Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Selenok (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SELENOK mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Selenok (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SELK mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Estradiol results in increased expression of SELENOK mRNA | CTD | PMID:20106945 | 17beta-estradiol | multiple interactions | ISO | SELENOK (Homo sapiens) | 6480464 | [Estradiol co-treated with Norethindrone Acetate] results in increased expression of SELENOK mRNA | CTD | PMID:22217510 | 17beta-estradiol | decreases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Estradiol results in decreased expression of SELENOK mRNA | CTD | PMID:23019147 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of SELK mRNA | CTD | PMID:29581250 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31826744 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Selenok (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SELENOK mRNA | CTD | PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Selenok (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of SELENOK mRNA and AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SELENOK mRNA] | CTD | PMID:15034205 and PMID:16214954 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Selenok (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SELENOK mRNA | CTD | PMID:15034205 and PMID:18796159 | 2-palmitoylglycerol | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of SELENOK mRNA | CTD | PMID:37199045 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Selenok (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of SELENOK mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SELENOK mRNA | CTD | PMID:36041667 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of SELK mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | SELENOK (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SELENOK gene | CTD | PMID:27153756 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SELENOK mRNA | CTD | PMID:16483693 | arsenic acid | decreases expression | ISO | Selenok (Mus musculus) | 6480464 | arsenic acid results in decreased expression of SELENOK mRNA | CTD | PMID:19429247 | arsenite(3-) | decreases expression | ISO | Selenok (Mus musculus) | 6480464 | arsenite results in decreased expression of SELENOK mRNA | CTD | PMID:19429247 | arsenite(3-) | multiple interactions | ISO | SELENOK (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to SELENOK mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | ISO | Selenok (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SELENOK mRNA | CTD | PMID:15034205 and PMID:22228805 | benzo[a]pyrene | decreases methylation | ISO | SELENOK (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SELK promoter | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | ISO | Selenok (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of SELENOK mRNA] | CTD | PMID:15034205 | Benzo[k]fluoranthene | increases expression | ISO | Selenok (Mus musculus) | 6480464 | benzo(k)fluoranthene results in increased expression of SELENOK mRNA | CTD | PMID:26377693 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SELENOK mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SELENOK mRNA | CTD | PMID:36041667 | bisphenol A | increases expression | ISO | Selenok (Mus musculus) | 6480464 | bisphenol A results in increased expression of SELENOK mRNA | CTD | PMID:33221593 | bisphenol A | affects expression | ISO | SELENOK (Homo sapiens) | 6480464 | bisphenol A affects the expression of SELK mRNA | CTD | PMID:30903817 | bisphenol F | multiple interactions | ISO | SELENOK (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of SELENOK gene | CTD | PMID:31601247 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SELENOK mRNA | CTD | PMID:36041667 | bortezomib | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Bortezomib results in increased expression of SELENOK mRNA | CTD | PMID:20977926 | CGP 52608 | multiple interactions | ISO | SELENOK (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SELK gene] | CTD | PMID:28238834 | ciguatoxin CTX1B | affects expression | ISO | Selenok (Mus musculus) | 6480464 | Ciguatoxins affects the expression of SELENOK mRNA | CTD | PMID:18353800 | cisplatin | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Cisplatin results in increased expression of SELENOK mRNA | CTD | PMID:19561079 | clobetasol | increases expression | ISO | Selenok (Mus musculus) | 6480464 | Clobetasol results in increased expression of SELENOK mRNA | CTD | PMID:27462272 | cobalt dichloride | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of SELENOK mRNA | CTD | PMID:19320972 | copper atom | multiple interactions | ISO | SELENOK (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of SELENOK mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | SELENOK (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of SELENOK mRNA | CTD | PMID:20971185 | copper(II) chloride | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | cupric chloride results in increased expression of SELENOK mRNA | CTD | PMID:17211630 | copper(II) sulfate | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SELENOK mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SELENOK mRNA | CTD | PMID:20106945 more ... | dibutyl phthalate | increases expression | ISO | Selenok (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of SELENOK mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | SELENOK (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SELENOK mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | ISO | Selenok (Mus musculus) | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of SELENOK mRNA] | CTD | PMID:22629407 | dioxygen | increases expression | ISO | Selenok (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of SELENOK mRNA | CTD | PMID:22629407 | disodium selenite | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of SELENOK mRNA | CTD | PMID:18175754 | diuron | decreases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Diuron results in decreased expression of SELENOK mRNA | CTD | PMID:35967413 | doxorubicin | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of SELENOK mRNA | CTD | PMID:29803840 | elemental selenium | affects expression | EXP | | 6480464 | Selenium affects the expression of SELENOK mRNA | CTD | PMID:19106321 | ethanol | affects splicing | ISO | Selenok (Mus musculus) | 6480464 | Ethanol affects the splicing of SELK mRNA | CTD | PMID:30319688 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SELENOK mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Selenok (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SELENOK mRNA | CTD | PMID:22206623 | fulvestrant | multiple interactions | ISO | SELENOK (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of SELENOK gene | CTD | PMID:31601247 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SELENOK mRNA | CTD | PMID:33387578 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of SELENOK mRNA | CTD | PMID:24136188 | miconazole | increases expression | ISO | Selenok (Mus musculus) | 6480464 | Miconazole results in increased expression of SELENOK mRNA | CTD | PMID:27462272 | nickel atom | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Nickel results in increased expression of SELENOK mRNA | CTD | PMID:23195993 | nickel sulfate | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of SELENOK mRNA | CTD | PMID:16780908 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of SELENOK mRNA | CTD | PMID:24136188 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SELENOK mRNA | CTD | PMID:33387578 | reactive oxygen species | affects abundance | ISO | SELENOK (Homo sapiens) | 6480464 | SELENOK protein affects the abundance of Reactive Oxygen Species | CTD | PMID:16962588 | selenium atom | affects expression | EXP | | 6480464 | Selenium affects the expression of SELENOK mRNA | CTD | PMID:19106321 | silver atom | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Silver results in increased expression of SELK mRNA | CTD | PMID:26014281 | silver(0) | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Silver results in increased expression of SELK mRNA | CTD | PMID:26014281 | sodium arsenite | decreases expression | ISO | SELENOK (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SELENOK mRNA | CTD | PMID:34032870 | tert-butyl hydroperoxide | decreases expression | ISO | Selenok (Mus musculus) | 6480464 | tert-Butylhydroperoxide results in decreased expression of SELENOK mRNA | CTD | PMID:15003993 | tunicamycin | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of SELK mRNA | CTD | PMID:29453283 | valproic acid | increases expression | ISO | SELENOK (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SELK mRNA | CTD | PMID:29154799 | valproic acid | affects expression | ISO | SELENOK (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SELENOK mRNA | CTD | PMID:25979313 | |