Add3 (adducin 3) - Rat Genome Database

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Gene: Add3 (adducin 3) Ictidomys tridecemlineatus
Analyze
Symbol: Add3
Name: adducin 3
RGD ID: 12540040
Description: ENCODES a protein that exhibits protein kinase C binding (ortholog); INVOLVED IN positive regulation of cytoskeleton organization (ortholog); positive regulation of vasoconstriction (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); brain ischemia (ortholog); cerebral palsy (ortholog); FOUND IN brush border (inferred); cell cortex (inferred); cell-cell junction (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adducin 3, transcript variant X1; adducin 3, transcript variant X2; adducin 3, transcript variant X3; adducin 3, transcript variant X4; adducin 3, transcript variant X5; adducin 3, transcript variant X6; adducin 3, transcript variant X7; gamma-adducin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721324,519,105 - 24,632,420 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936486928,522 - 1,043,084 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936486928,956 - 1,042,168 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Add3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721324,519,105 - 24,632,420 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936486928,522 - 1,043,084 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936486928,956 - 1,042,168 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810109,996,373 - 110,135,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10109,996,368 - 110,135,565 (+)EnsemblGRCh38hg38GRCh38
GRCh3710111,756,131 - 111,895,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610111,755,716 - 111,885,313 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410111,755,793 - 111,885,313NCBI
Celera10105,497,404 - 105,626,995 (+)NCBICelera
Cytogenetic Map10q25.1-q25.2NCBI
HuRef10105,396,619 - 105,526,176 (+)NCBIHuRef
CHM1_110112,047,392 - 112,177,067 (+)NCBICHM1_1
T2T-CHM13v2.010110,880,187 - 111,019,428 (+)NCBIT2T-CHM13v2.0
Add3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391953,128,874 - 53,235,518 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1953,128,874 - 53,235,830 (+)EnsemblGRCm39 Ensembl
GRCm381953,140,443 - 53,247,326 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1953,140,443 - 53,247,399 (+)EnsemblGRCm38mm10GRCm38
MGSCv371953,214,935 - 53,321,889 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361953,256,726 - 53,300,399 (+)NCBIMGSCv36mm8
Celera1955,321,358 - 55,428,774 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1947.18NCBI
Add3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81262,152,722 - 262,260,504 (+)NCBIGRCr8
mRatBN7.21252,147,341 - 252,255,126 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1252,147,386 - 252,255,124 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1260,336,161 - 260,443,763 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01267,042,224 - 267,149,829 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01259,697,436 - 259,805,286 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01273,854,195 - 273,961,982 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1273,854,248 - 273,961,982 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01281,267,424 - 281,375,203 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41259,347,673 - 259,455,407 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11259,560,471 - 259,923,891 (-)NCBI
Celera1247,872,140 - 247,979,623 (+)NCBICelera
Cytogenetic Map1q55NCBI
Add3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554851,216,435 - 1,353,953 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554851,216,435 - 1,273,275 (-)NCBIChiLan1.0ChiLan1.0
ADD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28121,884,928 - 122,014,764 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110121,890,333 - 122,020,100 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010106,597,693 - 106,727,494 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110110,048,680 - 110,178,671 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10110,123,270 - 110,178,671 (+)Ensemblpanpan1.1panPan2
ADD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12821,402,068 - 21,527,006 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2821,403,680 - 21,525,063 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2821,545,130 - 21,669,800 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02821,916,580 - 22,041,306 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2821,875,987 - 22,041,302 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12821,477,401 - 21,602,290 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02821,481,987 - 21,606,180 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02821,617,201 - 21,742,113 (+)NCBIUU_Cfam_GSD_1.0
ADD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14120,451,575 - 120,583,722 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114120,451,421 - 120,583,725 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214131,288,509 - 131,420,807 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19102,930,270 - 103,056,558 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9103,010,713 - 103,057,101 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604864,133,099 - 64,259,617 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Add3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473736,091,671 - 36,256,398 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000024099   ⟹   ENSSTOP00000017678
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936486928,522 - 1,043,084 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000034725   ⟹   ENSSTOP00000029028
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936486930,559 - 1,043,084 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000035492   ⟹   ENSSTOP00000024986
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364861,011,919 - 1,042,168 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000036938   ⟹   ENSSTOP00000032114
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936486930,559 - 1,043,084 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000042207   ⟹   ENSSTOP00000026244
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364861,000,260 - 1,043,084 (+)Ensembl
RefSeq Acc Id: XM_013356556   ⟹   XP_013212010
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,632,420 (-)NCBI
SpeTri2.0NW_004936486928,956 - 1,042,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013356557   ⟹   XP_013212011
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,632,420 (-)NCBI
SpeTri2.0NW_004936486928,956 - 1,042,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013356558   ⟹   XP_013212012
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,630,330 (-)NCBI
SpeTri2.0NW_004936486930,908 - 1,042,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723287   ⟹   XP_021578962
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,629,921 (-)NCBI
SpeTri2.0NW_004936486931,288 - 1,042,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040271681   ⟹   XP_040127615
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,627,036 (-)NCBI
RefSeq Acc Id: XM_040271682   ⟹   XP_040127616
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,571,480 (-)NCBI
RefSeq Acc Id: XM_040271684   ⟹   XP_040127618
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,586,208 (-)NCBI
RefSeq Acc Id: XM_040271685   ⟹   XP_040127619
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,549,388 (-)NCBI
RefSeq Acc Id: XM_040271686   ⟹   XP_040127620
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,632,419 (-)NCBI
RefSeq Acc Id: XM_040271687   ⟹   XP_040127621
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,519,105 - 24,549,383 (-)NCBI
RefSeq Acc Id: XM_040271688   ⟹   XP_040127622
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440721324,521,194 - 24,632,418 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013212011   ⟸   XM_013356557
- Peptide Label: isoform X1
- UniProtKB: I3MZY2 (UniProtKB/TrEMBL),   A0A287DEZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013212010   ⟸   XM_013356556
- Peptide Label: isoform X1
- UniProtKB: I3MZY2 (UniProtKB/TrEMBL),   A0A287DEZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013212012   ⟸   XM_013356558
- Peptide Label: isoform X1
- UniProtKB: I3MZY2 (UniProtKB/TrEMBL),   A0A287DEZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021578962   ⟸   XM_021723287
- Peptide Label: isoform X1
- UniProtKB: I3MZY2 (UniProtKB/TrEMBL),   A0A287DEZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040127620   ⟸   XM_040271686
- Peptide Label: isoform X2
- UniProtKB: A0A287CUN3 (UniProtKB/TrEMBL),   A0A287DEZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127615   ⟸   XM_040271681
- Peptide Label: isoform X1
- UniProtKB: I3MZY2 (UniProtKB/TrEMBL),   A0A287DEZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127618   ⟸   XM_040271684
- Peptide Label: isoform X1
- UniProtKB: I3MZY2 (UniProtKB/TrEMBL),   A0A287DEZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127616   ⟸   XM_040271682
- Peptide Label: isoform X1
- UniProtKB: I3MZY2 (UniProtKB/TrEMBL),   A0A287DEZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127619   ⟸   XM_040271685
- Peptide Label: isoform X1
- UniProtKB: I3MZY2 (UniProtKB/TrEMBL),   A0A287DEZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127621   ⟸   XM_040271687
- Peptide Label: isoform X3
- UniProtKB: A0A287DEZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127622   ⟸   XM_040271688
- Peptide Label: isoform X4
- UniProtKB: A0A287DEZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000032114   ⟸   ENSSTOT00000036938
RefSeq Acc Id: ENSSTOP00000029028   ⟸   ENSSTOT00000034725
RefSeq Acc Id: ENSSTOP00000024986   ⟸   ENSSTOT00000035492
RefSeq Acc Id: ENSSTOP00000017678   ⟸   ENSSTOT00000024099
RefSeq Acc Id: ENSSTOP00000026244   ⟸   ENSSTOT00000042207
Protein Domains
Class II aldolase/adducin N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021776 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024099.2 UniProtKB/TrEMBL
  ENSSTOT00000034725.1 UniProtKB/TrEMBL
  ENSSTOT00000035492.1 UniProtKB/TrEMBL
  ENSSTOT00000036938.1 UniProtKB/TrEMBL
  ENSSTOT00000042207.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.225.10 UniProtKB/TrEMBL
InterPro Aldolase_II/adducin_N UniProtKB/TrEMBL
  Aldolase_II/adducin_N_sf UniProtKB/TrEMBL
NCBI Gene Add3 ENTREZGENE
PANTHER ADDUCIN UniProtKB/TrEMBL
  PTHR10672:SF5 UniProtKB/TrEMBL
Pfam Aldolase_II UniProtKB/TrEMBL
SMART Aldolase_II UniProtKB/TrEMBL
Superfamily-SCOP SSF53639 UniProtKB/TrEMBL
UniProt A0A287CUN3 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DEZ0 ENTREZGENE, UniProtKB/TrEMBL
  I3MZY2 ENTREZGENE, UniProtKB/TrEMBL