Psap (prosaposin) - Rat Genome Database

Name: Psap
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Psap (prosaposin) Ictidomys tridecemlineatus

Analyze

Symbol:

Psap

Name:

prosaposin

RGD ID:

12712142

Description:

ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); identical protein binding (ortholog); lipid antigen binding (ortholog); INVOLVED IN antigen processing and presentation (ortholog); cellular response to organic substance (ortholog); cellular response to reactive oxygen species (ortholog); ASSOCIATED WITH atypical Gaucher's disease due to saposin C deficiency (ortholog); Atypical Krabbe Disease due to Saposin A Deficiency (ortholog); autosomal recessive nonsyndromic deafness 12 (ortholog); FOUND IN aggresome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC101976627; prosaposin, transcript variant X1; prosaposin, transcript variant X2; prosaposin, transcript variant X3

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PSAP (prosaposin)	NCBI	Ortholog
Mus musculus (house mouse):	Psap (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Psap (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Psap (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PSAP (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PSAP (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PSAP (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PSAP (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Psap (prosaposin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	58,483,085 - 58,516,521 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	6,975,770 - 7,009,136 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	6,975,844 - 7,009,460 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atypical Gaucher's disease due to saposin C deficiency (ISO)

Atypical Krabbe Disease due to Saposin A Deficiency (ISO)

autosomal recessive nonsyndromic deafness 12 (ISO)

combined saposin deficiency (ISO)

focal segmental glomerulosclerosis (ISO)

genetic disease (ISO)

Hearing Loss (ISO)

Krabbe disease (ISO)

late onset Parkinson's disease (ISO)

metachromatic leukodystrophy (ISO)

Metachromatic Leukodystrophy due to Saposin B Deficiency (ISO)

retinitis pigmentosa-deafness syndrome (ISO)

Usher syndrome (ISO)

Usher syndrome type 1 (ISO)

Usher Syndrome Type 1B (ISO)

Usher syndrome type 1D (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (IEA)

antigen processing and presentation (ISO)

cellular response to organic substance (ISO)

cellular response to reactive oxygen species (ISO)

ceramide metabolic process (ISO)

cerebellar Purkinje cell differentiation (ISO)

cochlea development (ISO)

corneocyte development (ISO)

cornified envelope assembly (ISO)

developmental growth (ISO)

epithelial cell differentiation involved in prostate gland development (IEA,ISO)

galactosylceramide catabolic process (ISO)

ganglioside GM1 transport to membrane (IEA)

gene expression (ISO)

glucosylceramide metabolic process (ISO)

glycolipid metabolic process (ISO)

inclusion body assembly (ISO)

intracellular protein transport (ISO)

lipid metabolic process (IEA)

lysosomal protein catabolic process (ISO)

lysosomal transport (IEA)

membrane lipid metabolic process (ISO)

micturition (ISO)

myelination (ISO)

nervous system process (ISO)

neuromuscular process controlling balance (ISO)

NK T cell differentiation (ISO)

positive regulation of MAPK cascade (ISO)

prostate gland growth (IEA,ISO)

protein secretion (ISO)

regulation of lipid metabolic process (IEA,ISO)

regulation of MAPK cascade (ISO)

sensory perception of sound (ISO)

sphingolipid metabolic process (IEA,ISO)

walking behavior (ISO)

Cellular Component

aggresome (ISO)

cytoplasm (IEA)

extracellular region (IEA)

extracellular space (IEA)

intracellular membrane-bounded organelle (IEA)

late endosome (IEA)

lysosome (IEA)

