Rps6ka6 (ribosomal protein S6 kinase A6)

Gene: Rps6ka6 (ribosomal protein S6 kinase A6) Ictidomys tridecemlineatus

Analyze

Symbol:

Rps6ka6

Name:

ribosomal protein S6 kinase A6

RGD ID:

12645411

Description:

ENCODES a protein that exhibits ATP binding (inferred); magnesium ion binding (inferred); protein serine kinase activity (inferred); INVOLVED IN negative regulation of embryonic development (ortholog); negative regulation of ERK1 and ERK2 cascade (ortholog); negative regulation of mesoderm development (ortholog); PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); FOUND IN synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ribosomal protein S6 kinase A6, transcript variant X1; ribosomal protein S6 kinase A6, transcript variant X2; ribosomal protein S6 kinase A6, transcript variant X3; ribosomal protein S6 kinase alpha-6

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	58,533,568 - 58,632,733 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936547	4,857,685 - 4,975,222 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936547	4,846,012 - 4,952,773 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator (IEA)

intracellular signal transduction (IEA)

negative regulation of embryonic development (ISO)

negative regulation of ERK1 and ERK2 cascade (ISO)

negative regulation of mesoderm development (ISO)

Cellular Component

fibrillar center (IEA)

mitochondrion (IEA)

nucleolus (IEA)

nucleoplasm (IEA)

synapse (ISO)

Molecular Function

ATP binding (IEA)

magnesium ion binding (IEA)

protein binding (ISO)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

the extracellular signal-regulated Raf/Mek/Erk signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Rps6ka6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	58,533,568 - 58,632,733 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936547	4,857,685 - 4,975,222 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936547	4,846,012 - 4,952,773 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RPS6KA6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	84,058,346 - 84,188,499 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	84,058,346 - 84,206,356 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	83,313,354 - 83,443,207 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	83,205,640 - 84,362,350 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	83,125,128 - 83,254,098	NCBI
Celera	X	83,550,763 - 83,681,714 (-)	NCBI		Celera
Cytogenetic Map	X	q21.1	NCBI
HuRef	X	76,885,898 - 76,994,131 (-)	NCBI		HuRef
CHM1_1	X	83,207,273 - 83,336,842 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	82,493,471 - 82,624,675 (-)	NCBI		T2T-CHM13v2.0

Rps6ka6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	110,297,534 - 110,447,794 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	110,297,889 - 110,447,656 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	111,387,837 - 111,538,097 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	111,388,192 - 111,537,959 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	108,501,801 - 108,651,554 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	107,505,136 - 107,654,889 (-)	NCBI		MGSCv36	mm8
Celera	X	98,071,699 - 98,217,087 (-)	NCBI		Celera
Cytogenetic Map	X	E1	NCBI
cM Map	X	48.2	NCBI

Rps6ka6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	80,537,723 - 80,638,910 (-)	NCBI		GRCr8
mRatBN7.2	X	76,353,316 - 76,454,502 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	76,353,760 - 76,454,484 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	77,992,847 - 78,092,386 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	81,429,108 - 81,528,641 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	79,015,930 - 79,115,471 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	82,641,679 - 82,743,771 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	82,641,687 - 82,743,753 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	82,609,740 - 82,710,719 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	99,798,274 - 99,901,585 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	77,660,385 - 77,759,926 (-)	NCBI		Celera
Cytogenetic Map	X	q31	NCBI

Rps6ka6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955529	3,149,407 - 3,296,105 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955529	3,115,652 - 3,296,505 (-)	NCBI	ChiLan1.0	ChiLan1.0

RPS6KA6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	83,538,403 - 83,668,923 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	83,542,013 - 83,672,536 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	73,131,457 - 73,261,906 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	83,242,717 - 83,373,450 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	83,243,957 - 83,373,194 (-)	Ensembl	panpan1.1		panPan2

RPS6KA6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	64,915,871 - 65,111,095 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	64,921,230 - 65,111,116 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	55,672,366 - 55,868,014 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	66,239,816 - 66,439,714 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	66,244,041 - 66,439,719 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	63,893,818 - 64,089,422 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	65,525,394 - 65,721,255 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	65,099,716 - 65,295,248 (-)	NCBI		UU_Cfam_GSD_1.0

RPS6KA6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	67,236,473 - 67,415,010 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	67,234,684 - 67,415,114 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	77,099,566 - 77,278,238 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RPS6KA6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	72,942,352 - 73,081,174 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	72,942,648 - 73,080,887 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666067	7,794,891 - 7,927,152 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rps6ka6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624852	4,287,855 - 4,482,373 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624852	4,287,104 - 4,492,128 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005328833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005328834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021728767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040282649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040282656	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040282659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040282677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040282679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000002297 ⟹ ENSSTOP00000002054

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936547	4,859,384 - 4,950,506 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000032326 ⟹ ENSSTOP00000027385

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936547	4,857,685 - 4,952,907 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000033254 ⟹ ENSSTOP00000025820

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936547	4,859,384 - 4,952,907 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000041134 ⟹ ENSSTOP00000031479

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936547	4,859,384 - 4,975,222 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000042049 ⟹ ENSSTOP00000027705

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936547	4,859,384 - 4,952,240 (-)	Ensembl

RefSeq Acc Id:

XM_005328833 ⟹ XP_005328890

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	58,533,568 - 58,632,338 (-)	NCBI
SpeTri2.0	NW_004936547	4,846,012 - 4,952,773 (-)	NCBI

Sequence:

show sequence

GGCGCTAGCAGTGGCTTTTACTACTCTTCACCCGCCTCCCTCGCCTAGCACGCCCCCCTCCCCT
CTTTCCCACCCCCACCACGCGGTCCCCCGCATTCACCCCGCCCCTCTTTCCCACCCCCCTCACC
CCAGTCTGGGGAATCTCCATTGACGTTCGGGTGACGCCGCCGTGCTGCCGCCGTGGGGGGTTCC
AGGCGCCGCACAGCAGTGTGCGGCGGAGACCCCCGGGTCCCAGCCTCTGAGGGACCCCGCTGCG
AGGGCAGCGGTCGCTGAAGGCGGGGCTGGGGGTCACAGCAGAGACGGCGGTGGCAGCAGCGGGC
CAGTTCAATAGACAGGATGCACTGCCGCGCAGGCGGTCCGCAGCTCCTGTTCGAGTGCTCCTGA
AAGCGCGATGCTACCAATCCCTCCTCAGGAAGAGCCCTGGGACCAAGACATGGAGGTGTTCGGT
GGCGGCGGCGGCGGCACGAACAGTGGCGAGGTAAATGGTCTTAAAATGGTTGATGAGCCAATGG
AAGAGGGAGAAGCAGATTCTTGCCTTGATGAAGGTGTGGTTAAAGAAATCCCTATCATTCACCA
TGTTAAGGAAGGTTATGAGAAAGCAGATCCTGCACAATTTGAGTTGCTCAAGGTTCTTGGTCAG
GGATCATTTGGAAAGGTGTTTCTGGTTAGAAAGAAGACTGGACCTGATGCTGGACAGCTCTATG
CAATGAAGGTGTTAAAAAAAGCTTCTTTAAAAGTTCGAGACCGAGTTCGGACAAAGATGGAGAG
GGATATACTGGTGGAAGTAAATCATCCATTTATTGTCAAACTGCACTATGCTTTTCAGACTGAA
GGGAAGCTGTATTTAATATTGGATTTTCTCAGGGGAGGAGATGTCTTTACAAGATTATCCAAAG
AGGTTCTGTTTACAGAGGAAGATGTGAAATTTTACCTCGCAGAACTGGCCCTTGCTTTGGATCA
TCTGCATCAATTAGGAATTGTATATAGAGACCTGAAGCCAGAAAACATTTTGCTTGATGAAATA
GGACATATCAAGTTAACAGACTTTGGACTCAGCAAGGAGTCAGTAGATCAGGAAAAGAAGGCCT
ACTCATTTTGTGGTACAGTGGAGTATATGGCTCCTGAAGTAGTAAATAGGAGAGGCCATTCACA
GAGTGCTGATTGGTGGTCATATGGTGTACTTATGTTTGAAATGCTTACTGGTACTCTGCCATTT
CAAGGTAAAGACAGAAATGAGACCATGAATATGATATTAAAAGCAAAACTTGGAATGCCTCAGT
TTCTTAGTGCTGAAGCACAGAGTCTTCTAAGGATGTTATTCAAAAGAAATCCATCAAATAGATT
AGGTTCAGAAGGAGTTGAGGAAATTAAAAGACATCTTTTTTTTGCAAATATTGACTGGAATAAA
TTATATAAAAGAGAAGTTCAACCACCTTTCAAACCTGCTTCTGGAAAACCAGATGATACTTTTT
GTTTTGATCCTGAATTTACTGCAAAAACGCCCAAAGATTCTCCTGGTTTGCCAGCTAGTGCAAA
TGCTCATCAGCTTTTCAAAGGATTTAGCTTTGTTGCAACTTCTATTGCCGAAGAATATAAAATC
ACTCCAATCATAAGTGCAAACGTATTGCCAGTTGTTCAGATAAATGGAAATGCTGCACAATTTG
GTGAAATATATGAATTGAAAGAGGATATTGGTGTTGGCTCTTATTCTGTTTGCAAGCGATGTAT
ACATACAGCTACCAACTTGGAATTTGCAGTGAAGATCATTGACAAAAGTAAGCGAGACCCCTCA
GAAGAAATTGAAATTTTGATGCGCTATGGACAGCATCCCAACATTATTACTTTAAAGGATGTCT
TTGATGATGGTAGATATGTTTACCTTGTTACGGATTTGATGAAAGGAGGAGAACTACTGGACCG
TATTCTCAAGCAAAAATGTTTCTCAGAACAGGAAGCTAGTGATGTACTGTATGTAATAACTAAG
ACAGTTGATTATCTTCATTGTCAAGGAGTTGTTCATCGTGATCTTAAACCTAGTAATATTTTAT
ACATGGATGAATCAGCGAATGCAGATTCAATTAGGATCTGTGATTTTGGGTTTGCAAAACAACT
TCGAGGAGAAAATGGACTTCTCTTAACTCCCTGCTACACTGCAAACTTTGTAGCACCTGAGGTT
CTTATGCAGCAGGGATATGATGCTGCTTGTGATATTTGGAGTTTAGGAGTCCTTTTTTACACGA
TGTTGGCTGGCTACACTCCATTTGCTAATGGCCCCAATGATACTCCTGAAGAGATACTGCTTCG
TATAGGCAATGGCAAGTTCTCTTTGAGTGGTGGAAACTGGGATAATATTTCAGATGGAGCAAAG
GATTTGCTTTCCCATATGCTTCATATGGACCCTCATCAGAGATACACTACTGAACAAGTATTAA
AGCACTCATGGATAACCCACAGGGATCAGCTGCCGAATGATCAGCCAAATAGAAATGATTCATC
ACACATTGTTAAGGGAGAAGTTGTTGCCACATATTCTGCCCTGACTCACAAGACTTTTCAACCA
ATCCTAGAGCCTGTAGCTGCTTCAAGCTTAGCTCAGCGACGGAGCATGAAAAAGCGAACATCAA
CTGGCTTGGTCTGTTTGACTGGAGCATCCGTAGCGCTGAGGCGCTGAGTCATGGCAGTTTGGCG
GCGAGAAGCTGACAATCAGCCAGAAACTGCGTATGGAGAGCCTGAATTTACCCGCTCCGGGCTT
GGTGTGGGTTCTGAGGGGCGCAGACTGCTCACCCCAGGACCACTTCACCCCAGCATTGCCAAGT
GATCCTGAGCAAACAACATTCAGTTGGTTTAAGACTCCCTTTGCCCGCACAGCTGAAGAGGTCA
CAGAATTGATCTTTTAGCGCCTGCTGCCATGTTGGATCTCCATTGAACATTTTTTTTACCTTCT
CTGATGTCTTTGCTGGCCCATTGTCGGGTTCTATATGATGGCAATACCTGATTCAAACCATACT
TCCTCTAAGGTTTAACTTTTAGCACTCAGAGGTAGAGACAATGGCATAAGAAATATTTGAACTG
AAAGTGGGAAGAGCTTGAATACTTCTGATAGAAATTGATTATTATAACTAGGATAAGAACAAAT
GGATGGTGGATAAGAAATCATGTTTTCTATTCTTTTGACTGCCCAATATCCCTTGCAAGGACAC
ACTTTTTAAAATATTTATGCCTATATAAATTGCATATATGGTACTGCTCTTCCCCAAACAGTAT
ACCAAATCTCTTCCACTTTTGTAATGTACCAAGAACTCTTAAGTGATGTATAGTTCTCTTAGGT
AAAATTGCTAGATGACTTAGAGCTAAGGGTTTTTGTTGTT

hide sequence

RefSeq Acc Id:

XM_021728767 ⟹ XP_021584442

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	58,533,568 - 58,632,335 (-)	NCBI
SpeTri2.0	NW_004936547	4,846,012 - 4,952,772 (-)	NCBI

Sequence:

show sequence

GCGCTAGCAGTGGCTTTTACTACTCTTCACCCGCCTCCCTCGCCTAGCACGCCCCCCTCCCCTC
TTTCCCACCCCCACCACGCGGTCCCCCGCATTCACCCCGCCCCTCTTTCCCACCCCCCTCACCC
CAGTCTGGGGAATCTCCATTGACGTTCGGGTGACGCCGCCGTGCTGCCGCCGTGGGGGGTTCCA
GGCGCCGCACAGGTAAATGGTCTTAAAATGGTTGATGAGCCAATGGAAGAGGGAGAAGCAGATT
CTTGCCTTGATGAAGGTGTGGTTAAAGAAATCCCTATCATTCACCATGTTAAGGAAGGTTATGA
GAAAGCAGATCCTGCACAATTTGAGTTGCTCAAGGTTCTTGGTCAGGGATCATTTGGAAAGGTG
TTTCTGGTTAGAAAGAAGACTGGACCTGATGCTGGACAGCTCTATGCAATGAAGGTGTTAAAAA
AAGCTTCTTTAAAAGTTCGAGACCGAGTTCGGACAAAGATGGAGAGGGATATACTGGTGGAAGT
AAATCATCCATTTATTGTCAAACTGCACTATGCTTTTCAGACTGAAGGGAAGCTGTATTTAATA
TTGGATTTTCTCAGGGGAGGAGATGTCTTTACAAGATTATCCAAAGAGGTTCTGTTTACAGAGG
AAGATGTGAAATTTTACCTCGCAGAACTGGCCCTTGCTTTGGATCATCTGCATCAATTAGGAAT
TGTATATAGAGACCTGAAGCCAGAAAACATTTTGCTTGATGAAATAGGACATATCAAGTTAACA
GACTTTGGACTCAGCAAGGAGTCAGTAGATCAGGAAAAGAAGGCCTACTCATTTTGTGGTACAG
TGGAGTATATGGCTCCTGAAGTAGTAAATAGGAGAGGCCATTCACAGAGTGCTGATTGGTGGTC
ATATGGTGTACTTATGTTTGAAATGCTTACTGGTACTCTGCCATTTCAAGGTAAAGACAGAAAT
GAGACCATGAATATGATATTAAAAGCAAAACTTGGAATGCCTCAGTTTCTTAGTGCTGAAGCAC
AGAGTCTTCTAAGGATGTTATTCAAAAGAAATCCATCAAATAGATTAGGTTCAGAAGGAGTTGA
GGAAATTAAAAGACATCTTTTTTTTGCAAATATTGACTGGAATAAATTATATAAAAGAGAAGTT
CAACCACCTTTCAAACCTGCTTCTGGAAAACCAGATGATACTTTTTGTTTTGATCCTGAATTTA
CTGCAAAAACGCCCAAAGATTCTCCTGGTTTGCCAGCTAGTGCAAATGCTCATCAGCTTTTCAA
AGGATTTAGCTTTGTTGCAACTTCTATTGCCGAAGAATATAAAATCACTCCAATCATAAGTGCA
AACGTATTGCCAGTTGTTCAGATAAATGGAAATGCTGCACAATTTGGTGAAATATATGAATTGA
AAGAGGATATTGGTGTTGGCTCTTATTCTGTTTGCAAGCGATGTATACATACAGCTACCAACTT
GGAATTTGCAGTGAAGATCATTGACAAAAGTAAGCGAGACCCCTCAGAAGAAATTGAAATTTTG
ATGCGCTATGGACAGCATCCCAACATTATTACTTTAAAGGATGTCTTTGATGATGGTAGATATG
TTTACCTTGTTACGGATTTGATGAAAGGAGGAGAACTACTGGACCGTATTCTCAAGCAAAAATG
TTTCTCAGAACAGGAAGCTAGTGATGTACTGTATGTAATAACTAAGACAGTTGATTATCTTCAT
TGTCAAGGAGTTGTTCATCGTGATCTTAAACCTAGTAATATTTTATACATGGATGAATCAGCGA
ATGCAGATTCAATTAGGATCTGTGATTTTGGGTTTGCAAAACAACTTCGAGGAGAAAATGGACT
TCTCTTAACTCCCTGCTACACTGCAAACTTTGTAGCACCTGAGGTTCTTATGCAGCAGGGATAT
GATGCTGCTTGTGATATTTGGAGTTTAGGAGTCCTTTTTTACACGATGTTGGCTGGCTACACTC
CATTTGCTAATGGCCCCAATGATACTCCTGAAGAGATACTGCTTCGTATAGGCAATGGCAAGTT
CTCTTTGAGTGGTGGAAACTGGGATAATATTTCAGATGGAGCAAAGGATTTGCTTTCCCATATG
CTTCATATGGACCCTCATCAGAGATACACTACTGAACAAGTATTAAAGCACTCATGGATAACCC
ACAGGGATCAGCTGCCGAATGATCAGCCAAATAGAAATGATTCATCACACATTGTTAAGGGAGA
AGTTGTTGCCACATATTCTGCCCTGACTCACAAGACTTTTCAACCAATCCTAGAGCCTGTAGCT
GCTTCAAGCTTAGCTCAGCGACGGAGCATGAAAAAGCGAACATCAACTGGCTTGGTCTGTTTGA
CTGGAGCATCCGTAGCGCTGAGGCGCTGAGTCATGGCAGTTTGGCGGCGAGAAGCTGACAATCA
GCCAGAAACTGCGTATGGAGAGCCTGAATTTACCCGCTCCGGGCTTGGTGTGGGTTCTGAGGGG
CGCAGACTGCTCACCCCAGGACCACTTCACCCCAGCATTGCCAAGTGATCCTGAGCAAACAACA
TTCAGTTGGTTTAAGACTCCCTTTGCCCGCACAGCTGAAGAGGTCACAGAATTGATCTTTTAGC
GCCTGCTGCCATGTTGGATCTCCATTGAACATTTTTTTTACCTTCTCTGATGTCTTTGCTGGCC
CATTGTCGGGTTCTATATGATGGCAATACCTGATTCAAACCATACTTCCTCTAAGGTTTAACTT
TTAGCACTCAGAGGTAGAGACAATGGCATAAGAAATATTTGAACTGAAAGTGGGAAGAGCTTGA
ATACTTCTGATAGAAATTGATTATTATAACTAGGATAAGAACAAATGGATGGTGGATAAGAAAT
CATGTTTTCTATTCTTTTGACTGCCCAATATCCCTTGCAAGGACACACTTTTTAAAATATTTAT
GCCTATATAAATTGCATATATGGTACTGCTCTTCCCCAAACAGTATACCAAATCTCTTCCACTT
TTGTAATGTACCAAGAACTCTTAAGTGATGTATAGTTCTCTTAGGTAAAATTGCTAGATGACTT
AGAGCTAAGGGTTTTTGTTGTT

hide sequence

RefSeq Acc Id:

XM_040282649 ⟹ XP_040138583

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	58,533,568 - 58,632,338 (-)	NCBI

RefSeq Acc Id:

XM_040282656 ⟹ XP_040138590

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	58,533,568 - 58,632,060 (-)	NCBI

RefSeq Acc Id:

XM_040282659 ⟹ XP_040138593

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	58,533,568 - 58,632,337 (-)	NCBI

RefSeq Acc Id:

XM_040282677 ⟹ XP_040138611

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	58,533,568 - 58,632,721 (-)	NCBI

RefSeq Acc Id:

XM_040282679 ⟹ XP_040138613

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	58,533,568 - 58,632,733 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005328890	(Get FASTA)	NCBI Sequence Viewer
	XP_021584442	(Get FASTA)	NCBI Sequence Viewer
	XP_040138583	(Get FASTA)	NCBI Sequence Viewer
	XP_040138590	(Get FASTA)	NCBI Sequence Viewer
	XP_040138593	(Get FASTA)	NCBI Sequence Viewer
	XP_040138611	(Get FASTA)	NCBI Sequence Viewer
	XP_040138613	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000002054.3
	ENSSTOP00000025820.1
	ENSSTOP00000027385.1
	ENSSTOP00000027705.1
	ENSSTOP00000031479.1
GenBank Protein	KAG3272506	(Get FASTA)	NCBI Sequence Viewer
	KAG3272507	(Get FASTA)	NCBI Sequence Viewer
	KAG3272508	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005328890 ⟸ XM_005328833
- Peptide Label:	isoform X1
- UniProtKB:	A0A287CWW4 (UniProtKB/TrEMBL), A0A287D2G6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLPIPPQEEPWDQDMEVFGGGGGGTNSGEVNGLKMVDEPMEEGEADSCLDEGVVKEIPIIHHVK EGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDI LVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH QLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSA DWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPSNRLGS EGVEEIKRHLFFANIDWNKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTPKDSPGLPASANAH QLFKGFSFVATSIAEEYKITPIISANVLPVVQINGNAAQFGEIYELKEDIGVGSYSVCKRCIHT ATNLEFAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRIL KQKCFSEQEASDVLYVITKTVDYLHCQGVVHRDLKPSNILYMDESANADSIRICDFGFAKQLRG ENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIG NGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTTEQVLKHSWITHRDQLPNDQPNRNDSSHI VKGEVVATYSALTHKTFQPILEPVAASSLAQRRSMKKRTSTGLVCLTGASVALRR hide sequence

RefSeq Acc Id:	XP_021584442 ⟸ XM_021728767
- Peptide Label:	isoform X4
- UniProtKB:	A0A287D2G6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVDEPMEEGEADSCLDEGVVKEIPIIHHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGP DAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDV FTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESV DQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKA KLGMPQFLSAEAQSLLRMLFKRNPSNRLGSEGVEEIKRHLFFANIDWNKLYKREVQPPFKPASG KPDDTFCFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPIISANVLPVVQIN GNAAQFGEIYELKEDIGVGSYSVCKRCIHTATNLEFAVKIIDKSKRDPSEEIEILMRYGQHPNI ITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEQEASDVLYVITKTVDYLHCQGVVHRDL KPSNILYMDESANADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSL GVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRY TTEQVLKHSWITHRDQLPNDQPNRNDSSHIVKGEVVATYSALTHKTFQPILEPVAASSLAQRRS MKKRTSTGLVCLTGASVALRR hide sequence

RefSeq Acc Id:	XP_040138613 ⟸ XM_040282679
- Peptide Label:	isoform X4
- UniProtKB:	A0A287D2G6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040138611 ⟸ XM_040282677
- Peptide Label:	isoform X4
- UniProtKB:	A0A287D2G6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040138583 ⟸ XM_040282649
- Peptide Label:	isoform X1
- UniProtKB:	A0A287CWW4 (UniProtKB/TrEMBL), A0A287D2G6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040138593 ⟸ XM_040282659
- Peptide Label:	isoform X3
- UniProtKB:	A0A287D2G6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040138590 ⟸ XM_040282656
- Peptide Label:	isoform X2
- UniProtKB:	I3M055 (UniProtKB/TrEMBL), A0A287D2G6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000027705 ⟸ ENSSTOT00000042049

RefSeq Acc Id:

ENSSTOP00000031479 ⟸ ENSSTOT00000041134

RefSeq Acc Id:

ENSSTOP00000025820 ⟸ ENSSTOT00000033254

RefSeq Acc Id:

ENSSTOP00000002054 ⟸ ENSSTOT00000002297

RefSeq Acc Id:

ENSSTOP00000027385 ⟸ ENSSTOT00000032326

Protein Domains

AGC-kinase C-terminal Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000002290	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000002297.3	UniProtKB/TrEMBL
	ENSSTOT00000032326.1	UniProtKB/TrEMBL
	ENSSTOT00000033254.1	UniProtKB/TrEMBL
	ENSSTOT00000041134.1	UniProtKB/TrEMBL
	ENSSTOT00000042049.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	AGC-kinase_C	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Pkinase_C	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ribosomal_S6_kinase_II	UniProtKB/TrEMBL
	RSK_N	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
NCBI Gene	Rps6ka6	ENTREZGENE
PANTHER	RIBOSOMAL PROTEIN S6 KINASE	UniProtKB/TrEMBL
	RIBOSOMAL PROTEIN S6 KINASE ALPHA-6	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
	Pkinase_C	UniProtKB/TrEMBL
PIRSF	Ribsml_S6_kin_2	UniProtKB/TrEMBL
PROSITE	AGC_KINASE_CTER	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	S_TK_X	UniProtKB/TrEMBL
	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A287CWW4	ENTREZGENE, UniProtKB/TrEMBL
	A0A287D2G6	ENTREZGENE, UniProtKB/TrEMBL
	A0A287DD71_ICTTR	UniProtKB/TrEMBL
	I3M055	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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