Pla2g4b (phospholipase A2 group IVB) - Rat Genome Database

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Gene: Pla2g4b (phospholipase A2 group IVB) Ictidomys tridecemlineatus
Analyze
Symbol: Pla2g4b
Name: phospholipase A2 group IVB
RGD ID: 12672376
Description: ENCODES a protein that exhibits lysophospholipase activity (ortholog); phospholipase A1 activity (ortholog); INVOLVED IN phosphatidylcholine acyl-chain remodeling (ortholog); phosphatidylethanolamine acyl-chain remodeling (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; alpha-linolenic acid metabolic pathway; antipyrine drug pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN early endosome membrane (ortholog); mitochondrial inner membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytosolic phospholipase A2 beta
RGD Orthologs
Human
Rat
Chinchilla
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864087,296,128 - 87,306,698 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364715,145,502 - 5,153,498 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364715,145,736 - 5,153,930 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pla2g4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864087,296,128 - 87,306,698 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364715,145,502 - 5,153,498 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364715,145,736 - 5,153,930 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA2G4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381541,838,847 - 41,848,143 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1541,837,775 - 41,848,147 (+)EnsemblGRCh38hg38GRCh38
GRCh371542,131,045 - 42,140,341 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361542,131,011 - 42,140,346 (+)NCBINCBI36Build 36hg18NCBI36
Build 341539,907,605 - 39,927,630NCBI
Celera1518,898,654 - 18,907,988 (+)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1518,979,399 - 18,988,734 (+)NCBIHuRef
CHM1_11542,249,484 - 42,258,819 (+)NCBICHM1_1
T2T-CHM13v2.01539,644,798 - 39,654,098 (+)NCBIT2T-CHM13v2.0
Pla2g4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,458,022 - 127,467,637 (+)NCBIGRCr8
mRatBN7.23107,004,238 - 107,013,853 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,005,489 - 107,013,853 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3110,680,642 - 110,689,006 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03119,276,197 - 119,284,561 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03116,936,590 - 116,944,954 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03111,824,919 - 111,833,526 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3111,825,162 - 111,834,210 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,372,716 - 118,382,163 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43106,540,155 - 106,548,519 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13106,429,577 - 106,444,575 (+)NCBI
Celera3105,914,984 - 105,923,348 (+)NCBICelera
Cytogenetic Map3q35NCBI
Pla2g4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554168,634,184 - 8,642,833 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554168,633,249 - 8,643,219 (+)NCBIChiLan1.0ChiLan1.0
PLA2G4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1308,865,941 - 8,878,687 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl308,859,257 - 8,876,395 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha308,925,947 - 8,935,469 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0309,001,229 - 9,014,003 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl309,002,061 - 9,014,181 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1308,922,814 - 8,932,335 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0309,026,791 - 9,036,313 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0309,161,786 - 9,171,308 (+)NCBIUU_Cfam_GSD_1.0
PLA2G4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1129,514,346 - 129,524,313 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11129,514,801 - 129,524,365 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21144,556,107 - 144,567,434 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLA2G4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12641,137,643 - 41,147,384 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604899,854,872 - 99,864,616 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pla2g4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248049,016,487 - 9,026,621 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248049,017,154 - 9,026,977 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000000681   ⟹   ENSSTOP00000000611
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364715,145,502 - 5,153,498 (+)Ensembl
RefSeq Acc Id: XM_040275650   ⟹   XP_040131584
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864087,296,128 - 87,306,698 (+)NCBI
RefSeq Acc Id: XM_040275651   ⟹   XP_040131585
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864087,296,128 - 87,306,698 (+)NCBI
RefSeq Acc Id: XM_040275652   ⟹   XP_040131586
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864087,297,424 - 87,306,698 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040131584 (Get FASTA)   NCBI Sequence Viewer  
  XP_040131585 (Get FASTA)   NCBI Sequence Viewer  
  XP_040131586 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000000611.3
GenBank Protein KAG3261667 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040131584   ⟸   XM_040275650
- Peptide Label: isoform X1
- UniProtKB: I3LX52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131585   ⟸   XM_040275651
- Peptide Label: isoform X2
- UniProtKB: I3LX52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131586   ⟸   XM_040275652
- Peptide Label: isoform X3
- UniProtKB: I3LX52 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000000611   ⟸   ENSSTOT00000000681
Protein Domains
C2   PLA2c


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000680 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000681.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
  Cytosolic phospholipase A2 catalytic domain UniProtKB/TrEMBL
InterPro Acyl_Trfase/lysoPLipase UniProtKB/TrEMBL
  C2_cPLA2 UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  cPLA2_C2 UniProtKB/TrEMBL
  LysoPLipase_cat_dom UniProtKB/TrEMBL
NCBI Gene Pla2g4b ENTREZGENE
PANTHER CYTOSOLIC PHOSPHOLIPASE A2 UniProtKB/TrEMBL
  CYTOSOLIC PHOSPHOLIPASE A2 BETA UniProtKB/TrEMBL
Pfam cPLA2_C2 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PLA2_B UniProtKB/TrEMBL
PROSITE PLA2C UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART PLAc UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
  SSF52151 UniProtKB/TrEMBL
UniProt I3LX52 ENTREZGENE, UniProtKB/TrEMBL