Grep1 (glycine rich extracellular protein 1) - Rat Genome Database

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Gene: Grep1 (glycine rich extracellular protein 1) Rattus norvegicus
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Symbol: Grep1
Name: glycine rich extracellular protein 1
RGD ID: 1307032
Description: ASSOCIATED WITH Experimental Neoplasms (ortholog); Neoplasm Invasiveness (ortholog); squamous cell carcinoma (ortholog); INTERACTS WITH aristolochic acid A (ortholog); bisphenol A (ortholog); fipronil (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: elastin; fibroin heavy chain; glycine-rich extracellular protein 1; Linc00514; LOC102553977; LOC360486; long intergenic non-protein coding RNA 514; RGD1307032; similar to RIKEN cDNA 1520401A03 gene; uncharacterized LOC102553977; uncharacterized protein LOC360486
RGD Orthologs
Human
Mouse
Bonobo
Dog
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,231,755 - 13,253,200 (-)NCBIGRCr8
mRatBN7.21012,727,164 - 12,748,629 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,727,166 - 12,741,819 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01013,041,074 - 13,053,416 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01012,859,783 - 12,860,596 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41012,961,325 - 12,973,665 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11012,961,324 - 12,976,103 (-)NCBI
Celera1012,422,538 - 12,435,893 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Grep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,231,755 - 13,253,200 (-)NCBIGRCr8
mRatBN7.21012,727,164 - 12,748,629 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,727,166 - 12,741,819 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01013,041,074 - 13,053,416 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01012,859,783 - 12,860,596 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41012,961,325 - 12,973,665 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11012,961,324 - 12,976,103 (-)NCBI
Celera1012,422,538 - 12,435,893 (-)NCBICelera
Cytogenetic Map10q12NCBI
GREP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,988,262 - 3,002,011 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,988,256 - 3,002,016 (+)EnsemblGRCh38hg38GRCh38
GRCh37163,038,263 - 3,052,012 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera163,244,505 - 3,249,960 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef163,010,969 - 3,016,424 (+)NCBIHuRef
CHM1_1163,039,036 - 3,044,491 (+)NCBICHM1_1
T2T-CHM13v2.0163,014,944 - 3,028,691 (+)NCBIT2T-CHM13v2.0
Grep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391723,923,582 - 23,945,299 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1723,923,462 - 23,941,757 (-)EnsemblGRCm39 Ensembl
GRCm381723,704,608 - 23,726,451 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,704,488 - 23,722,783 (-)EnsemblGRCm38mm10GRCm38
MGSCv371723,841,455 - 23,858,907 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,432,110 - 23,450,405 (-)NCBIMGSCv36mm8
MGSCv361722,893,786 - 22,911,851 (-)NCBIMGSCv36mm8
Cytogenetic Map17A3.3NCBI
cM Map1712.01NCBI
GREP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,533,003 - 3,547,865 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1167,311,389 - 7,326,251 (+)NCBINHGRI_mPanPan1
LOC106558903
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,183,097 - 38,194,899 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,423,639 - 39,435,307 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,493,706 - 38,505,384 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1638,179,488 - 38,191,152 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,151,996 - 38,163,637 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,627,767 - 38,639,448 (-)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Grep1
129 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000109126   ⟹   ENSRNOP00000088642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1012,727,166 - 12,741,819 (-)Ensembl
RefSeq Acc Id: XM_063270082   ⟹   XP_063126152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,231,755 - 13,253,200 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063126152 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03770 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000088642.1
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000088642   ⟸   ENSRNOT00000109126
RefSeq Acc Id: XP_063126152   ⟸   XM_063270082

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-25911 BioCyc
Ensembl Genes ENSRNOG00000065545 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000109126.1 UniProtKB/TrEMBL
NCBI Gene 360486 ENTREZGENE
PhenoGen Grep1 PhenoGen
RatGTEx ENSRNOG00000065545 RatGTEx
UniProt A0A8I6A9U7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Grep1  glycine rich extracellular protein 1  Linc00514  long intergenic non-protein coding RNA 514  Data merged from RGD:149736160 737654 PROVISIONAL
2022-02-04 Grep1  glycine rich extracellular protein 1  Linc00514  long intergenic non-protein coding RNA 514  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-08-09 Linc00514  long intergenic non-protein coding RNA 514      Symbol and Name status set to provisional 45752 PROVISIONAL
2021-03-09 Linc00514  long intergenic non-protein coding RNA 514  LOC102553977  uncharacterized LOC102553977  Data merged from RGD:7627866 737654 PROVISIONAL
2013-12-18 LOC102553977  uncharacterized LOC102553977      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-10-10 Linc00514  long intergenic non-protein coding RNA 514  RGD1307032  similar to RIKEN cDNA 1520401A03 gene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1307032  similar to RIKEN cDNA 1520401A03 gene   RGD1307032_predicted  similar to RIKEN cDNA 1520401A03 gene (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1307032_predicted  similar to RIKEN cDNA 1520401A03 gene (predicted)  LOC360486_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC360486_predicted  similar to RIKEN cDNA 1520401A03 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL