Nav3 (neuron navigator 3) - Rat Genome Database

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Gene: Nav3 (neuron navigator 3) Rattus norvegicus
Analyze
Symbol: Nav3
Name: neuron navigator 3
RGD ID: 1306259
Description: Predicted to enable microtubule binding activity. Predicted to be involved in negative regulation of cell migration; negative regulation of interleukin-2 production; and regulation of microtubule polymerization or depolymerization. Predicted to be located in nuclear envelope. Predicted to colocalize with microtubule end. Human ortholog(s) of this gene implicated in opiate dependence. Orthologous to human NAV3 (neuron navigator 3); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC314814; pore membrane and/or filament interacting like protein 1; RGD1306259; similar to neuron navigator 3; steerin 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8746,938,577 - 47,726,839 (-)NCBIGRCr8
mRatBN7.2745,052,206 - 45,840,471 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl745,054,296 - 45,840,698 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx746,971,991 - 47,300,504 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0749,175,089 - 49,503,591 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0748,952,850 - 49,281,357 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0752,164,805 - 52,508,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl752,165,233 - 52,404,774 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0752,174,059 - 52,510,816 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4748,505,502 - 48,862,109 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1748,681,551 - 48,882,272 (-)NCBI
Celera741,897,661 - 42,222,850 (-)NCBICelera
Cytogenetic Map7q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
genistein  (ISO)
ketamine  (EXP)
lipopolysaccharide  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methapyrilene  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
nickel sulfate  (ISO)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
PD 0325901  (ISO)
pentanal  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
trametinib  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Substance dependence low-density whole genome association study in two distinct American populations. Yu Y, etal., Hum Genet. 2008 Jun;123(5):495-506. doi: 10.1007/s00439-008-0501-0. Epub 2008 Apr 26.
Additional References at PubMed
PMID:12062803   PMID:16166283   PMID:25678558  


Genomics

Comparative Map Data
Nav3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8746,938,577 - 47,726,839 (-)NCBIGRCr8
mRatBN7.2745,052,206 - 45,840,471 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl745,054,296 - 45,840,698 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx746,971,991 - 47,300,504 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0749,175,089 - 49,503,591 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0748,952,850 - 49,281,357 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0752,164,805 - 52,508,145 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl752,165,233 - 52,404,774 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0752,174,059 - 52,510,816 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4748,505,502 - 48,862,109 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1748,681,551 - 48,882,272 (-)NCBI
Celera741,897,661 - 42,222,850 (-)NCBICelera
Cytogenetic Map7q21NCBI
NAV3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381277,571,862 - 78,213,010 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1277,324,641 - 78,213,010 (+)EnsemblGRCh38hg38GRCh38
GRCh371278,224,674 - 78,606,790 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361276,749,200 - 77,130,921 (+)NCBINCBI36Build 36hg18NCBI36
Build 341276,727,664 - 77,108,408NCBI
Celera1277,890,812 - 78,272,363 (+)NCBICelera
Cytogenetic Map12q21.2NCBI
HuRef1275,278,625 - 75,660,456 (+)NCBIHuRef
CHM1_11278,191,333 - 78,573,061 (+)NCBICHM1_1
T2T-CHM13v2.01277,549,793 - 78,191,344 (+)NCBIT2T-CHM13v2.0
Nav3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910109,517,121 - 110,292,148 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10109,517,120 - 110,292,065 (-)EnsemblGRCm39 Ensembl
GRCm3810109,681,260 - 110,455,722 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10109,681,259 - 110,456,204 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710109,120,495 - 109,437,275 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610109,120,495 - 109,437,275 (-)NCBIMGSCv36mm8
Celera10111,625,829 - 111,937,317 (-)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1057.18NCBI
Nav3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540516,869,441 - 17,213,325 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540516,428,643 - 17,213,253 (+)NCBIChiLan1.0ChiLan1.0
NAV3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21085,351,778 - 86,244,699 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11285,348,180 - 86,241,091 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01274,835,566 - 75,724,859 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11277,934,165 - 78,576,240 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1278,192,076 - 78,573,746 (+)Ensemblpanpan1.1panPan2
