Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | Mdga1 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of MDGA1 mRNA | CTD | PMID:28960355 | 17beta-estradiol | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of MDGA1 mRNA | CTD | PMID:30165855 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Mdga1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Mdga1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MDGA1 mRNA | CTD | PMID:33387578 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MDGA1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | decreases expression | ISO | Mdga1 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of MDGA1 mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Mdga1 (Mus musculus) | 6480464 | bisphenol S affects the methylation of MDGA1 gene | CTD | PMID:31683443 | 4,4'-sulfonyldiphenol | increases methylation | ISO | Mdga1 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of MDGA1 exon | CTD | PMID:33297965 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of MDGA1 mRNA | CTD | PMID:25825206 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of MDGA1 mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of MDGA1 mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | ISO | MDGA1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of MDGA1 gene and Aflatoxin B1 results in decreased methylation of MDGA1 intron | CTD | PMID:27153756 and PMID:30157460 | Aflatoxin B2 alpha | decreases methylation | ISO | MDGA1 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of MDGA1 intron | CTD | PMID:30157460 | aristolochic acid A | increases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of MDGA1 mRNA | CTD | PMID:33212167 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of MDGA1 gene | CTD | PMID:35440735 | benzo[a]pyrene | affects methylation | ISO | MDGA1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MDGA1 intron | CTD | PMID:30157460 | benzo[a]pyrene | decreases methylation | ISO | MDGA1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of MDGA1 promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of MDGA1 mRNA | CTD | PMID:31163220 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MDGA1 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | decreases expression | ISO | Mdga1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of MDGA1 mRNA | CTD | PMID:32156529 | bisphenol A | increases expression | ISO | Mdga1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of MDGA1 mRNA | CTD | PMID:32370801 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MDGA1 mRNA | CTD | PMID:29097150 and PMID:34947998 | bisphenol A | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MDGA1 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MDGA1 mRNA | CTD | PMID:28628672 and PMID:31601247 | bisphenol F | decreases expression | ISO | Mdga1 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of MDGA1 mRNA | CTD | PMID:30951980 | butanal | decreases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of MDGA1 mRNA | CTD | PMID:26079696 | cantharidin | decreases expression | ISO | Mdga1 (Mus musculus) | 6480464 | Cantharidin results in decreased expression of MDGA1 mRNA | CTD | PMID:36907384 | carbon nanotube | increases expression | ISO | Mdga1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MDGA1 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Mdga1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of MDGA1 mRNA | CTD | PMID:37019170 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of MDGA1 mRNA | CTD | PMID:27523638 | dexamethasone | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MDGA1 mRNA | CTD | PMID:28628672 | dorsomorphin | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MDGA1 mRNA | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of MDGA1 mRNA | CTD | PMID:30031762 | epoxiconazole | affects expression | ISO | Mdga1 (Mus musculus) | 6480464 | epoxiconazole affects the expression of MDGA1 mRNA | CTD | PMID:35436446 | ethanol | affects expression | ISO | Mdga1 (Mus musculus) | 6480464 | Ethanol affects the expression of MDGA1 mRNA | CTD | PMID:30319688 | ethanol | increases expression | ISO | Mdga1 (Mus musculus) | 6480464 | Ethanol results in increased expression of MDGA1 mRNA | CTD | PMID:30319688 | fulvestrant | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of MDGA1 gene | CTD | PMID:31601247 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of MDGA1 mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MDGA1 mRNA | CTD | PMID:28628672 | isoprenaline | decreases expression | ISO | Mdga1 (Mus musculus) | 6480464 | Isoproterenol results in decreased expression of MDGA1 mRNA | CTD | PMID:20003209 | Licochalcone B | increases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | licochalcone B results in increased expression of MDGA1 mRNA | CTD | PMID:33647349 | maneb | multiple interactions | ISO | Mdga1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of MDGA1 mRNA | CTD | PMID:36117858 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of MDGA1 gene | CTD | PMID:35440735 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Mdga1 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of MDGA1 mRNA | CTD | PMID:22401849 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of MDGA1 mRNA | CTD | PMID:36695872 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of MDGA1 gene | CTD | PMID:33148267 | paracetamol | affects expression | ISO | Mdga1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MDGA1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of MDGA1 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MDGA1 mRNA | CTD | PMID:29067470 | paracetamol | decreases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of MDGA1 mRNA | CTD | PMID:26690555 | paraquat | multiple interactions | ISO | Mdga1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of MDGA1 mRNA | CTD | PMID:36117858 | PCB138 | multiple interactions | ISO | Mdga1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of MDGA1 gene | CTD | PMID:33148267 | SB 431542 | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MDGA1 mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of MDGA1 mRNA | CTD | PMID:25895662 | sodium arsenite | increases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of MDGA1 mRNA | CTD | PMID:34032870 | sodium arsenite | decreases expression | ISO | Mdga1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of MDGA1 mRNA | CTD | PMID:37682722 | sotorasib | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MDGA1 mRNA | CTD | PMID:36139627 | sunitinib | decreases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of MDGA1 mRNA | CTD | PMID:31533062 | trametinib | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of MDGA1 mRNA | CTD | PMID:36139627 | triptonide | increases expression | ISO | Mdga1 (Mus musculus) | 6480464 | triptonide results in increased expression of MDGA1 mRNA | CTD | PMID:33045310 | valproic acid | increases expression | ISO | MDGA1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MDGA1 mRNA | CTD | PMID:26272509 | valproic acid | multiple interactions | ISO | MDGA1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MDGA1 mRNA | CTD | PMID:27188386 | |