Cubn (cubilin) - Rat Genome Database

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Gene: Cubn (cubilin) Ictidomys tridecemlineatus
Analyze
Symbol: Cubn
Name: cubilin
RGD ID: 12664788
Description: ENCODES a protein that exhibits hemoglobin binding (ortholog); identical protein binding (ortholog); INVOLVED IN cobalamin catabolic process (ortholog); endocytic hemoglobin import into cell (ortholog); establishment of localization in cell (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); autism spectrum disorder (ortholog); Chronic Benign Proteinuria (ortholog); FOUND IN apical plasma membrane (ortholog); brush border membrane (ortholog); coated vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934417,550,256 - 17,808,034 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493652010,140,784 - 10,409,851 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493652010,140,784 - 10,410,082 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Cubn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934417,550,256 - 17,808,034 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493652010,140,784 - 10,409,851 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493652010,140,784 - 10,410,082 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CUBN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381016,823,966 - 17,129,811 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1016,823,966 - 17,129,811 (-)EnsemblGRCh38hg38GRCh38
GRCh371016,865,965 - 17,171,810 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361016,905,971 - 17,211,822 (-)NCBINCBI36Build 36hg18NCBI36
Build 341016,906,543 - 17,211,796NCBI
Celera1016,799,178 - 17,105,066 (-)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1016,779,758 - 17,084,998 (-)NCBIHuRef
CHM1_11016,866,152 - 17,171,970 (-)NCBICHM1_1
T2T-CHM13v2.01016,842,423 - 17,148,343 (-)NCBIT2T-CHM13v2.0
Cubn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39213,281,149 - 13,496,687 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl213,281,149 - 13,496,624 (-)EnsemblGRCm39 Ensembl
GRCm38213,276,338 - 13,491,876 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl213,276,338 - 13,491,813 (-)EnsemblGRCm38mm10GRCm38
MGSCv37213,197,965 - 13,413,503 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36213,194,189 - 13,409,729 (-)NCBIMGSCv36mm8
Celera213,186,219 - 13,402,130 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map29.86NCBI
Cubn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81781,293,619 - 81,501,694 (-)NCBIGRCr8
mRatBN7.21776,385,046 - 76,593,133 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1776,385,060 - 76,593,231 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1779,857,681 - 80,065,673 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01783,693,064 - 83,901,073 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01777,740,972 - 77,948,974 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01780,584,921 - 80,807,181 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1780,584,878 - 80,807,243 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01782,205,509 - 82,425,565 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41787,545,893 - 87,772,079 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11787,556,725 - 87,782,912 (-)NCBI
Celera1775,753,959 - 75,962,017 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
Cubn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542910,788,959 - 11,038,845 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542910,789,674 - 11,038,297 (+)NCBIChiLan1.0ChiLan1.0
CUBN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2829,666,975 - 29,981,918 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11029,672,298 - 29,977,993 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01017,141,464 - 17,446,867 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11017,415,551 - 17,719,126 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1017,415,551 - 17,719,129 (-)Ensemblpanpan1.1panPan2
CUBN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1219,784,125 - 20,041,840 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl219,784,198 - 20,041,839 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha216,887,230 - 17,151,382 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0220,075,720 - 20,333,544 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl220,075,720 - 20,333,543 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1217,278,052 - 17,541,754 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0218,116,485 - 18,374,283 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0218,734,135 - 18,999,935 (+)NCBIUU_Cfam_GSD_1.0
CUBN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1043,102,946 - 43,414,758 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11043,102,931 - 43,414,692 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21047,746,354 - 48,023,009 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUBN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1916,774,644 - 17,079,776 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl916,774,757 - 17,079,681 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605122,409,233 - 22,718,741 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cubn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479610,728,983 - 10,988,361 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479610,728,853 - 10,987,292 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000037066   ⟹   ENSSTOP00000027943
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493652010,140,784 - 10,409,851 (+)Ensembl
RefSeq Acc Id: XM_040277856   ⟹   XP_040133790
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934417,550,256 - 17,808,034 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040133790 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000027943.1
Reference Protein Sequences
RefSeq Acc Id: XP_040133790   ⟸   XM_040277856
- UniProtKB: A0A287D313 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000027943   ⟸   ENSSTOT00000037066
Protein Domains
CUB   EGF-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000029820 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000037066.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.290 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro CUB_dom UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  EGF_dom UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Sperma_CUB_dom_sf UniProtKB/TrEMBL
NCBI Gene Cubn ENTREZGENE
PANTHER OVOCHYMASE-RELATED UniProtKB/TrEMBL
Pfam CUB UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  CUB UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
SMART CUB UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF49854 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A287D313 ENTREZGENE, UniProtKB/TrEMBL