Molecular Function

G protein-coupled receptor binding (ISO)

ganglioside GM1 binding (IEA)

ganglioside GM2 binding (IEA)

ganglioside GM3 binding (IEA)

ganglioside GP1c binding (IEA)

ganglioside GT1b binding (IEA)

identical protein binding (ISO)

lipid antigen binding (ISO)

phospholipid binding (IEA)

protease binding (IEA)

protein binding (ISO)

protein homodimerization activity (IEA)

scaffold protein binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Psap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	58,483,085 - 58,516,521 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	6,975,770 - 7,009,136 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	6,975,844 - 7,009,460 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSAP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	71,816,298 - 71,851,251 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	71,816,298 - 71,851,251 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	73,576,055 - 73,611,008 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	73,246,061 - 73,281,088 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	73,246,063 - 73,281,015	NCBI
Celera	10	66,858,625 - 66,893,657 (-)	NCBI		Celera
Cytogenetic Map	10	q22.1	NCBI
HuRef	10	67,569,822 - 67,604,837 (-)	NCBI		HuRef
CHM1_1	10	73,858,033 - 73,893,009 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	72,687,031 - 72,721,975 (-)	NCBI		T2T-CHM13v2.0

Psap
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	60,113,436 - 60,138,379 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	60,113,449 - 60,138,376 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	60,277,628 - 60,302,600 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	60,277,627 - 60,302,597 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	59,740,376 - 59,765,348 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	59,673,095 - 59,697,957 (+)	NCBI		MGSCv36	mm8
Celera	10	61,374,486 - 61,399,457 (+)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	30.02	NCBI

Psap
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	28,756,951 - 28,783,422 (+)	NCBI		GRCr8
mRatBN7.2	20	28,214,229 - 28,240,501 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	28,214,271 - 28,240,498 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	29,228,797 - 29,255,391 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	28,615,101 - 28,641,697 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	29,357,562 - 29,384,161 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	29,831,302 - 29,856,876 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	29,831,314 - 29,856,875 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	31,629,564 - 31,668,605 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	27,595,048 - 27,621,574 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	27,608,847 - 27,635,374 (+)	NCBI
Celera	20	29,653,298 - 29,678,819 (+)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

Psap
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955437	19,667,252 - 19,683,669 (+)	NCBI	ChiLan1.0	ChiLan1.0

PSAP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	83,966,632 - 84,001,690 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	83,971,953 - 84,007,011 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	68,286,359 - 68,321,349 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	70,810,591 - 70,845,593 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	70,810,881 - 70,828,781 (-)	Ensembl	panpan1.1		panPan2

PSAP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	22,571,095 - 22,603,880 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	22,572,153 - 22,603,848 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	22,708,767 - 22,741,495 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	22,847,636 - 22,880,854 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	22,847,638 - 22,880,795 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	22,753,725 - 22,786,399 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	22,952,336 - 22,985,298 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	23,306,841 - 23,339,591 (-)	NCBI		UU_Cfam_GSD_1.0

PSAP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	74,734,189 - 74,887,763 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	74,734,185 - 74,820,645 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	80,625,273 - 80,660,726 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PSAP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	59,440,327 - 59,474,773 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	59,440,311 - 59,474,986 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	20,084,030 - 20,118,523 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psap
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	5,726,681 - 5,753,575 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	5,725,697 - 5,753,575 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005325935	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005325936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005325937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000007397 ⟹ ENSSTOP00000006610

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936521	6,975,770 - 7,009,136 (+)	Ensembl

RefSeq Acc Id:

XM_005325935 ⟹ XP_005325992

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	58,483,085 - 58,516,521 (+)	NCBI
SpeTri2.0	NW_004936521	6,975,845 - 7,009,460 (+)	NCBI

Sequence:

show sequence

GGGGAGCAGGTTTATATTCGCGCGGTCAGCTGACGCTCTGCATTGCAGACTGCGGAGTCAGGCG
GCGCCATGTACGCGGTCCTGTTCCTGGCCAGCCTCCTGGGCACTGCTCTAGCCGGCCCCGTCCC
AGACCTGAGAAAATGCTCCGGGGGCTCAGCCGTGCTGTGCCAGGACCTCAAGACGGCGGTGGAC
TGCAGGGCTCTGAAGCACTGTCAGCAGACCGTGTGGAGCAAGCCCACAGTGAAATCCCTTCCGT
GTGACATATGCAAACTGGTCATCACCGAGGCTGGCGACGTGCTGAAAAACAATGCCACTGAGGA
GGAGATCCTCACTTACCTGGAGAAGTTGTGCGACTGGCTTCCTAACACGAACCTGTCGGCCAGG
TGCAAGAAGATGGTCGACTCTAACCTCCCCGTCATCCTGGACTTGATTAAAGGGGAAATGAGCC
GTCCAGAGGAGGTGTGCTCGTCCCTCAACCTCTGCGAGTCTCTTCAGAAGCACCTGGCAGAGCT
GAGCCACCAGAAGCAGCTGGAGGCCAACAAGATCCCGGAAATGGACATGACTGAGGTGGTGGCG
CCCTTTATGGCCAACATCCCCCTCCTCCTGTACCCACAGGATGGCCCCCAGAGCAAGCCCCAGC
CAAAGGCCAGTGGAGACGTCTGCCAGGACTGCATGCAGATGGTGACCGACATCCAGACAGCCGT
GAGGACCAATTCCACCTTTGTGGAGGGCTTGGTGGAGCATGCCAAGGAGGAGTGTGACCGCCTG
GGGCCTGGCATGGCTGACATGTGCAAGAACTATATCAGCCAGTACTCTGAAATCGCCATCCAGA
TGATGATGCACATGCAGGATCAGCAACCCAAGGAGATCTGCGCGCTGGTTGGGTTCTGTGACGA
GGTCAAGGAAGTGCCTCTGCAGACCCTGATTCCCGCCAGAGTGGCCTCCGAGAACGTCCTCCCT
GCCCTGGAACTGATGGATCCCCTCGAGGAGGAGCTGATCCTGGCCCATGCTAACATGTTGTGCA
AGGCGTGTCAATTCGTGGTGAAGAAGGTGGCCGACTTGATCAACAACAACAGCACCATGGAAAA
AATCGTCCATGCTTTGGATACGGCGTGCTCGATGCTGCCCAAGTCTGTGTCGACCGTGTGCCAG
GAGGTGGTGGACACATACAGCGGGTACATCTTGTCAGTGCTTGAGGAGGAGCTGAACCCTGAGC
AGGTGTGCAGAGAGCTCCGTCTCTGCTCCTCTGGCAAGGGCCAGCTCGAGATGATCGGCCGAAT
CGGACTGCCTGAGCTGCCCCCGCTGCCCAAGTCGCCTGCGCTGCCCAAGTCGCCTACACTGCCC
GCCCGGGTGACTCCCCTGAAGGACGGTCCCTTCTGTGAGGTGTGCAAGAAGCTGGTCGGCTACT
TGGAGCACAACCTGGAGAAGAACAGCACCAAGCAGGAGATCCTGTCCGCACTCGAGAAGGGCTG
CAGCTTCCTGCCTGAGCCCTACCAGAAGCAGTGTGACGAGTTTGTGACCGAGTATGAGCCCGTG
CTGGTCGAGGTCCTCCTGGAGGTGATAGACCCGTCCTTTGTGTGCTCGAAAATCGGAGCCTGCT
CCTCTGCCCGCAAGCTGCTCTTGGGAGCTGAGAGGTGTGTCTGGGGCCCCAGCTACTGGTGCCG
GAACGCGGAGACGGCAGCCCAGTGTAATGCTGTCGAGCATTGCAAGCGTCACGTATGGAACTAG
GATTCCATCTTGGAGAAGCCGTAGCCTGTTTCCCTCCTTGTGTGTCTGGGGTAACGAACGCACA
GACCTGTCGGTCGTAAGAGCAGGACCCTCCTTTTGACCACCCCGATTTGTCTCCCTTATTGTAG
CATTGCTGTCACGGGGGAGGTGTCTCCCCACCAACATAGCTGCTTCAGTGTCCCCTCTGCTGGG
GGGACACACTGGCCTGAGGTCTTGAGCCACCCTCTCAGCAGGGGCCTTGTTCTGAGCCCTGACA
GGCTTGGGTGCTGGTAGGTTTGTGCTTCTGAGGTCACTTCCTGTCCCCTTTCCTGCTGTACAGA
GCAGCCAGAGGCAGTTCAGAAGAATTGGGTGTTTTAAATAATTCCTATGGGGGCAGTGCAGAGA
CCTTGGAAGCCGCTACTGGTGGCCAGTGGGTGCGGTGGCCCCAGGTTGACCCTTGTTTTTGCTT
TCCTGTCTTTTCCTGGGGATACCTTGTTTAGGGTTCTGTGGGTTTGGGTTGGGAGGGGAAATTT
CACCTGAATGTAACCTGCTGGCTGTACCTGGAGGTCCTGTGCACCGTGGCAACCGCTTGCTCAG
TGTCTGCTGGAGTCCTGCTTCGTGCCTCTGCCCACCCCTGCCCCTGCTGTGGATTTTTTCTTTT
TTTTTTAATTTTCCCTTTCAAATAAATGTGGATAACAGCTCCTAAGTCCCTGCTTGGTAGAGAG
TGGCAGGCAGGGTCTGCTGGGTGTGGAGTGGGTACTATTGTCTGGGCTCGGCCGCTGCCTGTTT
GGCCACCAAAGCTGTTCTACTTCTGGTTGCCAAGAGACAAGCAGAGCAGATGCTATGAAATGAA
CTTAGTGGTTTTCATTTGTTTTGCACTAAAATTTCTGTGATTTAACAATAAAGTTCTGTTAACC
AGA

