Cdk2 (cyclin dependent kinase 2) - Rat Genome Database

Name: Cdk2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Cdk2 (cyclin dependent kinase 2) Ictidomys tridecemlineatus

Analyze

Symbol:

Cdk2

Name:

cyclin dependent kinase 2

RGD ID:

12572193

Description:

ENCODES a protein that exhibits cyclin binding (ortholog); cyclin-dependent protein serine/threonine kinase activity (ortholog); histone kinase activity (ortholog); INVOLVED IN animal organ regeneration (ortholog); cellular response to insulin stimulus (ortholog); DNA damage response (ortholog); PARTICIPATES IN G1/S transition pathway; interleukin-2 signaling pathway; mTOR signaling pathway; ASSOCIATED WITH breast cancer (ortholog); Embryo Loss (ortholog); Endometrial Neoplasms (ortholog); FOUND IN Cajal body (inferred); centrosome (inferred); chromosome, telomeric region (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cyclin dependent kinase 2, transcript variant X1; cyclin dependent kinase 2, transcript variant X2; cyclin-dependent kinase 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	58,484,370 - 58,490,389 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936646	379,842 - 385,877 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936646	379,849 - 385,648 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast cancer (ISO)

Embryo Loss (ISO)

Endometrial Neoplasms (ISO)

Endometrioid Carcinomas (ISO)

Experimental Liver Cirrhosis (ISO)

Experimental Mammary Neoplasms (ISO)

genetic disease (ISO)

Habitual Abortions (ISO)

head and neck squamous cell carcinoma (ISO)

Intimal Hyperplasia (ISO)

melanoma (ISO)

membranoproliferative glomerulonephritis (ISO)

Optic Nerve Injuries (ISO)

Ovarian Neoplasms (ISO)

prostate cancer (ISO)

renal cell carcinoma (ISO)

Triple Negative Breast Neoplasms (ISO)

Uterine Cervical Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ regeneration (ISO)

cellular response to insulin stimulus (ISO)

centriole replication (IEA)

chromatin remodeling (IEA)

DNA damage response (ISO)

DNA repair (IEA)

DNA-templated transcription (IEA,ISO)

G1/S transition of mitotic cell cycle (IEA,ISO)

lens development in camera-type eye (ISO)

negative regulation of protein catabolic process (ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of cell population proliferation (IEA)

positive regulation of DNA-templated DNA replication initiation (IEA,ISO)

positive regulation of DNA-templated transcription (IEA,ISO)

positive regulation of heterochromatin formation (IEA)

positive regulation of meiotic cell cycle process involved in oocyte maturation (ISO)

post-translational protein modification (IEA)

potassium ion transport (IEA,ISO)

Ras protein signal transduction (IEA)

regulation of cell cycle (IEA)

regulation of G2/M transition of mitotic cell cycle (IEA)

regulation of gene expression (IEA)

response to cadmium ion (ISO)

response to cAMP (ISO)

response to electrical stimulus (ISO)

response to estradiol (ISO)

response to ethanol (ISO)

response to organic substance (IEA)

response to toxic substance (ISO)

response to xenobiotic stimulus (ISO)

signal transduction (IEA)

Cellular Component

Cajal body (IEA)

centrosome (IEA)

chromosome, telomeric region (IEA)

condensed chromosome (IEA)

cyclin A1-CDK2 complex (IEA)

cyclin A2-CDK2 complex (IEA)

cyclin E1-CDK2 complex (IEA)

cyclin E2-CDK2 complex (IEA)

cyclin-dependent protein kinase holoenzyme complex (IEA)

cytoplasm (IEA)

endosome (IEA)

male germ cell nucleus (IEA)

nuclear envelope (IEA)

nucleoplasm (IEA)

nucleus (IEA)

transcription regulator complex (IEA)

X chromosome (IEA)

Y chromosome (IEA)

Molecular Function

ATP binding (IEA)

cyclin binding (IEA,ISO)

cyclin-dependent protein kinase activity (IEA)

cyclin-dependent protein serine/threonine kinase activity (IEA,ISO)

histone kinase activity (IEA,ISO)

kinase activity (IEA)

magnesium ion binding (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein domain specific binding (IEA)

protein kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

protein-containing complex binding (ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

G1/S transition pathway (ISO)

interleukin-2 signaling pathway (ISO)

mTOR signaling pathway (ISO)

p53 signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Cdk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	58,484,370 - 58,490,389 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936646	379,842 - 385,877 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936646	379,849 - 385,648 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDK2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	55,966,830 - 55,972,789 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	55,966,781 - 55,972,789 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	56,360,614 - 56,366,573 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	54,646,826 - 54,652,835 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	54,646,825 - 54,652,834	NCBI
Celera	12	56,013,264 - 56,019,276 (+)	NCBI		Celera
Cytogenetic Map	12	q13.2	NCBI
HuRef	12	53,399,466 - 53,405,479 (+)	NCBI		HuRef
CHM1_1	12	56,327,689 - 56,333,679 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	55,933,893 - 55,939,852 (+)	NCBI		T2T-CHM13v2.0

