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Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | benzo[a]pyrene | decreases expression | ISO | RGD:1314876 | 6480464 | Benzo(a)pyrene results in decreased expression of TFAP2B mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | RGD:1314876 | 6480464 | Benzo(a)pyrene results in increased expression of TFAP2B mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | RGD:1314875 | 6480464 | Benzo(a)pyrene results in increased expression of TFAP2B mRNA | CTD | PMID:22316170 | carbamazepine | multiple interactions | EXP | | 6480464 | Carbamazepine inhibits the reaction [TFAP2B protein binds to PLA2G4A gene] | CTD | PMID:16806101 | carbamazepine | decreases activity | EXP | | 6480464 | Carbamazepine results in decreased activity of TFAP2B protein | CTD | PMID:16806101 | carbonyl sulfide | affects expression | EXP | | 6480464 | carbonyl sulfide affects the expression of TFAP2B mRNA | CTD | PMID:19395590 | hydrogen peroxide | affects expression | ISO | RGD:1314875 | 6480464 | Hydrogen Peroxide affects the expression of TFAP2B mRNA | CTD | PMID:21179406 | manganese atom | increases expression | ISO | RGD:1314875 | 6480464 | Manganese results in increased expression of TFAP2B mRNA | CTD | PMID:17175027 | manganese(0) | increases expression | ISO | RGD:1314875 | 6480464 | Manganese results in increased expression of TFAP2B mRNA | CTD | PMID:17175027 | manganese(II) chloride | increases expression | ISO | RGD:1314875 | 6480464 | manganese chloride results in increased expression of TFAP2B mRNA | CTD | PMID:17175027 | nickel atom | affects expression | ISO | RGD:1314875 | 6480464 | Nickel affects the expression of TFAP2B mRNA | CTD | PMID:14575637 | nickel atom | multiple interactions | ISO | RGD:1314875 | 6480464 | trichostatin A inhibits the reaction [Nickel affects the expression of TFAP2B mRNA] | CTD | PMID:14575637 | trichostatin A | multiple interactions | ISO | RGD:1314875 | 6480464 | trichostatin A inhibits the reaction [Nickel affects the expression of TFAP2B mRNA] | CTD | PMID:14575637 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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References - curated| 1. |
Berggard C, etal., BMC Pharmacol. 2005 Jan 21;5(1):1. |
| 2. |
Damberg M, etal., Life Sci. 2000 Dec 29;68(6):669-78. |
| 3. |
GOA data from the GO Consortium |
| 4. |
Hong SJ, etal., Mol Cell Neurosci. 2011 Jan;46(1):245-51. Epub 2010 Sep 27. |
| 5. |
MGD data from the GO Consortium |
| 6. |
Mishra SK, etal., J Biol Chem. 2005 May 13;280(19):19270-80. Epub 2005 Feb 22. |
| 7. |
Rao JS, etal., Neuropsychopharmacology. 2005 Nov;30(11):2006-13. |
| 8. |
RGD automated data pipeline |
| 9. |
RGD automated import pipeline for gene-chemical interactions |
| 10. |
RGD Automated Pipelines |
| 11. |
RGD comprehensive gene curation |
| 12. |
Satoda M, etal., Nat Genet. 2000 May;25(1):42-6. |
| 13. |
Tao Y, etal., Endocrinology. 2006 Apr;147(4):1685-96. Epub 2005 Dec 22. |
References - uncurated| PubMed | 20448150 |
RGD Disease Portals| Tfap2b has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Tfap2b (Rattus norvegicus) |
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| TFAP2B (Homo sapiens) |
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| Tfap2b (Mus musculus) |
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Position Markers| Tcfap2b |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_001106896 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR06059143 | (Get FASTA) | Search GEO for Microarray Profiles |
| AABR06059144 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058594 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058595 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058596 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01058597 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH473987 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_001106896 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_001100366 | ||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_001100366 | (Get FASTA) |
| GenBank Protein | EDM18662 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000011823 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000030726 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000030912 | ENTREZGENE, UniProtKB/TrEMBL |
| Entrez Gene | 301285 | ENTREZGENE |
| HomoloGene Group ID | 20688 | ENTREZGENE |
| InterPro | TF_AP2 | UniProtKB/TrEMBL |
| TF_AP2_beta | UniProtKB/TrEMBL | |
| TF_AP2_C | UniProtKB/TrEMBL | |
| KEGG Report | rno:301285 | ENTREZGENE, UniProtKB/TrEMBL |
| PANTHER | TF_AP2 | UniProtKB/TrEMBL |
| Pfam | TF_AP-2 | UniProtKB/TrEMBL |
| PRINTS | AP2BTNSCPFCT | UniProtKB/TrEMBL |
| AP2TNSCPFCT | UniProtKB/TrEMBL | |
| UniGene | Rn.12263 | ENTREZGENE |
| UniProt | D4A505_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2011-06-09 | Tfap2b | transcription factor AP-2 beta | Tcfap2b | transcription factor AP-2 beta | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2008-04-30 | Tcfap2b | transcription factor AP-2 beta | Tcfap2b_predicted | transcription factor AP-2 beta (predicted) | 'predicted' is removed | 24709 | APPROVED |
| 2005-01-12 | Tcfap2b_predicted | transcription factor AP-2 beta (predicted) | Symbol and Name status set to approved | 1724 | APPROVED |
| More on Tfap2b | |
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Entrez Gene |
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Ensembl Gene |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 1306321 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-05-28 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