hide sequence

RefSeq Acc Id:

XM_005325936 ⟹ XP_005325993

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	58,483,085 - 58,516,521 (+)	NCBI
SpeTri2.0	NW_004936521	6,975,844 - 7,009,460 (+)	NCBI

Sequence:

show sequence

CGGGGAGCAGGTTTATATTCGCGCGGTCAGCTGACGCTCTGCATTGCAGACTGCGGAGTCAGGC
GGCGCCATGTACGCGGTCCTGTTCCTGGCCAGCCTCCTGGGCACTGCTCTAGCCGGCCCCGTCC
CAGACCTGAGAAAATGCTCCGGGGGCTCAGCCGTGCTGTGCCAGGACCTCAAGACGGCGGTGGA
CTGCAGGGCTCTGAAGCACTGTCAGCAGACCGTGTGGAGCAAGCCCACAGTGAAATCCCTTCCG
TGTGACATATGCAAACTGGTCATCACCGAGGCTGGCGACGTGCTGAAAAACAATGCCACTGAGG
AGGAGATCCTCACTTACCTGGAGAAGTTGTGCGACTGGCTTCCTAACACGAACCTGTCGGCCAG
GTGCAAGAAGATGGTCGACTCTAACCTCCCCGTCATCCTGGACTTGATTAAAGGGGAAATGAGC
CGTCCAGAGGAGGTGTGCTCGTCCCTCAACCTCTGCGAGTCTCTTCAGAAGCACCTGGCAGAGC
TGAGCCACCAGAAGCAGCTGGAGGCCAACAAGATCCCGGAAATGGACATGACTGAGGTGGTGGC
GCCCTTTATGGCCAACATCCCCCTCCTCCTGTACCCACAGGATGGCCCCCAGAGCAAGCCCCAG
CCAAAGGCCAGTGGAGACGTCTGCCAGGACTGCATGCAGATGGTGACCGACATCCAGACAGCCG
TGAGGACCAATTCCACCTTTGTGGAGGGCTTGGTGGAGCATGCCAAGGAGGAGTGTGACCGCCT
GGGGCCTGGCATGGCTGACATGTGCAAGAACTATATCAGCCAGTACTCTGAAATCGCCATCCAG
ATGATGATGCACATGGATCAGCAACCCAAGGAGATCTGCGCGCTGGTTGGGTTCTGTGACGAGG
TCAAGGAAGTGCCTCTGCAGACCCTGATTCCCGCCAGAGTGGCCTCCGAGAACGTCCTCCCTGC
CCTGGAACTGATGGATCCCCTCGAGGAGGAGCTGATCCTGGCCCATGCTAACATGTTGTGCAAG
GCGTGTCAATTCGTGGTGAAGAAGGTGGCCGACTTGATCAACAACAACAGCACCATGGAAAAAA
TCGTCCATGCTTTGGATACGGCGTGCTCGATGCTGCCCAAGTCTGTGTCGACCGTGTGCCAGGA
GGTGGTGGACACATACAGCGGGTACATCTTGTCAGTGCTTGAGGAGGAGCTGAACCCTGAGCAG
GTGTGCAGAGAGCTCCGTCTCTGCTCCTCTGGCAAGGGCCAGCTCGAGATGATCGGCCGAATCG
GACTGCCTGAGCTGCCCCCGCTGCCCAAGTCGCCTGCGCTGCCCAAGTCGCCTACACTGCCCGC
CCGGGTGACTCCCCTGAAGGACGGTCCCTTCTGTGAGGTGTGCAAGAAGCTGGTCGGCTACTTG
GAGCACAACCTGGAGAAGAACAGCACCAAGCAGGAGATCCTGTCCGCACTCGAGAAGGGCTGCA
GCTTCCTGCCTGAGCCCTACCAGAAGCAGTGTGACGAGTTTGTGACCGAGTATGAGCCCGTGCT
GGTCGAGGTCCTCCTGGAGGTGATAGACCCGTCCTTTGTGTGCTCGAAAATCGGAGCCTGCTCC
TCTGCCCGCAAGCTGCTCTTGGGAGCTGAGAGGTGTGTCTGGGGCCCCAGCTACTGGTGCCGGA
ACGCGGAGACGGCAGCCCAGTGTAATGCTGTCGAGCATTGCAAGCGTCACGTATGGAACTAGGA
TTCCATCTTGGAGAAGCCGTAGCCTGTTTCCCTCCTTGTGTGTCTGGGGTAACGAACGCACAGA
CCTGTCGGTCGTAAGAGCAGGACCCTCCTTTTGACCACCCCGATTTGTCTCCCTTATTGTAGCA
TTGCTGTCACGGGGGAGGTGTCTCCCCACCAACATAGCTGCTTCAGTGTCCCCTCTGCTGGGGG
GACACACTGGCCTGAGGTCTTGAGCCACCCTCTCAGCAGGGGCCTTGTTCTGAGCCCTGACAGG
CTTGGGTGCTGGTAGGTTTGTGCTTCTGAGGTCACTTCCTGTCCCCTTTCCTGCTGTACAGAGC
AGCCAGAGGCAGTTCAGAAGAATTGGGTGTTTTAAATAATTCCTATGGGGGCAGTGCAGAGACC
TTGGAAGCCGCTACTGGTGGCCAGTGGGTGCGGTGGCCCCAGGTTGACCCTTGTTTTTGCTTTC
CTGTCTTTTCCTGGGGATACCTTGTTTAGGGTTCTGTGGGTTTGGGTTGGGAGGGGAAATTTCA
CCTGAATGTAACCTGCTGGCTGTACCTGGAGGTCCTGTGCACCGTGGCAACCGCTTGCTCAGTG
TCTGCTGGAGTCCTGCTTCGTGCCTCTGCCCACCCCTGCCCCTGCTGTGGATTTTTTCTTTTTT
TTTTAATTTTCCCTTTCAAATAAATGTGGATAACAGCTCCTAAGTCCCTGCTTGGTAGAGAGTG
GCAGGCAGGGTCTGCTGGGTGTGGAGTGGGTACTATTGTCTGGGCTCGGCCGCTGCCTGTTTGG
CCACCAAAGCTGTTCTACTTCTGGTTGCCAAGAGACAAGCAGAGCAGATGCTATGAAATGAACT
TAGTGGTTTTCATTTGTTTTGCACTAAAATTTCTGTGATTTAACAATAAAGTTCTGTTAACCAG
A

hide sequence

RefSeq Acc Id:

XM_005325937 ⟹ XP_005325994

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	58,483,085 - 58,516,521 (+)	NCBI
SpeTri2.0	NW_004936521	6,975,844 - 7,009,460 (+)	NCBI

