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Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:1317472 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SELPLG mRNA | CTD | PMID:22079256 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1317473 | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SELPLG promoter] | CTD | PMID:19654925 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:1317473 | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SELPLG mRNA | CTD | PMID:20188158 | 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid | decreases expression | ISO | RGD:1317472 | 6480464 | Am 580 results in decreased expression of SELPLG mRNA | CTD | PMID:16982809 | all-trans-retinoic acid | multiple interactions | ISO | RGD:1317472 | 6480464 | [Tretinoin co-treated with arsenic trioxide] results in increased expression of SELPLG mRNA | CTD | PMID:15894607 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SELPLG mRNA | CTD | PMID:16483693 | atrazine | multiple interactions | ISO | RGD:1317472 | 6480464 | [Atrazine co-treated with Arsenates] results in increased expression of SELPLG mRNA | CTD | PMID:18585445 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:1317473 | 6480464 | Diethylhexyl Phthalate results in increased expression of SELPLG mRNA | CTD | PMID:19850644 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | RGD:1317473 | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of SELPLG mRNA] | CTD | PMID:19850644 | chloroprene | decreases expression | ISO | RGD:1317473 | 6480464 | Chloroprene results in decreased expression of SELPLG mRNA | CTD | PMID:23125180 | choline | multiple interactions | ISO | RGD:1317473 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SELPLG mRNA | CTD | PMID:20938992 | clofibrate | multiple interactions | ISO | RGD:1317473 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SELPLG mRNA; more ... | CTD | PMID:17585979 | diarsenic trioxide | multiple interactions | ISO | RGD:1317472 | 6480464 | [Tretinoin co-treated with arsenic trioxide] results in increased expression of SELPLG mRNA | CTD | PMID:15894607 | diethylstilbestrol | decreases expression | ISO | RGD:1317473 | 6480464 | Diethylstilbestrol results in decreased expression of SELPLG mRNA | CTD | PMID:21041162 | disodium selenite | increases expression | ISO | RGD:1317472 | 6480464 | Sodium Selenite results in increased expression of SELPLG mRNA | CTD | PMID:18175754 | folic acid | multiple interactions | ISO | RGD:1317473 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SELPLG mRNA | CTD | PMID:20938992 | genistein | decreases expression | ISO | RGD:1317473 | 6480464 | Genistein results in decreased expression of SELPLG mRNA | CTD | PMID:21048042 | hydralazine | multiple interactions | ISO | RGD:1317472 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in decreased expression of SELPLG mRNA | CTD | PMID:17183730 | hypochlorous acid | decreases expression | ISO | RGD:1317473 | 6480464 | Hypochlorous Acid results in decreased expression of SELPLG mRNA | CTD | PMID:19376150 | isotretinoin | increases expression | ISO | RGD:1317472 | 6480464 | Isotretinoin results in increased expression of SELPLG mRNA | CTD | PMID:20436886 | L-methionine | multiple interactions | ISO | RGD:1317473 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SELPLG mRNA | CTD | PMID:20938992 | mangiferin | decreases expression | ISO | RGD:1317473 | 6480464 | mangiferin results in decreased expression of SELPLG mRNA | CTD | PMID:15135318 | paracetamol | multiple interactions | ISO | RGD:1317473 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SELPLG mRNA; more ... | CTD | PMID:17585979 | paracetamol | affects expression | ISO | RGD:1317473 | 6480464 | Acetaminophen affects the expression of SELPLG mRNA | CTD | PMID:17562736 | phencyclidine | increases expression | ISO | RGD:1317473 | 6480464 | Phencyclidine results in increased expression of SELPLG mRNA | CTD | PMID:12105081 | rosiglitazone | decreases expression | ISO | RGD:1317472 | 6480464 | rosiglitazone results in decreased expression of SELPLG mRNA | CTD | PMID:16982809 | valproic acid | multiple interactions | ISO | RGD:1317472 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in decreased expression of SELPLG mRNA | CTD | PMID:17183730 | zinc dichloride | increases expression | ISO | RGD:1317472 | 6480464 | zinc chloride results in increased expression of SELPLG mRNA | CTD | PMID:21540303 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Cell adhesion molecules (CAMs) |
| Staphylococcus aureus infection | |
| Pathway Interaction Database | amb2 Integrin signaling (PID:200127) |
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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| External Database Links | |
| KEGG Pathway | Cell adhesion molecules (CAMs) |
| Staphylococcus aureus infection | |
| Pathway Interaction Database | amb2 Integrin signaling (PID:200127) |
References - curated
References - uncurated
RGD Disease Portals| Selplg has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Selplg (Rattus norvegicus) |
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| SELPLG (Homo sapiens) |
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| Selplg (Mus musculus) |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| RefSeq Acc Id: | NM_001013230 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001013248 | ||||||||||||||||||||
| Peptide Label: | precursor | ||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_001013248 | (Get FASTA) |
| GenBank Protein | AAM21052 | (Get FASTA) |
| CAO91829 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000000699 | UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000000888 | UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000000888 | UniProtKB/TrEMBL |
| Entrez Gene | 363930 | ENTREZGENE |
| HomoloGene Group ID | 2261 | ENTREZGENE |
| InterPro | PSGL-1 | UniProtKB/TrEMBL |
| KEGG Report | rno:363930 | ENTREZGENE, UniProtKB/TrEMBL |
| PANTHER | PTHR17384 | UniProtKB/TrEMBL |
| UniGene | Rn.215585 | ENTREZGENE |
| UniProt | F6T9E7_RAT | UniProtKB/TrEMBL |
| Q8K5B0_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2009-12-15 | Selplg | selectin P ligand | Selplg | selectin, platelet (p-selectin) ligand | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2008-03-07 | Selplg | selectin, platelet (p-selectin) ligand | Selpl_predicted | selectin, platelet (p-selectin) ligand (predicted) | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2005-01-12 | Selpl_predicted | selectin, platelet (p-selectin) ligand (predicted) | Symbol and Name status set to approved | 1724 | APPROVED |
| More on Selplg | |
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Entrez Gene |
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Ensembl Gene |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 1307971 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-05-28 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




