Gna15 (G protein subunit alpha 15)

Gene: Gna15 (G protein subunit alpha 15) Ictidomys tridecemlineatus

Analyze

Symbol:

Gna15

Name:

G protein subunit alpha 15

RGD ID:

12614212

Description:

ENCODES a protein that exhibits G protein-coupled receptor binding (inferred); G-protein beta/gamma-subunit complex binding (inferred); GTP binding (inferred); INVOLVED IN calcium-mediated signaling (ortholog); phospholipase C-activating G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; G protein mediated signaling pathway via Galphaq family; ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN heterotrimeric G-protein complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

guanine nucleotide-binding protein subunit alpha-15

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	216,017,998 - 216,030,469 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	1,804,231 - 1,816,782 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	1,802,576 - 1,816,772 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

action potential (IEA)

adenylate cyclase-modulating G protein-coupled receptor signaling pathway (IEA)

calcium-mediated signaling (IEA,ISO)

G protein-coupled receptor signaling pathway (IEA)

phospholipase C-activating dopamine receptor signaling pathway (IEA)

phospholipase C-activating G protein-coupled receptor signaling pathway (IEA,ISO)

signal transduction (IEA)

Cellular Component

heterotrimeric G-protein complex (IEA)

Molecular Function

G protein-coupled receptor binding (IEA)

G-protein beta/gamma-subunit complex binding (IEA)

GTP binding (IEA)

GTPase activity (IEA)

guanyl nucleotide binding (IEA)

metal ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

eicosanoid signaling pathway (ISO)

endothelin signaling pathway (ISO)

G protein mediated signaling pathway via Galphaq family (ISO)

sphingosine 1-phosphate signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Gna15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	216,017,998 - 216,030,469 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	1,804,231 - 1,816,782 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	1,802,576 - 1,816,772 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GNA15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	3,136,033 - 3,163,749 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	3,136,033 - 3,163,749 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	3,136,031 - 3,163,747 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	3,087,191 - 3,114,766 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	3,087,229 - 3,114,741	NCBI
Celera	19	3,072,520 - 3,100,641 (+)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	2,905,020 - 2,932,757 (+)	NCBI		HuRef
CHM1_1	19	3,136,066 - 3,163,645 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	3,111,823 - 3,140,075 (+)	NCBI		T2T-CHM13v2.0

Gna15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	81,338,147 - 81,360,283 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	81,338,140 - 81,360,059 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	81,502,313 - 81,524,447 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	81,502,306 - 81,524,225 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	80,965,058 - 80,986,970 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	80,905,442 - 80,927,354 (-)	NCBI		MGSCv36	mm8
Celera	10	82,525,696 - 82,547,406 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Gna15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	8,835,396 - 8,856,269 (+)	NCBI		GRCr8
mRatBN7.2	7	8,184,632 - 8,205,508 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	8,184,861 - 8,205,508 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	11,070,892 - 11,091,537 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	12,946,556 - 12,967,020 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	10,813,533 - 10,834,132 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	11,054,249 - 11,075,152 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	11,054,333 - 11,077,251 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	11,221,467 - 11,242,341 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	9,669,956 - 9,689,442 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	9,669,955 - 9,689,442 (+)	NCBI
Celera	7	6,375,600 - 6,396,028 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

Gna15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	5,252,547 - 5,270,894 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	5,254,546 - 5,270,864 (-)	NCBI	ChiLan1.0	ChiLan1.0

GNA15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	7,533,919 - 7,562,117 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	6,766,714 - 6,794,947 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	2,163,773 - 2,191,985 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	3,116,969 - 3,146,118 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	3,116,969 - 3,146,118 (+)	Ensembl	panpan1.1		panPan2

GNA15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	56,117,398 - 56,129,251 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	56,118,067 - 56,126,502 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	55,841,262 - 55,861,721 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	56,776,099 - 56,796,565 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	56,776,384 - 56,795,993 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	55,831,499 - 55,851,940 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	56,315,605 - 56,336,066 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	56,514,343 - 56,534,807 (-)	NCBI		UU_Cfam_GSD_1.0

GNA15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	75,408,724 - 75,433,814 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	75,408,723 - 75,433,809 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	75,928,409 - 75,949,083 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GNA15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	2,901,502 - 2,930,567 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	2,901,762 - 2,932,138 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	5,652,079 - 5,680,809 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gna15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	6,046,186 - 6,063,330 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	6,048,697 - 6,062,851 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005332204	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000027316 ⟹ ENSSTOP00000022484

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936588	1,804,231 - 1,816,782 (+)	Ensembl

RefSeq Acc Id:

XM_005332204 ⟹ XP_005332261

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	216,017,998 - 216,030,469 (-)	NCBI
SpeTri2.0	NW_004936588	1,802,576 - 1,816,772 (+)	NCBI

Sequence:

show sequence

ATGGCTGGGGTCGGTGATGGGCAGGGCCGCCCTCGGCCCGCCTGCACCCATGCCCACTCTGCCA
GCCGTCCCGACTCCCCAGGTCCTGGCGAGAGCGGCAAGAGCACCTTCATCAAGCAGATGCGCAT
CATCCACGGCAACGGCTACTCGGAGGAGGAGCGCCGGGGCTTCCGGCCGCTGGTCTACCAGAAC
ATCTTTGTGTCCATGCAGGCCCTGATCGAGGCCATGGGCAGGCTGCAGATCCCCTTCAGCAGGC
CCGAGAGCGAGCACCACGCCAGCCTGGTCATGAGCCAGGATCCCTACAAGGTGACCGCGTTCGA
GCAGCGCTGTGCGGTGGCCGTGCAGTACTTGTGGCAGGATGCTGGCGTCCAGGCCTGCTATGAG
CGCCGGCGTGAGTTCCACCTGCTGGACTCGGCAGTGTACTACCTGTCCCACCTGGAGCGCATCA
CCGAGGACGGCTACATCCCCACGGCGCAGGACGTCCTGCGGAGCCGCATGCCCACCACTGGCAT
CAACGAGTACTGCTTCTCCGTGCAGAAGACCAAACTGCGGATCGTGGATGTCGGTGGCCAGAAG
TCGGAGCGTAAGAAGTGGATCCACTGCTTCGAGAACGTGATGGCGCTGATCTACCTGGCCTCGC
TGAGCGAGTACGACCAGTGCCTGGAGGAGAACAGCCAGGAGAACCGCATGAAGGAGAGCCTGGC
GCTGTTCGGCACCATCCTGGAGCTGCCCTGGTTCCGGAGCACCTCGGTCATCCTCTTCCTCAAC
AAGACGGACATCCTGGAGGAGAAGATCCCCTCCTCCCACCTGGCCACCTACTTCCCCAGCTTCC
AGGGCCCCCGGCAGGACGCGGAGGCGGCCAAGAGGTTCATCCTGGACATGTACACGGGCATGTA
CGCCAGCTGTGTGGACGGCCCCGAGGGCAGCAAGCGAGGCCCGCGCTCCCGCCGCCTCTTCAGC
CACTACACGTGCGCCACGGACACGCAGAACATCCGCAAGGTCTTCAAGGACGTGCGGGACTCGG
TGCTGGCCCGCTACCTGGACGAGATCAACCTGCTGTGACCACCCCTGGCAGGCGGTGGGCAGTG
GAGATGGACCCCAGATGCCCGTCGCTCCGGCCCAGAGCCAGGAGGCAGAAGGCCCTCATGCGAG
GGACTGGAGGGACGGACGGCCCACCACTGCCCTCTCTCCTCTGCCCCTCGCCTGGTCAGCCGTC
CCCGCCGACCTCCTGGACTCCAGCTACGTCCTTGGAAAGGGAGGAACAACATGGCCTCGGGGGT
GGGGGTGCCAGGGGGGGGAAGGTGAGGCCCTGGTGGGAGGCTGCGTGGGAGGCCTCTGGCCCCG
TCACTGGGTGACTCTGTGAGGGAAAGGAGCCGTCCTTCGGGGTGGGCTCTGGCGCCCTCTGGTG
GAAGCAGGAGGAATCCCCGCAGATGGCGCTCACCCAGGACAGGTGGCCGGTCAGGGGCCTCCCG
GCGGCCACCACAGAGCCCCCTTCCAGAGCCCCAGGCCCACGGCGTCCTGCCCCGGTGTGCAGAG
GAGGAACCCGAGGCCCCAGGTCCCTCTCCTGCTCCAAACAGCCTCTGTATTTATTCCCCGCGTC
CACCGGCCCCCCACGGGGTAGACATTAAAGAAAGCACCTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005332261	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000022484.2
GenBank Protein	KAG3280751	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005332261 ⟸ XM_005332204

- UniProtKB:

I3NDN7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGVGDGQGRPRPACTHAHSASRPDSPGPGESGKSTFIKQMRIIHGNGYSEEERRGFRPLVYQN
IFVSMQALIEAMGRLQIPFSRPESEHHASLVMSQDPYKVTAFEQRCAVAVQYLWQDAGVQACYE
RRREFHLLDSAVYYLSHLERITEDGYIPTAQDVLRSRMPTTGINEYCFSVQKTKLRIVDVGGQK
SERKKWIHCFENVMALIYLASLSEYDQCLEENSQENRMKESLALFGTILELPWFRSTSVILFLN
KTDILEEKIPSSHLATYFPSFQGPRQDAEAAKRFILDMYTGMYASCVDGPEGSKRGPRSRRLFS
HYTCATDTQNIRKVFKDVRDSVLARYLDEINLL

hide sequence

RefSeq Acc Id:

ENSSTOP00000022484 ⟸ ENSSTOT00000027316

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000021930	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000027316.2	UniProtKB/TrEMBL
Gene3D-CATH	1.10.400.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	Gprotein_alpha_Q	UniProtKB/TrEMBL
	Gprotein_alpha_su	UniProtKB/TrEMBL
	GproteinA_insert	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
NCBI Gene	Gna15	ENTREZGENE
PANTHER	GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-15	UniProtKB/TrEMBL
	PTHR10218	UniProtKB/TrEMBL
Pfam	G-alpha	UniProtKB/TrEMBL
PRINTS	GPROTEINA	UniProtKB/TrEMBL
	GPROTEINAQ	UniProtKB/TrEMBL
PROSITE	G_ALPHA	UniProtKB/TrEMBL
SMART	G_alpha	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47895	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	I3NDN7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)