Sequence:

show sequence

CGGGGAGCAGGTTTATATTCGCGCGGTCAGCTGACGCTCTGCATTGCAGACTGCGGAGTCAGGC
GGCGCCATGTACGCGGTCCTGTTCCTGGCCAGCCTCCTGGGCACTGCTCTAGCCGGCCCCGTCC
CAGACCTGAGAAAATGCTCCGGGGGCTCAGCCGTGCTGTGCCAGGACCTCAAGACGGCGGTGGA
CTGCAGGGCTCTGAAGCACTGTCAGCAGACCGTGTGGAGCAAGCCCACAGTGAAATCCCTTCCG
TGTGACATATGCAAACTGGTCATCACCGAGGCTGGCGACGTGCTGAAAAACAATGCCACTGAGG
AGGAGATCCTCACTTACCTGGAGAAGTTGTGCGACTGGCTTCCTAACACGAACCTGTCGGCCAG
GTGCAAGAAGATGGTCGACTCTAACCTCCCCGTCATCCTGGACTTGATTAAAGGGGAAATGAGC
CGTCCAGAGGAGGTGTGCTCGTCCCTCAACCTCTGCGAGTCTCTTCAGAAGCACCTGGCAGAGC
TGAGCCACCAGAAGCAGCTGGAGGCCAACAAGATCCCGGAAATGGACATGACTGAGGTGGTGGC
GCCCTTTATGGCCAACATCCCCCTCCTCCTGTACCCACAGGATGGCCCCCAGAGCAAGCCCCAG
CCAAAGGCCAGTGGAGACGTCTGCCAGGACTGCATGCAGATGGTGACCGACATCCAGACAGCCG
TGAGGACCAATTCCACCTTTGTGGAGGGCTTGGTGGAGCATGCCAAGGAGGAGTGTGACCGCCT
GGGGCCTGGCATGGCTGACATGTGCAAGAACTATATCAGCCAGTACTCTGAAATCGCCATCCAG
ATGATGATGCACATGCAACCCAAGGAGATCTGCGCGCTGGTTGGGTTCTGTGACGAGGTCAAGG
AAGTGCCTCTGCAGACCCTGATTCCCGCCAGAGTGGCCTCCGAGAACGTCCTCCCTGCCCTGGA
ACTGATGGATCCCCTCGAGGAGGAGCTGATCCTGGCCCATGCTAACATGTTGTGCAAGGCGTGT
CAATTCGTGGTGAAGAAGGTGGCCGACTTGATCAACAACAACAGCACCATGGAAAAAATCGTCC
ATGCTTTGGATACGGCGTGCTCGATGCTGCCCAAGTCTGTGTCGACCGTGTGCCAGGAGGTGGT
GGACACATACAGCGGGTACATCTTGTCAGTGCTTGAGGAGGAGCTGAACCCTGAGCAGGTGTGC
AGAGAGCTCCGTCTCTGCTCCTCTGGCAAGGGCCAGCTCGAGATGATCGGCCGAATCGGACTGC
CTGAGCTGCCCCCGCTGCCCAAGTCGCCTGCGCTGCCCAAGTCGCCTACACTGCCCGCCCGGGT
GACTCCCCTGAAGGACGGTCCCTTCTGTGAGGTGTGCAAGAAGCTGGTCGGCTACTTGGAGCAC
AACCTGGAGAAGAACAGCACCAAGCAGGAGATCCTGTCCGCACTCGAGAAGGGCTGCAGCTTCC
TGCCTGAGCCCTACCAGAAGCAGTGTGACGAGTTTGTGACCGAGTATGAGCCCGTGCTGGTCGA
GGTCCTCCTGGAGGTGATAGACCCGTCCTTTGTGTGCTCGAAAATCGGAGCCTGCTCCTCTGCC
CGCAAGCTGCTCTTGGGAGCTGAGAGGTGTGTCTGGGGCCCCAGCTACTGGTGCCGGAACGCGG
AGACGGCAGCCCAGTGTAATGCTGTCGAGCATTGCAAGCGTCACGTATGGAACTAGGATTCCAT
CTTGGAGAAGCCGTAGCCTGTTTCCCTCCTTGTGTGTCTGGGGTAACGAACGCACAGACCTGTC
GGTCGTAAGAGCAGGACCCTCCTTTTGACCACCCCGATTTGTCTCCCTTATTGTAGCATTGCTG
TCACGGGGGAGGTGTCTCCCCACCAACATAGCTGCTTCAGTGTCCCCTCTGCTGGGGGGACACA
CTGGCCTGAGGTCTTGAGCCACCCTCTCAGCAGGGGCCTTGTTCTGAGCCCTGACAGGCTTGGG
TGCTGGTAGGTTTGTGCTTCTGAGGTCACTTCCTGTCCCCTTTCCTGCTGTACAGAGCAGCCAG
AGGCAGTTCAGAAGAATTGGGTGTTTTAAATAATTCCTATGGGGGCAGTGCAGAGACCTTGGAA
GCCGCTACTGGTGGCCAGTGGGTGCGGTGGCCCCAGGTTGACCCTTGTTTTTGCTTTCCTGTCT
TTTCCTGGGGATACCTTGTTTAGGGTTCTGTGGGTTTGGGTTGGGAGGGGAAATTTCACCTGAA
TGTAACCTGCTGGCTGTACCTGGAGGTCCTGTGCACCGTGGCAACCGCTTGCTCAGTGTCTGCT
GGAGTCCTGCTTCGTGCCTCTGCCCACCCCTGCCCCTGCTGTGGATTTTTTCTTTTTTTTTTAA
TTTTCCCTTTCAAATAAATGTGGATAACAGCTCCTAAGTCCCTGCTTGGTAGAGAGTGGCAGGC
AGGGTCTGCTGGGTGTGGAGTGGGTACTATTGTCTGGGCTCGGCCGCTGCCTGTTTGGCCACCA
AAGCTGTTCTACTTCTGGTTGCCAAGAGACAAGCAGAGCAGATGCTATGAAATGAACTTAGTGG
TTTTCATTTGTTTTGCACTAAAATTTCTGTGATTTAACAATAAAGTTCTGTTAACCAGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005325992	(Get FASTA)	NCBI Sequence Viewer
	XP_005325993	(Get FASTA)	NCBI Sequence Viewer
	XP_005325994	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000006610.3
GenBank Protein	KAG3264743	(Get FASTA)	NCBI Sequence Viewer
	KAG3264744	(Get FASTA)	NCBI Sequence Viewer
	KAG3264745	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005325992 ⟸ XM_005325935
- Peptide Label:	isoform X1
- UniProtKB:	I3M9M9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYAVLFLASLLGTALAGPVPDLRKCSGGSAVLCQDLKTAVDCRALKHCQQTVWSKPTVKSLPCD ICKLVITEAGDVLKNNATEEEILTYLEKLCDWLPNTNLSARCKKMVDSNLPVILDLIKGEMSRP EEVCSSLNLCESLQKHLAELSHQKQLEANKIPEMDMTEVVAPFMANIPLLLYPQDGPQSKPQPK ASGDVCQDCMQMVTDIQTAVRTNSTFVEGLVEHAKEECDRLGPGMADMCKNYISQYSEIAIQMM MHMQDQQPKEICALVGFCDEVKEVPLQTLIPARVASENVLPALELMDPLEEELILAHANMLCKA CQFVVKKVADLINNNSTMEKIVHALDTACSMLPKSVSTVCQEVVDTYSGYILSVLEEELNPEQV CRELRLCSSGKGQLEMIGRIGLPELPPLPKSPALPKSPTLPARVTPLKDGPFCEVCKKLVGYLE HNLEKNSTKQEILSALEKGCSFLPEPYQKQCDEFVTEYEPVLVEVLLEVIDPSFVCSKIGACSS ARKLLLGAERCVWGPSYWCRNAETAAQCNAVEHCKRHVWN hide sequence

RefSeq Acc Id:	XP_005325993 ⟸ XM_005325936
- Peptide Label:	isoform X2
- UniProtKB:	I3M9M9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYAVLFLASLLGTALAGPVPDLRKCSGGSAVLCQDLKTAVDCRALKHCQQTVWSKPTVKSLPCD ICKLVITEAGDVLKNNATEEEILTYLEKLCDWLPNTNLSARCKKMVDSNLPVILDLIKGEMSRP EEVCSSLNLCESLQKHLAELSHQKQLEANKIPEMDMTEVVAPFMANIPLLLYPQDGPQSKPQPK ASGDVCQDCMQMVTDIQTAVRTNSTFVEGLVEHAKEECDRLGPGMADMCKNYISQYSEIAIQMM MHMDQQPKEICALVGFCDEVKEVPLQTLIPARVASENVLPALELMDPLEEELILAHANMLCKAC QFVVKKVADLINNNSTMEKIVHALDTACSMLPKSVSTVCQEVVDTYSGYILSVLEEELNPEQVC RELRLCSSGKGQLEMIGRIGLPELPPLPKSPALPKSPTLPARVTPLKDGPFCEVCKKLVGYLEH NLEKNSTKQEILSALEKGCSFLPEPYQKQCDEFVTEYEPVLVEVLLEVIDPSFVCSKIGACSSA RKLLLGAERCVWGPSYWCRNAETAAQCNAVEHCKRHVWN hide sequence

RefSeq Acc Id:	XP_005325994 ⟸ XM_005325937
- Peptide Label:	isoform X3
- UniProtKB:	I3M9M9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYAVLFLASLLGTALAGPVPDLRKCSGGSAVLCQDLKTAVDCRALKHCQQTVWSKPTVKSLPCD ICKLVITEAGDVLKNNATEEEILTYLEKLCDWLPNTNLSARCKKMVDSNLPVILDLIKGEMSRP EEVCSSLNLCESLQKHLAELSHQKQLEANKIPEMDMTEVVAPFMANIPLLLYPQDGPQSKPQPK ASGDVCQDCMQMVTDIQTAVRTNSTFVEGLVEHAKEECDRLGPGMADMCKNYISQYSEIAIQMM MHMQPKEICALVGFCDEVKEVPLQTLIPARVASENVLPALELMDPLEEELILAHANMLCKACQF VVKKVADLINNNSTMEKIVHALDTACSMLPKSVSTVCQEVVDTYSGYILSVLEEELNPEQVCRE LRLCSSGKGQLEMIGRIGLPELPPLPKSPALPKSPTLPARVTPLKDGPFCEVCKKLVGYLEHNL EKNSTKQEILSALEKGCSFLPEPYQKQCDEFVTEYEPVLVEVLLEVIDPSFVCSKIGACSSARK LLLGAERCVWGPSYWCRNAETAAQCNAVEHCKRHVWN hide sequence

RefSeq Acc Id:

ENSSTOP00000006610 ⟸ ENSSTOT00000007397

Protein Domains

Saposin A-type Saposin B-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000007400	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000007397.3	UniProtKB/TrEMBL
Gene3D-CATH	Saposin-like	UniProtKB/TrEMBL
InterPro	SAP_A	UniProtKB/TrEMBL
	SapB_1	UniProtKB/TrEMBL
	SapB_2	UniProtKB/TrEMBL
	Saposin	UniProtKB/TrEMBL
	Saposin-like	UniProtKB/TrEMBL
	Saposin_chordata	UniProtKB/TrEMBL
	SaposinB_dom	UniProtKB/TrEMBL
NCBI Gene	Psap	ENTREZGENE
PANTHER	PROSAPOSIN	UniProtKB/TrEMBL
	SAPOSIN-RELATED	UniProtKB/TrEMBL
Pfam	SapA	UniProtKB/TrEMBL
	SapB_1	UniProtKB/TrEMBL
	SapB_2	UniProtKB/TrEMBL
PIRSF	Saposin	UniProtKB/TrEMBL
PRINTS	SAPOSIN	UniProtKB/TrEMBL
PROSITE	SAP_A	UniProtKB/TrEMBL
	SAP_B	UniProtKB/TrEMBL
SMART	SAPA	UniProtKB/TrEMBL
	SapB	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47862	UniProtKB/TrEMBL
UniProt	I3M9M9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-08-09	Psap	prosaposin	LOC101976627	prosaposin	Symbol and/or name change	5135510	APPROVED
2021-03-26	LOC101976627	prosaposin	Psap	prosaposin	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM