Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-colchicine | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Colchicine results in decreased expression of PLXNB2 mRNA | CTD | PMID:24211769 | 1,2-dimethylhydrazine | multiple interactions | ISO | Plxnb2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PLXNB2 mRNA | CTD | PMID:22206623 | 14-Deoxy-11,12-didehydroandrographolide | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | 14-deoxy-11 and 12-didehydroandrographolide results in decreased expression of PLXNB2 mRNA | CTD | PMID:22101062 | 17beta-estradiol | affects expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Estradiol affects the expression of PLXNB2 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PLXNB2 mRNA | CTD | PMID:15652763 and PMID:33956508 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PLXNB2 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PLXNB2 mRNA | CTD | PMID:17035482 | 2-methylcholine | affects expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of PLXNB2 mRNA | CTD | PMID:21179406 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PLXNB2 mRNA | CTD | PMID:20188158 | 4,4'-sulfonyldiphenol | increases methylation | ISO | Plxnb2 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of PLXNB2 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | bisphenol S affects the expression of PLXNB2 protein | CTD | PMID:31945527 | 4-hydroxyphenyl retinamide | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of PLXNB2 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PLXNB2 mRNA | CTD | PMID:24780913 | acrolein | multiple interactions | ISO | PLXNB2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PLXNB2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PLXNB2 mRNA | CTD | PMID:32699268 | acrylamide | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of PLXNB2 mRNA | CTD | PMID:32763439 | adenine | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Adenine results in decreased expression of PLXNB2 mRNA | CTD | PMID:24211769 | aflatoxin B1 | affects expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of PLXNB2 protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of PLXNB2 mRNA | CTD | PMID:21632981 | Aflatoxin B2 alpha | decreases methylation | ISO | PLXNB2 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of PLXNB2 intron | CTD | PMID:30157460 | alpha-pinene | multiple interactions | ISO | PLXNB2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PLXNB2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PLXNB2 mRNA | CTD | PMID:32699268 | antirheumatic drug | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of PLXNB2 mRNA | CTD | PMID:24449571 | aristolochic acid A | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of PLXNB2 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | PLXNB2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PLXNB2 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | PLXNB2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of PLXNB2 gene | CTD | PMID:25304211 | arsenite(3-) | decreases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | arsenite results in decreased expression of PLXNB2 mRNA | CTD | PMID:33053406 | arsenous acid | decreases response to substance | ISO | PLXNB2 (Homo sapiens) | 6480464 | PLXNB2 protein results in decreased susceptibility to Arsenic Trioxide | CTD | PMID:20707922 | benzo[a]pyrene | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PLXNB2 mRNA | CTD | PMID:21632981 | benzo[a]pyrene | decreases methylation | ISO | Plxnb2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of PLXNB2 5' UTR more ... | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | PLXNB2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PLXNB2 5' UTR | CTD | PMID:27901495 | benzo[e]pyrene | decreases methylation | ISO | PLXNB2 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of PLXNB2 intron | CTD | PMID:30157460 | bisphenol A | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PLXNB2 mRNA | CTD | PMID:26063408 and PMID:33221593 | bisphenol A | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of PLXNB2 protein | CTD | PMID:34186270 | bisphenol A | affects methylation | ISO | PLXNB2 (Homo sapiens) | 6480464 | bisphenol A affects the methylation of PLXNB2 gene | CTD | PMID:31601247 | bisphenol A | affects expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of PLXNB2 mRNA | CTD | PMID:30903817 | bisphenol A | increases methylation | ISO | PLXNB2 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of PLXNB2 promoter | CTD | PMID:27271280 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PLXNB2 gene | CTD | PMID:28505145 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PLXNB2 mRNA | CTD | PMID:25181051 and PMID:32145629 | Bisphenol B | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of PLXNB2 protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of PLXNB2 protein | CTD | PMID:34186270 | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of PLXNB2 mRNA | CTD | PMID:19167457 | cadmium atom | multiple interactions | ISO | Plxnb2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PLXNB2 mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | Plxnb2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PLXNB2 mRNA | CTD | PMID:37325564 | carbamazepine | affects expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of PLXNB2 mRNA | CTD | PMID:25979313 | carbon nanotube | decreases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of PLXNB2 mRNA | CTD | PMID:25620056 | cisplatin | multiple interactions | ISO | PLXNB2 (Homo sapiens) | 6480464 | [Piroxicam co-treated with Cisplatin] results in increased expression of PLXNB2 mRNA | CTD | PMID:21858171 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of PLXNB2 mRNA | CTD | PMID:20187946 | copper atom | multiple interactions | ISO | PLXNB2 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of PLXNB2 mRNA | CTD | PMID:24690739 | copper(0) | multiple interactions | ISO | PLXNB2 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of PLXNB2 mRNA | CTD | PMID:24690739 | coumestrol | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of PLXNB2 mRNA | CTD | PMID:19167446 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of PLXNB2 mRNA | CTD | PMID:26577399 | diarsenic trioxide | decreases response to substance | ISO | PLXNB2 (Homo sapiens) | 6480464 | PLXNB2 protein results in decreased susceptibility to Arsenic Trioxide | CTD | PMID:20707922 | dioxygen | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of PLXNB2 mRNA | CTD | PMID:24205000 | disulfiram | multiple interactions | ISO | PLXNB2 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in increased expression of PLXNB2 mRNA | CTD | PMID:24690739 | doxorubicin | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of PLXNB2 mRNA | CTD | PMID:29803840 | elemental selenium | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Selenium results in increased expression of PLXNB2 mRNA | CTD | PMID:19244175 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PLXNB2 mRNA | CTD | PMID:29391264 | ethanol | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Ethanol results in increased expression of PLXNB2 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of PLXNB2 mRNA | CTD | PMID:23649840 | fenamidone | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | fenamidone results in increased expression of PLXNB2 mRNA | CTD | PMID:27029645 | fenthion | decreases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Fenthion results in decreased expression of PLXNB2 mRNA | CTD | PMID:34813904 | folic acid | multiple interactions | ISO | Plxnb2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PLXNB2 mRNA | CTD | PMID:22206623 | formaldehyde | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of PLXNB2 mRNA | CTD | PMID:23649840 | hypochlorous acid | decreases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Hypochlorous Acid results in decreased expression of PLXNB2 mRNA | CTD | PMID:19376150 | inulin | multiple interactions | ISO | Plxnb2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PLXNB2 mRNA | CTD | PMID:36331819 | isobutanol | multiple interactions | ISO | PLXNB2 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of PLXNB2 mRNA | CTD | PMID:29432896 | ivermectin | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PLXNB2 protein | CTD | PMID:32959892 | lead(0) | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Lead results in decreased expression of PLXNB2 mRNA | CTD | PMID:19921347 | lead(0) | affects splicing | ISO | PLXNB2 (Homo sapiens) | 6480464 | Lead affects the splicing of PLXNB2 mRNA | CTD | PMID:28903495 | methapyrilene | decreases methylation | ISO | PLXNB2 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of PLXNB2 intron | CTD | PMID:30157460 | methyl methanesulfonate | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of PLXNB2 mRNA | CTD | PMID:23649840 | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | Plxnb2 (Mus musculus) | 6480464 | Ethylnitrosourea results in increased mutagenesis of PLXNB2 intron and Ethylnitrosourea results in increased mutagenesis of PLXNB2 mRNA | CTD | PMID:27776689 | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of PLXNB2 mRNA | CTD | PMID:24136188 | nickel atom | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Nickel results in decreased expression of PLXNB2 mRNA | CTD | PMID:23195993 | ozone | multiple interactions | ISO | PLXNB2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PLXNB2 mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | ISO | Plxnb2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of PLXNB2 mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of PLXNB2 mRNA | CTD | PMID:21420995 and PMID:26690555 | paracetamol | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PLXNB2 mRNA | CTD | PMID:22230336 | perfluorohexanesulfonic acid | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of PLXNB2 mRNA | CTD | PMID:25812627 | perfluorononanoic acid | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of PLXNB2 mRNA | CTD | PMID:25812627 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Plxnb2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PLXNB2 mRNA | CTD | PMID:36331819 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of PLXNB2 mRNA | CTD | PMID:25812627 | perfluorooctanoic acid | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of PLXNB2 mRNA | CTD | PMID:25812627 | phenytoin | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Phenytoin results in decreased expression of PLXNB2 mRNA | CTD | PMID:14741686 | pirinixic acid | decreases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of PLXNB2 mRNA | CTD | PMID:18445702 | piroxicam | multiple interactions | ISO | PLXNB2 (Homo sapiens) | 6480464 | [Piroxicam co-treated with Cisplatin] results in increased expression of PLXNB2 mRNA | CTD | PMID:21858171 | quercetin | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of PLXNB2 mRNA | CTD | PMID:21632981 | resveratrol | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | resveratrol results in increased expression of PLXNB2 protein | CTD | PMID:25505154 | selenium atom | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Selenium results in increased expression of PLXNB2 mRNA | CTD | PMID:19244175 | serpentine asbestos | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Asbestos and Serpentine results in increased expression of PLXNB2 mRNA | CTD | PMID:16251409 | sodium arsenite | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of PLXNB2 mRNA | CTD | PMID:36209798 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of PLXNB2 mRNA | CTD | PMID:19281266 | tert-butyl hydroperoxide | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of PLXNB2 mRNA | CTD | PMID:15336504 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of PLXNB2 mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of PLXNB2 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of PLXNB2 mRNA | CTD | PMID:23557971 | triclosan | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Triclosan results in increased expression of PLXNB2 mRNA | CTD | PMID:30510588 | tungsten | decreases expression | ISO | Plxnb2 (Mus musculus) | 6480464 | Tungsten results in decreased expression of PLXNB2 mRNA | CTD | PMID:30912803 | valproic acid | decreases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PLXNB2 mRNA | CTD | PMID:29154799 | valproic acid | increases expression | ISO | PLXNB2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PLXNB2 mRNA | CTD | PMID:23179753 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of PLXNB2 mRNA | CTD | PMID:23034163 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
|
| You must be logged in to use this feature |
| {{ loginError }} |
|
|
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
|
||||||||||
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
