Agpat5 (1-acylglycerol-3-phosphate O-acyltransferase 5)

Gene: Agpat5 (1-acylglycerol-3-phosphate O-acyltransferase 5) Rattus norvegicus

Analyze

Symbol:

Agpat5

Name:

1-acylglycerol-3-phosphate O-acyltransferase 5

RGD ID:

1306405

Description:

Predicted to enable 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Predicted to act upstream of or within acylglycerol metabolic process and hematopoietic progenitor cell differentiation. Predicted to be located in endoplasmic reticulum membrane; nuclear envelope; and nucleolus. Predicted to be active in endoplasmic reticulum and mitochondrion. Orthologous to human AGPAT5 (1-acylglycerol-3-phosphate O-acyltransferase 5); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon; 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon); LOC306582; MGC188222; RGD1306405; similar to 1-acylglycerolphosphate acyltransferase-epsilon

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	77,641,887 - 77,688,148 (-)	NCBI		GRCr8
mRatBN7.2	16	70,939,480 - 70,985,745 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	70,943,135 - 70,985,560 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	76,216,342 - 76,262,602 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	79,662,971 - 79,709,372 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	74,912,389 - 74,958,791 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	75,812,837 - 75,855,996 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	75,812,997 - 75,855,745 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	75,417,447 - 75,460,608 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	75,745,813 - 75,788,182 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	75,747,341 - 75,789,023 (-)	NCBI
Celera	16	68,789,188 - 68,831,515 (-)	NCBI		Celera
Cytogenetic Map	16	q12.5	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Keloid (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (EXP,ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

all-trans-retinoic acid (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

diarsenic trioxide (ISO)

dicrotophos (ISO)

dioxygen (ISO)

ethanol (ISO)

formaldehyde (ISO)

gentamycin (EXP)

hexadecanoic acid (ISO)

ivermectin (ISO)

lead(0) (ISO)

leflunomide (ISO)

methimazole (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylparaben (ISO)

mitoxantrone (ISO)

nickel atom (ISO)

obeticholic acid (ISO)

oleic acid (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

propiconazole (ISO)

rotenone (EXP)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tetrachloromethane (ISO)

thioacetamide (EXP)

Triptolide (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acylglycerol metabolic process (ISO)

hematopoietic progenitor cell differentiation (ISO)

phosphatidylinositol acyl-chain remodeling (IBA)

Cellular Component

endomembrane system (IBA)

endoplasmic reticulum (IBA)

endoplasmic reticulum membrane (ISO)

mitochondrion (IBA,ISO)

nuclear envelope (ISO)

nucleolus (ISO)

Molecular Function

1-acylglycerol-3-phosphate O-acyltransferase activity (ISO)

acyltransferase activity (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15367102	PMID:15632090	PMID:16150824	PMID:18614015	PMID:21173190	PMID:24029230

Genomics

Comparative Map Data

Agpat5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	77,641,887 - 77,688,148 (-)	NCBI		GRCr8
mRatBN7.2	16	70,939,480 - 70,985,745 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	70,943,135 - 70,985,560 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	76,216,342 - 76,262,602 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	79,662,971 - 79,709,372 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	74,912,389 - 74,958,791 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	75,812,837 - 75,855,996 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	75,812,997 - 75,855,745 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	75,417,447 - 75,460,608 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	75,745,813 - 75,788,182 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	75,747,341 - 75,789,023 (-)	NCBI
Celera	16	68,789,188 - 68,831,515 (-)	NCBI		Celera
Cytogenetic Map	16	q12.5	NCBI

AGPAT5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	6,708,642 - 6,761,503 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	6,708,642 - 6,761,503 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	6,566,163 - 6,619,024 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	6,553,286 - 6,606,432 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	6,553,621 - 6,604,592	NCBI
Celera	8	6,543,403 - 6,596,547 (+)	NCBI		Celera
Cytogenetic Map	8	p23.1	NCBI
HuRef	8	6,346,776 - 6,399,929 (+)	NCBI		HuRef
CHM1_1	8	6,655,163 - 6,708,308 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	6,464,039 - 6,516,588 (+)	NCBI		T2T-CHM13v2.0

Agpat5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	18,896,295 - 18,934,429 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	18,896,293 - 18,941,377 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	18,846,279 - 18,884,413 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	18,846,277 - 18,891,361 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	18,846,279 - 18,884,413 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	18,846,481 - 18,884,358 (+)	NCBI		MGSCv36	mm8
Celera	8	18,979,696 - 19,017,832 (+)	NCBI		Celera
Cytogenetic Map	8	A1.3	NCBI
cM Map	8	10.3	NCBI

Agpat5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	54,007,228 - 54,036,277 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	54,005,001 - 54,052,363 (-)	NCBI	ChiLan1.0	ChiLan1.0

AGPAT5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	21,513,171 - 21,564,094 (+)	NCBI		NHGRI_mPanPan1-v2
Mhudiblu_PPA_v0	8	519,824 - 572,617 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	6,713,082 - 6,765,472 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	6,713,082 - 6,765,472 (+)	Ensembl	panpan1.1		panPan2

AGPAT5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	58,755,720 - 58,797,916 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	58,755,735 - 58,795,704 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	54,264,604 - 54,322,426 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	57,251,483 - 57,309,264 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	57,252,797 - 57,309,550 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	58,900,534 - 58,958,279 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	55,259,838 - 55,317,636 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	55,634,994 - 55,692,847 (-)	NCBI		UU_Cfam_GSD_1.0

Agpat5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	4,652,141 - 4,691,496 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936615	4,652,299 - 4,691,607 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936615	4,652,141 - 4,691,496 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AGPAT5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	37,801,183 - 37,853,468 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	37,801,121 - 37,853,472 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	43,013,522 - 43,065,868 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AGPAT5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	6,488,736 - 6,541,021 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	6,488,687 - 6,542,995 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	48,603,190 - 48,655,153 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Agpat5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624861	4,596,251 - 4,648,183 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624861	4,596,326 - 4,645,708 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Agpat5
224 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	118
Count of miRNA genes:	102
Interacting mature miRNAs:	109
Transcripts:	ENSRNOT00000031291
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	19004435	75226532	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	35288870	80288870	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	37752156	82752156	Rat
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	37752156	82752156	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	42396345	84729064	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	52726464	84729064	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	52726464	84729064	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	52726464	84729064	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	55711087	83402471	Rat
1298527	Arunc2	Aerobic running capacity QTL 2	2.9		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	68532716	75029966	Rat

Markers in Region

D16Rat37

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	70,968,519 - 70,968,745 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	75,838,775 - 75,839,000	NCBI	Rnor6.0
Rnor_5.0	16	75,443,387 - 75,443,612	UniSTS	Rnor5.0
RGSC_v3.4	16	75,771,209 - 75,771,434	UniSTS	RGSC3.4
RGSC_v3.4	16	75,771,208 - 75,771,434	RGD	RGSC3.4
RGSC_v3.1	16	75,771,473 - 75,771,699	RGD
Celera	16	68,814,554 - 68,814,771	UniSTS
RH 3.4 Map	16	698.7	RGD
RH 3.4 Map	16	698.7	UniSTS
RH 2.0 Map	16	803.7	RGD
SHRSP x BN Map	16	38.5199	RGD
FHH x ACI Map	16	40.2098	RGD
Cytogenetic Map	16	q12.5	UniSTS

RH136959

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	70,943,222 - 70,943,374 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	75,813,089 - 75,813,240	NCBI	Rnor6.0
Rnor_5.0	16	75,417,701 - 75,417,852	UniSTS	Rnor5.0
RGSC_v3.4	16	75,745,909 - 75,746,060	UniSTS	RGSC3.4
Celera	16	68,789,284 - 68,789,435	UniSTS
RH 3.4 Map	16	697.0	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

RH140593

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	70,955,225 - 70,955,424 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	75,825,484 - 75,825,682	NCBI	Rnor6.0
Rnor_6.0	16	75,714,713 - 75,714,911	NCBI	Rnor6.0
Rnor_5.0	16	75,430,096 - 75,430,294	UniSTS	Rnor5.0
Rnor_5.0	16	75,317,648 - 75,317,846	UniSTS	Rnor5.0
RGSC_v3.4	16	75,757,914 - 75,758,112	UniSTS	RGSC3.4
Celera	16	68,801,285 - 68,801,483	UniSTS
RH 3.4 Map	16	704.1	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

RH142766

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	70,943,846 - 70,944,019 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	75,813,713 - 75,813,885	NCBI	Rnor6.0
Rnor_5.0	16	75,418,325 - 75,418,497	UniSTS	Rnor5.0
RGSC_v3.4	16	75,746,533 - 75,746,705	UniSTS	RGSC3.4
Celera	16	68,789,908 - 68,790,080	UniSTS
RH 3.4 Map	16	698.8	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

BF387021

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	70,944,111 - 70,944,297 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	75,813,978 - 75,814,163	NCBI	Rnor6.0
Rnor_5.0	16	75,418,590 - 75,418,775	UniSTS	Rnor5.0
RGSC_v3.4	16	75,746,798 - 75,746,983	UniSTS	RGSC3.4
Celera	16	68,790,173 - 68,790,358	UniSTS
RH 3.4 Map	16	690.2	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

BE121319

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	70,986,539 - 70,986,695 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	75,856,795 - 75,856,950	NCBI	Rnor6.0
Rnor_5.0	16	75,461,407 - 75,461,562	UniSTS	Rnor5.0
RGSC_v3.4	16	75,789,232 - 75,789,387	UniSTS	RGSC3.4
Celera	16	68,832,565 - 68,832,720	UniSTS
RH 3.4 Map	16	691.9	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	41	35	21	19	21	7	10	74	33	34	11	7
Low		2	22	20		20	1	1		2	7		1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001134744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000031291 ⟹ ENSRNOP00000037069

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	70,943,135 - 70,985,560 (-)	Ensembl
Rnor_6.0 Ensembl	16	75,812,997 - 75,855,745 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000095454 ⟹ ENSRNOP00000080004

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	70,943,135 - 70,985,560 (-)	Ensembl

RefSeq Acc Id:

NM_001134744 ⟹ NP_001128216

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	77,641,887 - 77,688,148 (-)	NCBI
mRatBN7.2	16	70,939,480 - 70,985,745 (-)	NCBI
Rnor_6.0	16	75,812,993 - 75,855,745 (-)	NCBI
Rnor_5.0	16	75,417,447 - 75,460,608 (-)	NCBI
RGSC_v3.4	16	75,745,813 - 75,788,182 (-)	RGD
Celera	16	68,789,188 - 68,831,515 (-)	RGD

Sequence:

