Acvrl1 (activin A receptor like type 1)

Gene: Acvrl1 (activin A receptor like type 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Acvrl1

Name:

activin A receptor like type 1

RGD ID:

12708623

Description:

ENCODES a protein that exhibits activin binding (inferred); activin receptor activity, type I (inferred); ATP binding (inferred); INVOLVED IN angiogenesis (ortholog); blood vessel morphogenesis (ortholog); BMP signaling pathway (ortholog); PARTICIPATES IN activin signaling pathway; ASSOCIATED WITH arteriovenous malformation (ortholog); arteriovenous malformations of the brain (ortholog); Cognitive Impairment with or Without Cerebellar Ataxia (ortholog); FOUND IN cell surface (ortholog); dendrite (ortholog); neuronal cell body (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serine/threonine-protein kinase receptor R3

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	63,786,735 - 63,800,651 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	9,364,149 - 9,379,431 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	9,364,551 - 9,379,131 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

arteriovenous malformation (ISO)

arteriovenous malformations of the brain (ISO)

Cognitive Impairment with or Without Cerebellar Ataxia (ISO)

COVID-19 (ISO)

Epistaxis (ISO)

genetic disease (ISO)

hemorrhagic disease (ISO)

hereditary hemorrhagic telangiectasia (ISO)

Hereditary Hemorrhagic Telangiectasia, Type 1 (ISO)

Hereditary Hemorrhagic Telangiectasia, Type 2 (ISO)

Leber congenital amaurosis (ISO)

Primary Pulmonary Hypertension, 1 (ISO)

Pulmonary Arterial Hypertension (ISO)

Pulmonary Arterial Hypertension, Hereditary Hemorrhagic Telangiectasia-Related (ISO)

pulmonary hypertension (ISO)

thrombocytopenia (ISO)

transient cerebral ischemia (ISO)

Vascular Remodeling (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activin receptor signaling pathway (IEA)

angiogenesis (IEA,ISO)

artery development (IEA)

blood circulation (IEA)

blood vessel morphogenesis (IEA,ISO)

blood vessel remodeling (IEA)

BMP signaling pathway (IEA,ISO)

cell surface receptor protein serine/threonine kinase signaling pathway (IEA)

cellular response to BMP stimulus (IEA)

cellular response to transforming growth factor beta stimulus (IEA)

dorsal aorta morphogenesis (IEA)

endocardial cushion morphogenesis (IEA)

endocardial cushion to mesenchymal transition (ISO)

endothelial tube morphogenesis (IEA)

heart development (IEA)

in utero embryonic development (IEA,ISO)

lymphangiogenesis (IEA)

lymphatic endothelial cell differentiation (IEA)

negative regulation of blood vessel endothelial cell migration (IEA)

negative regulation of cell adhesion (IEA)

negative regulation of cell growth (IEA)

negative regulation of cell migration (IEA)

negative regulation of cell population proliferation (IEA)

negative regulation of endothelial cell differentiation (IEA)

negative regulation of endothelial cell migration (IEA)

negative regulation of endothelial cell proliferation (IEA)

negative regulation of focal adhesion assembly (IEA)

negative regulation of gene expression (IEA)

positive regulation of angiogenesis (IEA,ISO)

positive regulation of bicellular tight junction assembly (IEA)

positive regulation of BMP signaling pathway (IEA)

positive regulation of DNA-templated transcription (IEA)

positive regulation of endothelial cell differentiation (IEA)

positive regulation of endothelial cell proliferation (IEA)

positive regulation of epithelial cell differentiation (IEA,ISO)

positive regulation of Notch signaling pathway (IEA,ISO)

positive regulation of SMAD protein signal transduction (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

regulation of blood pressure (IEA)

regulation of DNA-templated transcription (IEA)

response to hypoxia (ISO)

retina vasculature development in camera-type eye (IEA)

signal transduction (IEA)

transforming growth factor beta receptor signaling pathway (IEA,ISO)

venous blood vessel development (IEA)

wound healing, spreading of epidermal cells (IEA)

Cellular Component

BMP receptor complex (IEA)

cell surface (IEA,ISO)

dendrite (ISO)

membrane (IEA)

neuronal cell body (ISO)

plasma membrane (IEA)

Molecular Function

activin binding (IEA)

activin receptor activity, type I (IEA)

