Hk1 (hexokinase 1) - Rat Genome Database

Name: Hk1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Hk1 (hexokinase 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Hk1

Name:

hexokinase 1

RGD ID:

12637026

Description:

ENCODES a protein that exhibits ATP binding (ortholog); glucokinase activity (ortholog); glucose binding (ortholog); INVOLVED IN carbohydrate phosphorylation (ortholog); fructose 6-phosphate metabolic process (ortholog); glycolytic process (ortholog); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; fructose and mannose metabolic pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); anemia (ortholog); Animal Disease Models (ortholog); FOUND IN caveola (ortholog); cytosol (ortholog); mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

hexokinase-1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HK1 (hexokinase 1)	NCBI	Ortholog
Mus musculus (house mouse):	Hk1 (hexokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Hk1 (hexokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hk1 (hexokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HK1 (hexokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HK1 (hexokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HK1 (hexokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HK1 (hexokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hk1 (hexokinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	60,574,470 - 60,681,207 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	9,066,999 - 9,159,793 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	9,067,062 - 9,139,112 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute lymphoblastic leukemia (ISO)

anemia (ISO)

Animal Disease Models (ISO)

autism spectrum disorder (ISO)

Charcot-Marie-Tooth disease type 4G (ISO)

Chronic Intermittent Hypoxia (ISO)

colorectal cancer (ISO)

congenital nonspherocytic hemolytic anemia (ISO)

COVID-19 (ISO)

epilepsy (ISO)

Experimental Diabetes Mellitus (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

Hexokinase Deficiency Hemolytic Anemia (ISO)

lung adenocarcinoma (ISO)

macular degeneration (ISO)

multiple myeloma (ISO)

Myocardial Ischemia (ISO)

NEURODEVELOPMENTAL DISORDER WITH VISUAL DEFECTS AND BRAIN ANOMALIES (ISO)

Neurodevelopmental Disorders (ISO)

Nonspherocytic Hemolytic Anemia, due to Hexokinase Deficiency (ISO)

obesity (ISO)

pulmonary hypertension (ISO)

retinitis (ISO)

retinitis pigmentosa (ISO)

Retinitis Pigmentosa 79 (ISO)

sickle cell anemia (ISO)

type 2 diabetes mellitus (ISO)

urinary bladder cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

canonical glycolysis (IEA)

carbohydrate phosphorylation (IEA,ISO)

establishment of protein localization to mitochondrion (IEA)

fructose 6-phosphate metabolic process (ISO)

glucose 6-phosphate metabolic process (IEA)

glucose metabolic process (IEA)

glycolytic process (IEA,ISO)

hexose metabolic process (IEA)

inflammatory response (IEA)

innate immune response (IEA)

intracellular glucose homeostasis (IEA)

maintenance of protein location in mitochondrion (IEA)

mannose metabolic process (ISO)

negative regulation of apoptotic process (ISO)

peptidyl-serine phosphorylation (ISO)

peptidyl-threonine phosphorylation (ISO)

peptidyl-tyrosine phosphorylation (ISO)

positive regulation of cytokine production involved in immune response (IEA)

positive regulation of interleukin-1 beta production (IEA)

protein autophosphorylation (ISO)

protein phosphorylation (ISO)

regulation of anion channel activity (ISO)

response to brassinosteroid (ISO)

response to hypoxia (ISO)

response to ischemia (ISO)

response to ketamine (ISO)

Cellular Component

caveola (ISO)

cytosol (IEA,ISO)

membrane raft (IEA)

mitochondrial outer membrane (IEA)

mitochondrion (IEA,ISO)

protein-containing complex (ISO)

Molecular Function

ATP binding (IEA,ISO)

fructokinase activity (IEA)

glucokinase activity (IEA,ISO)

glucosamine kinase activity (IEA)

glucose binding (IEA,ISO)

hexokinase activity (IEA,ISO)

identical protein binding (ISO)

kinase activity (IEA)

mannokinase activity (IEA)

peptidoglycan binding (IEA)

protein binding (ISO)

protein kinase activity (ISO)

protein-containing complex binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

amino sugar metabolic pathway (ISO)

french type sialuria pathway (ISO)

fructose and mannose metabolic pathway (ISO)

fructosuria pathway (ISO)

galactose metabolic pathway (ISO)

galactosemia pathway (ISO)

glycolysis pathway (ISO)

hereditary fructose intolerance syndrome pathway (ISO)

hypoxia inducible factor pathway (ISO)

sialic acid storage disease pathway (ISO)

Tay-Sachs disease pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Hk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	60,574,470 - 60,681,207 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	9,066,999 - 9,159,793 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	9,067,062 - 9,139,112 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	69,270,000 - 69,401,882 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	69,269,984 - 69,401,884 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	71,029,756 - 71,161,638 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	70,699,762 - 70,831,641 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	70,748,628 - 70,831,641	NCBI
Celera	10	64,305,609 - 64,438,051 (+)	NCBI		Celera
Cytogenetic Map	10	q22.1	NCBI
HuRef	10	65,029,590 - 65,161,554 (+)	NCBI		HuRef
CHM1_1	10	71,311,204 - 71,443,383 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	70,138,041 - 70,269,925 (+)	NCBI		T2T-CHM13v2.0

Hk1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	62,104,634 - 62,215,699 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	62,104,634 - 62,215,687 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	62,268,855 - 62,379,920 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	62,268,855 - 62,379,908 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	61,731,603 - 61,842,656 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	61,665,219 - 61,775,240 (-)	NCBI		MGSCv36	mm8
Celera	10	63,372,104 - 63,483,135 (-)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	32.37	NCBI

Hk1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	30,773,222 - 30,874,814 (-)	NCBI		GRCr8
mRatBN7.2	20	30,230,488 - 30,332,099 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	30,230,486 - 30,332,131 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	31,241,422 - 31,343,013 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	30,632,326 - 30,733,917 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	31,368,974 - 31,470,744 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	31,911,460 - 31,979,780 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	31,912,262 - 31,956,649 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	33,703,472 - 33,770,598 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	20	31,652,769 - 31,721,279 (-)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

Hk1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	21,731,584 - 21,816,324 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	21,733,314 - 21,824,303 (-)	NCBI	ChiLan1.0	ChiLan1.0

HK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	81,415,804 - 81,549,666 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	81,421,126 - 81,554,987 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	65,786,940 - 65,870,204 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	68,289,288 - 68,401,045 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	68,289,288 - 68,401,045 (+)	Ensembl	panpan1.1		panPan2

HK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	20,396,761 - 20,516,889 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	20,421,526 - 20,518,211 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	20,527,050 - 20,646,926 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	20,668,689 - 20,788,765 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	20,668,656 - 20,789,520 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	20,569,179 - 20,688,937 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	20,773,025 - 20,892,822 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	21,116,100 - 21,236,182 (+)	NCBI		UU_Cfam_GSD_1.0

HK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	72,351,246 - 72,460,924 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	72,383,328 - 72,460,927 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	78,486,933 - 78,521,251 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HK1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	61,917,501 - 62,029,737 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	61,917,440 - 62,001,843 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	22,657,626 - 22,744,799 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hk1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	3,591,090 - 3,659,760 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	3,594,478 - 3,656,231 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005325959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040273244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040273245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040273246	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040273248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000029461 ⟹ ENSSTOP00000016178

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936521	9,067,946 - 9,142,037 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000035969 ⟹ ENSSTOP00000032607

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936521	9,067,946 - 9,159,793 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000037114 ⟹ ENSSTOP00000027784

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936521	9,097,546 - 9,142,037 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000039976 ⟹ ENSSTOP00000026834

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936521	9,066,999 - 9,139,783 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000040627 ⟹ ENSSTOP00000028876

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936521	9,096,963 - 9,125,544 (-)	Ensembl

RefSeq Acc Id:

XM_005325959 ⟹ XP_005326016

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	60,574,470 - 60,646,379 (-)	NCBI
SpeTri2.0	NW_004936521	9,067,062 - 9,139,112 (-)	NCBI

Sequence:

show sequence

CCGCGGGAGGAGGAGGAGCCGCCGCGCCGCCGCCGGAGGACCACTGCTCACCCCGGCTGCGGAG
GACCCACCGGCCGCACGCCTGCCGCTCCGCGCCTGCCGCCCCGCGCCCCAGACCGCCAGCATGA
TCGCCGCGCAGCTCCTGGCCTATTACTTCACCGAGCTGAAAGATGACCAAGTCAAAAAGATTGA
TAAGTATCTCTATACCATGCGGCTCTCCGATGAAACTCTGATAGATATCATGACACGCTTCAGG
AAGGAAATGAAGAATGGCCTCTCCCGGGATTTTAATCCAACAGCCACGGTCAAGATGTTGCCAA
CCTTTGTAAGGTCCATTCCTGATGGTTCAGAAAAAGGAGATTTCATCGCCCTGGATCTTGGTGG
GTCTTCCTTTCGAATTCTGCGGGTGCAAGTGAATCATGAGAAAAAACAGAACGTTCACATGGAG
TCCGAGGCTTATGACACCCCGGAGAGCATCGTGCACGGCAGTGGAAGCCAGCTTTTCGATCATG
TTGCCGAGTGCCTGGGAGACTTCATGGAGAAGAAGAAGATTAAGGACAAGAACTTACCCGTGGG
GTTCACGTTTTCTTTCCCTTGCCGGCAATCCAAGATAGACGAGGCCATCCTGATCACCTGGACC
AAGCGGTTTAAAGCCAGTGGCGTGGAGGGGGCAGATGTCGTCAAGCTGCTGAACAAAGCCATCA
AAAAGCGAGGGGACTACGACGCGAACATTGTGGCTGTGGTGAACGACACGGTGGGGACCATGAT
GACCTGTGGCTATGACGACCAGCAGTGTGAAGTCGGCCTGATCATTGGCACGGGCACCAACGCT
TGCTACATGGAGGAACTGAGGCACATTGATCTGGTGGAAGGAGACGAGGGGAGGATGTGCATCA
ACACTGAATGGGGAGCCTTTGGGGACGATGGATCACTGGAAGACATCCGGACCGAGTTTGACAG
AGAGTTAGACCGAGGGTCCCTCAACCCTGGAAAACAGCTGTTTGAGAAGATGGTCAGTGGCATG
TACTTGGGGGAGCTGGTCCGACTGATCCTGGTCAAGATGGCCAAGGAGGGCCTCTTGTTTGAAG
GGCGGATCACCCCGGAGCTGCTCACCAGGGGCAAGTTTAACACCAGTGACGTGTCCGCCATCGA
AAAGAATAAGGAAGGCCTCCACAATGCCAAAGAGATCCTCACCCGCCTGGGCGTGGAGCCATCT
GACGACGACTGTGTCTCGGTCCAGCACGTGTGCACCATCGTGTCCTTCCGCTCGGCCAACCTGG
TGGCTGCCACACTGGGTGCCATCCTGAACCGCCTGCGTGATAACAAGGGGACCCCCAGGCTGCG
GACCACGGTCGGTGTGGACGGCTCTCTGTACAAGACGCACCCGCAGTATTCTCGGCGTTTCCAC
AAGACCCTGAGGCGCCTGGTGCCCGACTCCGACGTTCGTTTCCTCCTCTCGGAGAGCGGCAGTG
GCAAGGGGGCCGCCATGGTGACCGCCGTGGCCTACCGCTTGGCCGAGCAGCACCGGCAGATAGA
GGAGACCCTCGCCCACTTCCGCCTCACCAAGGAGATGCTGCTGGAGGTGAAGAGGAGGATGCGG
ACCGAGATGGAGATGGGGCTGAGGAAGCAGACAAATGACAAGGCTGTGGTCAAGATGCTCCCCT
CCTTTGTCCGGAGCACCCCAGATGGGACCGAGCATGGTGACTTCTTGGCCTTGGATCTTGGAGG
AACGAATTTCCGTGTCCTGCTGGTGAAAATTCGTAGTGGGAAAAAGAGAACAGTGGAAATGCAC
AATAAAATCTATGCCATTCCTCTTGAGATCATGCAAGGCACTGGGGAAGAGCTGTTTGACCACA
TCGTCTCCTGCATCTCTGACTTCCTGGACTACATGGGCATCAAAGGCCCCCGGATGCCTCTGGG
CTTCACCTTCTCATTTCCTTGCAAGCAGACGAGTCTGGATGCGGGAATCCTGATCACCTGGACA
AAGGGTTTTAAGGCAACTGACTGTGTGGGTCACAATGTTGCCACTTTACTAAAGGATGCGATAA
AAAGGAGAGAGGAATTCGACCTGGATGTGGTGGCTATGGTCAACGACACGGTGGGCACCATGAT
GACGTGTGCTTATGAGGAACCCAGCTGTGAGGTTGGACTTATTGTAGGGACTGGCTGTAATGCC
TGCTACATGGAGGAAATGAGGAATGTCGAGATGTTGGAGGGGACTGAAGGGCGAATGTGCATCA
ACATGGAGTGGGGTGCCTTTGGCGACAACGGGAGTCTGGATGATATTAGGACAGAGTATGACAG
ATTGGTGGATGAATACTCTCTAAATGCTGGAAAACAAAGGTATGAGAAGATGATTAGTGGTATG
TACCTGGGTGAAATTGTCCGCAACATCTTGATCGACTTCACCAAGAAGGGATTCCTCTTCCGAG
GGCAGATCTCTGAGCCACTGAAGACCAGGGGCATCTTTGAGACCAAATATCTCTCTCAGATTGA
GAGTGACCGGTTAGCGCTGCTCCAGGTCCGGGCCATCCTCCAGCAGCTGGGTCTGAACAGCACG
TGCGACGACAGTATCCTGGTCAAGACGGTGTGCGGGGTGGTGTCCAAGAGGGCTGCGCAGCTGT
GCGGGGCTGGCATGGCGGCCGTGGTGGACAAGATCCGGGAGAACAGAGGGCTGGACCATCTGAA
CGTGACGGTGGGCGTGGATGGGACACTCTACAAGCTGCATCCGCACTTCTCCAGAATCATGCAC
CAAACGGTGAAGGAACTGTCACCAAAGTGTAATGTGTCCTTCCTCCTGTCTGAAGACGGCAGTG
GCAAGGGGGCTGCCCTCATCACAGCTGTGGGCGTGAGGCTCCGGGGAGAAATGAGCTAAGGGCA
CAGGCCCCCGCCCGCTGCCCGTCCAGCACTTGTCTCTCAAAGCGACGACCCCCCTGTTCCTCTC
AGCGAGCCGCGCTGGGAGCCCTCAGCGCCAGAGCCACCCCCCGCAGCGGGGAAGGAAAGCAATC
CAACGAATGGCGCCTATCGTAGGGTACAACCTAGAGCGTGTGCTGTTGACCATCTCTCACTTGG
ACCCTCACCTGCCCCGCCACTCTGCATGATTTGATCTCCACCTGGTCGTGCATCCCCTCGTGTG
AAGTGTAGCCGCACCCCTTCCTCCCGCGGGCGCCCATCCAGCTCAGATGAAAAGTCGCACCATC
AGACGGGCCCTGTGGCCTCCAAAGCCCGTCCTCGGGGTTGCCTCCCCTGCGTGAAGTGGATTAT
CACCAGCAGTCACTGCCGGACTCTTCCCCCGGGCCCGGGGCCCAGCTTGAAGGGCGAGTGTGGA
CGCAGCGTGACCGCTATCTCCCGTCCCCGCCACCCACTGTGGCAGCCTGGCGGTCCCATCGGGG
GATGTGTCGATGCCACTAGACATGTGTGTGTCCATGGAACCGGTCCTAGCCGCACTGTGACAGT
CTTGCATTCTGTTGATCTCGTGGGGGGGGAGGTGGGAAGTCCCGTGGGAAAGTGTCTTGTCTCC
ATTTGGGTAAAAGGAACCGACCCACAAGCAGCGCCATCACTGGAATTTCCCATCGCTTTTGTGA
GCCATGTTGTATGACCTAGTAAACTTTGTACCAATTCAAAAAGCCGAGTGATGCTTGGTGGCTG
GGGAGAGGGGGGGAGACCTGGGGGTGTGGCAAAAGCCAGATGCTGGGGGATATTTGTGACTGTC
TGGGTGGGCCAAGAGTCTAAAATAAAGATCACGGTCTTTGGCGCCCA

hide sequence

RefSeq Acc Id:

XM_040273244 ⟹ XP_040129178

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	60,574,470 - 60,681,207 (-)	NCBI

RefSeq Acc Id:

XM_040273245 ⟹ XP_040129179

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	60,574,470 - 60,676,616 (-)	NCBI

RefSeq Acc Id:

XM_040273246 ⟹ XP_040129180

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	60,574,470 - 60,649,268 (-)	NCBI

RefSeq Acc Id:

XM_040273248 ⟹ XP_040129182

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	60,574,470 - 60,646,051 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005326016	(Get FASTA)	NCBI Sequence Viewer
	XP_040129178	(Get FASTA)	NCBI Sequence Viewer
	XP_040129179	(Get FASTA)	NCBI Sequence Viewer
	XP_040129180	(Get FASTA)	NCBI Sequence Viewer
	XP_040129182	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000016178.2
	ENSSTOP00000026834.1
	ENSSTOP00000027784.1
	ENSSTOP00000028876.1
	ENSSTOP00000032607.1
GenBank Protein	KAG3264786	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005326016 ⟸ XM_005325959
- Peptide Label:	isoform X1
- UniProtKB:	A0A287D014 (UniProtKB/TrEMBL), I3MVN3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIAAQLLAYYFTELKDDQVKKIDKYLYTMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKML PTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKKQNVHMESEAYDTPESIVHGSGSQLFD HVAECLGDFMEKKKIKDKNLPVGFTFSFPCRQSKIDEAILITWTKRFKASGVEGADVVKLLNKA IKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMC INTEWGAFGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLF EGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSAN LVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESG SGKGAAMVTAVAYRLAEQHRQIEETLAHFRLTKEMLLEVKRRMRTEMEMGLRKQTNDKAVVKML PSFVRSTPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPLEIMQGTGEELFD HIVSCISDFLDYMGIKGPRMPLGFTFSFPCKQTSLDAGILITWTKGFKATDCVGHNVATLLKDA IKRREEFDLDVVAMVNDTVGTMMTCAYEEPSCEVGLIVGTGCNACYMEEMRNVEMLEGTEGRMC INMEWGAFGDNGSLDDIRTEYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLF RGQISEPLKTRGIFETKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQ LCGAGMAAVVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDG SGKGAALITAVGVRLRGEMS hide sequence

RefSeq Acc Id:	XP_040129178 ⟸ XM_040273244
- Peptide Label:	isoform X2
- UniProtKB:	A0A287DGH0 (UniProtKB/TrEMBL), I3MVN3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040129179 ⟸ XM_040273245
- Peptide Label:	isoform X2
- UniProtKB:	A0A287DGH0 (UniProtKB/TrEMBL), I3MVN3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040129180 ⟸ XM_040273246
- Peptide Label:	isoform X3
- UniProtKB:	I3MVN3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040129182 ⟸ XM_040273248
- Peptide Label:	isoform X3
- UniProtKB:	I3MVN3 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000016178 ⟸ ENSSTOT00000029461

RefSeq Acc Id:

ENSSTOP00000028876 ⟸ ENSSTOT00000040627

RefSeq Acc Id:

ENSSTOP00000027784 ⟸ ENSSTOT00000037114

RefSeq Acc Id:

ENSSTOP00000032607 ⟸ ENSSTOT00000035969

RefSeq Acc Id:

ENSSTOP00000026834 ⟸ ENSSTOT00000039976

Protein Domains

Hexokinase C-terminal Hexokinase N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000023877	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000029461.2	UniProtKB/TrEMBL
	ENSSTOT00000035969.1	UniProtKB/TrEMBL
	ENSSTOT00000037114.1	UniProtKB/TrEMBL
	ENSSTOT00000039976.1	UniProtKB/TrEMBL
	ENSSTOT00000040627.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.420.40	UniProtKB/TrEMBL
	3.40.367.20	UniProtKB/TrEMBL
InterPro	ATPase_NBD	UniProtKB/TrEMBL
	Hexokinase	UniProtKB/TrEMBL
	Hexokinase_BS	UniProtKB/TrEMBL
	Hexokinase_C	UniProtKB/TrEMBL
	Hexokinase_N	UniProtKB/TrEMBL
NCBI Gene	Hk1	ENTREZGENE
PANTHER	HEXOKINASE-1	UniProtKB/TrEMBL
	PTHR19443	UniProtKB/TrEMBL
Pfam	Hexokinase_1	UniProtKB/TrEMBL
	Hexokinase_2	UniProtKB/TrEMBL
PRINTS	HEXOKINASE	UniProtKB/TrEMBL
PROSITE	HEXOKINASE_1	UniProtKB/TrEMBL
	HEXOKINASE_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53067	UniProtKB/TrEMBL
UniProt	A0A287D014	ENTREZGENE, UniProtKB/TrEMBL
	A0A287D2M8_ICTTR	UniProtKB/TrEMBL
	A0A287D5L1_ICTTR	UniProtKB/TrEMBL
	A0A287DGH0	ENTREZGENE, UniProtKB/TrEMBL
	I3MVN3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)