Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | decreases expression | ISO | SCEL (Homo sapiens) | 6480464 | Estradiol results in decreased expression of SCEL mRNA | CTD | PMID:23019147 | 17beta-estradiol | multiple interactions | ISO | SCEL (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of SCEL mRNA | CTD | PMID:30165855 | 17beta-estradiol 3-benzoate | increases methylation | EXP | | 6480464 | estradiol 3-benzoate results in increased methylation of SCEL promoter | CTD | PMID:27415467 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:27291303 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Scel (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SCEL mRNA | CTD | PMID:17035482 and PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SCEL mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Scel (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SCEL mRNA | CTD | PMID:21570461 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SCEL mRNA | CTD | PMID:24780913 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of SCEL mRNA | CTD | PMID:28959563 | all-trans-retinoic acid | increases expression | ISO | SCEL (Homo sapiens) | 6480464 | Tretinoin results in increased expression of SCEL mRNA | CTD | PMID:16249480 | aristolochic acid A | decreases expression | ISO | SCEL (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SCEL mRNA and aristolochic acid I results in decreased expression of SCEL protein | CTD | PMID:33212167 | arsane | decreases expression | ISO | Scel (Mus musculus) | 6480464 | Arsenic results in decreased expression of SCEL mRNA | CTD | PMID:19654921 | arsenic atom | decreases expression | ISO | Scel (Mus musculus) | 6480464 | Arsenic results in decreased expression of SCEL mRNA | CTD | PMID:19654921 | benzo[a]pyrene | decreases methylation | ISO | SCEL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SCEL promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | SCEL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SCEL 3' UTR | CTD | PMID:27901495 | Benzo[k]fluoranthene | decreases expression | ISO | Scel (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of SCEL mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SCEL mRNA | CTD | PMID:25181051 more ... | bisphenol A | increases expression | ISO | Scel (Mus musculus) | 6480464 | bisphenol A results in increased expression of SCEL mRNA | CTD | PMID:32156529 | bisphenol A | increases expression | ISO | SCEL (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SCEL mRNA | CTD | PMID:29275510 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SCEL gene | CTD | PMID:28505145 | bisphenol F | increases expression | ISO | Scel (Mus musculus) | 6480464 | bisphenol F results in increased expression of SCEL mRNA | CTD | PMID:30951980 | cadmium atom | increases expression | ISO | SCEL (Homo sapiens) | 6480464 | Cadmium results in increased expression of SCEL mRNA | CTD | PMID:21120746 | calcitriol | decreases expression | ISO | SCEL (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of SCEL mRNA | CTD | PMID:16002434 | carbon nanotube | decreases expression | ISO | Scel (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | SCEL (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SCEL gene] | CTD | PMID:28238834 | chlordecone | increases expression | ISO | Scel (Mus musculus) | 6480464 | Chlordecone results in increased expression of SCEL mRNA | CTD | PMID:33711761 | chlorpyrifos | increases expression | ISO | Scel (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SCEL mRNA | CTD | PMID:37019170 | copper atom | multiple interactions | ISO | SCEL (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of SCEL mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | SCEL (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of SCEL mRNA | CTD | PMID:20971185 | copper(II) sulfate | increases expression | ISO | SCEL (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SCEL mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases expression | ISO | Scel (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of SCEL mRNA | CTD | PMID:29279043 | cylindrospermopsin | increases expression | ISO | SCEL (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of SCEL mRNA | CTD | PMID:24921660 | decabromodiphenyl ether | decreases expression | EXP | | 6480464 | decabromobiphenyl ether results in decreased expression of SCEL mRNA | CTD | PMID:23640034 | dexamethasone | increases expression | ISO | SCEL (Homo sapiens) | 6480464 | Dexamethasone results in increased expression of SCEL mRNA | CTD | PMID:16144937 | dimethylarsinic acid | multiple interactions | ISO | Scel (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SCEL mRNA | CTD | PMID:34876320 | diuron | decreases expression | ISO | SCEL (Homo sapiens) | 6480464 | Diuron metabolite results in decreased expression of SCEL mRNA | CTD | PMID:24172598 | dorsomorphin | multiple interactions | ISO | SCEL (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCEL mRNA | CTD | PMID:27188386 | ethylparaben | increases expression | ISO | SCEL (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of SCEL mRNA | CTD | PMID:37690743 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of SCEL mRNA | CTD | PMID:30307764 | genistein | decreases expression | ISO | SCEL (Homo sapiens) | 6480464 | Genistein results in decreased expression of SCEL mRNA | CTD | PMID:23019147 | methylarsonic acid | multiple interactions | ISO | Scel (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SCEL mRNA | CTD | PMID:34876320 | N-nitrosodiethylamine | increases expression | ISO | Scel (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of SCEL mRNA | CTD | PMID:24535843 | ozone | multiple interactions | ISO | Scel (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of SCEL mRNA | CTD | PMID:34911549 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SCEL mRNA | CTD | PMID:33387578 | phenylmercury acetate | multiple interactions | ISO | SCEL (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCEL mRNA | CTD | PMID:27188386 | SB 431542 | multiple interactions | ISO | SCEL (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCEL mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | Scel (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of SCEL mRNA | CTD | PMID:29203145 | sodium arsenate | multiple interactions | ISO | Scel (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SCEL mRNA | CTD | PMID:34876320 | sodium arsenite | decreases expression | ISO | SCEL (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SCEL mRNA | CTD | PMID:28595984 and PMID:34032870 | sodium arsenite | decreases expression | ISO | Scel (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of SCEL mRNA | CTD | PMID:37682722 | sodium arsenite | multiple interactions | ISO | Scel (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SCEL mRNA | CTD | PMID:34876320 | sulforaphane | decreases expression | ISO | Scel (Mus musculus) | 6480464 | sulforaphane results in decreased expression of SCEL mRNA | CTD | PMID:30529165 | tetrachloromethane | affects expression | ISO | Scel (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of SCEL mRNA | CTD | PMID:17484886 | titanium dioxide | decreases expression | ISO | Scel (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of SCEL mRNA | CTD | PMID:23557971 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of SCEL mRNA | CTD | PMID:28181387 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SCEL mRNA | CTD | PMID:33387578 | trovafloxacin | decreases expression | ISO | Scel (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of SCEL mRNA | CTD | PMID:35537566 | valproic acid | increases expression | ISO | SCEL (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SCEL mRNA | CTD | PMID:27188386 | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of SCEL gene | CTD | PMID:31079544 | zoledronic acid | decreases expression | ISO | SCEL (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of SCEL mRNA | CTD | PMID:24714768 | |