Akap13 (A-kinase anchoring protein 13) - Rat Genome Database

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Gene: Akap13 (A-kinase anchoring protein 13) Ictidomys tridecemlineatus
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Symbol: Akap13
Name: A-kinase anchoring protein 13
RGD ID: 12687315
Description: ENCODES a protein that exhibits molecular adaptor activity (ortholog); protein kinase A binding (ortholog); small GTPase binding (ortholog); INVOLVED IN adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process (ortholog); bone development (ortholog); cardiac muscle cell differentiation (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Esophageal Neoplasms (ortholog); FOUND IN actin filament (ortholog); cell cortex (ortholog); cortical actin cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: A-kinase anchor protein 13; A-kinase anchoring protein 13, transcript variant X1; A-kinase anchoring protein 13, transcript variant X2; A-kinase anchoring protein 13, transcript variant X3; A-kinase anchoring protein 13, transcript variant X4; A-kinase anchoring protein 13, transcript variant X5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640134,357,191 - 134,672,629 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648311,661,862 - 11,977,292 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Akap13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640134,357,191 - 134,672,629 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648311,661,862 - 11,977,292 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKAP13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381585,380,603 - 85,749,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1585,380,571 - 85,749,358 (+)EnsemblGRCh38hg38GRCh38
GRCh371585,923,834 - 86,292,589 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361583,724,875 - 84,093,590 (+)NCBINCBI36Build 36hg18NCBI36
Build 341584,021,271 - 84,093,590NCBI
Celera1562,323,846 - 62,692,414 (+)NCBICelera
Cytogenetic Map15q25.3NCBI
HuRef1561,986,401 - 62,354,887 (+)NCBIHuRef
CHM1_11585,765,298 - 86,134,016 (+)NCBICHM1_1
T2T-CHM13v2.01583,132,647 - 83,501,376 (+)NCBIT2T-CHM13v2.0
Akap13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39775,105,271 - 75,404,357 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl775,105,282 - 75,404,357 (+)EnsemblGRCm39 Ensembl
GRCm38775,455,526 - 75,754,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl775,455,534 - 75,754,609 (+)EnsemblGRCm38mm10GRCm38
MGSCv37782,600,420 - 82,899,495 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36775,328,812 - 75,628,122 (+)NCBIMGSCv36mm8
Celera772,913,871 - 73,205,960 (+)NCBICelera
Cytogenetic Map7D1NCBI
cM Map743.76NCBI
Akap13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81138,722,445 - 139,029,401 (+)NCBIGRCr8
mRatBN7.21129,313,183 - 129,619,647 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1129,314,402 - 129,619,646 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1137,232,876 - 137,538,333 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01144,403,105 - 144,708,592 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,289,702 - 137,597,080 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01137,089,558 - 137,315,272 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1137,014,272 - 137,315,272 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01138,007,112 - 138,312,524 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,052,674 - 131,360,512 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11131,302,912 - 131,380,987 (+)NCBI
Celera1121,422,303 - 121,727,463 (+)NCBICelera
Cytogenetic Map1q31NCBI
Akap13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541619,009,485 - 19,247,626 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541619,006,206 - 19,327,523 (-)NCBIChiLan1.0ChiLan1.0
AKAP13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21674,930,726 - 75,292,650 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11578,635,626 - 78,997,324 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01564,076,422 - 64,438,109 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11583,289,867 - 83,651,362 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1583,387,667 - 83,651,362 (+)Ensemblpanpan1.1panPan2
AKAP13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1349,076,313 - 49,310,564 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl349,076,642 - 49,308,221 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha351,631,494 - 51,952,108 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0349,413,000 - 49,733,699 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl349,412,925 - 49,729,970 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1348,911,383 - 49,227,381 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0349,139,636 - 49,460,216 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0349,485,435 - 49,806,458 (+)NCBIUU_Cfam_GSD_1.0
AKAP13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1787,889,384 - 88,222,854 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2794,486,955 - 94,583,014 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AKAP13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1294,009,921 - 4,364,226 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl294,106,732 - 4,359,516 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605942,653,071 - 43,006,115 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Akap13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476812,765,723 - 13,095,136 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476812,767,120 - 13,099,288 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: XM_021722880   ⟹   XP_021578555
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,357,191 - 134,672,629 (-)NCBI
SpeTri2.0NW_00493648311,661,862 - 11,977,292 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021722881   ⟹   XP_021578556
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,361,720 - 134,672,629 (-)NCBI
SpeTri2.0NW_00493648311,661,862 - 11,972,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021722882   ⟹   XP_021578557
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,361,720 - 134,672,629 (-)NCBI
SpeTri2.0NW_00493648311,661,862 - 11,972,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021722883   ⟹   XP_021578558
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,361,720 - 134,672,629 (-)NCBI
SpeTri2.0NW_00493648311,661,862 - 11,972,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021722884   ⟹   XP_021578559
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,361,720 - 134,473,324 (-)NCBI
SpeTri2.0NW_00493648311,861,188 - 11,972,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040275947   ⟹   XP_040131881
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,361,720 - 134,672,629 (-)NCBI
RefSeq Acc Id: XM_040275948   ⟹   XP_040131882
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,357,191 - 134,672,629 (-)NCBI
RefSeq Acc Id: XM_040275949   ⟹   XP_040131883
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,361,720 - 134,672,629 (-)NCBI
RefSeq Acc Id: XM_040275950   ⟹   XP_040131884
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,361,720 - 134,672,629 (-)NCBI
RefSeq Acc Id: XM_040275951   ⟹   XP_040131885
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,361,720 - 134,672,629 (-)NCBI
RefSeq Acc Id: XM_040275952   ⟹   XP_040131886
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640134,361,720 - 134,672,629 (-)NCBI
RefSeq Acc Id: XP_021578555   ⟸   XM_021722880
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021578556   ⟸   XM_021722881
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_021578558   ⟸   XM_021722883
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_021578557   ⟸   XM_021722882
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_021578559   ⟸   XM_021722884
- Peptide Label: isoform X11
- UniProtKB: I3N2H2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040131882   ⟸   XM_040275948
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040131886   ⟸   XM_040275952
- Peptide Label: isoform X7
RefSeq Acc Id: XP_040131884   ⟸   XM_040275950
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040131885   ⟸   XM_040275951
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040131883   ⟸   XM_040275949
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040131881   ⟸   XM_040275947
- Peptide Label: isoform X2
Protein Domains
DH   PH   Phorbol-ester/DAG-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020484 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000025325.2 UniProtKB/TrEMBL
  ENSSTOT00000034436.1 UniProtKB/TrEMBL
  ENSSTOT00000036549.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_16 UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Akap13 ENTREZGENE
PANTHER AGAP007712-PA UniProtKB/TrEMBL
  PTHR13944:SF18 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  PH_16 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48065 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A287D5I3_ICTTR UniProtKB/TrEMBL
  A0A287D7S8_ICTTR UniProtKB/TrEMBL
  I3N2H2 ENTREZGENE, UniProtKB/TrEMBL