Plp1 (proteolipid protein 1) - Rat Genome Database

Name: Plp1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Plp1 (proteolipid protein 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Plp1

Name:

proteolipid protein 1

RGD ID:

12660202

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); protein-containing complex binding (ortholog); structural constituent of myelin sheath (ortholog); INVOLVED IN AMPA selective glutamate receptor signaling pathway (ortholog); astrocyte development (ortholog); axon development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal recessive nonsyndromic deafness 9 (ortholog); Chronic Relapsing Experimental Autoimmune Encephalomyelitis (ortholog); FOUND IN integrin alphav-beta3 complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

proteolipid protein 1, transcript variant X1; proteolipid protein 1, transcript variant X2; proteolipid protein 1, transcript variant X3; proteolipid protein 1, transcript variant X4

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PLP1 (proteolipid protein 1)	NCBI	Ortholog
Mus musculus (house mouse):	Plp1 (proteolipid protein (myelin) 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Plp1 (proteolipid protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Plp1 (proteolipid protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PLP1 (proteolipid protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PLP1 (proteolipid protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PLP1 (proteolipid protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PLP1 (proteolipid protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Plp1 (proteolipid protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	77,107,149 - 77,123,012 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936499	10,534,950 - 10,551,012 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936499	10,534,953 - 10,553,411 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal recessive nonsyndromic deafness 9 (ISO)

Chronic Relapsing Experimental Autoimmune Encephalomyelitis (ISO)

demyelinating disease (ISO)

Developmental Disabilities (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

genetic disease (ISO)

hereditary spastic paraplegia (ISO)

hereditary spastic paraplegia 2 (ISO)

intellectual disability (ISO)

Muscle Spasticity (ISO)

neurotoxicity (ISO)

Pelizaeus-Merzbacher disease (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

visual epilepsy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

AMPA selective glutamate receptor signaling pathway (ISO)

astrocyte development (IEA,ISO)

axon development (IEA,ISO)

axon ensheathment (IEA,ISO)

central nervous system myelination (IEA,ISO)

glial cell differentiation (ISO)

inflammatory response (IEA,ISO)

long-chain fatty acid biosynthetic process (IEA,ISO)

myelination (IEA,ISO)

positive regulation of calcium ion transmembrane transport (ISO)

positive regulation of cell migration (ISO)

positive regulation of gene expression (IEA,ISO)

substantia nigra development (ISO)

Cellular Component

integrin alphav-beta3 complex (ISO)

membrane (IEA)

myelin sheath (IEA)

plasma membrane (IEA)

Molecular Function

identical protein binding (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

structural constituent of myelin sheath (IEA,ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Plp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	77,107,149 - 77,123,012 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936499	10,534,950 - 10,551,012 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936499	10,534,953 - 10,553,411 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	103,776,506 - 103,792,619 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	103,773,718 - 103,792,619 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	103,031,434 - 103,047,548 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	102,918,410 - 102,934,204 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	102,837,898 - 102,853,690	NCBI
Celera	X	103,470,449 - 103,486,558 (+)	NCBI		Celera
Cytogenetic Map	X	q22.2	NCBI
HuRef	X	92,687,547 - 92,703,609 (+)	NCBI		HuRef
CHM1_1	X	102,924,426 - 102,940,535 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	102,223,463 - 102,239,585 (+)	NCBI		T2T-CHM13v2.0

Plp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	135,720,897 - 135,739,331 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	135,723,420 - 135,740,482 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	136,820,148 - 136,838,582 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	136,822,671 - 136,839,733 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	133,357,375 - 133,372,282 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	132,169,200 - 132,184,107 (+)	NCBI		MGSCv36	mm8
Celera	X	120,104,727 - 120,119,592 (+)	NCBI		Celera
Cytogenetic Map	X	F1	NCBI
cM Map	X	59.1	NCBI

Plp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	104,933,921 - 104,993,317 (+)	NCBI		GRCr8
mRatBN7.2	X	100,184,039 - 100,201,035 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	100,185,767 - 100,201,032 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	102,315,950 - 102,331,220 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	105,814,627 - 105,829,894 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	103,383,798 - 103,399,065 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	107,494,326 - 107,511,355 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	107,496,072 - 107,511,348 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	107,379,831 - 107,394,881 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	124,488,627 - 124,503,639 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	124,562,059 - 124,577,072 (+)	NCBI
Celera	X	101,020,110 - 101,035,276 (+)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

Plp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955548	781,015 - 797,935 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955548	781,522 - 797,246 (+)	NCBI	ChiLan1.0	ChiLan1.0

PLP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	103,397,682 - 103,413,776 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	103,401,283 - 103,417,377 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	93,015,098 - 93,031,193 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	103,353,181 - 103,412,513 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	103,353,184 - 103,412,513 (+)	Ensembl	panpan1.1		panPan2

PLP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	77,191,112 - 77,207,772 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	77,191,150 - 77,205,964 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	63,420,093 - 63,434,914 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	78,808,649 - 78,825,317 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	78,808,262 - 78,825,306 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	76,287,255 - 76,302,076 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	77,974,000 - 77,988,806 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	77,741,107 - 77,755,923 (+)	NCBI		UU_Cfam_GSD_1.0

PLP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	84,666,733 - 84,685,058 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	84,676,627 - 84,683,517 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	98,648,731 - 98,655,621 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	91,671,535 - 91,687,693 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	91,671,878 - 91,687,878 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	16,533,357 - 16,552,347 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624954	133,105 - 150,953 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624954	135,065 - 150,911 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005323399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005323400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021725234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021725235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000004065 ⟹ ENSSTOP00000003646

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936499	10,534,950 - 10,551,012 (-)	Ensembl

RefSeq Acc Id:

XM_005323399 ⟹ XP_005323456

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	77,107,149 - 77,123,012 (+)	NCBI
SpeTri2.0	NW_004936499	10,534,953 - 10,550,856 (-)	NCBI

Sequence:

show sequence

GAGGCTGTCCCTTTAAGGGGGTTGGCTGTCAATCAGAAAGCCCTTTTCATTGCTGGAGAAGAGG
ACAAAGATACTCAGAGAGAAAAAGTAAAGGACCGAAGAAGGAGACTGGAGAGACCAGGATCCTT
CCAGCTGAACAAAGTCAGCCGAAAAGCAGACTAGCCAGCCGGCTACAATTGGATTCAGAGTCCC
AAAGACATGGGTTTGTTAGAGTGCTGTGCAAGATGTCTGGTAGGGGCCCCATTTGCTTCCCTGG
TGGCCACTGGATTGTGTTTCTTTGGGGTGGCACTGTTCTGTGGCTGTGGACATGAAGCACTCAC
TGGCACAGAAAAGCTAATTGAGACTTATTTCTCCAAAAACTACCAGGACTATGAGTATCTCATC
AATGTGATCCATGCCTTCCAGTATGTCATCTATGGAACTGCCTCTTTCTTCTTCCTTTATGGAG
CCCTCCTGCTGGCTGAGGGCTTCTACACCACCGGCGCAGTGAGGCAGATCTTTGGCGACTACAA
GACCACCATCTGCGGCAAGGGCCTGAGTGCAACGGTAACAGGGGGCCAGAAGGGGAGGGGTTCC
AGAGGCCAACATCAAGCTCATTCTTTGGAGCGGGTGTGTCATTGTTTGGGAAAATGGCTAGGAC
ATCCCGACAAGTTTGTGGGCATCACCTATGCCCTGACCGTTGTGTGGCTCCTGGTGTTTGCCTG
CTCAGCTGTGCCTGTGTACATTTACTTCAATACATGGACCACCTGCCAGTCTATTGCCTTCCCC
AGCAAGACTTCTGCCAGTATAGGCAGCCTCTGTGCTGATGCCAGAATGTATGGTGTTCTCCCAT
GGAACGCCTTCCCAGGCAAAGTTTGTGGCTCCAACCTTCTGTCCATCTGCAAAACAGCTGAGTT
TCAAATGACCTTCCACCTGTTTATTGCTGCATTTGTGGGGGCTGCAGCCACACTGGTTTCCCTG
CTCACCTTCATGATTGCTGCCACTTACAACTTCGCTGTCCTTAAACTCATGGGCCGAGGCACCA
AGTTCTGATGTTCCATAAAAATCCCCCTTTGTCTAATAGCAAGGCTCTAACCACACAGCCAACA
ATGCTGCGTCTCCCATCTTAACTCTGCCTTTGCCGCTGACTGGCCCTCTTCTTACTTGATGAGT
GTAACAAGAAAGAAGGGTCTTGCAGTGATTAATGTCTCTGTGGACTCTCCCTCTCATGGACCTC
TTTTAGTCATTTTTCTTCACAGCTGGTTCCTGCGAGAAATGGGAAATGCCCGAGAAGGTGACTC
CCCAACTGCAAGTCACAAGGAATGGAGGCTCGAATTCAATTTCCTTATAACTCCTGAGGACCAG
TCAGTGCTTTCTTCTCAAAGGGCACTTCCACTGATAGAAACAAAGTGGAAAGAAAGATGCTCAG
GTAGAGAGAAGGAATGTCCTTGGTCCCCTTGCCATCTAGAGGAGCCAAATATATTCTCCTTGGT
GTACAAAACAGGAAAACCATTCCTGTATCCCTATTACCACTGAAGATAGAAGAAAAAAACAGCA
AAACAATAAGAGCATTTTCCCAAATCTGCCTGTTGCATCTGGGAGAAGGGGGTCAAAGCAAGGA
TCTTTCACCCTTAGAAAGAGAGCGCTGACCCTGATGGTAATGAACTCTTGAAGCCCTAACTCAG
CCAACCTTACTTATAGCATAAGGGAGCGCATAGTGTCTGTGTAGACAAAGAGGGCATCTAGCCT
TACACCTCTTTAGGAAGAGAAACAGGGTGTTGTCAGCATCTTCTCACTCCCTTCTCCTTGATAA
CAGCTACCATGACAACCCTGTGGTTTCCAAGGAGCTGAGAATAGAAAGAAACTAGCTTATGGGA
AAAACAGACTGGTCTAAGGAGCAGCAGTTACTGTTGGCTAACGGTGTAACTCAAGATGGCCCTC
TGGTAGACACAGGATAGATAACTTTTTGGATAGCATGTCTTTTTTCTGTTAATTAGTTGTGTAC
TCTGGCCTCTGTCATATCTTCACAATGGTGCTCTTTTCATGGGGTTTTATCCATTCAGTCATAG
TAGGTGATTTGAAGATCTTGATTTGTTTCAGAATGATGCACATTTCACAGTTTCCAGTTTGTTT
ATTGCTTGTTTGGGGTTGTAACAGAAAGGGCTAGAGAATGATTTTTGGATTATAATTCTTTTAG
AAAGAGGAAAGTTGAAGAGTAAGCATAACAAATGATATTTACAATTAGCTAGTTGCTTGAATCT
GTTGGAATTTTCTACAAATATTCTGCTGTTTGCAGAAACAGATCTGATGAATCTGAACCTCAAT
TTGAATAACCTGTTTGATCGTTCTTTCTAGCTAATGGGAGATGATTTACTTAGCAGTGTTTTCT
TGGTGTGTTAAAAGTTAGGTTTAATGTAGAGGTTATTTTCTTCTGGTATAGATCACATAATAGA
ATGTACCAGCTGTCAGCTATTCAGTTAGTAAGCTTCCATGGAAAAGGACAGAAAGAGTTTAAAT
CTGAGTAGTTCCCAGTCTTTTCCTGTTTTTGTTAACTTTGGGTAGATAAACTTATCTGATTGGT
TGTTATTGAAAGGACAGTTTCTACTGTAGCTCTTTTGTTGTAAAGAGTTACTTTCTCTTTTCCC
CAAAAGTGGTCTCAGCAATGTTTAAGGAGATACAAAATCTTTACAAAAAGACACTGATACTTGT
TTTCAGACCAGTATACAAGATAAGCTTCCAGGCTGCATAGAGGAAGGAGAGGGAAAAAGTTCTA
TGAGAAACCAATCAAGATCAAGGGAAGTGAAGTAATCTGTACCTTGTGTTTTATTTTTATTTAA
TAACATAGTAAGTAACCAACCCTCCCCTGAAAACCTCACATGCATACATACACACATGTACACA
CACAAAGAGAGTTAATCAACTGAAAGTGTTTCCTTCATTTCTGATATAGAATTTCAATTTTAAC
ACACATAAGGAATAAACTTTTAGAAACTTATCTTACAAAATGTATTTTATAAAATTAAAGAAAA
TAAAATTAAGAATGTTCTCAA

hide sequence

RefSeq Acc Id:

XM_005323400 ⟹ XP_005323457

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	77,107,149 - 77,123,012 (+)	NCBI
SpeTri2.0	NW_004936499	10,534,953 - 10,550,856 (-)	NCBI

Sequence:

show sequence

GAGGCTGTCCCTTTAAGGGGGTTGGCTGTCAATCAGAAAGCCCTTTTCATTGCTGGAGAAGAGG
ACAAAGATACTCAGAGAGAAAAAGTAAAGGACCGAAGAAGGAGACTGGAGAGACCAGGATCCTT
CCAGCTGAACAAAGTCAGCCGAAAAGCAGACTAGCCAGCCGGCTACAATTGGATTCAGAGTCCC
AAAGACATGGGTTTGTTAGAGTGCTGTGCAAGATGTCTGGTAGGGGCCCCATTTGCTTCCCTGG
TGGCCACTGGATTGTGTTTCTTTGGGGTGGCACTGTTCTGTGGCTGTGGACATGAAGCACTCAC
TGGCACAGAAAAGCTAATTGAGACTTATTTCTCCAAAAACTACCAGGACTATGAGTATCTCATC
AATGTGATCCATGCCTTCCAGTATGTCATCTATGGAACTGCCTCTTTCTTCTTCCTTTATGGAG
CCCTCCTGCTGGCTGAGGGCTTCTACACCACCGGCGCAGTGAGGCAGATCTTTGGCGACTACAA
GACCACCATCTGCGGCAAGGGCCTGAGTGCAACGTTTGTGGGCATCACCTATGCCCTGACCGTT
GTGTGGCTCCTGGTGTTTGCCTGCTCAGCTGTGCCTGTGTACATTTACTTCAATACATGGACCA
CCTGCCAGTCTATTGCCTTCCCCAGCAAGACTTCTGCCAGTATAGGCAGCCTCTGTGCTGATGC
CAGAATGTATGGTGTTCTCCCATGGAACGCCTTCCCAGGCAAAGTTTGTGGCTCCAACCTTCTG
TCCATCTGCAAAACAGCTGAGTTTCAAATGACCTTCCACCTGTTTATTGCTGCATTTGTGGGGG
CTGCAGCCACACTGGTTTCCCTGCTCACCTTCATGATTGCTGCCACTTACAACTTCGCTGTCCT
TAAACTCATGGGCCGAGGCACCAAGTTCTGATGTTCCATAAAAATCCCCCTTTGTCTAATAGCA
AGGCTCTAACCACACAGCCAACAATGCTGCGTCTCCCATCTTAACTCTGCCTTTGCCGCTGACT
GGCCCTCTTCTTACTTGATGAGTGTAACAAGAAAGAAGGGTCTTGCAGTGATTAATGTCTCTGT
GGACTCTCCCTCTCATGGACCTCTTTTAGTCATTTTTCTTCACAGCTGGTTCCTGCGAGAAATG
GGAAATGCCCGAGAAGGTGACTCCCCAACTGCAAGTCACAAGGAATGGAGGCTCGAATTCAATT
TCCTTATAACTCCTGAGGACCAGTCAGTGCTTTCTTCTCAAAGGGCACTTCCACTGATAGAAAC
AAAGTGGAAAGAAAGATGCTCAGGTAGAGAGAAGGAATGTCCTTGGTCCCCTTGCCATCTAGAG
GAGCCAAATATATTCTCCTTGGTGTACAAAACAGGAAAACCATTCCTGTATCCCTATTACCACT
GAAGATAGAAGAAAAAAACAGCAAAACAATAAGAGCATTTTCCCAAATCTGCCTGTTGCATCTG
GGAGAAGGGGGTCAAAGCAAGGATCTTTCACCCTTAGAAAGAGAGCGCTGACCCTGATGGTAAT
GAACTCTTGAAGCCCTAACTCAGCCAACCTTACTTATAGCATAAGGGAGCGCATAGTGTCTGTG
TAGACAAAGAGGGCATCTAGCCTTACACCTCTTTAGGAAGAGAAACAGGGTGTTGTCAGCATCT
TCTCACTCCCTTCTCCTTGATAACAGCTACCATGACAACCCTGTGGTTTCCAAGGAGCTGAGAA
TAGAAAGAAACTAGCTTATGGGAAAAACAGACTGGTCTAAGGAGCAGCAGTTACTGTTGGCTAA
CGGTGTAACTCAAGATGGCCCTCTGGTAGACACAGGATAGATAACTTTTTGGATAGCATGTCTT
TTTTCTGTTAATTAGTTGTGTACTCTGGCCTCTGTCATATCTTCACAATGGTGCTCTTTTCATG
GGGTTTTATCCATTCAGTCATAGTAGGTGATTTGAAGATCTTGATTTGTTTCAGAATGATGCAC
ATTTCACAGTTTCCAGTTTGTTTATTGCTTGTTTGGGGTTGTAACAGAAAGGGCTAGAGAATGA
TTTTTGGATTATAATTCTTTTAGAAAGAGGAAAGTTGAAGAGTAAGCATAACAAATGATATTTA
CAATTAGCTAGTTGCTTGAATCTGTTGGAATTTTCTACAAATATTCTGCTGTTTGCAGAAACAG
ATCTGATGAATCTGAACCTCAATTTGAATAACCTGTTTGATCGTTCTTTCTAGCTAATGGGAGA
TGATTTACTTAGCAGTGTTTTCTTGGTGTGTTAAAAGTTAGGTTTAATGTAGAGGTTATTTTCT
TCTGGTATAGATCACATAATAGAATGTACCAGCTGTCAGCTATTCAGTTAGTAAGCTTCCATGG
AAAAGGACAGAAAGAGTTTAAATCTGAGTAGTTCCCAGTCTTTTCCTGTTTTTGTTAACTTTGG
GTAGATAAACTTATCTGATTGGTTGTTATTGAAAGGACAGTTTCTACTGTAGCTCTTTTGTTGT
AAAGAGTTACTTTCTCTTTTCCCCAAAAGTGGTCTCAGCAATGTTTAAGGAGATACAAAATCTT
TACAAAAAGACACTGATACTTGTTTTCAGACCAGTATACAAGATAAGCTTCCAGGCTGCATAGA
GGAAGGAGAGGGAAAAAGTTCTATGAGAAACCAATCAAGATCAAGGGAAGTGAAGTAATCTGTA
CCTTGTGTTTTATTTTTATTTAATAACATAGTAAGTAACCAACCCTCCCCTGAAAACCTCACAT
GCATACATACACACATGTACACACACAAAGAGAGTTAATCAACTGAAAGTGTTTCCTTCATTTC
TGATATAGAATTTCAATTTTAACACACATAAGGAATAAACTTTTAGAAACTTATCTTACAAAAT
GTATTTTATAAAATTAAAGAAAATAAAATTAAGAATGTTCTCAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005323456	(Get FASTA)	NCBI Sequence Viewer
	XP_005323457	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000003646.3
GenBank Protein	KAG3272670	(Get FASTA)	NCBI Sequence Viewer
	KAG3272671	(Get FASTA)	NCBI Sequence Viewer
	KAG3272672	(Get FASTA)	NCBI Sequence Viewer
	KAG3272673	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005323457 ⟸ XM_005323400

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINV
IHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATFVGITYALTVVW
LLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSI
CKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF

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RefSeq Acc Id:	XP_005323456 ⟸ XM_005323399
- Peptide Label:	isoform X1
- UniProtKB:	I3M3J2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINV IHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRG QHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSK TSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLT FMIAATYNFAVLKLMGRGTKF hide sequence

RefSeq Acc Id:

ENSSTOP00000003646 ⟸ ENSSTOT00000004065

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000004055	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000004065.3	UniProtKB/TrEMBL
InterPro	Myelin_PLP	UniProtKB/TrEMBL
	Myelin_PLP_CS	UniProtKB/TrEMBL
NCBI Gene	Plp1	ENTREZGENE
PANTHER	MYELIN PROTEOLIPID PROTEIN	UniProtKB/TrEMBL
	PTHR11683	UniProtKB/TrEMBL
Pfam	Myelin_PLP	UniProtKB/TrEMBL
PRINTS	MYELINPLP	UniProtKB/TrEMBL
PROSITE	MYELIN_PLP_1	UniProtKB/TrEMBL
	MYELIN_PLP_2	UniProtKB/TrEMBL
SMART	PLP	UniProtKB/TrEMBL
UniProt	I3M3J2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM