Casp10 (caspase 10) - Rat Genome Database

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Gene: Casp10 (caspase 10) Ictidomys tridecemlineatus
Analyze
Symbol: Casp10
Name: caspase 10
RGD ID: 12690957
Description: ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); cysteine-type endopeptidase activity involved in apoptotic process (inferred); cysteine-type endopeptidase activity involved in apoptotic signaling pathway (inferred); INVOLVED IN apoptotic process (inferred); apoptotic signaling pathway (inferred); positive regulation of canonical NF-kappaB signal transduction (inferred); PARTICIPATES IN extrinsic apoptotic pathway; FasL mediated signaling pathway; Trail mediated signaling pathway; ASSOCIATED WITH autoimmune lymphoproliferative syndrome (ortholog); autoimmune lymphoproliferative syndrome type 2A (ortholog); autoimmune lymphoproliferative syndrome type 2B (ortholog); FOUND IN CD95 death-inducing signaling complex (inferred); ripoptosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: caspase-10
RGD Orthologs
Human
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303158,452,973 - 158,519,327 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936726460,518 - 485,624 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936726460,556 - 489,550 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Casp10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303158,452,973 - 158,519,327 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936726460,518 - 485,624 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936726460,556 - 489,550 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASP10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382201,183,141 - 201,229,406 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2201,182,872 - 201,229,428 (+)EnsemblGRCh38hg38GRCh38
GRCh372202,047,864 - 202,094,129 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362201,755,866 - 201,802,355 (+)NCBINCBI36Build 36hg18NCBI36
Build 342201,873,360 - 201,910,373NCBI
Celera2195,802,231 - 195,848,720 (+)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2193,898,993 - 193,945,498 (+)NCBIHuRef
CHM1_12202,053,600 - 202,100,108 (+)NCBICHM1_1
T2T-CHM13v2.02201,666,595 - 201,712,862 (+)NCBIT2T-CHM13v2.0
CASP10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213103,807,692 - 103,847,091 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B103,822,691 - 103,864,809 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B88,440,199 - 88,479,277 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B206,595,776 - 206,641,775 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B206,595,776 - 206,641,775 (+)Ensemblpanpan1.1panPan2
CASP10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13710,315,867 - 10,350,585 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3711,199,902 - 11,234,408 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03710,220,396 - 10,255,104 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3710,220,511 - 10,254,972 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13710,201,728 - 10,236,190 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03710,180,515 - 10,215,139 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03710,173,823 - 10,208,321 (+)NCBIUU_Cfam_GSD_1.0
CASP10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15104,858,100 - 104,894,933 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115104,858,082 - 104,895,941 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215116,127,433 - 116,215,682 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CASP10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11086,830,101 - 86,884,729 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1086,830,589 - 86,871,200 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040112,551,369 - 112,589,618 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casp10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462488931,132 - 63,774 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000023089   ⟹   ENSSTOP00000021797
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936726460,518 - 485,624 (+)Ensembl
RefSeq Acc Id: XM_040294697   ⟹   XP_040150631
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303158,452,973 - 158,519,327 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040150631 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000021797.2
GenBank Protein KAG3274977 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040150631   ⟸   XM_040294697
- UniProtKB: I3NBQ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000021797   ⟸   ENSSTOT00000023089
Protein Domains
Caspase family p10   Caspase family p20   DED


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002364 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023089.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  3.40.50.1460 UniProtKB/TrEMBL
InterPro Caspase-like_dom_sf UniProtKB/TrEMBL
  Caspase_cys_AS UniProtKB/TrEMBL
  Caspase_his_AS UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/TrEMBL
  DED_dom UniProtKB/TrEMBL
  Pept_C14_caspase UniProtKB/TrEMBL
  Pept_C14_p10 UniProtKB/TrEMBL
  Pept_C14_p20 UniProtKB/TrEMBL
  Pept_C14A UniProtKB/TrEMBL
NCBI Gene Casp10 ENTREZGENE
PANTHER CASPASE 10 UniProtKB/TrEMBL
  DED DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam DED UniProtKB/TrEMBL
  Peptidase_C14 UniProtKB/TrEMBL
PRINTS IL1BCENZYME UniProtKB/TrEMBL
PROSITE CASPASE_CYS UniProtKB/TrEMBL
  CASPASE_HIS UniProtKB/TrEMBL
  CASPASE_P10 UniProtKB/TrEMBL
  CASPASE_P20 UniProtKB/TrEMBL
  DED UniProtKB/TrEMBL
SMART CASc UniProtKB/TrEMBL
  DED UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
  SSF52129 UniProtKB/TrEMBL
UniProt I3NBQ0 ENTREZGENE, UniProtKB/TrEMBL