ATP binding (IEA)

BMP receptor activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein kinase binding (IEA)

protein serine/threonine kinase activity (IEA)

SMAD binding (IEA)

transforming growth factor beta binding (IEA)

transforming growth factor beta receptor activity (IEA)

transforming growth factor beta receptor activity, type I (IEA)

transmembrane receptor protein serine/threonine kinase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

activin signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Acvrl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	63,786,735 - 63,800,651 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	9,364,149 - 9,379,431 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	9,364,551 - 9,379,131 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACVRL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	51,906,944 - 51,923,361 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	51,906,908 - 51,923,361 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	52,301,288 - 52,317,145 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	50,587,469 - 50,603,412 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	50,587,468 - 50,601,120	NCBI
Celera	12	51,103,338 - 51,119,286 (+)	NCBI		Celera
Cytogenetic Map	12	q13.13	ENTREZGENE
HuRef	12	49,334,280 - 49,350,228 (+)	NCBI		HuRef
CHM1_1	12	52,267,590 - 52,283,516 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	51,870,516 - 51,886,934 (+)	NCBI		T2T-CHM13v2.0

Acvrl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	101,026,403 - 101,043,217 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	101,026,403 - 101,043,217 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	101,128,522 - 101,145,336 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	101,128,522 - 101,145,336 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	100,958,968 - 100,975,767 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	100,956,556 - 100,986,456 (+)	NCBI		MGSCv36	mm8
Celera	15	103,276,934 - 103,293,737 (+)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	56.41	NCBI

Acvrl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	134,117,917 - 134,135,306 (+)	NCBI		GRCr8
mRatBN7.2	7	132,239,200 - 132,256,592 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	132,239,729 - 132,256,591 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	134,047,098 - 134,058,156 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	136,276,614 - 136,287,668 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	136,187,385 - 136,198,468 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	142,769,942 - 142,787,336 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	142,776,252 - 142,787,335 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	140,571,236 - 140,588,083 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	139,873,596 - 139,884,675 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	139,944,251 - 139,961,111 (+)	NCBI
Celera	7	128,712,554 - 128,723,633 (+)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

Acvrl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955547	2,279,042 - 2,294,443 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955547	2,278,548 - 2,293,865 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACVRL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	42,272,321 - 42,288,400 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	42,269,084 - 42,282,021 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	36,839,869 - 36,856,351 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	37,615,888 - 37,631,691 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	37,615,888 - 37,631,691 (-)	Ensembl	panpan1.1		panPan2

ACVRL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	3,075,373 - 3,090,549 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	3,076,124 - 3,092,469 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	43,166,746 - 43,181,176 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	3,072,148 - 3,086,549 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	3,072,149 - 3,081,623 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	3,088,717 - 3,103,128 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	3,075,021 - 3,089,444 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	43,565,141 - 43,579,587 (+)	NCBI		UU_Cfam_GSD_1.0

ACVRL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	17,268,130 - 17,286,276 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	17,267,483 - 17,284,155 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	17,850,783 - 17,871,395 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACVRL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	48,063,099 - 48,091,705 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	48,082,135 - 48,093,630 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	197,998,886 - 198,027,294 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acvrl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624816	404,358 - 426,217 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624816	402,412 - 426,217 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005324974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040280618	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040280619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000000475 ⟹ ENSSTOP00000000427

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936512	9,364,149 - 9,379,431 (+)	Ensembl

RefSeq Acc Id:

XM_005324974 ⟹ XP_005325031

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	63,786,735 - 63,800,651 (-)	NCBI
SpeTri2.0	NW_004936512	9,364,551 - 9,379,131 (+)	NCBI

Sequence:

show sequence

CTGGGCGGGGGCTCTAGCCCGTGACCCGGAGCTGGGGGTGGCCGGGACCGCGGCCGCGCTGGGG
TCTGGGAGCCGCGCGGGGGAGCGGCTGGTCCCGGGGCTCGGCTGGGGTCGAGCGGGCGGCCGGT
CGGCGAGCTGGGCAATAGGAAACGGTTTATTAGGAGGGAGTGGTGGAGCCGGGCCAGGCAGGAA
GACGCTGGAATAAGAAACATTTTTGCTCCAGCCCCCTTTCCAGTCCCGGGAGGCCGCCGCGCCA
GCCGCGCCGAGCGAACCCCTGCCCGGCCCCAGCACGTCCGGGGCTGCGCCCGGACCCCGGGACC
CGGGTCCCCACTCCAGTGCTTGCCGTGTATCGGCGGCCGCCACCGGGGAGAGGAGGCGGCCCCC
GCCCGCTCACGCTCGCGTGGTGCCGGCTGGCCCGAAGGGACCATGACCTTGGGCCCCCCCAGAA
GGGGCTTTCTGATGCTGCTGATGGCTTTAGGCCTAACCCAGGGTGACCCTGTGAAGCCCTCTCG
GGGCCCGCTGGTGACCTGCACATGCAAGAACCCACACTGCAGGGGGCCTACCTGCGAGGGGGCC
TGGTGCACAGTAGTGCTGGTCCGTGAGCAGGGCAGGCACCCCCAGGAACATCGAGGCTGTGGGA
ACCTGCACCAGGAGCTCTGCAGGGGACGCCCCACTGACTTTGTCAATCATTACTGCTGCTTCAG
CCCCTTCTGTAACCGCAATGTGTCCCTGGTGCTGAATGCCACTAAACCTCCTCCGGAGCAGCCT
GGAATAGATGGTCAGCTTCCTCTGATCCTGGGCCCCGTGCTGGCCTTGCTGGTCCTGGTGGCCT
TGGGTGCTCTGGGCCTGTGGCATATCCGGCAGAGGCAAGAGAAACAGCGGGGCCTGCACAGCGA
CCTGGGCGAGTCCAGTCTCATCCTGAAGGCATCCGAGCAGGGAGATAGCATGTTGGGGGACTTC
TTGGACAGTGACTGTACTACCGGCAGTGGCTCTGGGCTCCCCTTTCTGGTGCAGAGGACCGTGG
CACGACAGGTTGCCCTGGTGGAGTGTGTGGGAAAGGGACGCTATGGTGAGGTGTGGCGAGGCTT
GTGGCATGGTGAGAGCGTCGCGGTCAAGATTTTCTCCTCAAGGGATGAACAGTCCTGGTTTCGG
GAGACAGAAATCTACAACACTGTGTTGCTCAGACACGACAACATCCTAGGCTTCATCGCCTCGG
ACATGACTTCCCGCAATTCAAGCACGCAGCTGTGGCTCATCACGCACTACCATGAGCACGGCTC
CCTCTATGACTTTCTGCAGAGGCAAACGCTTGAGCCCCAGCTGGCCCTGAAGTTAGCTGTGTCC
GCGGCCTGCGGCCTGGCGCACCTGCATGTGGAAATCTTTGGCACGCAGGGTAAACCGGCCATCG
CCCACCGTGACCTCAAGAGTCGCAACGTGCTGGTCAAGAGCAACTTGCAATGCTGCATTGCCGA
CCTGGGCCTGGCTGTGATGCATTCCCAGGGCAGCGACTACCTGGACATCGGCAATAACCCAAGA
GTGGGCACCAAGCGGTACATGGCACCCGAGGTGCTGGATGAGCAGATCCGCACTGACTGCTTCG
AGTCCTACAAGTGGACTGACATCTGGGCCTTTGGTCTAGTGCTGTGGGAAATTGCTCGACGAAC
CATTGTCAATGGCATTGTGGAGGACTACAGGCCACCCTTCTATGATGTGGTGCCCAATGACCCC
AGCTTTGAAGACATGAAGAAGGTGGTGTGTGTTGATCAGCAAACCCCCACCATCCCCAACCGGC
TGGCTGCAGACCCGGTCCTCTCGGGCCTGGCTCAGATGATGCGGGAGTGCTGGTACCCCACGCC
CTCCGCCCGCCTCACCGCGCTGCGCATCAAGAAGACACTACAGAAACTCAGCCATGGTCCAGAG
AAGCCCAAAGTGATTCACTAACCCAGGGTCGCTGGACTCGCTCTGCCTGCAGTGTGGGGTGGCA
GGGGATTGTGGCCCATCTGGGCAGAGGTAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG
TTTGCGTGCGTGTGTGCATGCGCTGGGGAGGGGTGCCCCCCTCTAGGGCAGCTGTGCCTTCCCA
GCTTGGCCCCTAGCCCATCCAGTCAAAAATACAGCTGGGCTGAAATCTGATCCCGCGCCGTCTG
GCCTGCTCAAAGTGGCCGGCTCCCTGACGCCTGGCTCTCTCCCCATCCCACCCCCCATGCCAGG
AGGGTGTACCCCCTACCACTCCCAGGGCAGGGATGCAAAAGAGGACAGCCTCGCCAGGGAATCC
CAGTCCCGGGCCCAGAGCCTGGGCCTATATTTCCCCTGCCCTTGATCAACCTCACTGCCCCACC
AGAGCTGCCAGGGTGGCACAGGGCCCTGTCCAGCCTTCAGCAGATGCTCTACCCCGCCAGGCCT
CAGCCTGTGACACAAATTCCAAATACCCAGGTTCCTCAGTTGCCCTCTATGGGTTTATATCGCA
ATAGCATGACACCTTGGACTTTATGTCTCACCCACAAGGCCCCAGCTAGCTGAATACCAGCTGT
CTGGAGGAGCTGGGCTGATCCTGCCACTCCGTGACCCCTAGCTATCCTAGCTGACTTGTTAGGG
CATTAAAATTCAAGGGGTCCTGCTGAGGTGTGACAGGAGCATATGGAAGTGGAGAGGTGTCAGG
TCAGATGGGTAAGGCCCAGGACTTAGGATAATTGAGAGGATGTTGAGCTATGTGTGGCAGGGGG
TGGGAAGGAAGGTTCCAGTGGGAGTCCAGAGACCCAAGTTGGGTCCTAGGTACTTGCTCCATGT
CACCAGATTGGACCTTTACTGCCTTAGGACGTTTGTTTCTTCATCAATATACTGAAAGATTTGG
TCCTGATGTCCTTTGAGGTTTCTTTAGCTCTGATTTTCTTTTAATGTCAGCCTAGGGCTGGGGA
TGTGGCTCAAGCGGTAGCGCGCTCGCCTGGCAT

hide sequence

RefSeq Acc Id:

XM_040280618 ⟹ XP_040136552

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	63,786,735 - 63,800,635 (-)	NCBI

RefSeq Acc Id:

XM_040280619 ⟹ XP_040136553

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	63,786,735 - 63,800,600 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005325031	(Get FASTA)	NCBI Sequence Viewer
	XP_040136552	(Get FASTA)	NCBI Sequence Viewer
	XP_040136553	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000000427.3
GenBank Protein	KAG3291929	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005325031 ⟸ XM_005324974

- UniProtKB:

I3LWQ1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTLGPPRRGFLMLLMALGLTQGDPVKPSRGPLVTCTCKNPHCRGPTCEGAWCTVVLVREQGRHP
QEHRGCGNLHQELCRGRPTDFVNHYCCFSPFCNRNVSLVLNATKPPPEQPGIDGQLPLILGPVL
ALLVLVALGALGLWHIRQRQEKQRGLHSDLGESSLILKASEQGDSMLGDFLDSDCTTGSGSGLP
FLVQRTVARQVALVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDN
ILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPQLALKLAVSAACGLAHLHVEIFG
TQGKPAIAHRDLKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDE
QIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCVDQQ
TPTIPNRLAADPVLSGLAQMMRECWYPTPSARLTALRIKKTLQKLSHGPEKPKVIH

hide sequence

RefSeq Acc Id:	XP_040136552 ⟸ XM_040280618
- UniProtKB:	I3LWQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040136553 ⟸ XM_040280619
- UniProtKB:	I3LWQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000000427 ⟸ ENSSTOT00000000475

Protein Domains

GS Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000000477	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000000475.3	UniProtKB/TrEMBL
Gene3D-CATH	2.10.60.10	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	GS_dom	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
	Snake_toxin-like_sf	UniProtKB/TrEMBL
	TGFB_receptor	UniProtKB/TrEMBL
NCBI Gene	Acvrl1	ENTREZGENE
PANTHER	PTHR23255	UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN KINASE RECEPTOR R3	UniProtKB/TrEMBL
Pfam	PK_Tyr_Ser-Thr	UniProtKB/TrEMBL
	TGF_beta_GS	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
	PS51256	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
	SM00467	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
	SSF57302	UniProtKB/TrEMBL
UniProt	I3LWQ1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)