Plekha1 (pleckstrin homology domain containing A1) - Rat Genome Database

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Gene: Plekha1 (pleckstrin homology domain containing A1) Ictidomys tridecemlineatus
Analyze
Symbol: Plekha1
Name: pleckstrin homology domain containing A1
RGD ID: 12620041
Description: ENCODES a protein that exhibits PDZ domain binding (ortholog); phosphatidylinositol-3,4-bisphosphate binding (ortholog); INVOLVED IN androgen metabolic process (ortholog); B cell receptor signaling pathway (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH COVID-19 (ortholog); craniosynostosis (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain-containing family A member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721314,322,684 - 14,377,443 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648611,203,873 - 11,241,028 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Plekha1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721314,322,684 - 14,377,443 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648611,203,873 - 11,241,028 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810122,374,708 - 122,442,600 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10122,374,696 - 122,432,354 (+)EnsemblGRCh38hg38GRCh38
GRCh3710124,134,224 - 124,202,116 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610124,124,210 - 124,181,856 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410124,141,832 - 124,181,856NCBI
Celera10117,866,583 - 117,924,124 (+)NCBICelera
Cytogenetic Map10q26.13NCBI
HuRef10117,764,924 - 117,822,671 (+)NCBIHuRef
CHM1_110124,418,717 - 124,476,463 (+)NCBICHM1_1
T2T-CHM13v2.010123,270,978 - 123,338,841 (+)NCBIT2T-CHM13v2.0
Plekha1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397130,462,281 - 130,515,224 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7130,467,486 - 130,515,042 (+)EnsemblGRCm39 Ensembl
GRCm387130,860,551 - 130,913,494 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7130,865,756 - 130,913,312 (+)EnsemblGRCm38mm10GRCm38
MGSCv377138,009,424 - 138,056,816 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367130,657,058 - 130,704,450 (+)NCBIMGSCv36mm8
Celera7130,676,697 - 130,724,178 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map773.19NCBI
Plekha1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81194,858,239 - 194,909,418 (+)NCBIGRCr8
mRatBN7.21185,427,982 - 185,479,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1185,428,048 - 185,479,156 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1193,778,280 - 193,829,384 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01200,956,894 - 201,007,940 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01193,628,667 - 193,679,713 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01201,429,716 - 201,481,411 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1201,429,771 - 201,480,877 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01208,462,186 - 208,513,824 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41190,187,202 - 190,238,309 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1183,040,481 - 183,091,589 (+)NCBICelera
Cytogenetic Map1q41NCBI
Plekha1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955477659,641 - 732,627 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955477659,640 - 730,394 (+)NCBIChiLan1.0ChiLan1.0
PLEKHA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28134,230,044 - 134,287,769 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110134,235,565 - 134,293,121 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010118,942,896 - 119,001,185 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110122,354,773 - 122,412,588 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10122,354,765 - 122,412,588 (+)Ensemblpanpan1.1panPan2
PLEKHA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12832,025,791 - 32,081,824 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2832,026,350 - 32,081,835 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2832,100,800 - 32,156,873 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02832,561,443 - 32,617,733 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2832,561,576 - 32,617,733 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12832,093,840 - 32,149,960 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02832,115,324 - 32,171,582 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02832,319,773 - 32,376,120 (+)NCBIUU_Cfam_GSD_1.0
PLEKHA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14131,960,939 - 132,016,652 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114131,960,932 - 132,016,664 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214143,414,765 - 143,470,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19115,110,316 - 115,168,113 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9115,128,942 - 115,165,576 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604876,408,461 - 76,466,336 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekha1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473724,299,199 - 24,365,459 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_040272465   ⟹   XP_040128399
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721314,322,684 - 14,377,443 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040128399 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000009140.3
  ENSSTOP00000024042.1
GenBank Protein KAG3263947 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040128399   ⟸   XM_040272465
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010191 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010187.3 UniProtKB/TrEMBL
  ENSSTOT00000031373.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Plekha1 ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 1 UniProtKB/TrEMBL
  TANDEM PH DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A287CRY7_ICTTR UniProtKB/TrEMBL
  I3MF02_ICTTR UniProtKB/TrEMBL