Kcns2 (potassium voltage-gated channel modifier subfamily S member 2) - Rat Genome Database

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Gene: Kcns2 (potassium voltage-gated channel modifier subfamily S member 2) Ictidomys tridecemlineatus
Analyze
Symbol: Kcns2
Name: potassium voltage-gated channel modifier subfamily S member 2
RGD ID: 12589409
Description: ENCODES a protein that exhibits potassium channel activity (inferred); voltage-gated potassium channel activity (inferred); INVOLVED IN potassium ion transmembrane transport (inferred); potassium ion transport (inferred); protein homooligomerization (inferred); ASSOCIATED WITH Cohen syndrome (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred); monoatomic ion channel complex (inferred); perinuclear region of cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel subfamily S member 2; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530337,028,375 - 37,034,228 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647044,456,526 - 44,460,327 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647044,455,117 - 44,460,193 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcns2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530337,028,375 - 37,034,228 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647044,456,526 - 44,460,327 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647044,455,117 - 44,460,193 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38898,426,958 - 98,432,853 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl898,426,958 - 98,432,853 (+)EnsemblGRCh38hg38GRCh38
GRCh37899,439,186 - 99,445,081 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36899,508,426 - 99,512,201 (+)NCBINCBI36Build 36hg18NCBI36
Celera895,625,108 - 95,628,883 (+)NCBICelera
Cytogenetic Map8q22.2NCBI
HuRef894,643,401 - 94,646,268 (+)NCBIHuRef
CHM1_1899,479,872 - 99,483,647 (+)NCBICHM1_1
T2T-CHM13v2.0899,552,416 - 99,558,311 (+)NCBIT2T-CHM13v2.0
Kcns2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391534,837,501 - 34,843,553 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1534,837,501 - 34,843,553 (+)EnsemblGRCm39 Ensembl
GRCm381534,837,355 - 34,843,407 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1534,837,355 - 34,843,407 (+)EnsemblGRCm38mm10GRCm38
MGSCv371534,767,136 - 34,772,092 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361534,781,970 - 34,786,926 (+)NCBIMGSCv36mm8
Celera1535,465,135 - 35,470,092 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1514.34NCBI
Kcns2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8767,907,492 - 67,913,562 (+)NCBIGRCr8
mRatBN7.2766,022,352 - 66,028,422 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl766,022,352 - 66,028,422 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx767,911,555 - 67,917,625 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0770,113,237 - 70,119,307 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0769,986,815 - 69,992,884 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0773,559,226 - 73,590,385 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl773,588,163 - 73,590,385 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0773,734,435 - 73,765,356 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4770,249,013 - 70,280,172 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1770,298,679 - 70,300,902 (+)NCBI
Celera763,093,318 - 63,124,340 (+)NCBICelera
Cytogenetic Map7q22NCBI
Kcns2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541714,076,521 - 14,077,957 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541714,076,494 - 14,081,556 (+)NCBIChiLan1.0ChiLan1.0
KCNS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27115,775,400 - 115,786,358 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1891,316,956 - 91,327,906 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0895,070,460 - 95,078,405 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1897,251,193 - 97,254,299 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl897,251,481 - 97,252,914 (+)Ensemblpanpan1.1panPan2
KCNS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.113622,676 - 628,301 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl13623,424 - 624,857 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha13615,971 - 621,592 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.013772,292 - 777,913 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl13772,281 - 778,915 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.113614,747 - 620,370 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.013722,944 - 728,562 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.013729,263 - 734,886 (+)NCBIUU_Cfam_GSD_1.0
KCNS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl438,361,347 - 38,367,695 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1438,362,882 - 38,374,415 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KCNS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1893,343,847 - 93,349,828 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl893,344,822 - 93,346,255 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603947,389,070 - 47,395,077 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcns2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247635,544,104 - 5,546,691 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247635,544,102 - 5,550,595 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005316309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000021385   ⟹   ENSSTOP00000021457
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647044,456,526 - 44,460,327 (-)Ensembl
RefSeq Acc Id: XM_005316309   ⟹   XP_005316366
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530337,028,375 - 37,034,228 (-)NCBI
SpeTri2.0NW_00493647044,455,117 - 44,460,193 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005316366 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000021457.1
GenBank Protein KAG3273846 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005316366   ⟸   XM_005316309
- UniProtKB: I3NAR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000021457   ⟸   ENSSTOT00000021385
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000024646 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000021385.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv9 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene Kcns2 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY S MEMBER 2 UniProtKB/TrEMBL
  PTHR11537 UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
PRINTS KCHANNEL UniProtKB/TrEMBL
  KV9CHANNEL UniProtKB/TrEMBL
  KVCHANNEL UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt I3NAR0 ENTREZGENE, UniProtKB/TrEMBL