Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TFCP2L1 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TFCP2L1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TFCP2L1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of TFCP2L1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of TFCP2L1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | affects expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of TFCP2L1 mRNA | CTD | PMID:17555576 | 17beta-estradiol | affects expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Estradiol affects the expression of TFCP2L1 mRNA | CTD | PMID:15598610 | 17beta-estradiol | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of TFCP2L1 mRNA | CTD | PMID:31614463 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of TFCP2L1 mRNA | CTD | PMID:26496021 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin affects the methylation of TFCP2L1 intron] which results in decreased expression of TFCP2L1 mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of TFCP2L1 mRNA | CTD | PMID:17942748 and PMID:33017471 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TFCP2L1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TFCP2L1 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TFCP2L1 mRNA | CTD | PMID:26290441 | 2-hydroxypropanoic acid | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TFCP2L1 mRNA | CTD | PMID:30851411 | 3,7-dihydropurine-6-thione | decreases expression | EXP | | 6480464 | Mercaptopurine results in decreased expression of TFCP2L1 mRNA | CTD | PMID:23358152 | 4-hydroxyphenyl retinamide | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Fenretinide results in increased expression of TFCP2L1 mRNA | CTD | PMID:28973697 | 5-fluorouracil | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Fluorouracil results in increased expression of TFCP2L1 protein | CTD | PMID:21296659 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TFCP2L1 mRNA | CTD | PMID:30047161 | acetic acid | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Acetic Acid results in decreased expression of TFCP2L1 protein | CTD | PMID:21296659 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of TFCP2L1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of TFCP2L1 mRNA | CTD | PMID:25378103 | all-trans-retinoic acid | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TFCP2L1 mRNA | CTD | PMID:36189433 | antirheumatic drug | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TFCP2L1 mRNA | CTD | PMID:24449571 | aristolochic acid A | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TFCP2L1 mRNA | CTD | PMID:33212167 | Aroclor 1254 | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of TFCP2L1 mRNA | CTD | PMID:25270620 | benzo[a]pyrene | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TFCP2L1 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | affects methylation | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TFCP2L1 intron | CTD | PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TFCP2L1 3' UTR | CTD | PMID:27901495 | benzo[b]fluoranthene | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of TFCP2L1 mRNA | CTD | PMID:26377693 | benzo[b]fluoranthene | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TFCP2L1 mRNA | CTD | PMID:27858113 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of TFCP2L1 mRNA | CTD | PMID:26496021 | bisphenol A | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TFCP2L1 mRNA | CTD | PMID:32156529 and PMID:35598803 | bisphenol A | decreases methylation | ISO | TFCP2L1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of TFCP2L1 gene | CTD | PMID:31601247 | bisphenol A | affects methylation | ISO | Tfcp2l1 (Mus musculus) | 6480464 | bisphenol A affects the methylation of TFCP2L1 promoter | CTD | PMID:27334623 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TFCP2L1 mRNA | CTD | PMID:25181051 | butanal | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of TFCP2L1 mRNA | CTD | PMID:26079696 | calcitriol | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of TFCP2L1 mRNA | CTD | PMID:26485663 | carbon nanotube | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | TFCP2L1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TFCP2L1 gene] | CTD | PMID:28238834 | chlordecone | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Chlordecone results in increased expression of TFCP2L1 mRNA | CTD | PMID:33711761 | chrysene | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TFCP2L1 mRNA | CTD | PMID:27858113 | ciguatoxin CTX1B | affects expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of TFCP2L1 mRNA | CTD | PMID:18353800 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of TFCP2L1 mRNA | CTD | PMID:24386269 | copper(II) sulfate | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of TFCP2L1 mRNA | CTD | PMID:19549813 | deoxynivalenol | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | deoxynivalenol results in decreased expression of TFCP2L1 protein | CTD | PMID:33890134 | dibenz[a,h]anthracene | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | diethylstilbestrol | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Diethylstilbestrol results in decreased expression of TFCP2L1 mRNA | CTD | PMID:17394237 | dimethylarsinous acid | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | dimethylarsinous acid results in decreased expression of TFCP2L1 mRNA | CTD | PMID:23876855 | dorsomorphin | multiple interactions | ISO | TFCP2L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of TFCP2L1 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | entinostat results in increased expression of TFCP2L1 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | TFCP2L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFCP2L1 mRNA | CTD | PMID:27188386 | ethanol | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Ethanol results in increased expression of TFCP2L1 mRNA | CTD | PMID:28986285 | ethanol | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Ethanol results in increased expression of TFCP2L1 mRNA | CTD | PMID:30319688 | ethanol | affects expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Ethanol affects the expression of TFCP2L1 mRNA | CTD | PMID:30319688 | fenthion | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of TFCP2L1 mRNA | CTD | PMID:34813904 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TFCP2L1 mRNA | CTD | PMID:25539665 | glycidyl methacrylate | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | glycidyl methacrylate results in increased expression of TFCP2L1 protein | CTD | PMID:36641056 | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of TFCP2L1 mRNA | CTD | PMID:22641619 | mercaptopurine | decreases expression | EXP | | 6480464 | Mercaptopurine results in decreased expression of TFCP2L1 mRNA | CTD | PMID:23358152 | methylmercury chloride | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TFCP2L1 mRNA | CTD | PMID:23903816 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TFCP2L1 mRNA | CTD | PMID:36189433 | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Ethylnitrosourea results in increased mutagenesis of TFCP2L1 intron | CTD | PMID:27776689 | nickel atom | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of TFCP2L1 mRNA | CTD | PMID:24768652 and PMID:25583101 | okadaic acid | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Okadaic Acid results in increased expression of TFCP2L1 mRNA | CTD | PMID:25270620 | ozone | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TFCP2L1 mRNA | CTD | PMID:34911549 | panobinostat | multiple interactions | ISO | TFCP2L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFCP2L1 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | panobinostat results in increased expression of TFCP2L1 mRNA | CTD | PMID:26272509 | paracetamol | affects expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TFCP2L1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TFCP2L1 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TFCP2L1 mRNA | CTD | PMID:36331819 | phenobarbital | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of TFCP2L1 mRNA] | CTD | PMID:19482888 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of TFCP2L1 mRNA | CTD | PMID:30047161 | phenobarbital | affects expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of TFCP2L1 mRNA | CTD | PMID:23091169 | phenobarbital | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of TFCP2L1 mRNA | CTD | PMID:19270015 and PMID:19482888 | PhIP | decreases expression | EXP | | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of TFCP2L1 mRNA | CTD | PMID:15215175 | progesterone | affects expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Progesterone affects the expression of TFCP2L1 mRNA | CTD | PMID:17251523 | progesterone | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Progesterone results in decreased expression of TFCP2L1 mRNA | CTD | PMID:21540246 | propanal | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of TFCP2L1 mRNA | CTD | PMID:26079696 | purine-6-thiol | decreases expression | EXP | | 6480464 | Mercaptopurine results in decreased expression of TFCP2L1 mRNA | CTD | PMID:23358152 | rac-lactic acid | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TFCP2L1 mRNA | CTD | PMID:30851411 | rotenone | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Rotenone results in increased expression of TFCP2L1 mRNA | CTD | PMID:32937126 | SB 431542 | multiple interactions | ISO | TFCP2L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of TFCP2L1 mRNA and Silicon Dioxide results in decreased expression of TFCP2L1 mRNA | CTD | PMID:25351596 and PMID:25895662 | sodium arsenite | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TFCP2L1 mRNA | CTD | PMID:34032870 | sodium arsenite | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TFCP2L1 mRNA | CTD | PMID:37682722 | tamoxifen | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Tamoxifen results in decreased expression of TFCP2L1 mRNA | CTD | PMID:25123088 | tamoxifen | affects expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of TFCP2L1 mRNA | CTD | PMID:17555576 | testosterone | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | Testosterone results in increased expression of TFCP2L1 mRNA | CTD | PMID:20403060 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TFCP2L1 mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TFCP2L1 mRNA | CTD | PMID:31150632 | tetraphene | decreases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of TFCP2L1 mRNA | CTD | PMID:26377693 | tetraphene | multiple interactions | ISO | Tfcp2l1 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of TFCP2L1 mRNA | CTD | PMID:27858113 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TFCP2L1 mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of TFCP2L1 mRNA | CTD | PMID:23557971 | trichostatin A | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of TFCP2L1 mRNA | CTD | PMID:24935251 | triptonide | increases expression | ISO | Tfcp2l1 (Mus musculus) | 6480464 | triptonide results in increased expression of TFCP2L1 mRNA | CTD | PMID:33045310 | urethane | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of TFCP2L1 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TFCP2L1 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | TFCP2L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFCP2L1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TFCP2L1 mRNA | CTD | PMID:26272509 and PMID:28001369 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of TFCP2L1 mRNA | CTD | PMID:20566332 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of TFCP2L1 mRNA | CTD | PMID:23034163 | zoledronic acid | decreases expression | ISO | TFCP2L1 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of TFCP2L1 mRNA | CTD | PMID:24714768 | |