Spg11 (SPG11 vesicle trafficking associated, spatacsin) - Rat Genome Database

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Gene: Spg11 (SPG11 vesicle trafficking associated, spatacsin) Ictidomys tridecemlineatus
Analyze
Symbol: Spg11
Name: SPG11 vesicle trafficking associated, spatacsin
RGD ID: 12613134
Description: ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN autophagosome organization (ortholog); axo-dendritic transport (ortholog); axon extension (ortholog); ASSOCIATED WITH AGAT deficiency (ortholog); amyotrophic lateral sclerosis (ortholog); autism spectrum disorder (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: spastic paraplegia 11 (autosomal recessive); spatacsin; SPG11, spatacsin vesicle trafficking associated; SPG11, spatacsin vesicle trafficking associated, transcript variant X1; SPG11, spatacsin vesicle trafficking associated, transcript variant X2; SPG11, spatacsin vesicle trafficking associated, transcript variant X3; SPG11, spatacsin vesicle trafficking associated, transcript variant X4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864089,693,796 - 89,770,733 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364717,540,647 - 7,618,783 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (ISO)
cytoplasm  (ISO)
cytoplasmic vesicle  (ISO)
cytosol  (ISO)
dendrite  (ISO)
nucleolus  (ISO)
plasma membrane  (ISO)
synapse  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Spg11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864089,693,796 - 89,770,733 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364717,540,647 - 7,618,783 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPG11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381544,562,696 - 44,663,662 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1544,554,818 - 44,663,688 (-)EnsemblGRCh38hg38GRCh38
GRCh371544,854,894 - 44,955,860 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361542,642,186 - 42,743,168 (-)NCBINCBI36Build 36hg18NCBI36
Celera1521,744,647 - 21,845,628 (-)NCBICelera
Cytogenetic Map15q21.1NCBI
HuRef1521,678,554 - 21,779,155 (-)NCBIHuRef
CHM1_11544,972,998 - 45,073,973 (-)NCBICHM1_1
T2T-CHM13v2.01542,370,662 - 42,471,634 (-)NCBIT2T-CHM13v2.0
Spg11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392121,884,001 - 121,949,915 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2121,884,001 - 121,948,867 (-)EnsemblGRCm39 Ensembl
GRCm382122,053,526 - 122,119,434 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2122,053,520 - 122,118,386 (-)EnsemblGRCm38mm10GRCm38
MGSCv372121,879,262 - 121,944,122 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera2155,871,768 - 155,874,475 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.5NCBI
Spg11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83129,453,118 - 129,526,469 (-)NCBIGRCr8
mRatBN7.23109,007,658 - 109,072,904 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3109,008,135 - 109,072,911 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3112,682,104 - 112,746,807 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03121,277,640 - 121,342,332 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03118,938,014 - 119,002,708 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03113,999,600 - 114,064,438 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3113,999,719 - 114,065,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03120,539,553 - 120,604,712 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43108,839,055 - 108,905,008 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3107,906,940 - 107,971,094 (-)NCBICelera
Cytogenetic Map3q35NCBI
Spg11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541611,086,176 - 11,168,332 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541611,084,448 - 11,168,478 (-)NCBIChiLan1.0ChiLan1.0
SPG11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21633,811,472 - 33,912,784 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11537,974,171 - 38,076,040 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01523,519,311 - 23,620,532 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11541,688,081 - 41,788,616 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1541,688,081 - 41,788,616 (-)Ensemblpanpan1.1panPan2
SPG11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13011,233,709 - 11,305,454 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3011,233,718 - 11,305,485 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3011,290,282 - 11,362,060 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03011,370,230 - 11,442,064 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3011,370,232 - 11,442,889 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13011,277,612 - 11,349,334 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03011,400,030 - 11,471,816 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03011,519,270 - 11,591,057 (-)NCBIUU_Cfam_GSD_1.0
SPG11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1126,902,186 - 127,003,397 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1 Ensembl1126,890,892 - 126,899,991 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11126,890,464 - 126,998,014 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SPG11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12638,386,000 - 38,482,236 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048102,561,369 - 102,665,640 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spg11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480411,569,150 - 11,670,373 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480411,569,024 - 11,672,037 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005316508   ⟹   XP_005316565
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864089,693,796 - 89,770,732 (-)NCBI
SpeTri2.0NW_0049364717,541,859 - 7,618,783 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021726459   ⟹   XP_021582134
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864089,693,796 - 89,770,732 (-)NCBI
SpeTri2.0NW_0049364717,540,647 - 7,618,778 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040274924   ⟹   XP_040130858
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864089,693,796 - 89,770,733 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005316565   ⟸   XM_005316508
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021582134   ⟸   XM_021726459
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_040130858   ⟸   XM_040274924
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
NCBI Gene Spg11 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-05 Spg11  SPG11 vesicle trafficking associated, spatacsin    SPG11, spatacsin vesicle trafficking associated  Symbol and/or name change 5135510 APPROVED
2017-02-07 Spg11  SPG11, spatacsin vesicle trafficking associated    spastic paraplegia 11 (autosomal recessive)  Symbol and/or name change 5135510 APPROVED