Amn (amnion associated transmembrane protein)

Gene: Amn (amnion associated transmembrane protein) Ictidomys tridecemlineatus

Analyze

Symbol:

Amn

Name:

amnion associated transmembrane protein

RGD ID:

12697371

Description:

ENCODES a protein that exhibits cargo receptor activity (inferred); signaling receptor binding (inferred); INVOLVED IN protein localization (ortholog); renal protein absorption (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); Charcot-Marie-Tooth disease axonal type 2O (ortholog); Edema (ortholog); FOUND IN apical plasma membrane (ortholog); brush border membrane (ortholog); endocytic vesicle (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	3,225,612 - 3,234,832 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936835	961,826 - 970,234 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936835	961,840 - 970,287 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney failure (ISO)

Charcot-Marie-Tooth disease axonal type 2O (ISO)

Edema (ISO)

Extravasation of Diagnostic and Therapeutic Materials (ISO)

genetic disease (ISO)

Herpes Simplex Encephalitis 3 (ISO)

Imerslund-Grasbeck Syndrome (ISO)

Imerslund-Grasbeck Syndrome 1 (ISO)

Imerslund-Grasbeck Syndrome 2 (ISO)

megaloblastic anemia (ISO)

mitochondrial complex IV deficiency nuclear type 17 (ISO)

Neurogenic Inflammation (ISO)

vitamin B12 deficiency (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cobalamin metabolic process (IEA)

cobalamin transport (IEA)

Golgi to plasma membrane protein transport (IEA)

protein localization (IEA,ISO)

protein transport (IEA)

receptor-mediated endocytosis (IEA)

renal protein absorption (IEA,ISO)

Cellular Component

apical part of cell (IEA)

apical plasma membrane (IEA,ISO)

brush border membrane (ISO)

endocytic vesicle (IEA,ISO)

extracellular space (IEA)

membrane (IEA)

microvillus membrane (IEA,ISO)

plasma membrane (IEA)

protein-containing complex (ISO)

receptor complex (IEA,ISO)

Molecular Function

cargo receptor activity (IEA)

protein binding (ISO)

signaling receptor binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Amn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	3,225,612 - 3,234,832 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936835	961,826 - 970,234 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936835	961,840 - 970,287 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AMN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	102,922,663 - 102,930,842 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	102,922,663 - 102,933,596 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	103,389,000 - 103,397,179 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	102,458,747 - 102,467,282 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	102,458,756 - 102,467,282	NCBI
Celera	14	83,443,115 - 83,451,301 (+)	NCBI		Celera
Cytogenetic Map	14	q32.32	NCBI
HuRef	14	83,564,008 - 83,572,214 (+)	NCBI		HuRef
CHM1_1	14	103,326,435 - 103,334,619 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	97,158,908 - 97,167,087 (+)	NCBI		T2T-CHM13v2.0

Amn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	111,237,530 - 111,242,860 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	111,237,529 - 111,242,860 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	111,271,096 - 111,276,426 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	111,271,095 - 111,276,426 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	112,509,322 - 112,514,637 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	111,718,919 - 111,724,234 (+)	NCBI		MGSCv36	mm8
Celera	12	112,465,414 - 112,470,727 (+)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	60.94	NCBI

Amn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	136,132,567 - 136,140,008 (+)	NCBI		GRCr8
mRatBN7.2	6	130,311,372 - 130,318,815 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	130,311,372 - 130,318,815 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	130,482,175 - 130,489,610 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	130,778,168 - 130,785,603 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	130,141,430 - 130,148,872 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	135,724,455 - 135,731,896 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	135,724,455 - 135,731,896 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	144,682,579 - 144,690,020 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	136,031,478 - 136,038,919 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	136,035,629 - 136,044,796 (+)	NCBI
Celera	6	127,868,669 - 127,876,110 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

Amn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955538	2,017,476 - 2,021,890 (+)	NCBI	ChiLan1.0	ChiLan1.0

AMN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	104,076,211 - 104,083,152 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	103,292,709 - 103,299,650 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	83,541,891 - 83,550,346 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	103,356,523 - 103,364,163 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	103,356,773 - 103,365,352 (+)	Ensembl	panpan1.1		panPan2

AMN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	70,800,435 - 70,807,835 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	70,312,298 - 70,320,278 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	71,077,067 - 71,085,111 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	71,077,060 - 71,088,041 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	70,740,802 - 70,748,789 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	70,805,229 - 70,813,173 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	71,205,503 - 71,213,499 (+)	NCBI		UU_Cfam_GSD_1.0

AMN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	7	128,896,585 - 128,904,655 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AMN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	80,884,149 - 80,895,977 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	80,883,911 - 80,893,066 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	68,081,278 - 68,085,885 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Amn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	1,720,216 - 1,725,045 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	1,720,119 - 1,725,042 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005341008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000022131 ⟹ ENSSTOP00000023692

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936835	961,826 - 970,234 (+)	Ensembl

RefSeq Acc Id:

XM_005341008 ⟹ XP_005341065

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	3,225,612 - 3,234,832 (-)	NCBI
SpeTri2.0	NW_004936835	961,840 - 970,287 (+)	NCBI

Sequence:

show sequence

ATGGGCGCGCTGGGACGGCTCCTGCTGGGGCTGCAGCTGTGCGCGCTGACCCGGGCCGCCTACA
AATTCTGGGTCCCCAACACCGGCTTCGATACCGCCACCAACTGGAACCAGAACCGGACACCGTG
CGCCGGAGGCGCTGTCCAGTTCCCTGCAGACAAGATGGTGTCAATCCTGGTGCAAGAAAGTCAC
ACCGTCTCGGATATGCTGCTGCCGCTGGACGGGGAACTCGTGCTGGCCTCGGGAGCGGGATTCA
GCGCGGCAGCCCGGGGCTCGGACCCGGACTGTGGCTCAGACCCCCCGGCGCTCTTCCGCAACCC
CGACCGCTTCTCCTGGGTCGACCCACGCCTGTGGCGCTCGGAGGAGGCGCGCGGCTTCTTCTCC
GTGGACGCCGAGCGCGTGCCCTGCAGTCACGACGACGTCGTCTTCCCGCCCGACGGCTCCTTTC
GCGTGGGGCTCGGCCTCGGCGCCGGCCCCGTGCGCGTCCGCAGCATCTCGGCTCTGGGCCAGAC
GTTCACGCGCGACGAGGACCTGGCCGCTTTCTTGGCGTCGCGATCGGGCCGCCTGCACTTCCAC
GGACCAGGCGCGCTGAGCCTGGGCTCCGAGGCCTGCGCCGACCCGTCGGGCTGCGTGTGCGGCA
CCGCCGAGGCTCTGCCCTGGGTCTGCGCGGCGCTCCTGCAGCCCCTGGGCGGCCGCTGCCCCCA
GGCCTCCTGCCACGACGCCCTCCGGCCTGAGGGGCAGTGCTGCGACCTCTGCGGAGCCATCGTG
TCGTTGACGCACAGCTCCGCATTTGATCTGCAGCGGTACCGGGCGCGGCTGCTGGATGCCTTCC
TGTCACTGCCCCAGTACCAAGGGCTGCAAGTGGCGGTGTCCAGGGTGCCGCGCTGGTCCCGGCT
GCGGGAGGCCGACACCGAGATCCAGGTGGTGCTGGCGGACACTGGACCCGAGACCGGCGGCGCG
GGGCGGCTGGCCCGGGCCCTCGTGGCGGACGTGGCGGAGCAAGGCGAGGCCCTCGGGGTCCTAT
CGGCCGTCCTGCGGGAGTCGGGCGCGCCAGTCGGGGGCGACTCCACGGCCGAGCAGAACGCGCC
CGGGTCCCGCGCGGGGCTCGCAGGCGGCGTGGTGGCCGCGGTGCTGCCGGTGCTGTTGGCGCTG
CTGGGGATCGTGCTGCTGCGCCGCACCGGGAGGCTCAGGTGGAGGAGGCAGGAGGAGGCAGAGC
CCGCCCCTGCGGGGACGCCCTCGGGCTTCAGCAACCCGGTATTCTTCGTGGCGACCTCGGAGGA
GCCGCCCCCAGTGCGGCCTTGCAGTCCCGCCCTGAAGTTGGACAGCAGCACAAGCCACAGCTAC
TTTGACAACCCGCTCTTCGCTGGCGAGGCTGAGGCCTGACCACTGCTGGCGCCCACCTCCTACC
CTGTTGCCCCCTCCTGTGGGGGTGCTGGGTCTCTGACTTGCGGCCTCCTCATCCCTGAGACCTT
AGTTCTTTTCCTGTCTTCTTTGAAGGCCAAGGATAGGCTGGTCTTGCCCAATAAAGGGTTTTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005341065	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000023692.1
GenBank Protein	KAG3260309	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005341065 ⟸ XM_005341008

- UniProtKB:

I3NH45 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGALGRLLLGLQLCALTRAAYKFWVPNTGFDTATNWNQNRTPCAGGAVQFPADKMVSILVQESH
TVSDMLLPLDGELVLASGAGFSAAARGSDPDCGSDPPALFRNPDRFSWVDPRLWRSEEARGFFS
VDAERVPCSHDDVVFPPDGSFRVGLGLGAGPVRVRSISALGQTFTRDEDLAAFLASRSGRLHFH
GPGALSLGSEACADPSGCVCGTAEALPWVCAALLQPLGGRCPQASCHDALRPEGQCCDLCGAIV
SLTHSSAFDLQRYRARLLDAFLSLPQYQGLQVAVSRVPRWSRLREADTEIQVVLADTGPETGGA
GRLARALVADVAEQGEALGVLSAVLRESGAPVGGDSTAEQNAPGSRAGLAGGVVAAVLPVLLAL
LGIVLLRRTGRLRWRRQEEAEPAPAGTPSGFSNPVFFVATSEEPPPVRPCSPALKLDSSTSHSY
FDNPLFAGEAEA

hide sequence

RefSeq Acc Id:

ENSSTOP00000023692 ⟸ ENSSTOT00000022131

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000021673	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000022131.2	UniProtKB/TrEMBL
InterPro	AMN	UniProtKB/TrEMBL
NCBI Gene	Amn	ENTREZGENE
PANTHER	PROTEIN AMNIONLESS	UniProtKB/TrEMBL
	PTHR14995	UniProtKB/TrEMBL
Pfam	Amnionless	UniProtKB/TrEMBL
UniProt	I3NH45	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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