Cdk2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	128,533,807 - 128,540,920 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	128,533,808 - 128,540,900 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	128,697,938 - 128,705,051 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	128,697,939 - 128,705,031 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	128,134,995 - 128,142,107 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	128,100,888 - 128,107,961 (-)	NCBI		MGSCv36	mm8
Celera	10	131,090,071 - 131,097,183 (-)	NCBI		Celera
Cytogenetic Map	10	D3	NCBI
cM Map	10	77.13	NCBI

Cdk2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	1,714,392 - 1,721,964 (-)	NCBI		GRCr8
mRatBN7.2	7	1,129,878 - 1,137,431 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	1,129,811 - 1,137,403 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	3,893,030 - 3,900,519 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	5,768,702 - 5,776,191 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	6,065,517 - 6,073,007 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	3,124,953 - 3,132,533 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	3,124,954 - 3,132,457 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	3,097,653 - 3,105,210 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	2,000,196 - 2,007,682 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	2,000,196 - 2,007,682 (-)	NCBI
Celera	7	1,000,083 - 1,007,560 (-)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

Cdk2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	3,555,603 - 3,562,120 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955458	3,555,603 - 3,561,063 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDK2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	38,356,902 - 38,362,969 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	38,353,674 - 38,359,695 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	32,940,225 - 32,946,236 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	33,189,934 - 33,195,945 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	33,189,934 - 33,195,945 (-)	Ensembl	panpan1.1		panPan2

CDK2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	300,863 - 306,546 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	300,903 - 305,438 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	362,779 - 368,479 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	307,657 - 313,366 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	307,694 - 312,540 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	285,465 - 291,170 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	528,243 - 533,942 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	652,514 - 658,220 (+)	NCBI		UU_Cfam_GSD_1.0

CDK2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	21,365,764 - 21,372,168 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	21,365,723 - 21,372,170 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	22,941,174 - 22,947,591 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDK2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	51,905,085 - 51,910,209 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	51,905,115 - 51,909,907 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	194,076,082 - 194,082,105 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdk2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624802	12,076,443 - 12,082,630 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624802	12,076,443 - 12,082,608 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005335606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005335607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000000295 ⟹ ENSSTOP00000000264

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936646	379,842 - 385,877 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000034134 ⟹ ENSSTOP00000028881

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936646	379,842 - 385,647 (+)	Ensembl

RefSeq Acc Id:

XM_005335606 ⟹ XP_005335663

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	58,484,370 - 58,490,389 (-)	NCBI
SpeTri2.0	NW_004936646	379,849 - 385,648 (+)	NCBI

Sequence:

