BioCyc Gene | G2FUF-34897 | BioCyc |
Ensembl Genes | ENSRNOG00000011315 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000015257 | ENTREZGENE |
ENSRNOT00000015257.7 | UniProtKB/TrEMBL | |
ENSRNOT00000080089.2 | UniProtKB/TrEMBL | |
ENSRNOT00000093264.2 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.130.10.10 | UniProtKB/TrEMBL |
InterPro | MED16_bridge | UniProtKB/TrEMBL |
Mediator_Med16 | UniProtKB/TrEMBL | |
Mediator_Med16 | UniProtKB/TrEMBL | |
Mediator_Med16_C | UniProtKB/TrEMBL | |
Quinoprot_gluc/sorb_DH | UniProtKB/TrEMBL | |
WD40/YVTN_repeat-like_dom | UniProtKB/TrEMBL | |
WD40_repeat | UniProtKB/TrEMBL | |
WD40_repeat_dom_sf | UniProtKB/TrEMBL | |
KEGG Report | rno:299607 | UniProtKB/TrEMBL |
NCBI Gene | 299607 | ENTREZGENE |
PANTHER | MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16 | UniProtKB/TrEMBL |
PTHR13224 | UniProtKB/TrEMBL | |
Pfam | Med16 | UniProtKB/TrEMBL |
Med16_bridge | UniProtKB/TrEMBL | |
Med16_C | UniProtKB/TrEMBL | |
WD40 | UniProtKB/TrEMBL | |
PhenoGen | Med16 | PhenoGen |
PROSITE | WD_REPEATS_2 | UniProtKB/TrEMBL |
WD_REPEATS_REGION | UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000011315 | RatGTEx |
SMART | WD40 | UniProtKB/TrEMBL |
Superfamily-SCOP | SSF50952 | UniProtKB/TrEMBL |
WD40_like | UniProtKB/TrEMBL | |
UniProt | A0A0G2K2K5 | ENTREZGENE, UniProtKB/TrEMBL |
A0A1W2Q603_RAT | UniProtKB/TrEMBL | |
A6K8V2 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZHA9 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2008-03-04 | Med16 | mediator complex subunit 16 | Thrap5_predicted | thyroid hormone receptor associated protein 5 (predicted) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-01-12 | Thrap5_predicted | thyroid hormone receptor associated protein 5 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |