Kcnq1<sup>dfk</sup> (potassium voltage-gated channel subfamily Q member 1;deafness Kyoto) - Rat Genome Database

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Gene: Kcnq1dfk (potassium voltage-gated channel subfamily Q member 1;deafness Kyoto) Rattus norvegicus
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Symbol: Kcnq1dfk
Name: potassium voltage-gated channel subfamily Q member 1;deafness Kyoto
RGD ID: 12802344
Description: A naturally occurring deletion mutation arising on the genetic background of an inbred WTC strain. It is a 2040-bp deletion that included whole exon 7 and its flanking sequences of the Kcnq1 gene.
ASSOCIATED WITH abnormal cardiovascular system physiology; decreased body weight; impaired balance; ASSOCIATED WITH Achlorhydria; Deafness; hypertension
Type: allele  of Kcnq1  
Previously known as: Kcnq1^[dfk]; Kcnq1dfk
Is Marker For: Strains:   WTC-Kcnq1dfkKyo  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. WTC deafness Kyoto (dfk): a rat model for extensive investigations of Kcnq1 functions. Gohma H, etal., Physiol Genomics. 2006 Feb 14;24(3):198-206. Epub 2005 Dec 20.

Genomics

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Kcnq1dfk-var1 chr1 198374486 198376539 AAGATGTCTGGACAGCATGTGCCCTGGCTGTCAGTCCTGGGTATAACCTCTAGACCCCAATGTGTACTCGTATCCTCATGGTCCCTCAGCTCAGCCAGTGATACATGTTCCCTCGTGTGCATATGAGTGTGAACAGGTATCCTTGTCTCCATGTGAGGCACGTTTACAACTGTTATGCCCACATATGTAGAACAGGGTGGTCCCTTTAAAGGGTGCAACCATGAATGGTTTGTTATGCCCTCTGTTTGTGTAGGGCATGGATTTGTTTAAGGACAATGACATTGTGGGGAAGATTTCATATGGGCAGTTGTGGGAAAACACCAGGATGCAGCCAATATAGCATGGTGCAGCACCGAAGGGGTGGCCCTGTGGTGGCCTGGACCCAGCTGTGGACTGCTCTGTTGTTTGCCATCCAGGAAAAATTGACCTGTTGCTTCATGACCTGTTAACATACTGGCCAGAGTGACAAACTTGGCGCTGTGGGGTTACTCTTGCTGTCCCTGTCCCCTGCTCCCCTGCTGCAGTTGGTCAGAGTGCTTACCTATGTTGTAAGCATCCATGTCTACACCCACTCATATGTACCTATTAACTTCTGACTCCCATGCCTCCCTTGCCTTCCCCTGCTCTTTGGTGGTCACTGGGGAACAGTTGTGGTCCACAGCAGTTCATCTGGGAATGGAGTGGGTAGTGATGACAGTGGGCTGGGGGTGGGGTGAGGATCTTGAGGCTTTCTCTCTGAGCCCCACATTAGTTGGTATCTATTAGGTGGTGTTTCCCAAGCCCCATCCTTGTTGACCCTATTGGGCAGAGGTTCACTTAGAGGTTCTTATGTAGATCCTGGCTGGGTGGTTGTTACCTGGCCCCCAAGGGGTAACACTCTAGGTGTCTAGAGTAATCAGGCTATAAAGACCTTGAATGGGCAGGTTCTCCTATCACACTAACCTGCCTTGACTGAAGGGCTGATCTGGACAGTGTTGTGACCCCGAGGGCTGTGTGTTAGTGAATGTAACTATTCTGTTCGCCTGGCAGGCCCAAGGCAGCCTCATGGTGTGACCTAGCGGTTAGGCACAGCCAGGGTGGGCCCCTGAGTCGCTCATCAGAGGCCCCAGGAGTAAACCTCAGATGTCAGCAGGGGGTTGCGGGGGGTAGCCCCCCTCACTCCTATTGTCCCACTGCATACCCTGGACGCTGCTCTCCCACCAAGAAGGCTAGAGCCTTGTCTTATTCTCTCTGAAAAGGAAAAATAAAACATCTGGATCCCTGGGGTGGTGGCAGGAAGCAGCATGTCAGGCCATCCTGGGCTTTGTGGACTGCTGGCCTCAGTGGGAGCTTCTGGCCTCCAGGGGGCCAGTGCACTGCAACTCTGGTGGCCGGGGAAGGGATCCTTAGGATGGGGCAGGAAGCCTGGCCCCTGTGGGTGGGCTCTGAGTTCTTTGCCTGTCTTGCACCCCCCCAAGCTGTCTGCAACCCTAGGGCTGTGCCATCTGTGGTAATCAGAGTTGAGGGACTTAGGAGACTCAGAAACTTGAACGAACTCATCATATTGCTGTCCCTGGTACTTTCTCAGAACCATGCCTCATTACCCTGGTGGGCAGGGTTTTAAGTTGGTCTTCTTGTCATCAAGCCACTGTGTTAGGGCTGGCAGATGTCCCTTCTGAGGCTCTGAGCCTGCCAGCCACTGACTGCAGTCCTTTTTCTTTACAGGTCACAGTCACCACCATTGGCTACGGGGATAAGGTACCCCAGACATGGGTTGGGAAGACCATCGCCTCCTGTTTCTCTGTCTTCGCCATATCCTTCTTTGCACTCCCAGCGGTGGGTACCCATTAAGACCCCTCTCCCTTGTTCCCCACTCACCTTTGCCCCAACTCCTAGGCATTCCTTGAAGTAGAGTAAGGAGGCCTTGGCACTTCACAGAAGCAGCAAGGTACAGGGGAGCAGACTGGGCAGAACCTGCAGCTCCACAGCCTGGAGTGGCTCTGTCCTTTGACTTTTCCAAAAATCACTAACCTATGTCTACACATGTGTGTTACATGGGACACACGCCGGTTACT - deletion mRatBN7.2
Kcnq1dfk-var1 chr1 216377021 216379067 AAGATGTCTGGACAGCATGTGCCCTGGCTGTCAGTCCTGGGTATAACCTCTAGACCCCAATGTGTACTCGTATCCTCATGGTCCCTCAGCTCAGCCAGTGATACATGTTCCCTCGTGTGCATATGAGTGTGAACAGGTATCCTTGTCTCCATGTGAGGCACGTTTACAACTGTTATGCCCACATATGTAGAACAGGGTGGTCCCTTTAAAGGGTGCAACCATGAATGGTTTGTTATGCCCTCTGTTTGTGTAGGGCATGGATTTGTTTAAGGACAATGACATTGTGGGGAAGATTTCATATGGGCAGTTGTGGGAAAACACCAGGATGCAGCCAATATAGCATGGTGCAGCACCGAAGGGGTGGCCCTGTGGTGGCCTGGACCCAGCTGTGGACTGCTCTGTTGTTTGCCATCCAGGAAAAATTGACCTGTTGCTTCATGACCTGTTAACATACTGGCCAGAGTGACAAACTTGGCGCTGTGGGGTTACTCTTGCTGTCCCTGTCCCCTGCTCCCCTGCTGCAGTTGGTCAGAGTGCTTACCTATGTTGTAAGCATCCATGTCTACACCCACTCATATGTACCTATTAACTTCTGACTCCCATGCCTCCCTTGCCTTCCCCTGCTCTTTGGTGGTCACTGGGGAACAGTTGTGGTCCACAGCAGTTCATCTGGGAATGGAGTGGGTAGTGATGACAGTGGGCTGGGGGTGGGGTGAGGATCTTGAGGCTTTCTCTCTGAGCCCCACATTAGTTGGTATCTATTAGGTGGTGTTTCCCAAGCCCCATCCTTGTTGACCCTATTGGGCAGAGGTTCACTTAGAGGTTCTTATGTAGATCCTGGCTGGGTGGTTGTTACCTGGCCCCCAAGGGGTAACACTCTAGGTGTCTAGAGTAATCAGGCTATAAAGACCTTGAATGGGCAGGTTCTCCTATCACACTAACCTGCCTTGACTGAAGGGCTGATCTGGACAGTGTTGTGACCCCGAGGGCTGTGTGTTAGTGAATGTAACTATTCTGTTCGCCTGGCAGGCCCAAGGCAGCCTCATGGTGTGACCTAGCGGTTAGGCACAGCCAGGGTGGGCCCCTGAGTCGCTCATCAGAGGCCCCAGGAGTAAACCTCAGATGTCAGCAGGGGGTTGCGGGGGGTAGCCCCCCTCACTCCTATTGTCCCACTGCATACCCTGGACGCTGCTCTCCCACCAAGAAGGCTAGAGCCTTGTCTTATTCTCTCTGAAAAGGAAAAATAAAACATCTGGATCCCTGGGGTGGTGGCAGGAAGCAGCATGTCAGGCCATCCTGGGCTTTGTGGACTGCTGGCCTCAGTGGGAGCTTCTGGCCTCCAGGGGGCCAGTGCACTGCAACTCTGGTGGCCGGGGAAGGGATCCTTAGGATGGGGCAGGAAGCCTGGCCCCTGTGGGTGGGCTCTGAGTTCTTTGCCTGTCTTGCACCCCCCCAAGCTGTCTGCAACCCTAGGGCTGTGCCATCTGTGGTAATCAGAGTTGAGGGACTTAGGAGACTCAGAAACTTGAACGAACTCATCATATTGCTGTCCCTGGTACTTTCTCAGAACCATGCCTCATTACCCTGGTGGGCAGGGTTTTAAGTTGGTCTTCTTGTCATCAAGCCACTGTGTTAGGGCTGGCAGATGTCCCTTCTGAGGCTCTGAGCCTGCCAGCCACTGACTGCAGTCCTTTTTCTTTACAGGTCACAGTCACCACCATTGGCTACGGGGATAAGGTACCCCAGACATGGGTTGGGAAGACCATCGCCTCCTGTTTCTCTGTCTTCGCCATATCCTTCTTTGCACTCCCAGCGGTGGGTACCCATTAAGACCCCTCTCCCTTGTTCCCCACTCACCTTTGCCCCAACTCCTAGGCATTCCTTGAAGTAGAGTAAGGAGGCCTTGGCACTTCACAGAAGCAGCAAGGTACAGGGGAGCAGACTGGGCAGAACCTGCAGCTCCACAGCCTGGAGTGGCTCTGTCCTTTGACTTTTCCAAAAATCACTAACCTATGTCTACACATGTGTGTTACATGGGACACACGCCGGTTACT - deletion Rnor_6.0

Related Rat Strains
The following Strains have been annotated to Kcnq1dfk
WTC-Kcnq1dfkKyo    


Expression


Sequence

Nucleotide Sequences


Additional Information