show sequence

GGCCTCTGGTGGCGGTCGGGAACTGGTGGGGGAGGCGGCAACATTGTTTCAAGTTGGACAAATT
GACAAGAGCCAGACGTAGACTGCGTTCCATCCCGACCTGGGGCTACGGTGCTGAGCTCTGTTTC
CCCCTCCTCCGCCTCCGAGAGTCAGGGCCCGCTTTCTGCAGGGTTCCCAGGCCCCCGCTCCAGG
GCCGGGCGACCCTACTCTCTAGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAAATCGGAGAG
GGCACGTACGGAGTTGTGTACAAAGCCAAAAACAAGTTAACGGGAGAAGTGGTGGCGCTTAAGA
AAATCCGCCTGGACACTGAGACTGAGGGTGTACCTAGTACTGCCATCCGTGAGATCTCTCTGCT
CAAGGAACTTAACCACCCTAATATTGTCAAGCTGCTTGATGTCATCCACACAGAAAATAAACTC
TACCTGGTTTTTGAATTTTTGCACCAAGATCTTAAGAAATTCATGGATGCCTCTGCCCTCACTG
GCATTCCTCTTCCCCTCATCAAGAGCTATCTATTTCAGCTGCTTCAGGGCCTAGCTTTCTGCCA
TTCTCATCGGGTCCTGCACCGAGACCTTAAACCTCAGAATCTGCTTATCAATGCAGAGGGGGCC
ATCAAACTAGCAGACTTTGGATTAGCCAGAGCCTTTGGAGTCCCTGTTCGTACATATACCCATG
AGGTGGTAACACTATGGTATCGGGCACCAGAAATCCTTCTGGGATGCAAATACTACTCCACAGC
AGTGGACATCTGGAGCCTGGGCTGTATCTTTGCAGAGATGCACCTAGTGTGTACCCAGCACCAT
GCTAAGTGCTGTGGGGAACACAGAAGAAATGGAAGACACAGTCTCTGCCCGCTGTGCTCCTATC
TAGAAGTGGCTGCATCACAAGGAGGGGGGATGACCGCAGTGTCTACCCCACACCCCGTGACCCG
CAGGGCCCTATTCCCTGGAGATTCTGAGATTGACCAGCTTTTCCGGATTTTTCGGACTCTGGGG
ACTCCAGATGAGGTGGTTTGGCCAGGAGTTACTTCTATGCCTGATTATAAGCCTAGTTTCCCCA
AATGGGCCCGGCAAGATTTTAGCAAAGTTGTACCTCCCCTGGATGAAGATGGACGAAGCTTGTT
ATCGCAAATGCTGCACTACGACCCCAACAAGAGGATTTCAGCAAAAGCAGCTCTGGCTCACCCA
TTCTTCCAAGATGTGACCAAGCCAGTACCCCACCTTCGACTCTGATGTTCTTCCCCAAGCCCTC
ACCCCCAGTCTCACTCTGTCCTCCAGTGTGGGTTTGACCTGGCTTGACTCTGGGCTATTTGGAC
TCAGGTGGGCCCTCTCATCTTTTCTGGGTGCCTTAACACTTGCCTTCCCCTCTCATCCAACCAG
CTCTGGGCATCCAGAGGTAGAGAGGAGGAATAAGTGAAAATGTAAAGAAGTTTCAGTATTAGAT
GCACTTAACTCAGCTTCTGCCACCCTTTCTCTCTTTTTTTAGTCATTGCTGAGGAGGGCTGGTT
TTCAAAACAAAACAAAACTGACTGTTCTCTCCCCACATGGGGTTTGCCATCCCAATTTCCTGCG
TTTGGGATGACCAGTTACCCCAGGCCTCCTGCTGCCACTGTTTTTGTAAGGACCAGAGGATAGC
AGGAGGCAGAGTTGGAACGTTTGAGAACCAAGCAAAACAAAACCATGGGGAGGGATCTATTTTA
AAGAATTAGGTTAAAAAATAGATCCAATCAGTTTATACCCTAGTTTTAGTGTTTCATCTTGCCT
AACAGGCTGGGAAACTCAAGACAGAGCCCCATTGGGGAAGCAGAAGAAATGATTACCTATAGAC
CCCTTGTCTGCCCCTCCTAGGGGCCAAGAGGAGTCTGGGAGGCCCAGGGGACAGGGATTGTGCT
GCACTCTGACCTGTTGCTTCACCATGGCCTTATGAGGCAGGTGAGATATTTGAATTTCTCTTTT
CCTTTTATGATTTTAGTTCTTGCCAGGGATCTCTGCTCCCATCTTCTTTGGAAGTTGTCTCTTA
CCCCATAAGAGTGAAGTTAGGGTCTGGATTTCATTTGGAGAATGCTGGTACTTTTTCAAGGTTG
TGCCTGAGTGGGGGCATTGGGAAAAAATTATTTCTTTAAAAGAAGGATGAACAATTATATTTAT
ATATCAGGTTATAGTTG

hide sequence

RefSeq Acc Id:

XM_005335607 ⟹ XP_005335664

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	58,484,370 - 58,490,388 (-)	NCBI
SpeTri2.0	NW_004936646	379,849 - 385,648 (+)	NCBI

Sequence:

show sequence

GGCCTCTGGTGGCGGTCGGGAACTGGTGGGGGAGGCGGCAACATTGTTTCAAGTTGGACAAATT
GACAAGAGCCAGACGTAGACTGCGTTCCATCCCGACCTGGGGCTACGGTGCTGAGCTCTGTTTC
CCCCTCCTCCGCCTCCGAGAGTCAGGGCCCGCTTTCTGCAGGGTTCCCAGGCCCCCGCTCCAGG
GCCGGGCGACCCTACTCTCTAGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAAATCGGAGAG
GGCACGTACGGAGTTGTGTACAAAGCCAAAAACAAGTTAACGGGAGAAGTGGTGGCGCTTAAGA
AAATCCGCCTGGACACTGAGACTGAGGGTGTACCTAGTACTGCCATCCGTGAGATCTCTCTGCT
CAAGGAACTTAACCACCCTAATATTGTCAAGCTGCTTGATGTCATCCACACAGAAAATAAACTC
TACCTGGTTTTTGAATTTTTGCACCAAGATCTTAAGAAATTCATGGATGCCTCTGCCCTCACTG
GCATTCCTCTTCCCCTCATCAAGAGCTATCTATTTCAGCTGCTTCAGGGCCTAGCTTTCTGCCA
TTCTCATCGGGTCCTGCACCGAGACCTTAAACCTCAGAATCTGCTTATCAATGCAGAGGGGGCC
ATCAAACTAGCAGACTTTGGATTAGCCAGAGCCTTTGGAGTCCCTGTTCGTACATATACCCATG
AGGTGGTAACACTATGGTATCGGGCACCAGAAATCCTTCTGGGATGCAAATACTACTCCACAGC
AGTGGACATCTGGAGCCTGGGCTGTATCTTTGCAGAGATGGTGACCCGCAGGGCCCTATTCCCT
GGAGATTCTGAGATTGACCAGCTTTTCCGGATTTTTCGGACTCTGGGGACTCCAGATGAGGTGG
TTTGGCCAGGAGTTACTTCTATGCCTGATTATAAGCCTAGTTTCCCCAAATGGGCCCGGCAAGA
TTTTAGCAAAGTTGTACCTCCCCTGGATGAAGATGGACGAAGCTTGTTATCGCAAATGCTGCAC
TACGACCCCAACAAGAGGATTTCAGCAAAAGCAGCTCTGGCTCACCCATTCTTCCAAGATGTGA
CCAAGCCAGTACCCCACCTTCGACTCTGATGTTCTTCCCCAAGCCCTCACCCCCAGTCTCACTC
TGTCCTCCAGTGTGGGTTTGACCTGGCTTGACTCTGGGCTATTTGGACTCAGGTGGGCCCTCTC
ATCTTTTCTGGGTGCCTTAACACTTGCCTTCCCCTCTCATCCAACCAGCTCTGGGCATCCAGAG
GTAGAGAGGAGGAATAAGTGAAAATGTAAAGAAGTTTCAGTATTAGATGCACTTAACTCAGCTT
CTGCCACCCTTTCTCTCTTTTTTTAGTCATTGCTGAGGAGGGCTGGTTTTCAAAACAAAACAAA
ACTGACTGTTCTCTCCCCACATGGGGTTTGCCATCCCAATTTCCTGCGTTTGGGATGACCAGTT
ACCCCAGGCCTCCTGCTGCCACTGTTTTTGTAAGGACCAGAGGATAGCAGGAGGCAGAGTTGGA
ACGTTTGAGAACCAAGCAAAACAAAACCATGGGGAGGGATCTATTTTAAAGAATTAGGTTAAAA
AATAGATCCAATCAGTTTATACCCTAGTTTTAGTGTTTCATCTTGCCTAACAGGCTGGGAAACT
CAAGACAGAGCCCCATTGGGGAAGCAGAAGAAATGATTACCTATAGACCCCTTGTCTGCCCCTC
CTAGGGGCCAAGAGGAGTCTGGGAGGCCCAGGGGACAGGGATTGTGCTGCACTCTGACCTGTTG
CTTCACCATGGCCTTATGAGGCAGGTGAGATATTTGAATTTCTCTTTTCCTTTTATGATTTTAG
TTCTTGCCAGGGATCTCTGCTCCCATCTTCTTTGGAAGTTGTCTCTTACCCCATAAGAGTGAAG
TTAGGGTCTGGATTTCATTTGGAGAATGCTGGTACTTTTTCAAGGTTGTGCCTGAGTGGGGGCA
TTGGGAAAAAATTATTTCTTTAAAAGAAGGATGAACAATTATATTTATATATCAGGTTATAGTT
G

hide sequence

Protein Sequences


Protein RefSeqs	XP_005335663	(Get FASTA)	NCBI Sequence Viewer
	XP_005335664	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000000264.2
	ENSSTOP00000028881.1
GenBank Protein	KAG3291661	(Get FASTA)	NCBI Sequence Viewer
	KAG3291662	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005335663 ⟸ XM_005335606
- Peptide Label:	isoform X1
- UniProtKB:	A0A287D5T7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIV KLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDL KPQNLLINAEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCI FAEMHLVCTQHHAKCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVSTPHPVTRRALFPGDSE IDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPN KRISAKAALAHPFFQDVTKPVPHLRL hide sequence

RefSeq Acc Id:	XP_005335664 ⟸ XM_005335607
- Peptide Label:	isoform X2
- UniProtKB:	I3LWC0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIV KLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDL KPQNLLINAEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCI FAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLD EDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL hide sequence

RefSeq Acc Id:

ENSSTOP00000000264 ⟸ ENSSTOT00000000295

RefSeq Acc Id:

ENSSTOP00000028881 ⟸ ENSSTOT00000034134

Protein Domains

Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000000298	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000000295.3	UniProtKB/TrEMBL
	ENSSTOT00000034134.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
NCBI Gene	Cdk2	ENTREZGENE
PANTHER	CELL DIVISION PROTEIN KINASE	UniProtKB/TrEMBL
	CYCLIN-DEPENDENT KINASE 2	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A287D5T7	ENTREZGENE, UniProtKB/TrEMBL
	I3LWC0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)