Ldlrap1 (low density lipoprotein receptor adaptor protein 1) - Rat Genome Database

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Gene: Ldlrap1 (low density lipoprotein receptor adaptor protein 1) Ictidomys tridecemlineatus
Analyze
Symbol: Ldlrap1
Name: low density lipoprotein receptor adaptor protein 1
RGD ID: 12727785
Description: ENCODES a protein that exhibits amyloid-beta binding (inferred); AP-1 adaptor complex binding (inferred); AP-2 adaptor complex binding (inferred); INVOLVED IN cholesterol homeostasis (ortholog); ASSOCIATED WITH autosomal recessive hypercholesterolemia (ortholog); familial hypercholesterolemia (ortholog); genetic disease (ortholog); FOUND IN axon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: low density lipoprotein receptor adapter protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,371,440 - 44,395,584 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,196,211 - 10,221,777 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,196,228 - 10,219,137 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ldlrap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,371,440 - 44,395,584 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,196,211 - 10,221,777 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,196,228 - 10,219,137 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LDLRAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38125,543,606 - 25,590,400 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl125,543,606 - 25,568,886 (+)EnsemblGRCh38hg38GRCh38
GRCh37125,870,097 - 25,895,377 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36125,742,663 - 25,767,964 (+)NCBINCBI36Build 36hg18NCBI36
Celera124,265,963 - 24,291,423 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,124,497 - 24,149,801 (+)NCBIHuRef
CHM1_1125,983,497 - 26,008,795 (+)NCBICHM1_1
T2T-CHM13v2.0125,380,944 - 25,427,735 (+)NCBIT2T-CHM13v2.0
Ldlrap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394134,468,865 - 134,495,342 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4134,468,865 - 134,495,335 (-)EnsemblGRCm39 Ensembl
GRCm384134,741,554 - 134,768,032 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,741,554 - 134,768,024 (-)EnsemblGRCm38mm10GRCm38
MGSCv374134,301,327 - 134,323,919 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364134,017,498 - 134,040,023 (-)NCBIMGSCv36mm8
Celera4132,929,656 - 132,952,236 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map467.09NCBI
Ldlrap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85152,239,296 - 152,262,290 (-)NCBIGRCr8
mRatBN7.25146,955,607 - 146,978,601 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,955,607 - 146,978,601 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,656,442 - 149,679,565 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05151,427,752 - 151,450,746 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05151,412,689 - 151,435,812 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,964,294 - 152,987,286 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,966,591 - 152,987,211 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,742,863 - 156,765,855 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,504,535 - 153,527,523 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5145,368,945 - 145,391,939 (-)NCBICelera
Cytogenetic Map5q36NCBI
Ldlrap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,081,556 - 5,095,182 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,081,919 - 5,102,349 (+)NCBIChiLan1.0ChiLan1.0
LDLRAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21201,263,219 - 201,336,642 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11200,376,406 - 200,434,513 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0124,809,535 - 24,852,394 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1125,871,874 - 25,920,550 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl125,878,358 - 25,903,336 (+)Ensemblpanpan1.1panPan2
LDLRAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,340,272 - 74,363,929 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,341,036 - 74,364,162 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,914,328 - 70,937,998 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,901,453 - 74,925,396 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,901,458 - 74,925,371 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,724,767 - 71,748,432 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,731,525 - 72,755,221 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,735,844 - 73,759,564 (-)NCBIUU_Cfam_GSD_1.0
LDLRAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,030,702 - 83,054,377 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,030,629 - 83,054,387 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2676,601,373 - 76,625,132 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LDLRAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120107,207,363 - 107,232,237 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20107,207,334 - 107,229,210 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660339,131,295 - 9,155,884 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ldlrap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247649,675,845 - 9,699,597 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247649,675,917 - 9,699,597 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005317622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000026410   ⟹   ENSSTOP00000021584
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647410,196,211 - 10,221,777 (+)Ensembl
RefSeq Acc Id: XM_005317622   ⟹   XP_005317679
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505844,371,440 - 44,395,584 (+)NCBI
SpeTri2.0NW_00493647410,196,228 - 10,219,137 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005317679 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000021584.1
GenBank Protein KAG3282444 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005317679   ⟸   XM_005317622
- UniProtKB: I3NB37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000021584   ⟸   ENSSTOT00000026410
Protein Domains
PID


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000019764 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000026410.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/TrEMBL
NCBI Gene Ldlrap1 ENTREZGENE
PANTHER LOW DENSITY LIPOPROTEIN RECEPTOR ADAPTER PROTEIN 1 UniProtKB/TrEMBL
  PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER UniProtKB/TrEMBL
Pfam PID UniProtKB/TrEMBL
PROSITE PID UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt I3NB37 ENTREZGENE, UniProtKB/TrEMBL