Gene: Lrrk1 (leucine-rich repeat kinase 1) Rattus norvegicus
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Symbol: Lrrk1
Name: leucine-rich repeat kinase 1
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN bone resorption (ortholog); negative regulation of peptidyl-tyrosine phosphorylation (ortholog); osteoclast development (ortholog); ASSOCIATED WITH Schizophrenia (ortholog); schizophrenia (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,4-dinitrotoluene; all-trans-retinoic acid; C60 fullerene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: leucine-rich repeat serine/threonine-protein kinase 1; LOC308703
Orthologs:
Homo sapiens (human) : LRRK1 (leucine rich repeat kinase 1)  HGNC  AGR
Mus musculus (house mouse) : Lrrk1 (leucine-rich repeat kinase 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Lrrk1 (leucine rich repeat kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LRRK1 (leucine rich repeat kinase 1)
Canis lupus familiaris (dog) : LRRK1 (leucine rich repeat kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrrk1 (leucine rich repeat kinase 1)
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Allele / Splice: Lrrk1em1SageLrrk2em1Sage   Lrrk1em1Sage  
Genetic Models: LE-Lrrk1em1Sage-/-Lrrk2em1Sage-/- LE-Lrrk1em1SageLrrk2em1Sage LE-Lrrk1em1Sage-/- LE-Lrrk1em1Sage
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01127,166,866 - 127,301,053 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01128,248,473 - 128,372,456 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41120,695,657 - 120,836,324 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11120,773,221 - 120,921,758 (-)NCBI
Celera1112,054,004 - 112,179,350 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Lrrk1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308000
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE