Tap2 (transporter 2, ATP binding cassette subfamily B member) - Rat Genome Database

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Gene: Tap2 (transporter 2, ATP binding cassette subfamily B member) Ictidomys tridecemlineatus
Analyze
Symbol: Tap2
Name: transporter 2, ATP binding cassette subfamily B member
RGD ID: 12725188
Description: ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); identical protein binding (ortholog); INVOLVED IN antigen processing and presentation of endogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent (ortholog); antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); Alzheimer's disease (ortholog); ankylosing spondylitis (ortholog); FOUND IN endoplasmic reticulum (ortholog); MHC class I peptide loading complex (ortholog); TAP complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: antigen peptide transporter 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,036,847 - 38,046,599 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,913,663 - 25,923,427 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,913,699 - 25,923,419 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,036,847 - 38,046,599 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,913,663 - 25,923,427 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,913,699 - 25,923,419 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,821,831 - 32,838,739 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,821,833 - 32,838,739 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,789,608 - 32,806,516 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,897,588 - 32,914,525 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,897,587 - 32,914,482NCBI
Celera634,338,665 - 34,355,440 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,531,964 - 32,548,753 (-)NCBIHuRef
CHM1_1632,790,604 - 32,807,372 (-)NCBICHM1_1
T2T-CHM13v2.0632,643,187 - 32,660,143 (-)NCBIT2T-CHM13v2.0
Tap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,423,453 - 34,435,295 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,422,501 - 34,435,295 (+)EnsemblGRCm39 Ensembl
GRCm381734,204,479 - 34,216,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,203,527 - 34,216,321 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,341,424 - 34,353,266 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,814,778 - 33,826,596 (+)NCBIMGSCv36mm8
Celera1736,957,240 - 36,969,164 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Tap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,638,257 - 4,652,296 (-)NCBIGRCr8
mRatBN7.2204,636,347 - 4,650,387 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,636,357 - 4,650,407 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,388,631 - 5,403,107 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,750,374 - 4,764,850 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,233,719 - 5,246,401 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,995,544 - 4,009,587 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,198,258 - 5,212,624 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,995,544 - 4,009,587 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,075,031 - 6,089,429 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0207,259,226 - 7,273,268 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,770,446 - 4,784,488 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,770,672 - 4,784,715 (-)NCBI
Celera206,237,501 - 6,251,447 (-)NCBICelera
Cytogenetic Map20p12NCBI
Tap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,477,341 - 1,498,575 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,480,217 - 1,499,032 (-)NCBIChiLan1.0ChiLan1.0
TAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,300,349 - 47,313,984 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,171,904 - 43,185,535 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,394,586 - 32,408,297 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1633,513,321 - 33,523,780 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,507,332 - 33,523,750 (-)Ensemblpanpan1.1panPan2
TAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,407,512 - 2,417,469 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,378,126 - 2,432,303 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,489,442 - 2,499,082 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0122,689,106 - 2,699,061 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl122,652,372 - 2,699,034 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,406,835 - 2,416,483 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,488,331 - 2,497,947 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,562,598 - 2,572,236 (-)NCBIUU_Cfam_GSD_1.0
TAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,045,685 - 25,056,300 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,045,085 - 25,056,915 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,412,165 - 29,423,473 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,266,870 - 39,277,658 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604432,614,899 - 32,625,447 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,827,706 - 23,837,356 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,827,782 - 23,845,690 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005318843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000003418   ⟹   ENSSTOP00000003060
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647625,913,663 - 25,923,427 (+)Ensembl
RefSeq Acc Id: XM_005318843   ⟹   XP_005318900
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494638,036,847 - 38,046,599 (-)NCBI
SpeTri2.0NW_00493647625,913,699 - 25,923,419 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005318900 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000003060.3
GenBank Protein KAG3289187 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005318900   ⟸   XM_005318843
- UniProtKB: I3M293 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000003060   ⟸   ENSSTOT00000003418
Protein Domains
ABC transmembrane type-1   ABC transporter


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003413 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003418.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/TrEMBL
  ABC_Tap-like UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Tap2/ABCB3 UniProtKB/TrEMBL
  Type_1_exporter UniProtKB/TrEMBL
NCBI Gene Tap2 ENTREZGENE
PANTHER ATP BINDING CASSETTE SUBFAMILY B MEMBER 9 UniProtKB/TrEMBL
  ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PIRSF ABC_prm/ATPase_B UniProtKB/TrEMBL
PRINTS TAP2PROTEIN UniProtKB/TrEMBL
PROSITE ABC_TM1F UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90123 UniProtKB/TrEMBL
UniProt I3M293 ENTREZGENE, UniProtKB/TrEMBL