Nrxn1 (neurexin 1) - Rat Genome Database

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Gene: Nrxn1 (neurexin 1) Ictidomys tridecemlineatus
Analyze
Symbol: Nrxn1
Name: neurexin 1
RGD ID: 12545890
Description: ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); calcium channel regulator activity (ortholog); calcium ion binding (ortholog); INVOLVED IN adult behavior (ortholog); calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (ortholog); cellular response to calcium ion (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); CHROMOSOME 2p16.3 DELETION SYNDROME (ortholog); FOUND IN axonal growth cone (ortholog); cell surface (ortholog); endocytic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neurexin-1; neurexin-1-beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629230,455,821 - 31,526,486 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365081,889,640 - 2,954,039 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult behavior  (ISO)
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules  (ISO)
cellular response to calcium ion  (ISO)
cerebellar granule cell differentiation  (ISO)
chemical synaptic transmission  (ISO)
circadian rhythm  (ISO)
establishment of protein localization  (ISO)
filopodium assembly  (ISO)
gamma-aminobutyric acid receptor clustering  (ISO)
gephyrin clustering involved in postsynaptic density assembly  (ISO)
guanylate kinase-associated protein clustering  (ISO)
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  (ISO)
learning  (ISO)
negative regulation of filopodium assembly  (ISO)
negative regulation of gene expression  (ISO)
neuroligin clustering involved in postsynaptic membrane assembly  (ISO)
neuromuscular process controlling balance  (ISO)
neuron cell-cell adhesion  (ISO)
neuron maturation  (ISO)
neuron projection development  (ISO)
neurotransmitter secretion  (ISO)
NMDA glutamate receptor clustering  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of excitatory postsynaptic potential  (ISO)
positive regulation of fibroblast growth factor receptor signaling pathway  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of protein kinase A signaling  (ISO)
positive regulation of protein localization to plasma membrane  (ISO)
positive regulation of synapse assembly  (ISO)
positive regulation of synapse maturation  (ISO)
positive regulation of synaptic transmission, glutamatergic  (ISO)
postsynaptic density protein 95 clustering  (ISO)
postsynaptic membrane assembly  (ISO)
prepulse inhibition  (ISO)
presynapse assembly  (ISO)
presynaptic membrane assembly  (ISO)
protein localization to synapse  (ISO)
protein-containing complex assembly involved in synapse maturation  (ISO)
receptor localization to synapse  (ISO)
regulation of grooming behavior  (ISO)
regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
regulation of postsynaptic density assembly  (ISO)
regulation of postsynaptic specialization assembly  (ISO)
regulation of presynapse assembly  (ISO)
regulation of synaptic vesicle cycle  (ISO)
regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission  (ISO)
signal transduction  (ISO)
social behavior  (ISO)
synapse assembly  (ISO)
synaptic membrane adhesion  (ISO)
synaptic vesicle clustering  (ISO)
vesicle docking involved in exocytosis  (ISO)
vocal learning  (ISO)
vocalization behavior  (ISO)

References

Genomics

Comparative Map Data
Nrxn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629230,455,821 - 31,526,486 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365081,889,640 - 2,954,039 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NRXN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38249,918,503 - 51,032,132 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl249,918,503 - 51,225,575 (-)EnsemblGRCh38hg38GRCh38
GRCh37250,145,641 - 51,259,270 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36250,000,992 - 51,113,178 (-)NCBINCBI36Build 36hg18NCBI36
Build 34250,059,138 - 50,486,545NCBI
Celera249,985,850 - 51,099,841 (-)NCBICelera
Cytogenetic Map2p16.3NCBI
HuRef249,879,094 - 50,994,141 (-)NCBIHuRef
CHM1_1250,076,199 - 51,190,490 (-)NCBICHM1_1
T2T-CHM13v2.0249,914,520 - 51,028,290 (-)NCBIT2T-CHM13v2.0
Nrxn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391790,341,072 - 91,400,587 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1790,341,059 - 91,400,499 (-)EnsemblGRCm39 Ensembl
GRCm381790,033,644 - 91,093,159 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1790,033,631 - 91,093,071 (-)EnsemblGRCm38mm10GRCm38
MGSCv371790,432,984 - 91,492,142 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361790,433,296 - 91,492,142 (-)NCBIMGSCv36mm8
Celera1794,417,402 - 95,489,954 (-)NCBICelera
Cytogenetic Map17E5NCBI
cM Map1759.73NCBI
Nrxn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr868,931,360 - 10,077,381 (+)NCBIGRCr8
mRatBN7.263,177,788 - 4,323,848 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl63,177,897 - 4,322,710 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx63,476,659 - 4,613,908 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.063,786,080 - 4,923,338 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.063,310,521 - 4,447,776 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0613,886,757 - 15,191,660 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl613,886,740 - 15,191,660 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0624,704,937 - 25,145,167 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0623,843,153 - 24,482,073 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4614,050,929 - 15,354,069 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1615,245,705 - 15,354,069 (-)NCBI
Celera62,975,004 - 4,118,378 (+)NCBICelera
Cytogenetic Map6q11-q12NCBI
Nrxn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544116,234,070 - 17,178,005 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544116,230,977 - 17,178,003 (-)NCBIChiLan1.0ChiLan1.0
NRXN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21275,325,549 - 76,440,534 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A75,329,515 - 76,444,501 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A50,063,398 - 51,178,659 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A50,981,997 - 52,095,538 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A50,985,067 - 52,091,277 (-)Ensemblpanpan1.1panPan2
NRXN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11051,555,660 - 52,666,774 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1051,558,452 - 52,667,569 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1051,401,804 - 52,511,290 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01052,431,369 - 53,560,787 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1052,431,572 - 53,564,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11052,126,286 - 53,234,452 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01052,413,764 - 53,524,238 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01052,609,896 - 53,719,985 (-)NCBIUU_Cfam_GSD_1.0
NRXN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl389,803,519 - 90,382,034 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1389,799,426 - 90,914,205 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2395,543,189 - 96,298,412 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NRXN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11456,051,849 - 57,202,334 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604554,638,899 - 55,766,868 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nrxn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473831,133,346 - 32,273,565 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473831,134,551 - 32,273,596 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: XM_040271319   ⟹   XP_040127253
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629230,455,821 - 31,526,486 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040127253 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3267331 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_040127253   ⟸   XM_040271319


Additional Information

Database Acc Id Source(s)
NCBI Gene Nrxn1 ENTREZGENE