Kcnq3 (potassium voltage-gated channel subfamily Q member 3) - Rat Genome Database

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Gene: Kcnq3 (potassium voltage-gated channel subfamily Q member 3) Ictidomys tridecemlineatus
Analyze
Symbol: Kcnq3
Name: potassium voltage-gated channel subfamily Q member 3
RGD ID: 12560984
Description: ENCODES a protein that exhibits calmodulin binding (ortholog); protein kinase binding (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN action potential initiation (ortholog); apoptosome assembly (ortholog); cellular response to ammonium ion (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); benign epilepsy with centrotemporal spikes (ortholog); FOUND IN axon initial segment (ortholog); cell surface (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel subfamily KQT member 3; potassium voltage-gated channel, KQT-like subfamily, member 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053039,286,465 - 9,587,259 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647016,712,703 - 17,009,397 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647016,712,508 - 17,009,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnq3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053039,286,465 - 9,587,259 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647016,712,703 - 17,009,397 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647016,712,508 - 17,009,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNQ3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388132,120,861 - 132,481,095 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8132,120,861 - 132,481,095 (-)EnsemblGRCh38hg38GRCh38
GRCh378133,133,108 - 133,493,342 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368133,210,438 - 133,562,186 (-)NCBINCBI36Build 36hg18NCBI36
Build 348133,210,437 - 133,562,186NCBI
Celera8129,316,946 - 129,668,720 (-)NCBICelera
Cytogenetic Map8q24.22NCBI
HuRef8128,450,644 - 128,810,822 (-)NCBIHuRef
CHM1_18133,173,913 - 133,533,807 (-)NCBICHM1_1
T2T-CHM13v2.08133,243,767 - 133,604,173 (-)NCBIT2T-CHM13v2.0
Kcnq3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391565,858,223 - 66,158,485 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1565,858,236 - 66,158,491 (-)EnsemblGRCm39 Ensembl
GRCm381565,986,374 - 66,286,636 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1565,986,387 - 66,286,642 (-)EnsemblGRCm38mm10GRCm38
MGSCv371565,826,477 - 66,117,786 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361565,824,844 - 66,115,893 (-)NCBIMGSCv36mm8
Celera1567,502,496 - 67,809,639 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1529.16NCBI
Kcnq3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8799,614,089 - 99,914,736 (-)NCBIGRCr8
mRatBN7.2797,730,219 - 98,025,652 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl797,730,465 - 98,025,653 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx799,483,729 - 99,777,542 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07101,685,392 - 101,979,218 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07101,604,737 - 101,898,571 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07106,714,479 - 107,009,639 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7106,717,229 - 107,009,330 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07106,662,621 - 106,956,409 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47103,325,185 - 103,627,045 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17103,359,425 - 103,661,275 (-)NCBI
Celera794,285,105 - 94,579,630 (-)NCBICelera
Cytogenetic Map7q33NCBI
Kcnq3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554616,797,018 - 7,119,569 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554616,793,877 - 7,119,859 (-)NCBIChiLan1.0ChiLan1.0
KCNQ3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27149,504,271 - 149,869,035 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18125,018,869 - 125,383,609 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08128,769,930 - 129,134,671 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18131,747,069 - 132,110,448 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8131,755,454 - 131,815,237 (-)Ensemblpanpan1.1panPan2
KCNQ3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11328,765,472 - 29,062,371 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1328,773,738 - 29,062,370 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1328,738,298 - 29,035,933 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01329,120,132 - 29,417,368 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1329,126,114 - 29,417,147 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11328,847,191 - 29,144,520 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01328,946,895 - 29,244,508 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01329,258,881 - 29,556,646 (-)NCBIUU_Cfam_GSD_1.0
KCNQ3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl48,669,121 - 8,970,342 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.148,669,969 - 8,978,656 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.248,707,508 - 9,006,805 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNQ3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18126,566,288 - 126,921,354 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8126,566,545 - 126,622,712 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603913,185,447 - 13,545,986 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnq3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473523,441,042 - 23,751,247 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473523,441,042 - 23,752,197 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005316145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000011132   ⟹   ENSSTOP00000009986
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647016,712,703 - 17,009,397 (+)Ensembl
RefSeq Acc Id: XM_005316145   ⟹   XP_005316202
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244053039,286,465 - 9,587,259 (+)NCBI
SpeTri2.0NW_00493647016,712,508 - 17,009,648 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005316202 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000009986.3
GenBank Protein KAG3273576 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005316202   ⟸   XM_005316145
- UniProtKB: I3MGR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000009986   ⟸   ENSSTOT00000011132
Protein Domains
Ion transport   Potassium channel voltage dependent KCNQ C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011130 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011132.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  6.10.140.1910 UniProtKB/TrEMBL
InterPro Ankyrin-G_BS UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_KCNQ UniProtKB/TrEMBL
  K_chnl_volt-dep_KCNQ3 UniProtKB/TrEMBL
  K_chnl_volt-dep_KCNQ_C UniProtKB/TrEMBL
NCBI Gene Kcnq3 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 3 UniProtKB/TrEMBL
  POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
  KCNQ_channel UniProtKB/TrEMBL
  KCNQC3-Ank-G_bd UniProtKB/TrEMBL
PRINTS KCHANNEL UniProtKB/TrEMBL
  KCNQ3CHANNEL UniProtKB/TrEMBL
  KCNQCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt I3MGR4 ENTREZGENE, UniProtKB/TrEMBL