show sequence

CGAGCTGAGAGGATGCTGCTGTCCCTGGTGCTCCACACGTACTCTATGCGCTACCTGCTCCCGA
GCGTCCTGTTGCTGGGCTCGGCGCCCACCTACATGCTGGCCTGGACGCTGTGGCGGGTGCTGTC
CGCGCTGCTGCCCGCCCGTCTGTACCAGCGCGTGGACGACCGGCTTTACTGCGTCTACCAGAAC
ATGGTGCTCTTCTTCTTCGAGAACTACACCGGGGTCCAGATATTGCTATATGGAGATTTGCCAA
AAAATAAGGAAAATGTAATATATTTAGCAAATCATCAAAGCACAGACATGCTGGCTGCCCGACA
GGATGCTCTTGGACATGTGCGCTATGTCCTGAAAGACGGGTTAAAGTGGCTTCCATTGTATGGG
TTCTACTTTGCTCAGCACGGAGGAATTTATGTAAAACGAAGTGCCAAATTTAATGATAAAGAAA
TGAGAAGCAAGCTTCAGAGCTACGTGAACGCAGGAACACCAATGTATCTTGTGATTTTCCCAGA
GGGAACAAGGTATAATGCAACATATACAAAACTCCTCTCAGCCAGCCAGGCATTTGCTGCTCAG
CGGGGCCTTGCAGTATTAAAACACGTGCTGACACCAAGAATAAAGGCAACTCATGTTGCTTTTG
ATTCTATGAAGAGTCATTTAGATGCAATTTATGATGTCACAGTGGTTTACGAAGGGAATGAGAA
AAATTCAGGAAAATATTCAAATCCACCATCCATGACTGAGTTTCTCTGCAAACAGTGCCCAAGA
CTTCATATTCACTTTGACCGCATAGACAGAAAAGAAGTTCCAGAGGAACAAGAACACATGAAAA
AGTGGCTTCATGAGCGCTTTGAGATAAAAGATAAGTTGCTCGTAGAATTCTATGATTCACCAGA
TCCAGAAAGAAGGAACAAATTTCCCGGGAAACGCGTTCACTCCAGACTGAGTGTCAACAAGACT
TTACCGTCAGTGTTGATCCTGGGGAGCTTGACTGCGGCCATGCTCATGACGGAGTCTGGAAGGA
AACTGTACATGGGCACCTGGTTGTATGGAACCCTCCTTGGCTGCCTGTGGTTTGTCATTAAAGC
CTAAGCACGTGGAGGCTGCAGTCACCGTCTCTTACCGATGGCCGCACATTGCATCACACTGTTT
CCTGAGTTAGATACGGATGACTGAACACTGGATGAAGTGGCTGACCACAGCCGACATGCATCTG
ACGGGGCAGCACATGGCTTTTCAGCTGCCGGGCTTGCTGGACACATGGGAGCCGAGTGGAGCTT
ATGCTGGGGCTCTTCTTTTTTTTTTTTTTTTTTTTGGTATGTTTTCATGAATCAGTGTCTACGT
GTAAAGATGATCGGATGCTGCCTGTGATTTTGATGGCTGTATTTTAACATTAGTTTGCAGTGTG
TTTCGCTATATTGGTTATCTTCCATTTGACTACTTGGCAGCTCAGACTCTTAATACTAAAGTAT
TTTATATTTTCAAGCTATGTGATACTGGGTTTTTTGTTAATATCTGAAAGTCAATGAAAGACAC
TGTAACAATGCGCTAAGATGTTCCAAGAAAAAGGTGAGACGTATTCATAGCGGAAAAGATCTGT
CTAGTGTATATTTTTATTATATTGCTCTATTTAGCTAATTTTCTTTATATTTGCAAAATAATGA
ACACTTCTAATATTTATTAAAATGTTTAATTTGCATACCCCCTATTCTGCAGAGGATAACGTGT
CAAGTGTCAGAATAGACTGGCAGCTCAGCTCTGTCTCCTTTGGCAGAGCATTTAGTAGCCCAGC
CTCCGAGCGATTCTGTTAGTGCCTCCCAGTACCTGTGCCATTAAGTACTTATAAATGTAAGGGG
CTGTTACCTTCATGTCAGATGGACGCCCACGGAGCTGTAAGGTGAGAGAAGCCTGCCAGCATCC
TGTCTGTCCTAGCACGTGCCTTCTGCCCGGCTCCCTTTGCTTTTGGCACTGCGTTTGGTCTGGA
GTGTGGACGCCCATGGTTGTTCGCTGTCTGTTCCAGCCCTGACTCTCAGGCTTGGGGTCCTCCA
GTGGTGCTGTTCATTGTTGGGATGCGGGCAGTGCTGCTGGGCCGGGGGTGAGCCTCCTTGGCTA
CTGCAGAAGTATTGTACATTTGTTTATGGCAAGAACCATCAGGATTGGATAAATTTGTTATTTC
TCTTTGATTTCCATGGAGCCACACTATTGGTCCATGTCCCCTGTGAACAGAGCTACCTTCCAGG
ACCAAATCACACTCTAAAGTGTGATTTGCAATATTTCTATGTTGTAATTTAAGCGTAATTGCCT
ACTAGTCATTGAAGGTAACATTTCTGCAAACTTCATACAGATTTTTGTCACAAAATTACTATAC
CAATGATCTAGTTAAAATAGACCAATTGAATCATAATAAATAATTTTTTTTTAAATTGAGGGAA
AAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001399425 ⟹ NP_001386354

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	77,641,887 - 77,688,148 (-)	NCBI
mRatBN7.2	16	70,939,480 - 70,985,745 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001128216	(Get FASTA)	NCBI Sequence Viewer
	NP_001386354	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68222	(Get FASTA)	NCBI Sequence Viewer
	EDM08959	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000037069
	ENSRNOP00000037069.6
	ENSRNOP00000080004.1

RefSeq Acc Id:	NP_001128216 ⟸ NM_001134744
- Peptide Label:	isoform 1
- UniProtKB:	A0A8J8YCS6 (UniProtKB/TrEMBL), A0A8I5ZPQ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLSLVLHTYSMRYLLPSVLLLGSAPTYMLAWTLWRVLSALLPARLYQRVDDRLYCVYQNMVLF FFENYTGVQILLYGDLPKNKENVIYLANHQSTDMLAARQDALGHVRYVLKDGLKWLPLYGFYFA QHGGIYVKRSAKFNDKEMRSKLQSYVNAGTPMYLVIFPEGTRYNATYTKLLSASQAFAAQRGLA VLKHVLTPRIKATHVAFDSMKSHLDAIYDVTVVYEGNEKNSGKYSNPPSMTEFLCKQCPRLHIH FDRIDRKEVPEEQEHMKKWLHERFEIKDKLLVEFYDSPDPERRNKFPGKRVHSRLSVNKTLPSV LILGSLTAAMLMTESGRKLYMGTWLYGTLLGCLWFVIKA hide sequence

RefSeq Acc Id:

ENSRNOP00000037069 ⟸ ENSRNOT00000031291

RefSeq Acc Id:

ENSRNOP00000080004 ⟸ ENSRNOT00000095454

RefSeq Acc Id:	NP_001386354 ⟸ NM_001399425
- Peptide Label:	isoform 2
- UniProtKB:	B4F7C8 (UniProtKB/TrEMBL), A6IWB3 (UniProtKB/TrEMBL), G3V965 (UniProtKB/TrEMBL), A0A8I5ZPQ7 (UniProtKB/TrEMBL)

Protein Domains

Phospholipid/glycerol acyltransferase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V965-F1-model_v2	AlphaFold	G3V965	1-359	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700215

Promoter ID:

EPDNEW_R10739

Type:

initiation region

Name:

Agpat5_1

Description:

1-acylglycerol-3-phosphate O-acyltransferase 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	75,855,759 - 75,855,819	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306405	AgrOrtholog
BioCyc Gene	G2FUF-10807	BioCyc
BioCyc Pathway	PWY-5667 [CDP-diacylglycerol biosynthesis I]	BioCyc
	PWY-7411 [phosphatidate biosynthesis (yeast)]	BioCyc
	PWY-7417 [phospholipid remodeling (phosphatidate, yeast)]	BioCyc
	PWY-7782 [plasmalogen biosynthesis]	BioCyc
	PWY-8053 [anandamide biosynthesis II]	BioCyc
	TRIGLSYN-PWY [diacylglycerol and triacylglycerol biosynthesis]	BioCyc
BioCyc Pathway Image	PWY-5667	BioCyc
	PWY-7411	BioCyc
	PWY-7417	BioCyc
	PWY-7782	BioCyc
	PWY-8053	BioCyc
	TRIGLSYN-PWY	BioCyc
Ensembl Genes	ENSRNOG00000028623	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000031291	ENTREZGENE
	ENSRNOT00000031291.6	UniProtKB/TrEMBL
	ENSRNOT00000095454.1	UniProtKB/TrEMBL
InterPro	Acyltransf_C	UniProtKB/TrEMBL
	Acyltransferase	UniProtKB/TrEMBL
KEGG Report	rno:306582	UniProtKB/TrEMBL
NCBI Gene	306582	ENTREZGENE
PANTHER	1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON	UniProtKB/TrEMBL
	1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED	UniProtKB/TrEMBL
Pfam	Acyltransf_C	UniProtKB/TrEMBL
	Acyltransferase	UniProtKB/TrEMBL
PhenoGen	Agpat5	PhenoGen
RatGTEx	ENSRNOG00000028623	RatGTEx
SMART	PlsC	UniProtKB/TrEMBL
Superfamily-SCOP	Glycerol-3-phosphate (1)-acyltransferase	UniProtKB/TrEMBL
UniProt	A0A8I5ZPQ7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8J8YCS6	ENTREZGENE, UniProtKB/TrEMBL
	A6IWB3	ENTREZGENE, UniProtKB/TrEMBL
	B4F7C8	ENTREZGENE
	G3V965	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	B4F7C8	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-02-21	Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5	Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)	Agpat5_predicted	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Agpat5_predicted	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) (predicted)	RGD1306405_predicted	similar to 1-acylglycerolphosphate acyltransferase-epsilon (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1306405_predicted	similar to 1-acylglycerolphosphate acyltransferase-epsilon (predicted)	LOC306582_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC306582_predicted	similar to 1-acylglycerolphosphate acyltransferase-epsilon (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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