NAV3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11519,931,037 - 20,937,244 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1520,581,709 - 20,935,007 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1520,600,910 - 21,419,035 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01520,456,514 - 21,275,505 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1520,919,569 - 21,274,597 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11520,518,315 - 20,874,199 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01520,113,721 - 20,933,335 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01520,983,885 - 21,173,307 (+)NCBIUU_Cfam_GSD_1.0
Nav3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494539,453,343 - 40,242,390 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365685,920,421 - 6,275,133 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365685,694,326 - 6,275,112 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAV3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5103,013,806 - 103,368,021 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15103,013,798 - 103,863,222 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25108,177,031 - 108,232,183 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NAV3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11172,891,767 - 73,780,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037171,659,909 - 172,574,616 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nav3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475019,964,847 - 20,313,424 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475019,963,321 - 20,792,249 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nav3
5375 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat

Markers in Region
D7Got33  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2745,308,441 - 45,308,655 (+)MAPPERmRatBN7.2
Rnor_6.0752,424,836 - 52,425,049NCBIRnor6.0
Rnor_5.0752,428,441 - 52,428,654UniSTSRnor5.0
RGSC_v3.4748,762,267 - 48,762,481RGDRGSC3.4
RGSC_v3.4748,762,268 - 48,762,481UniSTSRGSC3.4
RGSC_v3.1748,782,539 - 48,782,752RGD
Celera742,151,372 - 42,151,585UniSTS
RH 3.4 Map7380.91UniSTS
RH 3.4 Map7380.91RGD
RH 2.0 Map7353.6RGD
Cytogenetic Map7q21UniSTS
D12S1376E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2745,139,455 - 45,139,546 (+)MAPPERmRatBN7.2
Rnor_6.0752,258,643 - 52,258,733NCBIRnor6.0
Rnor_5.0752,262,833 - 52,262,923UniSTSRnor5.0
RGSC_v3.4748,591,401 - 48,591,491UniSTSRGSC3.4
Celera741,982,145 - 41,982,235UniSTS
Cytogenetic Map7q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 4 8 62 22
Low 1 41 38 26 11 26 8 10 12 13 40 11 8
Below cutoff 2 15 15 15 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000082100   ⟹   ENSRNOP00000070987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl745,054,296 - 45,392,259 (-)Ensembl
Rnor_6.0 Ensembl752,165,233 - 52,404,774 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097268   ⟹   ENSRNOP00000079901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl745,054,296 - 45,840,698 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108591   ⟹   ENSRNOP00000078833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl745,054,296 - 45,840,698 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113032   ⟹   ENSRNOP00000091110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl745,054,296 - 45,840,698 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114741   ⟹   ENSRNOP00000084644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl745,054,296 - 45,208,664 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119133   ⟹   ENSRNOP00000096716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl745,054,296 - 45,392,259 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119636   ⟹   ENSRNOP00000095548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl745,054,296 - 45,392,259 (-)Ensembl
RefSeq Acc Id: NM_001191782   ⟹   NP_001178711
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,940,670 - 47,278,625 (-)NCBI
mRatBN7.2745,054,296 - 45,392,259 (-)NCBI
Rnor_6.0752,164,805 - 52,508,145 (-)NCBI
Rnor_5.0752,174,059 - 52,510,816 (-)NCBI
Celera741,897,661 - 42,222,850 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079109   ⟹   XP_038935037
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,281,090 (-)NCBI
mRatBN7.2745,052,206 - 45,394,696 (-)NCBI
RefSeq Acc Id: XM_039079110   ⟹   XP_038935038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,281,090 (-)NCBI
mRatBN7.2745,052,206 - 45,394,696 (-)NCBI
RefSeq Acc Id: XM_039079111   ⟹   XP_038935039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,280,088 (-)NCBI
mRatBN7.2745,052,206 - 45,394,694 (-)NCBI
RefSeq Acc Id: XM_039079112   ⟹   XP_038935040
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,281,090 (-)NCBI
mRatBN7.2745,052,206 - 45,394,696 (-)NCBI
RefSeq Acc Id: XM_039079113   ⟹   XP_038935041
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,281,089 (-)NCBI
mRatBN7.2745,052,206 - 45,394,696 (-)NCBI
RefSeq Acc Id: XM_039079114   ⟹   XP_038935042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,726,839 (-)NCBI
mRatBN7.2745,052,206 - 45,840,471 (-)NCBI
RefSeq Acc Id: XM_039079115   ⟹   XP_038935043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,726,839 (-)NCBI
mRatBN7.2745,052,206 - 45,840,471 (-)NCBI
RefSeq Acc Id: XM_039079116   ⟹   XP_038935044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,222,236 (-)NCBI
mRatBN7.2745,052,206 - 45,335,873 (-)NCBI
RefSeq Acc Id: XM_039079117   ⟹   XP_038935045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,205,438 (-)NCBI
mRatBN7.2745,052,206 - 45,319,051 (-)NCBI
RefSeq Acc Id: XM_039079118   ⟹   XP_038935046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,278,360 (-)NCBI
mRatBN7.2745,052,206 - 45,391,982 (-)NCBI
