Liph (lipase H) - Rat Genome Database

Name: Liph
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Liph (lipase H) Ictidomys tridecemlineatus

Analyze

Symbol:

Liph

Name:

lipase H

RGD ID:

12625996

Description:

ENCODES a protein that exhibits carboxylic ester hydrolase activity (inferred); heparin binding (inferred); lipase activity (inferred); INVOLVED IN lipid catabolic process (inferred); lipid metabolic process (inferred); ASSOCIATED WITH Currarino syndrome (ortholog); familial woolly hair syndrome (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lipase member H

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LIPH (lipase H)	NCBI	Ortholog
Mus musculus (house mouse):	Liph (lipase, member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Liph (lipase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Liph (lipase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LIPH (lipase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LIPH (lipase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LIPH (lipase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LIPH (lipase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Liph (lipase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	118,212,626 - 118,255,245 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936578	4,320,937 - 4,345,972 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936578	4,304,503 - 4,346,838 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Currarino syndrome (ISO)

familial woolly hair syndrome (ISO)

genetic disease (ISO)

hypotrichosis (ISO)

hypotrichosis 1 (ISO)

hypotrichosis 7 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid catabolic process (IEA)

lipid metabolic process (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA)

plasma membrane (IEA)

Molecular Function

carboxylic ester hydrolase activity (IEA)

heparin binding (IEA)

lipase activity (IEA)

metal ion binding (IEA)

phospholipase activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Liph
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	118,212,626 - 118,255,245 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936578	4,320,937 - 4,345,972 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936578	4,304,503 - 4,346,838 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LIPH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	185,506,262 - 185,552,588 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	185,506,262 - 185,552,588 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	185,224,050 - 185,270,376 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	186,708,264 - 186,753,063 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	186,708,294 - 186,753,043	NCBI
Celera	3	183,671,086 - 183,716,608 (-)	NCBI		Celera
Cytogenetic Map	3	q27.2	NCBI
HuRef	3	182,635,165 - 182,680,037 (-)	NCBI		HuRef
CHM1_1	3	185,188,581 - 185,233,458 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	188,322,024 - 188,368,409 (-)	NCBI		T2T-CHM13v2.0

Liph
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	21,772,567 - 21,814,408 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	21,772,567 - 21,814,413 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	21,953,817 - 21,995,658 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	21,953,817 - 21,995,663 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	21,953,890 - 21,995,615 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	21,868,054 - 21,910,794 (-)	NCBI		MGSCv36	mm8
Celera	16	22,520,630 - 22,562,761 (-)	NCBI		Celera
Cytogenetic Map	16	B1	NCBI
cM Map	16	12.95	NCBI

Liph
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	92,536,724 - 92,586,117 (+)	NCBI		GRCr8
mRatBN7.2	11	79,032,229 - 79,081,625 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	79,033,312 - 79,081,625 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	87,767,801 - 87,815,562 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	80,421,447 - 80,469,206 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	79,482,142 - 79,529,905 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	82,680,167 - 82,732,145 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	11	85,808,222 - 85,815,457 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	11	85,770,270 - 85,788,987 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	11	77,895,628 - 77,940,437 (+)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

Liph
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	22,014,961 - 22,052,203 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	22,015,254 - 22,049,508 (+)	NCBI	ChiLan1.0	ChiLan1.0

LIPH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	183,383,292 - 183,426,940 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	183,388,009 - 183,431,657 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	182,541,666 - 182,586,175 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	191,018,172 - 191,062,502 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	191,018,178 - 191,062,502 (-)	Ensembl	panpan1.1		panPan2

LIPH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	18,269,510 - 18,316,664 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	18,270,070 - 18,316,066 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	22,345,759 - 22,402,330 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	18,169,626 - 18,226,433 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	18,178,666 - 18,225,876 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	18,205,295 - 18,261,851 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	18,201,211 - 18,258,007 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	18,431,011 - 18,487,467 (-)	NCBI		UU_Cfam_GSD_1.0

LIPH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	123,371,860 - 123,419,434 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	123,372,909 - 123,419,505 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	132,915,031 - 132,957,520 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LIPH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	3,872,492 - 3,922,231 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	3,873,166 - 3,921,209 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	12,629,696 - 12,685,571 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Liph
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	71,109,665 - 71,145,985 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	71,110,219 - 71,149,197 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005331021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000011248 ⟹ ENSSTOP00000010089

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936578	4,320,937 - 4,345,972 (+)	Ensembl

RefSeq Acc Id:

XM_005331021 ⟹ XP_005331078

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	118,212,626 - 118,255,245 (+)	NCBI
SpeTri2.0	NW_004936578	4,304,503 - 4,346,838 (+)	NCBI

Sequence:

show sequence

AAACCCCGAAGTGAAAATTCTAAGGCTCTGCGAAGTAAATTATCCTTCTGTGAATGTGACCCAA
GCTCTCTGCAGTTCCATATGCTGAGGTTATTCTTACTTATCAGTTTGACGTGCTTGGTGAGATC
AGACGCAGCTGAAACATGCCCTTCATTCACCAGACTGAGCTTTCACAGTGCGGTGGTGGGTACT
GGGCTGCAGGTGAGGCTGATGCTCTATACGAAGAGAAACCAGACCTGCGCACAAATCATCAACT
CAACAGCTTTGGGGAACTTGAATGTGACCAAGAAAACCACCTTCATTATTCATGGATTCCGGCC
AACAGGTTCCGCTCCAGTTTGGATGGGAGACTTAGTAGAGGCTTTGCTCTCTGCAGAACACATG
AACGTGGTTGTTGTTGATTGGAATCGAGGAGCTACCACTGTCATATACACCCACGCCGCTAATA
AGACCAAAAAAGTAGCCATCATCTTGAAGGAATTTATCGACCAGATGTTGGCAGAAGGAGCTTC
TCTTGACAACATTTATATGATTGGAGTAAGTCTAGGAGCCCACATATCTGGATTTGTTGGAGAA
ATGTATGATGGGCAGTTGGGGAGAATTACAGGTCTCGATCCTGCGGGCCCTTTATTCAACGGGA
GGCCCCCCCAGGACAGATTAGATCCCAGCGATGCGCAGTTCGTTGATGTCATCCACTCCGACAC
TGATGCACTGGGCTACAAGGAACCGCTAGGAAACATAGACTTCTATCCAAATGGAGGATTGGAT
CAACCTGGTTGCCCCCAAACGATATTTGGAGGAATAAAGTATTTCAAGTGTGACCACCAGAGGT
CCGTGTACCTGTACCTGGCTTCCCTGAGAGAGGACTGTGAGATCACCGCCTATCCCTGTGACTC
CTACAGGGACTACAGGAACGGCAAGTGCACCAGCTGCGGCACACCAGAGCAGTCCTGTCCTGTC
CTGGGCTATTATGCTGACAATTGGAAAGACTACTTAAAGCAGAAAGATCCTCCGATGACTAAGG
CGTTCTTTGACACAGCTGAGAAGGAGCCATTCTGCATGTATCATTACTTTGTGGACATTATATC
TTGGAACAAGAACATCAGAAGAGGGTCTATTACAATCAAATTGAGAGACAGAGATGGAAATACC
ACAGAATCTAAAATCGATCATGAACCAGCCACATTTCAGAAATATCATCAAGTGAGCCTGCTTG
CAAGATTTAATCAAGATCTGGACAAAGTAGCAACAATTTCCTTGGTGTTCTCTACAGGATCTGT
AGTAGGTCCTAAGTACAAGCTCAGGATCCTCCGAATTAGGTTGAGGTCCCTTGTCCATCCAGAG
AGGCCCCAGTTATGTCGGTATGATCTTGTCCTGATGGAAAATGTCCAGACAGTCTTCAAACCTA
TTCTCTGCCCCAAGTTGCAAATGTAACTGCTGCTGCTGGGGACAGGTGGGCAGCAACGATGTCA
GGAAAGCTGCATCTACGGCCTCTTTTAAAGCTTCACCTGAGCTTTTCCTCAAAGCTCAAAAAGC
ATGAAAAAAACCAAGGTTATTTTCAGCAGCGTCCTACAGATGTCACATTGCAGAACGTCAAACG
ACCTTGTGATTATAAAACGATCCTGGGAAGGGTGGCCCTAACTAGGGCAAGTCAGAAATAGCCA
GCCTTCTGACAGCCCAGTGCTTTGTCTGGCTGCATCCTGGGGCCTGTTTGTTCCGACCTGTCGA
TTCTGCTGCCCATCACACAGGCTCTTTGTTCCTCAGGGCTTCGGGTACTCATCTTAAGGCTAGG
TGGGGGGCTGGAGACCTCACTCTGGACTTTCTGTTCCCTGTGCCGAATTCTGCACAGAACCCAT
CACGCAGAAGGGAACAAAACTGACCTACCTCTCAGGGCTGCCGTGTGGGTATGGAAGACAAGTC
TATGAAGGGTTCTTTGAAATCCTCTGGGTACCACATCTGTGAAGGTGTCATGAATGTGAATATG
TTGTTATTTATTTTAACGTGGCTTAGCTCGTATCCTTTGATCATATCCTTTGATAGGGGTGGCC
CCTCCTTATCAATACAGCTTCTCTCTGGGGCAGCAAGAAAGCCACATACCCCTGTCCCACCCCC
TCTGAAGTGATGCTGGTGCAAAGGAGGTAGAGATGGGCTGGTAGCCTGAGGGCAGTGCTGGGAC
TAGGGAGGAAGCAGCAGCCTCACACCCCTGGGACAGGGGACCAGCAGGGGAGGAAAGGGCTTGT
TTTTCACCTAAGATGGAGAAGGATCATTTTATAGGCAACCCTTCTCTTTTTTTATATATT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005331078	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000010089.3
GenBank Protein	KAG3271149	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005331078 ⟸ XM_005331021

- UniProtKB:

I3MGY6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLRLFLLISLTCLVRSDAAETCPSFTRLSFHSAVVGTGLQVRLMLYTKRNQTCAQIINSTALGN
LNVTKKTTFIIHGFRPTGSAPVWMGDLVEALLSAEHMNVVVVDWNRGATTVIYTHAANKTKKVA
IILKEFIDQMLAEGASLDNIYMIGVSLGAHISGFVGEMYDGQLGRITGLDPAGPLFNGRPPQDR
LDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNGGLDQPGCPQTIFGGIKYFKCDHQRSVYLYL
ASLREDCEITAYPCDSYRDYRNGKCTSCGTPEQSCPVLGYYADNWKDYLKQKDPPMTKAFFDTA
EKEPFCMYHYFVDIISWNKNIRRGSITIKLRDRDGNTTESKIDHEPATFQKYHQVSLLARFNQD
LDKVATISLVFSTGSVVGPKYKLRILRIRLRSLVHPERPQLCRYDLVLMENVQTVFKPILCPKL
QM

hide sequence

RefSeq Acc Id:

ENSSTOP00000010089 ⟸ ENSSTOT00000011248

Protein Domains

Lipase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000011247	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000011248.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/TrEMBL
	Lipase/vitellogenin	UniProtKB/TrEMBL
	Lipase_LIPH	UniProtKB/TrEMBL
	Lipase_N	UniProtKB/TrEMBL
	TAG_lipase	UniProtKB/TrEMBL
NCBI Gene	Liph	ENTREZGENE
PANTHER	LIPASE MEMBER H	UniProtKB/TrEMBL
	PTHR11610	UniProtKB/TrEMBL
Pfam	Lipase	UniProtKB/TrEMBL
PIRSF	Lipoprotein_lipase_LIPH	UniProtKB/TrEMBL
PRINTS	TAGLIPASE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53474	UniProtKB/TrEMBL
UniProt	I3MGY6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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