RefSeq Acc Id: XM_039079119   ⟹   XP_038935047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,104,195 (-)NCBI
mRatBN7.2745,052,206 - 45,214,897 (-)NCBI
RefSeq Acc Id: XM_063263475   ⟹   XP_063119545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,726,839 (-)NCBI
RefSeq Acc Id: XM_063263477   ⟹   XP_063119547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,726,839 (-)NCBI
RefSeq Acc Id: XM_063263478   ⟹   XP_063119548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,104,195 (-)NCBI
RefSeq Acc Id: XM_063263479   ⟹   XP_063119549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8746,938,577 - 47,104,194 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001178711   ⟸   NM_001191782
- UniProtKB: A0A0G2JZB7 (UniProtKB/TrEMBL),   A0A8I6AR69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070987   ⟸   ENSRNOT00000082100
RefSeq Acc Id: XP_038935043   ⟸   XM_039079115
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AFJ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935042   ⟸   XM_039079114
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AFJ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935038   ⟸   XM_039079110
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ANV3 (UniProtKB/TrEMBL),   A0A8I6AR69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935037   ⟸   XM_039079109
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ANV3 (UniProtKB/TrEMBL),   A0A8I6AR69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935041   ⟸   XM_039079113
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AR69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935040   ⟸   XM_039079112
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AR69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935039   ⟸   XM_039079111
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AR69 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935046   ⟸   XM_039079118
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZNK3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935044   ⟸   XM_039079116
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZNK3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935045   ⟸   XM_039079117
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZNK3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935047   ⟸   XM_039079119
- Peptide Label: isoform X10
- UniProtKB: A0A8I6A0K3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000078833   ⟸   ENSRNOT00000108591
RefSeq Acc Id: ENSRNOP00000091110   ⟸   ENSRNOT00000113032
RefSeq Acc Id: ENSRNOP00000084644   ⟸   ENSRNOT00000114741
RefSeq Acc Id: ENSRNOP00000096716   ⟸   ENSRNOT00000119133
RefSeq Acc Id: ENSRNOP00000095548   ⟸   ENSRNOT00000119636
RefSeq Acc Id: ENSRNOP00000079901   ⟸   ENSRNOT00000097268
RefSeq Acc Id: XP_063119545   ⟸   XM_063263475
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063119547   ⟸   XM_063263477
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063119548   ⟸   XM_063263478
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063119549   ⟸   XM_063263479
- Peptide Label: isoform X12
Protein Domains
AAA+ ATPase   Calponin-homology (CH)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JZB7-F1-model_v2 AlphaFold A0A0G2JZB7 1-2254 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695184
Promoter ID:EPDNEW_R5709
Type:multiple initiation site
Name:Nav3_1
Description:neuron navigator 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0752,404,797 - 52,404,857EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306259 AgrOrtholog
BioCyc Gene G2FUF-34147 BioCyc
Ensembl Genes ENSRNOG00000052157 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082100 ENTREZGENE
  ENSRNOT00000082100.2 UniProtKB/TrEMBL
  ENSRNOT00000097268.1 UniProtKB/TrEMBL
  ENSRNOT00000108591.1 UniProtKB/TrEMBL
  ENSRNOT00000113032.1 UniProtKB/TrEMBL
  ENSRNOT00000114741.1 UniProtKB/TrEMBL
  ENSRNOT00000119133.1 UniProtKB/TrEMBL
  ENSRNOT00000119636.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  Calponin-like_dom_sf UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  Nav/unc-53 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:314814 UniProtKB/TrEMBL
NCBI Gene 314814 ENTREZGENE
PANTHER NEURON NAVIGATOR 3 UniProtKB/TrEMBL
  PTHR12784 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PhenoGen Nav3 PhenoGen
PROSITE PS50021 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000052157 RatGTEx
SMART AAA UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP Calponin-homology UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JZB7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZLL1_RAT UniProtKB/TrEMBL
  A0A8I5ZNK3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0K3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFJ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ANV3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AR69 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Nav3  neuron navigator 3  RGD1306259_predicted  similar to neuron navigator 3; pore membrane and/or filament interacting like protein 1; steerin 3 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1306259_predicted  similar to neuron navigator 3; pore membrane and/or filament interacting like protein 1; steerin 3 (predicted)  LOC314814_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314814_predicted  similar to neuron navigator 3; pore membrane and/or filament interacting like protein 1; steerin 3 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL